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See detailAre The Fusion Processes Involved In Birth, Life And Death Of The Cell Depending On Tilted Insertion Of Peptides Into Membranes?
Peuvot, J.; Schanck, A.; Lins, Laurence ULg et al

in Journal of Theoretical Biology (1999), 198(2), 173-81

Various peptide segments have been modeled as asymmetric amphipathic alpha-helices. Theoretical calculations have shown that they insert obliquely into model membranes. They have been named "tilted ... [more ▼]

Various peptide segments have been modeled as asymmetric amphipathic alpha-helices. Theoretical calculations have shown that they insert obliquely into model membranes. They have been named "tilted peptides". Molecular modeling results reported here also evidence the presence of tilted peptides in ADM-1 protein of Caenorhabditis elegans that may be involved in fusion events, in meltrin alpha, a protein implicated in myoblast fusion, in hemagglutinin of influenza virus, in the E2 glycoprotein of rubella virus, in the S protein of hepatitis B virus, in a subdomain of Ebola virus and in the malaria CS protein. Experimental results have indicated that tilted peptide fragments may be involved in cellular life events like sperm-egg fecondation, muscle development, protein translocation through signal sequences and cellular death caused by viral infection or parasite infestation. We speculate that membrane destabilization by these tilted peptides may be an important common step in life processes involving fusion phenomena. [less ▲]

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See detailAre the IKKs and IKK-related kinases TBK1 and IKK-ε similarly activated ?
Chau, Tieu-Lan ULg; Gioia, Romain ULg; Gatot, Jean-Stéphane et al

in Trends in Biochemical Sciences - Regular Edition (2008), 33

The IKKs, IKKa and IKKb, and the IKK-related kinases TBK1 and IKKe, play essential roles in innate immunity through signal-induced activation of NF-κB and IRF3/7, respectively. Although the signaling ... [more ▼]

The IKKs, IKKa and IKKb, and the IKK-related kinases TBK1 and IKKe, play essential roles in innate immunity through signal-induced activation of NF-κB and IRF3/7, respectively. Although the signaling events within these pathways have been extensively studied, the mechanisms of IKK and IKK-related complex assembly and activation remain poorly defined. Recent data provide insight into the requirement for scaffold proteins in complex assembly; NEMO coordinates some IKK complexes, whereas TANK, NAP1 or SINTBAD assemble TBK1 and IKKe complexes. The different scaffold proteins undergo similar post-translational modifications, including phosphorylation and non-degradative polyubiquitylation. Moreover, increasing evidence suggests that distinct scaffold proteins assemble IKK and potentially TBK1 and IKKε sub-complexes in a stimulus-specific manner, which might be a mechanism to achieve specificity. [less ▲]

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See detailAre the interactions between neurodegenerative proteins and polymeric surfaces related to the hydrophilic and hydrophobic balance ?
Vrlinic; Debarnot, Dominique; Legeay, Gilbert et al

in Macromolecular Bioscience (2012), In press

In press

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See detailAre the interactions between recombinant prion protein and polymeric surfaces related to the hydrophilic and hydrophobic balance ?
Vrlinic, Tjasa; Debarnot, Dominique; Legeay, Gilbert et al

in Macromolecular Bioscience (2012), In press

In press

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See detailAre there arguments allowing to propose that polyamines are preventive agents of food allergy
Dandrifosse, Guy ULg; Peulen, Olivier ULg; El Khefif, N et al

Conference (1998, November)

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See detailAre there arguments suggesting that polyamines are preventive agents of food allergy ?
Dandrifosse, Guy ULg; Peulen, Olivier ULg; Khefif, N. El et al

in Proceeding of the COST 917 Meeting in Malaga (2000)

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See detailAre there arguments suggesting that polyamines are preventive agents of food allergy?
Dandrifosse, Guy ULg; Peulen, Olivier ULg; El Khefif, Nor Eddine et al

in Morgan, D.; White, A.; Sanchez-Jimenez, F. (Eds.) et al COST 917 Biologically active amines in food. Volume IV (2000)

