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See detailAnti-HPV vaccination : perspectives and potential consequences for the screening of cervical cancer
Delvenne, Philippe ULiege

in Annales de Pathologie (2006), 26(Sp. Iss. 1), 41-42

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See detailAnti-Ia treatment prevents lupus-like autoimmune syndrome in mice neonatally tolerized to alloantigens.
Kramar, G.; Schurmans, Stéphane ULiege; Aguado, T. et al

in Journal of Autoimmunity (1993), 1

Neonatal injection of semi-allogeneic F1 spleen cells into newborn parental mice results in induction of tolerance to the corresponding class I alloantigen and chimerism. This state of tolerance is ... [more ▼]

Neonatal injection of semi-allogeneic F1 spleen cells into newborn parental mice results in induction of tolerance to the corresponding class I alloantigen and chimerism. This state of tolerance is associated with the development of a transient lupus-like autoimmune syndrome. Previous experiments performed in our laboratories have shown that host CD4+ T lymphocytes and donor B cells persist in the host and are essential in triggering the autoimmune syndrome observed in neonatally tolerized mice. In this study, we show that early treatment of tolerized mice with anti-donor MHC class II mAb totally prevents the lupus-like syndrome. Moreover, delayed treatment significantly decreases, but to a lesser extent, autoimmune pathological features in tolerized mice. Taken together, these results show that lupus-like autoimmune syndrome developed by neonatally tolerized mice is efficiently prevented by anti-Ia treatment without interfering with the induction of tolerance [less ▲]

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See detailAnti-IgE: a significant breakthrough in the treatment of airway allergic diseases
Louis, Renaud ULiege

in Allergy (2004), 59(7), 698-700

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See detailLes anti-inflammatoires non stéroïdiens
Malaise, Michel ULiege

in Revue Médicale de Liège (1996), 51(1), 123-125

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See detailAnti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease.
Esser, Nathalie ULiege; Paquot, Nicolas ULiege; Scheen, André ULiege

in Expert opinion on investigational drugs (2015), 24(3), 283-307

Introduction: There is a growing body of evidence to suggest that chronic silent inflammation is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and cardiovascular disease ... [more ▼]

Introduction: There is a growing body of evidence to suggest that chronic silent inflammation is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and cardiovascular disease (CVD). These observations suggest that pharmacological strategies, which reduce inflammation, may be therapeutically useful in treating obesity, type 2 diabetes and associated CVD. Area covered: The article covers novel strategies, using either small molecules or monoclonal antibodies. These strategies include: approaches targeting IKK-b-NF-kB (salicylates, salsalate), TNF-alpha (etanercept, infliximab, adalimumab), IL-1beta (anakinra, canakinumab) and IL-6 (tocilizumab), AMP-activated protein kinase activators, sirtuin-1 activators, mammalian target of rapamycin inhibitors and C-C motif chemokine receptor 2 antagonists. Expert opinion: The available data supports the concept that targeting inflammation improves insulin sensitivity and beta-cell function; it also ameliorates glucose control in insulin-resistant patients with inflammatory rheumatoid diseases as well in patients with metabolic syndrome or T2DM. Although promising, the observed metabolic effects remain rather modest in most clinical trials. The potential use of combined anti-inflammatory agents targeting both insulin resistance and insulin secretion appears appealing but remains unexplored. Large-scale prospective clinical trials are underway to investigate the safety and efficacy of different anti-inflammatory drugs. Further evidence is needed to support the concept that targeting inflammation pathways may represent a valuable option to tackle the cardiometabolic complications of obesity. [less ▲]

Detailed reference viewed: 86 (12 ULiège)
See detailAnti-inflammatory and anti-oxidative feed ingredients
Lekeux, Pierre ULiege; de Moffarts

in Lindner, A. (Ed.) Applied Equine Nutrition, Equine Nutrition Conference (ENUCO) (2005)

Detailed reference viewed: 26 (2 ULiège)
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See detailAnti-inflammatory and chondroprotective activity of prodelphinidins isolated from Ribes nigrum leaves.
Tits, Monique ULiege; de Leval, Xavier; Diercksens, Yves et al

Poster (2000)

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See detailAnti-Inflammatory and Immunological Effects of Centaurea Cyanus Flower-Heads
Garbacki, Nancy ULiege; Gloaguen, Vincent; Damas, Jacques ULiege et al

in Journal of Ethnopharmacology (1999), 68(1-3), 235-41

Centaurea cyanus flower-heads are used in European phytotherapy for the treatment of minor ocular inflammations. Different pharmacological experiments (inhibition of carrageenan, zymosan and croton oil ... [more ▼]

Centaurea cyanus flower-heads are used in European phytotherapy for the treatment of minor ocular inflammations. Different pharmacological experiments (inhibition of carrageenan, zymosan and croton oil-induced oedemas, inhibition of plasma haemolytic activity, induction of anaphylatoxin activity) showed that polysaccharides extracted from C. cyanus flower-heads had anti-inflammatory properties and interfered with complement. Moreover, these polysaccharides were found to be mainly composed of galacturonic acid, arabinose, glucose, rhamnose and galactose. [less ▲]

