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See detailLa modification des marchés en cours d'exécution : théorie et pratique
Durviaux, Ann-Lawrence ULg

Conference given outside the academic context (2011)

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See detailLa modification des marchés publics en cours d'exécution et le droit européen
Durviaux, Ann-Lawrence ULg

Conference given outside the academic context (2011)

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See detailModification du champ d'application de la loi du 4 août 1992 sur le crédit hypothécaire
Biquet, Christine ULg

in Actualités législatives en droit immobilier (2001-2003) (2004)

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See detailModification du champ d'application de la loi du 4 août 1992 sur le crédit hypothécaire
Biquet, Christine ULg

in Revue Générale de Droit Civil Belge = Tijdschrift voor Belgisch Burgerlijk (2004)

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See detailLa modification du contrat de travail en droit belge et en droit français
Mortier, Aurélie ULg

in Revue de la Faculté de Droit de l'Université de Liège (2010)

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See detailModification génétique de la levure pour maîtriser la beta-oxydation: exemple de la production de lactone par Yarrowia lipolytica
Waché, Y.; Aguedo, Mario ULg; Marchal, E. et al

in Les outils biologiques dans les procédés et les techniques d'analyse...: conférences et communications scientifiques (2001, March)

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See detailModification génétique de la levure Yarrowia lipolytica pour maîtriser la β-oxydation
Waché, Y.; Aguedo, Mario ULg; LeDall, M.-T. et al

in Journal de la Société de Biologie (2001), 195(4), 459-459

Les biotechnologies font régulièrement appel à la β-oxydation pour produire des composés à haute valeur ajoutée ou dépolluer des effluents industriels. Cette voie métabolique est difficile à maîtriser car ... [more ▼]

Les biotechnologies font régulièrement appel à la β-oxydation pour produire des composés à haute valeur ajoutée ou dépolluer des effluents industriels. Cette voie métabolique est difficile à maîtriser car elle implique un nombre réduit d'enzymes pour une voie très longue. En particulier, la production d'intermédiaires réactionnels est délicate car les enzymes de la voie de reconsommation sont souvent les mêmes que celles impliquées dans la production. Ainsi, la production de γ-décalactone à partir de ricinoléate de méthyle chez Y. lipolytica implique la β-oxydation (Endrizzi et al., 1996). Cette levure est un bon modèle pour étudier le métabolisme des acides gras car elle possède cinq acyl-CoA oxydases (Aox) catalysant la première étape de la β-oxydation (Wang et al., 1999). L'effet d'une invalidation des gènes codant pour les Aox a été étudié sur la production de γ-décalactones. En fonction des Aox présentes dans les souches, différentes lactones sont produites et leur reconsommation peut être nettement ralentie. Cette étude montre qu'on peut maîtriser la β-oxydation en modifiant le matériel génétique des souches et qu'on peut ainsi améliorer les productions existantes mais aussi produire de nouvelles molécules d'intérêt. [less ▲]

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See detailModification of Chloroplast Gene Transmission in Somatic Fusion Products and Vegetative Zygotes of Chlamydomonas Reinhardi by 5-Fluorodeoxyuridine
Matagne, René-Fernand ULg; Hermesse, Marie-Paule

in Genetics (1981), 99(3-4), 371-381

Sexual crosses and somatic fusions were performed between complementing wall-less arg(-) mutant strains bearing chloroplast markers for resistance to antibiotics. The mode of chloroplast allele ... [more ▼]

