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See detailModification of hormonal secretion in macroprolactinoma on treatment
VROONEN, Laurent ULg; Rostomyan, Liliya ULg; Potorac, Iulia ULg et al

in 23rd meeting of the Belgian Endocrine Society - Abstract book (2013, October 19)

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See detailModification of immunoreactive EGF receptor after acute tubular necrosis induced by tobramycin or cisplatin
Leonard, I.; Zanen, J.; Nonclercq, D. et al

in Renal Failure (1994), 16(5), 583-608

Acute tubular necrosis induced by aminoglycoside antibiotics and various other nephrotoxins is followed by a regenerative process which leads to the restoration of damaged tubules. Several lines of ... [more ▼]

Acute tubular necrosis induced by aminoglycoside antibiotics and various other nephrotoxins is followed by a regenerative process which leads to the restoration of damaged tubules. Several lines of evidence indicate that tubular regeneration is mediated by polypeptide growth factors such as epidermal growth factor (EGF). Previous studies devoted to cisplatin nephrotoxicity have shown that this agent causes tubular cystic degeneration possibly related to an impairment of renal tissue repair. Thus, we examined on a comparative basis the time course of the regenerative response subsequent to tubular damage induced by tobramycin or cisplatin, particular attention being paid to renal EGF and its receptor. Female Sprague-Dawley rats (160-180 g body weight) were treated during 4 consecutive days with daily doses of 200 mg/kg tobramycin i.p. (BID) or 2 mg/kg cisplatin (once a day). Sham-treated rats were given 0.9% NaCl i.p. following the same protocol. Groups of experimental animals (n = 5-10) were terminated at increasing time intervals (1, 4, 7, 14, 21, 60 days) after cessation of treatment. One hour prior to sacrifice, each individual received i.p. 200 mg/kg 5-bromo-2'-deoxyuridine (BrdU) for the immunohistochemical demonstration of cell proliferation. Blood was collected at the time of sacrifice in order to assess glomerular filtration rate by measuring serum creatinine and BUN levels. Kidneys were analyzed with respect to total EGF determined by RIA in renal tissue homogenates, and soluble EGF was assayed in extracts prepared by centrifugation. Renal tissue was processed for the immunohistochemical detection of S-phase cells, of EGF, of EGF receptors, and of the intermediate filament vimentin, the latter being used as a marker of epithelium dedifferentiation. In absence of nephrotoxic alterations, EGF was immunolocalized in distal tubules, whereas EGF receptor immunostaining was seen in proximal tubules cells. Vimentin immunostaining was confined to glomeruli and blood vessels. Tobramycin and cisplatin caused acute tubular necrosis in proximal convoluted tubules and proximal straight tubules, respectively. Tissue damage was accompanied by renal dysfunction reflected by an elevation of serum creatinine and BUN levels. Tubular necrosis was followed by a proliferative response indicative of tubular regeneration. Regenerative hyperplasia was associated with a reduction of total immunoreactive EGF due to a decrease of tissue-bound proEGF. Tubules undergoing regenerative repair were characterized by a disappearance of EGF receptors and the presence of immunoreactive vimentin. In tobramycin-treated rats, renal dysfunction lasted for 4-7 days and was fully reversible, as indicated by the return of serum markers to normal values. [less ▲]

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See detailModification of the interfacial properties of whey by enzymatic hydrolysis of the residual fat.
Blecker, Christophe ULg; Cerne, V.; Paquot, Michel ULg et al

in Lorient, D.; Dickinson, E. (Eds.) Food Macromolecules and Colloids. (1995)

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See detailModification of the polycarbonate/poly(vinylidene Fluoride) interface by poly(methyl methacrylate). Effect on the interfacial adhesion and interfacial tension
Moussaif, Noureddin; Jérôme, Robert ULg

in Macromolecular Symposia (1999), 139

Polycarbonate (PC) and poly(vinylidene fluoride) (PVDF) are two immiscible polymers which form two-phase blends with weak interfacial adhesion and high interfacial tension This situation may be changed by ... [more ▼]