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See detailAre There Common Trends in European Stock Markets?
Corhay, Albert ULg; Tourani Rad, Alireza; Urbain, Jean-Pierre

E-print/Working paper (1992)

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See detailAre there oscillations in the baryon / meson ratio?
Cudell, Jean-René ULg; Dienes, Keith R

in Physical Review Letters (1992), 69

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See detailAre there specific models of social enterprise in Eastern Asia?
Defourny, Jacques ULg; Kuan, Yu Yuan

in Social Enterprise Journal (2011), 7(1), 5-8

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See detailAre time-based and event-based prospective memory affected by normal aging in the same way ?
Bastin, Christine ULg; Meulemans, Thierry ULg

in Current Psychology Letters: Behavious, Brain and Cognition (2002), 7

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See detailAre WC9 Wolf-Rayet stars in colliding-wind binaries?
Williams, P. M.; van der Hucht, K. A.; Rauw, Grégor ULg

in Massive Stars and High-Energy Emission in OB Associations (2005, November 01)

We present results from a spectroscopic search for massive companions to dust-making Galactic WC9 stars as a step to testing the paradigm that dust formation in these systems requires colliding winds to ... [more ▼]

We present results from a spectroscopic search for massive companions to dust-making Galactic WC9 stars as a step to testing the paradigm that dust formation in these systems requires colliding winds to produce over densities. We find evidence for OB companions to the WC9 stars WR 59 and WR 65, but not WR 121 or WR 117. We identify lines of N III-V and possibly N II in the spectrum of WR 88, one of the few Galactic WC9 stars which do not make circumstellar dust, and suggest that WR 88 is a transitional WN--WC9 object and less evolved than the other WC9 stars. On the other hand, the possible identification of a strong emission line at 4176 in the spectrum of WR 117 with Ne I suggests that this star is more evolved than other WC9 stars studied. [less ▲]

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See detailAre we all vitamin-D deficient?
CAVALIER, Etienne ULg

in Correspondances en MHDN (2011), 15(6), 191-195

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See detailAre we close to decyphering the timer's enigma ?
Richelle, Marc ULg; Lejeune, Helga ULg

in Current Psychology of Cognition [=CPC] = Cahiers de Psychologie Cognitive [=CPC] (1998), 17(4-5), 867-879

Among the theoretical models, Gibbon and Chruch's temporal information processing model is by far the most popular explanatory device in the domain of animal timing, and timing recorded using the peak ... [more ▼]

Among the theoretical models, Gibbon and Chruch's temporal information processing model is by far the most popular explanatory device in the domain of animal timing, and timing recorded using the peak procedure is considered to reflect pure cognitive time. Neuropharmacological breakthroughs suggest that diferent neurotransmitter systems subserve different functions or stages, as specified by the temporal information proccessing model. Cerebral activations correlated to timing performance have been described in humans. however, several questions remain unanswered, particularly those regarding the specificity of the neutral and biochemical correlates of timing performance. At the behavioral level, the dynamic aspects of timing, as well as timing patterns which cannot be explained within the framework of existing models, deserve a renewal of interest. [less ▲]

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See detailAre we equal in death?
Laureys, Steven ULg; Fins, Joseph J.

in Neurology (2008), 70

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See detailAre we giving biologics too much time? When should we stop treatment?
Louis, Edouard ULg; Reenaers, Catherine ULg; Belaiche, Jacques ULg

in World Journal of Gastroenterology (2008), 14

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See detail"'Are you blind, Lord Thomas, or can't you very well see?': An Interpretation of Death in the Newfoundland Classical Ballads"
Peere, Isabelle ULg

in Laforte,, Conrad (Ed.) Ballades et chansons folkloriques (1989)

A talerole analysis of the Newfoundland Child ballad corpus dealing with death, suggesting how death can be avoided and overcome, or these songs' concern with life as 'strategies for survival'.

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