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See detailAnti-inflammatory effect of natural proanthocyanidins: pharmacological evaluation on in vivo models.
Garbacki, Nancy ULiege; Tits, Monique ULiege; Damas, Jacques ULiege

in Pflügers Archiv : European Journal of Physiology (2003), 446

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See detailAnti-inflammatory effects of Centaurea cyanus (Asteraceae) flower-heads.
Garbacki, Nancy ULiege; Gloaguen, Vincent; Damas, Jacques ULiege et al

Poster (2001)

Detailed reference viewed: 33 (2 ULiège)
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See detailAnti-inflammatory effects of formoterol and ipratropium bromide against acute cadmium-induced pulmonary inflammation in rats.
Zhang, W.; Fievez, Laurence ULiege; Cheu, Esteban ULiege et al

in European Journal of Pharmacology (2010), 628(1-3), 171-178

In this study, the anti-inflammatory properties of formoterol and ipratropium bromide, alone or in combination, were investigated in a rat model of acute pulmonary inflammation induced by cadmium ... [more ▼]

In this study, the anti-inflammatory properties of formoterol and ipratropium bromide, alone or in combination, were investigated in a rat model of acute pulmonary inflammation induced by cadmium inhalation. Airway resistance and inflammatory responses, including matrix metalloproteinease-2 (MMP-2) and matrix metalloproteinease-9 (MMP-9) activities, were evaluated. Compared to values obtained in rats exposed to cadmium, pretreatment by bronchodilators administered alone significantly prevented the cadmium-induced increase of airway resistance. Formoterol elicited a significant decrease in total cell number, neutrophil and macrophage counts in bronchoalveolar lavage fluid, whereas ipratropium bromide reduced neutrophil numbers. The two compounds administered alone significantly attenuated the lung lesions associated with parenchyma inflammatory cell influx and congestion observed in the cadmium group. The increased MMP-9 activity was significantly attenuated. Although only formoterol induced a decrease protein concentration in bronchoalveolar lavage fluid, both compounds inhibited the pulmonary edema by reducing wet-to-dry weight ratio which returned to values similar to those recorded in the sham group. All the effects of formoterol on the cadmium-induced inflammatory responses were reversed by propranolol. Similar anti-inflammatory effects were obtained in rats pretreated with ilomastat which showed a significant reduction on inflammatory cell infiltration and MMP-9 activity in bronchoalveolar lavage fluid. Neither synergistic nor additive effects were obtained when the two bronchodilators were administered in combination. In conclusion, formoterol and ipratropium bromide partially protect the lungs against the inflammation by reducing neutrophilic infiltration. This protective effect is associated with reduced MMP-9 activity known to play an important pro-inflammatory role in acute inflammatory process. [less ▲]

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See detailAnti-inflammatory effects of formoterol in rats after a single dose inhalation of nebulized cadmium
Zhang, W. H.; Fievez, Laurence ULiege; Cheu, Esteban ULiege et al

in Fundamental & Clinical Pharmacology (2007), 74

Detailed reference viewed: 32 (7 ULiège)
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See detailAnti-inflammatory effects of ipratropium bromide in rats with cadmium-induced acute pulmonary inflammation
Zhang, W.; Fievez, Laurence ULiege; Cheu, Esteban ULiege et al

in Proceedings of the 12th Annual Meeting of the French Society of Pharmacology and Therapeutics (2008)

Detailed reference viewed: 39 (2 ULiège)
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See detailAnti-inflammatory effects of ipratropium bromide in rats with cadmium-induced acute pulmonary inflammation
Zhang, Yinghong ULiege; Fievez, Laurence ULiege; Cheu, Esteban ULiege et al

in Fundamental & Clinical Pharmacology (2008), 22(1), 7

Detailed reference viewed: 55 (3 ULiège)
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See detailAnti-inflammatory potency of the traditionally used antimalarial plant Fagraea fragrans
Jonville, Marie ULiege; Baghdikian, Béatrice; Ollivier, Evelyne et al

in Planta Medica (2010, September), 76(12), 1171

Detailed reference viewed: 72 (7 ULiège)
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See detailAnti-inflammatory properties of capsular polymers from blue-green algae.
Garbacki, Nancy ULiege; Gloaguen, Vincent; Damas, Jacques ULiege et al

Conference (1999)

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See detailAnti-inflammatory properties of stigmasterol in cartilage: new insights
Gabay, Odile; Sanchez, Christelle ULiege; Chevy, F. et al

Poster (2008)

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See detailAnti-inflammatory properties of stigmasterol in cartilage: new insights
Gabay, Odile; Sanchez, Christelle ULiege; Chevy, F. et al

in Osteoarthritis and Cartilage (2008), 16(Suppl 4), 79

Detailed reference viewed: 148 (3 ULiège)