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See detailLe multiculturalisme et les démocraties libérales
Martiniello, Marco ULg

Scientific conference (2005, November 18)

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See detailLe multiculturalisme: entre pluralisme culturel et affirmation identitaire
Delruelle, Edouard ULg

in Les minorités : un défi pour les Etats. Actes du colloque international (12 et 13 mai 2011) (2012)

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See detailMultidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.
Wu, Shuangding; Vossius, Sofie ULg; Rahmouni, Souad ULg et al

in Journal of Medicinal Chemistry (2009), 52(21), 6716-23

Loss of VHR phosphatase causes cell cycle arrest in HeLa carcinoma cells, suggesting that VHR inhibition may be a useful approach to halt the growth of cancer cells. We recently reported that VHR is ... [more ▼]

Loss of VHR phosphatase causes cell cycle arrest in HeLa carcinoma cells, suggesting that VHR inhibition may be a useful approach to halt the growth of cancer cells. We recently reported that VHR is upregulated in several cervix cancer cell lines as well as in carcinomas of the uterine cervix. Here we report the development of multidentate small-molecule inhibitors of VHR that inhibit its enzymatic activity at nanomolar concentrations and exhibit antiproliferative effects on cervix cancer cells. Chemical library screening was used to identify hit compounds, which were further prioritized in profiling and kinetic experiments. SAR analysis was applied in the search for analogs with improved potency and selectivity, resulting in the discovery of novel inhibitors that are able to interact with both the phosphate-binding pocket and several distinct hydrophobic regions within VHR’s active site. This multidentate binding mode was confirmed by X-ray crystallography. The inhibitors decreased the proliferation of cervix cancer cells, while growth of primary normal keratinocytes was not affected. These compounds may be a starting point to develop drugs for the treatment of cervical cancer. [less ▲]

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See detailMultidimensional analysis of social identities
Jacquemain, Marc ULg; Vandekeere, Michel

Conference (1990, January)

All the CLEO's researches based on opinion polls have showed that feeling of belgonging to Belgium and Wallony go hand in hand rather tha being substitute. The use of tools like multimensional scaling ... [more ▼]

All the CLEO's researches based on opinion polls have showed that feeling of belgonging to Belgium and Wallony go hand in hand rather tha being substitute. The use of tools like multimensional scaling help to calculate "proximities" between all feelings of belonging and help design a global map of identities. [less ▲]

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See detailMultidimensional extension of the Morse-Hedlund theorem
Durand, Fabien; Rigo, Michel ULg

in European Journal of Combinatorics (2013), 34

Nivat's conjecture is about the link between the pure periodicity of a subset M of Z^2, i.e., invariance under translation by a fixed vector, and some upper bound on the function counting the number of ... [more ▼]

Nivat's conjecture is about the link between the pure periodicity of a subset M of Z^2, i.e., invariance under translation by a fixed vector, and some upper bound on the function counting the number of different rectangular blocks occurring in $M$. Attempts to solve this conjecture have been considered during the last fifteen years. Let d>1. A legitimate extension to a multidimensional setting of the notion of periodicity is to consider sets of Z^d definable by a first order formula in the Presburger arithmetic <Z;<,+>. With this latter notion and using a powerful criterion due to Muchnik, we solve an analogue of Nivat's conjecture and characterize sets of Z^d definable in <Z;<,+> in terms of some functions counting recurrent blocks, that is, blocks occurring infinitely often. [less ▲]

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See detailMULTIDIMENSIONAL FLOW MODELLING TO GUIDE HYDROMORPHOLOGICAL RESTORATION OF AN ALPINE RIVER
Rulot, François ULg; Detrembleur, Sylvain; Archambeau, Pierre ULg et al

in Proceedings of the 9th International Symposium on Ecohydraulics 2012 (2012)

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See detailMultidimensional fluctuation, pseudo-guessing and carelessness IRT person parameters with polytomous item response models
Raîche, Gilles; Magis, David ULg; Béland, Sébastien

Conference (2010, July)

Frequently, candidates at aptitude multiple choice test miss attention, motivation or preparation and show underachievement or overachievement. Similarly, at surveys respondents show frequently misfitting ... [more ▼]

