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See detailAre the complications of arteriovenous fistulas associated with an abnormal Ankle-Brachial Index in hemodialysis patients?
Xhignesse, Patricia ULg; Saint-Remy, Annie ULg; Dubois, Bernard ULg et al

in Acta Clinica Belgica (2010), 65(1), 65

The peripheral artery disease is frequent among patients undergoing hemodialysis much more than in the general population. The ankle-brachial index (AB!) is a potent tool to screen this pathology. We ... [more ▼]

The peripheral artery disease is frequent among patients undergoing hemodialysis much more than in the general population. The ankle-brachial index (AB!) is a potent tool to screen this pathology. We analysed the relationship between ABI abnormal values and arteriovenous fistulas (AVF) complications such as stenosis and thrombosis among chronically hemodialysis pat ients (HD). [less ▲]

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See detailAre the creatinine-based equations accurate to estimate glomerular filtration rate in african american populations ?
DELANAYE, Pierre ULg; MARIAT, Christophe; MAILLARD, Nicolas et al

in Clinical Journal of the American Society of Nephrology (2011), 6

Regarding the high prevalence of African American patients with ESRD, it is important to estimate the prevalence of early stages of chronic kidney disease in this specific population. Because serum ... [more ▼]

Regarding the high prevalence of African American patients with ESRD, it is important to estimate the prevalence of early stages of chronic kidney disease in this specific population. Because serum creatinine concentration is dependent on muscular mass, an ethnic factor has to be applied to creatinine-based equations. Such ethnic factors have been proposed in the Modification of Diet in Renal Disease (MDRD) study equation and in the more recent Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations. This review analyzes how these correction factors have been developed and how they have, or have not, been validated in external populations. It will be demonstrated that the African American factor in the MDRD study equation is accurate in African American chronic kidney disease (CKD) patients. However, it will be shown that this factor is probably too high for subjects with a GFR of >60 ml/min per 1.73 m2, leading to an underestimation of the prevalence of CKD in the global African American population. It will also be confirmed that this ethnic factor is not accurate in African (non-American) subjects. Lastly, the lack of true external validation of the new CKD-EPI equations will be discussed. Additional trials seem necessary in American African and African populations to better estimate GFR and apprehend the true prevalence of CKD in this population with a high renal risk. [less ▲]

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See detailAre The Fusion Processes Involved In Birth, Life And Death Of The Cell Depending On Tilted Insertion Of Peptides Into Membranes?
Peuvot, J.; Schanck, A.; Lins, Laurence ULg et al

in Journal of Theoretical Biology (1999), 198(2), 173-81

Various peptide segments have been modeled as asymmetric amphipathic alpha-helices. Theoretical calculations have shown that they insert obliquely into model membranes. They have been named "tilted ... [more ▼]

Various peptide segments have been modeled as asymmetric amphipathic alpha-helices. Theoretical calculations have shown that they insert obliquely into model membranes. They have been named "tilted peptides". Molecular modeling results reported here also evidence the presence of tilted peptides in ADM-1 protein of Caenorhabditis elegans that may be involved in fusion events, in meltrin alpha, a protein implicated in myoblast fusion, in hemagglutinin of influenza virus, in the E2 glycoprotein of rubella virus, in the S protein of hepatitis B virus, in a subdomain of Ebola virus and in the malaria CS protein. Experimental results have indicated that tilted peptide fragments may be involved in cellular life events like sperm-egg fecondation, muscle development, protein translocation through signal sequences and cellular death caused by viral infection or parasite infestation. We speculate that membrane destabilization by these tilted peptides may be an important common step in life processes involving fusion phenomena. [less ▲]

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See detailAre the IKKs and IKK-related kinases TBK1 and IKK-ε similarly activated ?
Chau, Tieu-Lan ULg; Gioia, Romain ULg; Gatot, Jean-Stéphane et al

in Trends in Biochemical Sciences - Regular Edition (2008), 33

The IKKs, IKKa and IKKb, and the IKK-related kinases TBK1 and IKKe, play essential roles in innate immunity through signal-induced activation of NF-κB and IRF3/7, respectively. Although the signaling ... [more ▼]

The IKKs, IKKa and IKKb, and the IKK-related kinases TBK1 and IKKe, play essential roles in innate immunity through signal-induced activation of NF-κB and IRF3/7, respectively. Although the signaling events within these pathways have been extensively studied, the mechanisms of IKK and IKK-related complex assembly and activation remain poorly defined. Recent data provide insight into the requirement for scaffold proteins in complex assembly; NEMO coordinates some IKK complexes, whereas TANK, NAP1 or SINTBAD assemble TBK1 and IKKe complexes. The different scaffold proteins undergo similar post-translational modifications, including phosphorylation and non-degradative polyubiquitylation. Moreover, increasing evidence suggests that distinct scaffold proteins assemble IKK and potentially TBK1 and IKKε sub-complexes in a stimulus-specific manner, which might be a mechanism to achieve specificity. [less ▲]