Sexual crosses and somatic fusions were performed between complementing wall-less arg(-) mutant strains bearing chloroplast markers for resistance to antibiotics. The mode of chloroplast allele transmission was investigated in the diploid colonies developed from both vegetative zygotes and fusion products. Before mating or fusion, one or both of the parental strains were grown for 4 or 8 days on agar containing 5-fluorodeoxyuridine (FUdR, 0.1 to 1.0 mm), which selectively reduces the amount of chloroplast DNA in Chlamydomonas. When one parent was pregrown on FUdR, the frequency of vegetative zygotes transmitting chloroplast alleles of both parents (biparental or BP zygotes) decreased, the reduction being more drastic when the mt(-) parent was treated. Transmission was mainly uniparental maternal (UPm) or paternal (UPp) depending on whether the mt(-) or the mt(+) parent was pregrown for 8 days in the presence of 1.0 mm FUdR. Treatment of both parents led to a strong maternal transmission. In the experiments involving somatic fusion between parent 1 and parent 2 (same or opposite mt), the ratio UP(1)/UP(2), which was approximately equal to 1 in the control, decreased or increased according to whether the cells of parent 1 or 2 were pregrown on FUdR. In parallel, the frequency of BP fusion products always decreased. When both parental strains were treated with FUdR, the frequency of BP fusion products also decreased and the ratio UP(1)/UP(2) was roughly equal to 1. The effect of FUdR can be interpreted in terms of reduction of the input frequencies of parental chloroplast genomes at the time of gametic or somatic cell fusion, the bias in favor of the maternal parent being operational only in sexual crosses. [less ▲]

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See detailModification of Conductivity, Superhydrophilicity and Photocatalytic Activity of TiO2 Thin Films Through Carbon Nanotubes Doping
Léonard, Géraldine ULg; Remy, Simon; Malengreaux, Charline ULg et al

Poster (2014, July 15)

In this work, a superhydrophilic and photocatalytic material allowing to reduce the accumulation of electrostatic charges is developed. The superhydrophilicity and photocatalytic activity of TiO2 films ... [more ▼]

In this work, a superhydrophilic and photocatalytic material allowing to reduce the accumulation of electrostatic charges is developed. The superhydrophilicity and photocatalytic activity of TiO2 films provide the “easy-to-clean” property. Indeed, superhydrophilicity induces a very low contact angle between TiO2 and water leading to the formation of a water film at the surface of the material. The photocatalytic activity, responsible for the pollutant decomposition, is explained by the excitation of the semiconductor under UV light leading to the formation of electron-hole pairs. The electrical conductivity of semiconductor TiO2 is very low leading to the accumulation of electrostatic charges and so the surface becomes a dust trap. Multi-walled carbon nanotubes (MWCNTs) are electrical conductors and their introduction in TiO2 could increase the conductivity. The incorporation of MWCNTs can modify the superhydrophilicity of TiO2. The photoactivity can be improved by reducing the electron-hole recombination rate. MWCNTs play a role in electron transfer and allow to decrease the recombination of electron-hole pairs. Two sol-gel syntheses were studied in alcohol and water respectively. In the alcoholic medium, monolayer films are obtained by dip-coating on alkaline free glass and calcined at 300, 400 or 500°C. The thermal treatment allows to crystallize TiO2 in the anatase form. In the aqueous synthesis, monolayer film are obtained by dip-coating on alkaline free glass. The TiO2 shows already the anatase structure. The characterizations of the samples have confirmed the nanotube presence in the aqueous synthesis, and in the alcoholic synthesis at 300°C and 400°C but not at 500°C. The highest conductivity is obtained from the syntheses in alcohol and the calcination at 300°C. That sample does not exhibit a high photoactivity because of its poor crystallinity. The films without MWCNTs are superhydrophilic but the contact angle increase with the incorporation of MWCNTs. The superhydrophilicity is lost with MWCNTs introduction. MWCNTs increase the roughness, the thickness and the electron transfer of the TiO2 matrix. This induces an enhancement of the photoactivity under UV. The comparison between the two syntheses shows that the alcoholic synthesis (400°C) is the best for pure film. When MWCNTs are introduced, the improvement is higher in the case of aqueous synthesis than in the case of alcoholic synthesis. The aqueous synthesis leads to more active photocatalysts than the alcoholic synthesis. [less ▲]

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See detailA modification of convex approximation methods for structural optimization
Zhang, Wei-Hong; Fleury, Claude ULg

in Computers & Structures (1997), 64(1-4), 89-95

The most popular convex approximation methods used today in structural optimization are discussed in this paper: the convex linearization method (CONLIN), the method of the moving asymptotes (MMA) and the ... [more ▼]

The most popular convex approximation methods used today in structural optimization are discussed in this paper: the convex linearization method (CONLIN), the method of the moving asymptotes (MMA) and the sequential quadratic programming method (SQP). Modifications are made to enhance the reliability of the CONLIN method. In addition, a generalized MMA (GMMA) is established. However, in view of practical difficulties of evaluating second-order derivatives, a fitting scheme is proposed in this work to adjust the convexity of the approximation based on the available function value at the preceding design iteration. Numerical results show that this simple scheme is efficient in our applications. [less ▲]