Frequently, candidates at aptitude multiple choice test miss attention, motivation or preparation and show underachievement or overachievement. Similarly, at surveys respondents show frequently misfitting patterns of responses. Their result does not correspond any more to their true aptitude or attitude, an inappropriate response pattern being obtained. New multidimensional models specific to polytomous responses circumvent these situations and diminish considerably the associated person bias. Multidimensional polytomous item response models adding new person parameters to the trait of the candidate are proposed. In the spirit of previous Raiche’s dichotomous responses IRT propositions, like the discrimination and don’t know item parameters, these models offer fluctuation and don’t know person parameters. Estimation methods, results from simulation showing the efficacy of these models and recommendations for the design of testing situations will be presented. [less ▲]

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See detailMultidimensional fluctuation, pseudo-guessing and carelness IRT person parameters models
Raîche, Gilles; Magis, David ULg; Blais, Jean-Guy

Conference (2009, July)

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See detailMultidimensional GCxGC Fingerprinting for Environmental and Biological Forensics
Patterson Jr; Sandau; Focant, Jean-François ULg

Conference (2011, July)

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See detailMultidimensional generalized automatic sequences and shape-symmetric morphic words
Charlier, Emilie ULg; Kärki, Tomi; Rigo, Michel ULg

in Proceedings of AutoMathA (2009)

An infinite word is S-automatic if, for all n ≥ 0, its (n + 1)st letter is the output of a deterministic automaton fed with the representation of n in the considered numeration system S. In this paper, we ... [more ▼]

An infinite word is S-automatic if, for all n ≥ 0, its (n + 1)st letter is the output of a deterministic automaton fed with the representation of n in the considered numeration system S. In this paper, we consider an analogous definition in a multidimensional setting and study the relationship with the shape-symmetric infinite words as introduced by Arnaud Maes. Precisely, for d ≥ 2, we show that a multidimensional infinite word x : N^d → Σ over a finite alphabet Σ is S-automatic for some abstract numeration system S built on a regular language containing the empty word if and only if x is the image by a coding of a shape-symmetric infinite word. [less ▲]

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See detailMultidimensional generalized automatic sequences and shape-symmetric morphic words
Charlier, Emilie ULg; Kärki, Tomi; Rigo, Michel ULg

in Discrete Mathematics (2010), 310

An infinite word is S-automatic if, for all n>=0, its (n+1)st letter is the output of a deterministic automaton fed with the representation of n in the numeration system S. In this paper, we consider an ... [more ▼]

An infinite word is S-automatic if, for all n>=0, its (n+1)st letter is the output of a deterministic automaton fed with the representation of n in the numeration system S. In this paper, we consider an analogous definition in a multidimensional setting and study its relation to the shapesymmetric infinite words introduced by Arnaud Maes. More precisely, for d>1, we show that a multidimensional infinite word x over a finite alphabet is S-automatic for some abstract numeration system S built on a regular language containing the empty word if and only if x is the image by a coding of a shape-symmetric infinite word. [less ▲]

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See detailMultidimensional growth measurements of abdominal aortic aneurysms.
Martufi, Giampaolo; Auer, Martin; Roy, Joy et al

in Journal of vascular surgery (2013), 58(3), 748-55

BACKGROUND: Monitoring the expansion of abdominal aortic aneurysms (AAAs) is critical to avoid aneurysm rupture in surveillance programs, for instance. However, measuring the change of the maximum ... [more ▼]