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See detailAre the interactions between neurodegenerative proteins and polymeric surfaces related to the hydrophilic and hydrophobic balance ?
Vrlinic; Debarnot, Dominique; Legeay, Gilbert et al

in Macromolecular Bioscience (2012), In press

In press

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See detailAre the interactions between recombinant prion protein and polymeric surfaces related to the hydrophilic and hydrophobic balance ?
Vrlinic, Tjasa; Debarnot, Dominique; Legeay, Gilbert et al

in Macromolecular Bioscience (2012), In press

In press

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See detailAre there arguments allowing to propose that polyamines are preventive agents of food allergy
Dandrifosse, Guy ULg; Peulen, Olivier ULg; El Khefif, N et al

Conference (1998, November)

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See detailAre there arguments suggesting that polyamines are preventive agents of food allergy ?
Dandrifosse, Guy ULg; Peulen, Olivier ULg; Khefif, N. El et al

in Proceeding of the COST 917 Meeting in Malaga (2000)

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See detailAre there arguments suggesting that polyamines are preventive agents of food allergy?
Dandrifosse, Guy ULg; Peulen, Olivier ULg; El Khefif, Nor Eddine et al

in Morgan, D.; White, A.; Sanchez-Jimenez, F. (Eds.) et al COST 917 Biologically active amines in food. Volume IV (2000)

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See detailAre There Common Trends in European Stock Markets?
Corhay, Albert ULg; Tourani Rad, Alireza; Urbain, Jean-Pierre

E-print/Working paper (1992)

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See detailAre there oscillations in the baryon / meson ratio?
Cudell, Jean-René ULg; Dienes, Keith R

in Physical Review Letters (1992), 69

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See detailAre there specific models of social enterprise in Eastern Asia?
Defourny, Jacques ULg; Kuan, Yu Yuan

in Social Enterprise Journal (2011), 7(1), 5-8

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See detailAre time-based and event-based prospective memory affected by normal aging in the same way ?
Bastin, Christine ULg; Meulemans, Thierry ULg

in Current Psychology Letters: Behavious, Brain and Cognition (2002), 7

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See detailAre WC9 Wolf-Rayet stars in colliding-wind binaries?
Williams, P. M.; van der Hucht, K. A.; Rauw, Grégor ULg

in Massive Stars and High-Energy Emission in OB Associations (2005, November 01)

We present results from a spectroscopic search for massive companions to dust-making Galactic WC9 stars as a step to testing the paradigm that dust formation in these systems requires colliding winds to ... [more ▼]

We present results from a spectroscopic search for massive companions to dust-making Galactic WC9 stars as a step to testing the paradigm that dust formation in these systems requires colliding winds to produce over densities. We find evidence for OB companions to the WC9 stars WR 59 and WR 65, but not WR 121 or WR 117. We identify lines of N III-V and possibly N II in the spectrum of WR 88, one of the few Galactic WC9 stars which do not make circumstellar dust, and suggest that WR 88 is a transitional WN--WC9 object and less evolved than the other WC9 stars. On the other hand, the possible identification of a strong emission line at 4176 in the spectrum of WR 117 with Ne I suggests that this star is more evolved than other WC9 stars studied. [less ▲]

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See detailAre we all vitamin-D deficient?
CAVALIER, Etienne ULg

in Correspondances en MHDN (2011), 15(6), 191-195

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See detailAre we close to decyphering the timer's enigma ?
Richelle, Marc ULg; Lejeune, Helga ULg

in Current Psychology of Cognition [=CPC] = Cahiers de Psychologie Cognitive [=CPC] (1998), 17(4-5), 867-879

Among the theoretical models, Gibbon and Chruch's temporal information processing model is by far the most popular explanatory device in the domain of animal timing, and timing recorded using the peak ... [more ▼]

Among the theoretical models, Gibbon and Chruch's temporal information processing model is by far the most popular explanatory device in the domain of animal timing, and timing recorded using the peak procedure is considered to reflect pure cognitive time. Neuropharmacological breakthroughs suggest that diferent neurotransmitter systems subserve different functions or stages, as specified by the temporal information proccessing model. Cerebral activations correlated to timing performance have been described in humans. however, several questions remain unanswered, particularly those regarding the specificity of the neutral and biochemical correlates of timing performance. At the behavioral level, the dynamic aspects of timing, as well as timing patterns which cannot be explained within the framework of existing models, deserve a renewal of interest. [less ▲]

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See detailAre we equal in death?
Laureys, Steven ULg; Fins, Joseph J.

in Neurology (2008), 70

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