Polycarbonate (PC) and poly(vinylidene fluoride) (PVDF) are two immiscible polymers which form two-phase blends with weak interfacial adhesion and high interfacial tension This situation may be changed by the addition of poly(methyl methacrylate) (PMMA), which concentrates preferably in the PVDF-rich phase, but also at the PVDF/PC interface. The interfacial activity of PMMA was estimated by the measurement of the interfacial adhesion and interfacial tension in relation to the PMMA content in the PVDF/PC blends. The interfacial adhesion between PC and homogeneous PVDF/PMMA blends of various compositions was measured by the dual cantilever beam technique The imbedded fiber retraction method was used for the measurement of the interfacial tension. A very beneficial effect was observed when PVDF was premixed with PMMA amounts increasing up to ca 35 wt-%., Beyond that content, the improvement tends to level off. [less ▲]

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See detailModification of the Selected Method for the Determination of Serum Iron. Substitution of Bathophenanthroline by Ferene S
Charlier, Corinne ULg; Plomteux, Guy ULg; Vernet, M. et al

in Annales de Biologie Clinique (1992), 50(3), 191-202

The previously selected method (1977) for the measurement of iron in human serum has been modified by the working group on Iron and Iron-Transport Proteins (Societe Francaise de Biologie Clinique). Ferene ... [more ▼]

The previously selected method (1977) for the measurement of iron in human serum has been modified by the working group on Iron and Iron-Transport Proteins (Societe Francaise de Biologie Clinique). Ferene S is used as the chromogen, it is more sensitive and cheaper than bathophenanthroline. The sample size has been reduced from 2 to 0.5 ml. No interference could be shown with high concentrations of bilirubin, copper or hemoglobin. [less ▲]

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See detailModification of the thermoresistance to spray-drying of a cold-adapted subtilisin by genetic engineering
Bare, G.; Diakiese, A.; Zgoulli, S. et al

Poster (1998, May 08)

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See detailModification of the Thermoresistance to Spray-Drying of a Cold-Adapted Subtilisin by Genetic Engineering
Bare, G.; Diakiese, A.; Zgoulli, S. et al

in Applied Biochemistry and Biotechnology (1999), 77-79(Spring), 857-65

The thermoresistance of a cold-adapted subtilisin dried by spray-drying was studied. Proteolytic activity of this enzyme was measured before and after spray-drying. Without chemical additives, spray ... [more ▼]

The thermoresistance of a cold-adapted subtilisin dried by spray-drying was studied. Proteolytic activity of this enzyme was measured before and after spray-drying. Without chemical additives, spray-drying yields ranged from 2-13%. The use of arabic gum and lactose in the composition of the enzyme solutions allowed the strengthening of the enzyme structures and increased water mobility in the product. Increase of water mobility led to a shorter residence time of the product in the spray-drier and a net yield increase was obtained (yield higher than 50%). The effect of two selective mutations on the thermoresistance to spray-drying of the cold-adapted subtilisin was also investigated. Mutation T85D (introduction of an additional link with an ion Ca2+ necessary for enzyme activity, by substitution of Asp for Thr 85) had no effect on the thermoresistance of the subtilisin to spray-drying. Mutation H121W (introduction of an additional aromatic link by substitution of Trp for His 121) reduced the drying yield from 66% (not modified subtilisin) to 52%. This higher thermosensitivity could be explained by an increase of the hygroscopic character of the modified subtilisin (mutation H121W). [less ▲]

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See detailModification of the trapped field in bulk HTS as a result of the drilling of a pattern of artificial holes
Lousberg, G. P.; Fagnard, Jean-François ULg; Ausloos, Marcel ULg et al

in Journal of Physics: Conference Series (2010), 234

The trapped magnetic field is examined in bulk high-temperature superconductors that are artificially drilled along their c-axis. The influence of the hole pattern on the magnetization is studied and ... [more ▼]

The trapped magnetic field is examined in bulk high-temperature superconductors that are artificially drilled along their c-axis. The influence of the hole pattern on the magnetization is studied and compared by means of numerical models and Hall probe mapping techniques. To this aim, we consider two bulk YBCO samples with a rectangular cross-section that are drilled each by six holes arranged either on a rectangular lattice (sample I) or on a centered rectangular lattice (sample II). For the numerical analysis, three different models are considered for calculating the trapped flux: (i), a two-dimensional (2D) Bean model neglecting demagnetizing effects and flux creep, (ii), a 2D finite-element model neglecting demagnetizing effects but incorporating magnetic relaxation in the form of an E – J power law, and, (iii), a 3D finite element analysis that takes into account both the finite height of the sample and flux creep effects. For the experimental analysis, the trapped magnetic flux density is measured above the sample surface by Hall probe mapping performed before and after the drilling process. The maximum trapped flux density in the drilled samples is found to be smaller than that in the plain samples. The smallest magnetization drop is found for sample II, with the centered rectangular lattice. This result is confirmed by the numerical models. In each sample, the relative drops that are calculated independently with the three different models are in good agreement. As observed experimentally, the magnetization drop calculated in the sample II is the smallest one and its relative value is comparable to the measured one. By contrast, the measured magnetization drop in sample (1) is much larger than that predicted by the simulations, most likely because of a change of the microstructure during the drilling process. [less ▲]

