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See detailLuminescence dating of architectural ceramics from an early medieval abbey: the St-Philbert intercomparison (Loire Atlantique, France)
Guibert, Pierre; Bailiff, Ian; Blain, Sophie ULg et al

in Radiation Measurements (2009), 44

An experimental intercomparison was performed with brick samples from an early medieval building in the west of France, the St-Philbert-de-Grandlieu abbey. A potentially complex set of microdosimetric ... [more ▼]

An experimental intercomparison was performed with brick samples from an early medieval building in the west of France, the St-Philbert-de-Grandlieu abbey. A potentially complex set of microdosimetric problems emerged from characterisation measurements, providing a robust test of the routine procedures used by each laboratory. The dating results obtained using quartz coarse grains and fine grain samples span over a large period of time, exhibiting overdispersion, and where systematic deviations appear between quartz and fine grain chronologies. Factors causing such scatter are analysed in detail, including internal radioactivity of quartz grains, millimetre-scale heterogeneity in the fabric, and the observation and modelling of fading behaviour of fine grain minerals. [less ▲]

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See detailLuminescence dating of ceramic building materials: application to the study of early medieval churches in north-western France and south-eastern England
Blain, Sophie ULg; Bailiff, Ian; Guibert, Pierre et al

in Martinón-Torres, Marcos (Ed.) Between craft and science: selected studies in archaeological ceramics (2014)

This study focuses on early medieval buildings in England and in France, specifically on those displaying the presence of brick in their masonry. The purpose was to determine whether medieval builders ... [more ▼]

This study focuses on early medieval buildings in England and in France, specifically on those displaying the presence of brick in their masonry. The purpose was to determine whether medieval builders reused Roman salvaged building materials or if the bricks used were contemporary to the building under construction. Thus luminescence dating was applied to bricks sampled from 11 standing Anglo-Saxon or Carolingian churches. The luminescence dates show that the two types of practice were in use in both countries. Where contemporary brickmaking appears to be the case, the study also provided a more precise chronology of the buildings. [less ▲]

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See detailLuminescence dating of the Palaeolithic site of Kulbulak (Uzbekistan) using IR50 and pIRIR290 signals from K-feldspar
Vandenberghe, Dimitri; Van Nieuland, J.; De Dapper, Morgan et al

Poster (2013, May)

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See detailLumiracoxib (Prexige) is effective in the treatment of osteoarthritis of the knee: a 13-week, placebo-controlled, active-comparator, double-blind study
Tannenbaum, Hyman; Berenbaum, Francis; Reginster, Jean-Yves ULg et al

in Arthritis and Rheumatism (2002, September), 46(number 9 (suppl.)), 212

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See detailLumiracoxib is effective in the treatment of osteoarthritis of the knee: a 13 week, randomised, double blind study versus placebo and celecoxib
Tannenbaum, H.; Berenbaum, F.; Reginster, Jean-Yves ULg et al

in Annals of the Rheumatic Diseases (2004), 63(11), 1419-1426

Objectives: To compare the efficacy and safety of lumiracoxib with placebo and celecoxib for osteoarthritis (OA) in a 13 week, multicentre, randomised, double blind study. Methods: After a 327 day washout ... [more ▼]

Objectives: To compare the efficacy and safety of lumiracoxib with placebo and celecoxib for osteoarthritis (OA) in a 13 week, multicentre, randomised, double blind study. Methods: After a 327 day washout period for non-steroidal anti-inflammatory drugs, 1702 patients with knee OA were randomised to lumiracoxib 200 or 400 mg once daily (od), celecoxib 200 mg od, or placebo (2:2:2:1). A visual analogue scale (VAS) pain intensity greater than or equal to40 mm was required. Primary efficacy variables were OA pain intensity (VAS mm) in the target knee, patient's global assessment of disease activity (VAS mm), and WOMAC pain subscale and total scores at 13 weeks. OA pain intensity, patient's and physician's global assessment of disease activity, and WOMAC (total and all subscale scores) were analysed by visit as secondary variables. Results: Lumiracoxib showed significant improvements in all primary and secondary variables compared with placebo. Lumiracoxib 200 mg od and celecoxib 200 mg od achieved similar improvements in OA pain intensity and functional status. Lumiracoxib 400 mg od demonstrated better efficacy for OA pain intensity and patient's global assessment of disease activity at weeks 2, 4, and 8 and similar efficacy at week 13 compared with celecoxib 200 mg od. The incidence of adverse events (AEs), serious AEs, and discontinuations due to AEs was similar in each group. Conclusion: Lumiracoxib demonstrated significant improvement in OA pain intensity, patient's global assessment of disease activity, and the WOMAC pain subscale and total scores compared with placebo. Lumiracoxib was well tolerated in this study, with overall tolerability similar to that of placebo and celecoxib. [less ▲]