BACKGROUND: Monitoring the expansion of abdominal aortic aneurysms (AAAs) is critical to avoid aneurysm rupture in surveillance programs, for instance. However, measuring the change of the maximum diameter over time can only provide limited information about AAA expansion. Specifically, regions of fast diameter growth may be missed, axial growth cannot be quantified, and shape changes of potential interest for decisions related to endovascular aneurysm repair cannot be captured. METHODS: This study used multiple centerline-based diameter measurements between the renal arteries and the aortic bifurcation to quantify AAA growth in 51 patients from computed tomography angiography (CTA) data. Criteria for inclusion were at least 1 year of patient follow-up and the availability of at least two sufficiently high-resolution CTA scans that allowed an accurate three-dimensional reconstruction. Consequently, 124 CTA scans were systematically analyzed by using A4clinics diagnostic software (VASCOPS GmbH, Graz, Austria), and aneurysm growth was monitored at 100 cross-sections perpendicular to the centerline. RESULTS: Monitoring diameter development over the entire aneurysm revealed the sites of the fastest diameter growth, quantified the axial growth, and showed the evolution of the neck morphology over time. Monitoring the development of an aneurysm's maximum diameter or its volume over time can assess the mean diameter growth (r = 0.69, r = 0.77) but not the maximum diameter growth (r = 0.43, r = 0.34). The diameter growth measured at the site of maximum expansion was ~16%/y, almost four times larger than the mean diameter expansion of 4.4%/y. The sites at which the maximum diameter growth was recorded did not coincide with the position of the maximum baseline diameter (rho = 0 .12; P = .31). The overall aneurysm sac length increased from 84 to 89 mm during the follow-up (P < .001), which relates to the median longitudinal growth of 3.5%/y. The neck length shortened, on average, by 6.2% per year and was accompanied by a slight increase in neck angulation. CONCLUSIONS: Neither maximum diameter nor volume measurements over time are able to measure the fastest diameter growth of the aneurysm sac. Consequently, expansion-related wall weakening might be inappropriately reflected by this type of surveillance data. In contrast, localized spots of fast diameter growth can be detected through multiple centerline-based diameter measurements over the entire aneurysm sac. This information might further reinforce the quality of aneurysm surveillance programs. [less ▲]

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See detailMultidimensionnalité de la précarité
Gavray, Claire ULg; Ruyters, Christine

Report (2001)

Ce livre consiste en un état des lieux de la cohésion économique en -et par la- Région Wallonne. Il comporte un volet statistique (sur les personnes et les ménages en matière d'emploi, de famille, de ... [more ▼]

Ce livre consiste en un état des lieux de la cohésion économique en -et par la- Région Wallonne. Il comporte un volet statistique (sur les personnes et les ménages en matière d'emploi, de famille, de santé et de sécurité d'existence) , un volet descriptif d'actions menées et un volet 'analyses et recommandations'. [less ▲]

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See detailMultidimensionnalité des facteurs de précarité - Articulation des risques et fragilités d'existence
Gavray, Claire ULg; Ruyters, Christine

in Rapport sur la cohésion sociale en région wallonne - volet statistique (2007)

Ce livre donne pour la deuxième fois un état des lieux de la cohésion sociale en Wallonnie sur base d'indicateurs socio-économiques. Il comporte des données en matière d'emploi, de famille, de revenus, de ... [more ▼]

Ce livre donne pour la deuxième fois un état des lieux de la cohésion sociale en Wallonnie sur base d'indicateurs socio-économiques. Il comporte des données en matière d'emploi, de famille, de revenus, de santé, de sécurité d'existence ...issues de diverses enquêtes et banques de données. [less ▲]

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See detailMultidisciplinary and Evidence-based Method for Prioritizing Diseases of Food-producing Animals and Zoonoses
Humblet, Marie-France ULg; Vandeputte, Sébastien ULg; Albert, Adelin ULg et al

in Emerging Infectious Diseases (2012), 18(4),

To prioritize 100 animal diseases and zoonoses in Europe, we used a multicriteria decision-making procedure based on opinions of experts and evidence-based data. Forty international experts performed ... [more ▼]

To prioritize 100 animal diseases and zoonoses in Europe, we used a multicriteria decision-making procedure based on opinions of experts and evidence-based data. Forty international experts performed intracategory and intercategory weighting of 57 prioritization criteria. Two methods (deterministic with mean of each weight and probabilistic with distribution functions of weights by using Monte Carlo simulation) were used to calculate a score for each disease. Consecutive ranking was established. Few differences were observed between each method. Compared with previous prioritization methods, our procedure is evidence based, includes a range of fields and criteria while considering uncertainty, and will be useful for analyzing diseases that affect public health [less ▲]

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See detailMultidisciplinary approach in two patients with multiple peroxysomal function deficiency
Misson, Jean-Paul ULg; Evrard, Ph; Verellen, G. et al

in Peroxisomes and their metabolites in cellular functions (1985, August)

Detailed reference viewed: 6 (0 ULg)