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See detailModification of diet in renal disease versus chronic kidney disease epidemiology collaboration equation to estimate glomerular filtration rate in obese patients
BOUQUEGNEAU, Antoine ULg; Vidal-Petiot, Emanuelle; Vrtovsnik, François et al

in Nephrology Dialysis Transplantation (2013), 28(4), 122-130

Background Obesity is a recognized risk factor for both the development and progression of chronic kidney disease (CKD). Accurate estimation of glomerular filtration rate (GFR) is thus important in these ... [more ▼]

Background Obesity is a recognized risk factor for both the development and progression of chronic kidney disease (CKD). Accurate estimation of glomerular filtration rate (GFR) is thus important in these patients. We tested the performances of two creatinine-based GFR estimates, the Modification of Diet in Renal Disease (MDRD) and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations, in an obese population. Methods Patients with body mass index (BMI) > 30 kg/m2 were included. The reference method for measured GFR (mGFR) was 51Cr-EDTA (single-injection method, two blood samples at 120 and 240 min). Both indexed and non-indexed results were considered. Serum creatinine was measured using the IDMS-traceable compensated Jaffe method. Mean bias (eGFR–mGFR), precision (SD around the bias) and accuracy within 30% (percentage of estimations within 30% of mGFR) were calculated for both equations. Results The population included 366 patients (185 women) from two different areas. Mean age was 55 ± 14 years, and mean BMI was 36 ± 7 kg/m2. Mean mGFR was 56 ± 26 mL/min/1.73 m2 (71 ± 35 mL/min without indexation). In the total population, mean bias was +1.9 ± 14.3 and +4.6 ± 14.7 mL/min/1.73 m2 (P < 0.05), and accuracy 30% was 80 and 76% for the MDRD and CKD-EPI equations (P < 0.05), respectively. In patients with mGFR > 60 mL/min/1.73 m2, mean bias was +4.6 ± 18.4 and +9.3 ± 17.2 mL/min/1.73 m2 (P < 0.05), and accuracy 30% was 81 and 79% (NS) for the MDRD and CKD-EPI equations, respectively. Conclusions The CKD-EPI equation did not outperform the MDRD study equation in this population of obese patients [less ▲]

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See detailModification of hormonal secretion in macroprolactinoma on treatment
VROONEN, Laurent ULg; Rostomyan, Liliya ULg; Potorac, Iulia ULg et al

in 23rd meeting of the Belgian Endocrine Society - Abstract book (2013, October 19)

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See detailModification of immunoreactive EGF receptor after acute tubular necrosis induced by tobramycin or cisplatin
Leonard, I.; Zanen, J.; Nonclercq, D. et al

in Renal Failure (1994), 16(5), 583-608

Acute tubular necrosis induced by aminoglycoside antibiotics and various other nephrotoxins is followed by a regenerative process which leads to the restoration of damaged tubules. Several lines of ... [more ▼]