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See detailLumumba n’est pas une figure fédératrice ! L’impensé d’une présence africaine en périphérie impériale
Demart, Sarah ULg

Scientific conference (2014)

Malgré des histoires et configurations coloniales hautement contrastées, des modèles sociétaux irréductibles, la situation belge s’inscrit à n’en pas douter dans les rails de l’« hiver impérial français » ... [more ▼]

Malgré des histoires et configurations coloniales hautement contrastées, des modèles sociétaux irréductibles, la situation belge s’inscrit à n’en pas douter dans les rails de l’« hiver impérial français » (Mbembe, 2010). La forte racialisation des personnes issues des ex-colonies afro-subsahariennes, le color-blindness étatique ou la marginalisation académique de la critique postcoloniale en sont les indicateurs majeurs. Pour autant, en Belgique, le modèle républicain, et ses prétentions universalistes, ne peut expliquer les dynamiques identitaires ni les imaginaires autochtones dont procède l’impensé de la race. Comme nous le verrons, la logique séparatiste d’une métropole en mal de légitimité impériale - qui dissocia avec force colonie et métropole et refusa de penser non seulement l’installation des Congolais en Belgique mais leur mobilité sociale - offre une lisibilité de la façon dont les frontières raciales informent, à date contemporaine, les anxiétés postcoloniales de l’autochtonie. Nous discuterons alors, à partir de données recueillies depuis une dizaine d’années au sein des milieux congolais, politiques, associatifs, religieux et artistiques, la façon dont la situation belge peut, ou pas, reformuler la particularité française sous l’angle d’une posture impériale francophone. [less ▲]

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See detailLa luna di Pola. In lingua e in dialetto
Curreri, Luciano ULg

in Dolfi, Anna (Ed.) Poesia dialettale e poesia in lingua nel Novecento. Intorno all'opera di Marco Pola (1994)

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See detailLa Lune -- P. Bianucci
Manfroid, Jean ULg

in Ciel et Terre (1990), 106

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See detailLa lune maléfique dans le Croissant des larmes de José Tshisungu wa Tshisungu
Vanhaegendoren, Koen ULg

in Vanhaegendoren, Koen (Ed.) Esthétique et politique. Autour de l’œuvre littéraire de José Tshisungu wa Tshisungu (2010)

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See detailLunettes et télescopes, l'Univers se dévoile
Jaminon, Martine ULg; Nazé, Yaël ULg; Taton, Fabrice

Learning material (2009)

Plaquette de l'exposition "Lunettes et Télescopes : l'Univers se dévoile" + animations flash illustrant la réflexion par des miroirs sphériques et la réfraction par des lentilles divergentes et ... [more ▼]

Plaquette de l'exposition "Lunettes et Télescopes : l'Univers se dévoile" + animations flash illustrant la réflexion par des miroirs sphériques et la réfraction par des lentilles divergentes et convergentes. [less ▲]

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See detaillung compliance and resistance in premature and term neonates
Battisti, Oreste ULg; bertrand, jean-marie; rouatbi, hatem et al

in Pediatrics & Therapeutics: Current Research (2012)

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See detailLung disorders in dogs and cats
Clercx, Cécile ULg

Scientific conference (2012, January)

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See detailLung Fibrosis in dogs - News about genetic background, pathology, diagnostics and therapy
Clercx, Cécile ULg

in Proceedings of 58th Annual Conference of GSAVA in Duesseldorf, Germany (2012, October 20)

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See detailLung fluid balance and septic shock
D'Orio, Vincenzo ULg; WAHLEN, C; RODRIGUEZ, LM et al

in Chicago (1975) (1989)

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See detailLung fluid balance during recovery of appropriate supply-oxygen uptake ratio with volume loading in septic shock dogs
D'Orio, Vincenzo ULg; FATEMI, M; MENDES, P et al

in American Review of Respiratory Disease (1991), 143

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See detailLung Fluid Dynamics and Supply Dependency of Oxygen Uptake During Experimental Endotoxic Shock and Volume Resuscitation
D'Orio, Vincenzo ULg; Mendes, P.; Carlier, Pierre ULg et al

in Critical Care Medicine (1991), 19(7), 955-62

BACKGROUND AND METHODS: We studied the effect of volume resuscitation on lung fluid balance and systemic oxygen extraction during septic shock in eight anesthetized dogs. Sepsis was induced using a 2-hr ... [more ▼]