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See detailModification ultrastructurale du nucléole au cours de l'ovogenèse chez un poisson téléostéen ovipare Barbus barbus.
Thiry, M.; Lepoint, A.; Poncin, Pascal ULg et al

in Cahiers d'Ethologie Appliquée (1993), 13(2), 247-248

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See detailModifications cognitives liées au vieillissement normal
Collette, Fabienne ULg

Scientific conference (2008, May 27)

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See detailModifications de l’activité cérébrale et troubles mnésiques dans le vieillissement
Collette, Fabienne ULg

Scientific conference (2010, November)

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See detailModifications de la mécanique ventilatoire et anomalies du rapport ventilation/perfusion dans la période opératoire et postopératoire.
Lamy, Maurice ULg; Damas, Pierre ULg

in Aspetti di patologia bronco-polmonare in anestesia e rianimazione (1984)

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See detailModifications des conduites émotionnelles chez les patients atteints de lésions frontales
Meulemans, Thierry ULg; Vincent, Eric ULg

in Van der Linden, Martial (Ed.) Neuropsychologie des lobes frontaux (1999)

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See detailModifications des membranes foetales de la ratte apres amniocentese (observations preliminaires).
Baeckeland, E.; Heinen, Ernst ULg

in Bulletin de l'Association des Anatomistes (1979), 63(180), 59-67

With the aid of scanning electron microscopy the normal pattern of both faces of amnion and visceral yolk sac were described. The inner face of the amnion turned towards the amniotic cavity is overlaid by ... [more ▼]

With the aid of scanning electron microscopy the normal pattern of both faces of amnion and visceral yolk sac were described. The inner face of the amnion turned towards the amniotic cavity is overlaid by large pavimentous cells bearing numerous microvilli. The opposite face, which delimits the exocoelome, consists of flattened fibroblasts separated by a fundamental connective substance. The two faces of the visceral yolk sac also show very different patterns. The exocoelomic face is covered by pavimentous cells ; these are smaller and bear less microvilli than amniotic cells. The yolk sac endoderm appears built up with prismatic or cubic cells, whose apical part is bulging and possesses a dense covering of microvilli. Amniocentesis effects are then reported. This intervention seems to provoke fetal membrane modifications only after 15 hours. These modifications essentially concern the visceral yolk sac whose exocoelomic cells are covered by more numerous microvilli which may show an intensification of a secretory process. [less ▲]

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See detailModifications des proteoglycans articulaires durant traitement par l'acide tiaprofénique
Reginster, Jean-Yves ULg; Gysen, P.; Malaise, Michel ULg et al

in Revue Médicale de Liège (1985), 40(17), 596-599

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See detailLes modifications du fonctionnement exécutif dans le vieillissement normal
Collette, Fabienne ULg; Salmon, Eric ULg

in Psychologie Française (2014), 59(1), 41-58

Il est maintenu bien reconnu que le vieillissement cognitif est associé à une diminution des capacités exécutives. Toutefois, si des déficits sont effectivement observés au sein des différentes fonctions ... [more ▼]

Il est maintenu bien reconnu que le vieillissement cognitif est associé à une diminution des capacités exécutives. Toutefois, si des déficits sont effectivement observés au sein des différentes fonctions, des dissociations entre performances préservées/altérées ont également été observées au sein de chacune. Dans cette revue de question, nous détaillerons les effets du vieillissement dans les fonctions de mise à jour, flexibilité, inhibition et coordination de tâches doubles, ainsi que les modifications au sein des réseaux cérébraux associés à ces processus. Nous discuterons également l'influence des capacités attentionnelles, des ressources en mémoire de travail et de certaines caractéristiques génétiques sur ces modifications. [less ▲]

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See detailModifications du tonus musculaire sous l'effet de l'entraînement isocinétique excentrique et concentrique chez le sujet sain
Monfils, Thierry; Croisier, Jean-Louis ULg; Havard, V. et al

in Actualités en Rééducation Fonctionnelle et Réadaptation, 20ème série (1995)

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