Acute tubular necrosis induced by aminoglycoside antibiotics and various other nephrotoxins is followed by a regenerative process which leads to the restoration of damaged tubules. Several lines of evidence indicate that tubular regeneration is mediated by polypeptide growth factors such as epidermal growth factor (EGF). Previous studies devoted to cisplatin nephrotoxicity have shown that this agent causes tubular cystic degeneration possibly related to an impairment of renal tissue repair. Thus, we examined on a comparative basis the time course of the regenerative response subsequent to tubular damage induced by tobramycin or cisplatin, particular attention being paid to renal EGF and its receptor. Female Sprague-Dawley rats (160-180 g body weight) were treated during 4 consecutive days with daily doses of 200 mg/kg tobramycin i.p. (BID) or 2 mg/kg cisplatin (once a day). Sham-treated rats were given 0.9% NaCl i.p. following the same protocol. Groups of experimental animals (n = 5-10) were terminated at increasing time intervals (1, 4, 7, 14, 21, 60 days) after cessation of treatment. One hour prior to sacrifice, each individual received i.p. 200 mg/kg 5-bromo-2'-deoxyuridine (BrdU) for the immunohistochemical demonstration of cell proliferation. Blood was collected at the time of sacrifice in order to assess glomerular filtration rate by measuring serum creatinine and BUN levels. Kidneys were analyzed with respect to total EGF determined by RIA in renal tissue homogenates, and soluble EGF was assayed in extracts prepared by centrifugation. Renal tissue was processed for the immunohistochemical detection of S-phase cells, of EGF, of EGF receptors, and of the intermediate filament vimentin, the latter being used as a marker of epithelium dedifferentiation. In absence of nephrotoxic alterations, EGF was immunolocalized in distal tubules, whereas EGF receptor immunostaining was seen in proximal tubules cells. Vimentin immunostaining was confined to glomeruli and blood vessels. Tobramycin and cisplatin caused acute tubular necrosis in proximal convoluted tubules and proximal straight tubules, respectively. Tissue damage was accompanied by renal dysfunction reflected by an elevation of serum creatinine and BUN levels. Tubular necrosis was followed by a proliferative response indicative of tubular regeneration. Regenerative hyperplasia was associated with a reduction of total immunoreactive EGF due to a decrease of tissue-bound proEGF. Tubules undergoing regenerative repair were characterized by a disappearance of EGF receptors and the presence of immunoreactive vimentin. In tobramycin-treated rats, renal dysfunction lasted for 4-7 days and was fully reversible, as indicated by the return of serum markers to normal values. [less ▲]

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See detailModification of the interfacial properties of whey by enzymatic hydrolysis of the residual fat.
Blecker, Christophe ULg; Cerne, V.; Paquot, Michel ULg et al

in Lorient, D.; Dickinson, E. (Eds.) Food Macromolecules and Colloids. (1995)

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See detailModification of the polycarbonate/poly(vinylidene Fluoride) interface by poly(methyl methacrylate). Effect on the interfacial adhesion and interfacial tension
Moussaif, Noureddin; Jérôme, Robert ULg

in Macromolecular Symposia (1999), 139

Polycarbonate (PC) and poly(vinylidene fluoride) (PVDF) are two immiscible polymers which form two-phase blends with weak interfacial adhesion and high interfacial tension This situation may be changed by ... [more ▼]

Polycarbonate (PC) and poly(vinylidene fluoride) (PVDF) are two immiscible polymers which form two-phase blends with weak interfacial adhesion and high interfacial tension This situation may be changed by the addition of poly(methyl methacrylate) (PMMA), which concentrates preferably in the PVDF-rich phase, but also at the PVDF/PC interface. The interfacial activity of PMMA was estimated by the measurement of the interfacial adhesion and interfacial tension in relation to the PMMA content in the PVDF/PC blends. The interfacial adhesion between PC and homogeneous PVDF/PMMA blends of various compositions was measured by the dual cantilever beam technique The imbedded fiber retraction method was used for the measurement of the interfacial tension. A very beneficial effect was observed when PVDF was premixed with PMMA amounts increasing up to ca 35 wt-%., Beyond that content, the improvement tends to level off. [less ▲]

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See detailModification of the Selected Method for the Determination of Serum Iron. Substitution of Bathophenanthroline by Ferene S
Charlier, Corinne ULg; Plomteux, Guy ULg; Vernet, M. et al

in Annales de Biologie Clinique (1992), 50(3), 191-202

The previously selected method (1977) for the measurement of iron in human serum has been modified by the working group on Iron and Iron-Transport Proteins (Societe Francaise de Biologie Clinique). Ferene ... [more ▼]

The previously selected method (1977) for the measurement of iron in human serum has been modified by the working group on Iron and Iron-Transport Proteins (Societe Francaise de Biologie Clinique). Ferene S is used as the chromogen, it is more sensitive and cheaper than bathophenanthroline. The sample size has been reduced from 2 to 0.5 ml. No interference could be shown with high concentrations of bilirubin, copper or hemoglobin. [less ▲]

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See detailModification of the thermoresistance to spray-drying of a cold-adapted subtilisin by genetic engineering
Bare, G.; Diakiese, A.; Zgoulli, S. et al

Poster (1998, May 08)

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