BACKGROUND AND METHODS: We studied the effect of volume resuscitation on lung fluid balance and systemic oxygen extraction during septic shock in eight anesthetized dogs. Sepsis was induced using a 2-hr continuous infusion of Escherichia coli endotoxin at 0.25 micrograms/min.kg. Relationships between oxygen uptake (VO2) and oxygen supply (DO2) were performed acutely during stepwise controlled decrements in cardiac output by progressive inflation of an intracardiac balloon. At each stage, DO2 and corresponding VO2 were measured independently and the individual critical DO2 level was referred to as the point below which the relationship held. The slope of such a constructed relationship was defined as the maximal oxygen extraction ratio. Lung fluid balance was assessed by measurements of extravascular lung water. All values were studied at baseline, after endotoxin insult, and after reversing hypotension by a 10% dextran infusion. RESULTS: Endotoxin infusion led to a shock state that associated hypotension (from 135 to 63 mm Hg) with increases in blood lactate (from 0.53 to 3.9 mmol/L). The mean critical DO2 and maximal oxygen extraction ratio were significantly altered from 7.9 to 17.8 mL/min.kg and from 0.81 to 0.38, respectively. After reversing hypotension by 28 mL/kg colloid infusion, the critical DO2 (11.4 mL/min.kg) and maximal oxygen extraction ratio (0.48) were significantly improved. However, restoration of normal values required a state of fluid overload by further dextran infusion (8 mL/kg). At the end of the fluid challenge, extravascular lung water significantly increased from 6.4 to 17.4 mL/kg. CONCLUSIONS: These data suggest that volume loading may reverse endotoxin-induced peripheral perfusion abnormalities. However, substantial pulmonary edema may occur, possibly jeopardizing the beneficial effects of fluid expansion. [less ▲]

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See detailLung function and airway inflammation monitoring after hematopoietic stem cell transplantation.
Moermans, Catherine ULg; Poulet, Christophe ULg; HENKET, Monique ULg et al

in Respiratory Medicine (2013), 107

Background Induced sputum is a non-invasive method to investigate airway inflammation, which has been used to assess pulmonary inflammatory diseases. However, this procedure has not been studied in the ... [more ▼]

Background Induced sputum is a non-invasive method to investigate airway inflammation, which has been used to assess pulmonary inflammatory diseases. However, this procedure has not been studied in the context of hematopoietic stem cell transplantation (HSCT). Methods We monitored lung function in 182 patients who underwent HSCT and measured airway inflammation by sputum induction in 80 of them. We prospectively measured FEV1, FVC, DLCO, KCO, TLC, RV, exhaled nitric oxide (FeNO) as well as sputum cell counts before and 3, 6, 12, 24 and 36 months after HSCT. Results For the whole cohort there was a progressive decrease in TLC, which was significant after 3 years (p < 0.01). By contrast, there was no change in other lung functions parameters or in FeNO. Baseline sputum analysis revealed increased neutrophil counts in patients {Median (IQR): 63% (38–79)} compared to healthy subjects matched for age {Median (IQR): 49% (17–67), p < 0.001} but there was no significant change in any type of sputum cell counts over the three years. When comparing myeloablative (MA) vs non-myeloablative (NMA) conditioning, falls in FEV1, FVC and DLCO, and rise in RV and sputum neutrophils were more pronounced over the first year of observation in those receiving MA. Conclusions There was a progressive loss in lung function after HSCT, featuring a restrictive pattern. Myeloablative conditioning was associated with early rise of sputum neutrophils and greater alteration in lung function over the first year. [less ▲]

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See detailLung inflammation and thrombogenic responses in a time course study of Csb mice exposed to ozone.
Kooter, Ingeborg M; Frederix, Kim ULg; Spronk, Henri M H et al

in Journal of Applied Toxicology (2008), 28(6), 779-87

Ozone is a well-known oxidant air pollutant, inhalation of which can result in oxidative stress, and lead to pulmonary inflammation. The aim of this study was to evaluate the time-course events after a ... [more ▼]

Ozone is a well-known oxidant air pollutant, inhalation of which can result in oxidative stress, and lead to pulmonary inflammation. The aim of this study was to evaluate the time-course events after a single ozone exposure in transcription-coupled repair defective Csb and wild type mice. Mice were exposed for 3 h to 2 ppm ozone and biological parameters related to oxidative stress and inflammation were examined in the lungs at 0, 4, 9, 24 and 48 h after exposure. In addition the procoagulant and thrombomodulin activities were explored by a combination of assays for tissue factor and thrombin generation.This study revealed a significant biological response to ozone, for both Csb and wild type mice. The onset of inflammation in Csb mice, as indicated by an increase in interleukin-6, tumor necrosis factor-alpha and total cell influx, occurred earlier compared with those seen in wild type mice. On the other hand, Csb mice showed a delayed antioxidant reaction compared with wild type mice. Both genotypes developed a procoagulant reaction characterized by a stably increased tissue factor activity and a progressive increase in thrombin generation after 2 days.These experiments have shown that ozone, a well-known toxic substance from the environment, induces not only inflammation, but also procoagulant reactions in the lungs of mice. These results have implications for understanding the systemic effects induced by oxidant air pollutants. [less ▲]

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