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See detailLuxury wine marketing
Heine, Klaus; Atwal, Glyn; Ates, Zelal ULg

in Charters; Gallo, Jérôme (Eds.) Wine Business Management (2014)

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See detailLV Mechanics in Mitral and Aortic Valve Diseases: Value of Functional Assessment Beyond Ejection Fraction.
Galli, Elena; LANCELLOTTI, Patrizio ULg; Sengupta, Partho P. et al

in JACC. Cardiovascular imaging (2014), 7(11), 1151-1166

The assessment of myocardial function in the context of valvular heart disease remains highly challenging. The myocardium deforms simultaneously in 3 dimensions, and global left ventricular (LV) function ... [more ▼]

The assessment of myocardial function in the context of valvular heart disease remains highly challenging. The myocardium deforms simultaneously in 3 dimensions, and global left ventricular (LV) function parameters such as volume and ejection fraction may remain compensated despite the changes in myocardial deformation properties. Current guidelines recommend valve replacement/repair in the presence of symptoms or reduced LV ejection fraction, but the resolution of symptoms or recovery of LV function post-surgery may not be reliably predicted. A wealth of evidence currently suggests that LV dysfunction is frequently subclinical despite normal ejection fraction. It may precede the onset of symptoms and portend a poor outcome due to progressive myocardial remodeling and dysfunction during the post-operative period. The advent of novel tissue-tracking echocardiography techniques has unleashed new opportunities for the clinical identification of early abnormalities in LV function. This review gathers and summarizes current evidence regarding the use of these techniques to assess myocardial deformation in patients with valvular heart disease. [less ▲]

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See detailLXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence
Andrusiak, Matthew; Vandenbosch, Renaud ULg; Dick, Frederick et al

in Cell Cycle (Georgetown, Tex.) (2013)

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See detailLa LXV Sessione della SIHDA
Cavalleri, Vanessa ULg

in Index : Quaderni Camerti di Studi Romanistici = International Survey of Roman Law (2012), 40

Detailed reference viewed: 100 (16 ULg)
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See detailLy 186655, a Phosphodiesterase Inhibitor, Inhibits Histamine Release from Human Basophils, Lung and Skin Fragments
Louis, Renaud ULg; Bury, Thierry ULg; Corhay, Jean-Louis ULg et al

in International Journal of Immunopharmacology (1992), 14(2), 191-4

LY 186655 (Tibenelast, Lilly) is a new phosphodiesterase inhibitor, not derived from the xanthine, possessing bronchodilating activity in animals. The aim of this work was to study the effect of LY 186655 ... [more ▼]

LY 186655 (Tibenelast, Lilly) is a new phosphodiesterase inhibitor, not derived from the xanthine, possessing bronchodilating activity in animals. The aim of this work was to study the effect of LY 186655 and theophylline on histamine release from human leukocytes, skin and lung fragments. Histamine was measured using a spectrofluorometric method. Both drugs (3 x 10(-5)-3 x 10(-3) M) exhibited a dose-dependent inhibition on anti-IgE (1/2000)-induced histamine release from human leukocytes. At 3 x 10(-3) M, theophylline was significantly more effective than LY 186655 (mean inhibition 94 and 42%, respectively). On lung fragments, theophylline and LY 186655 (3 x 10(-5)-3 x 10(-3) M) caused strong and comparable inhibitory effects on anti-IgE (1/500)-induced histamine release with a mean inhibition reaching maximally 65%. Histamine release induced by compound 48/80 (1 mg/ml) on sliced human foreskin was reduced with both drugs (3 x 10(-3) M) by about 37%. We conclude that LY 186655 inhibits in vitro immunological histamine release from human lung and cutaneous mast cells as well as basophils with a similar pattern of activity to theophylline. [less ▲]

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See detailA Lyalpha-only Active Galactic Nucleus from the Sloan Digital Sky Survey
Hall, Patrick B; Hoversten, Erik A; Tremonti, Christy A et al

in Astronomical Journal (The) (2004), 127

The Sloan Digital Sky Survey has discovered a z=2.4917 radio-loud active galactic nucleus (AGN) with a luminous, variable, low-polarization UV continuum, H I two-photon emission, and a moderately broad ... [more ▼]

The Sloan Digital Sky Survey has discovered a z=2.4917 radio-loud active galactic nucleus (AGN) with a luminous, variable, low-polarization UV continuum, H I two-photon emission, and a moderately broad Lyalpha line (FWHM~=1430 km s[SUP]-1[/SUP]) but without obvious metal-line emission. SDSS J113658.36+024220.1 does have associated metal-line absorption in three distinct, narrow systems spanning a velocity range of 2710 km s[SUP]-1[/SUP]. Despite certain spectral similarities, SDSS J1136+0242 is not a Lyman break galaxy. Instead, the Lyalpha and two-photon emission can be attributed to an extended, low-metallicity narrow-line region. The unpolarized continuum argues that we see SDSS J1136+0242 very close to the axis of any ionization cone present. We can conceive of two plausible explanations for why we see a strong UV continuum but no broad-line emission in this ``face-on radio galaxy'' model for SDSS J1136+0242: the continuum could be relativistically beamed synchrotron emission that swamps the broad-line emission, or more likely, SDSS J1136+0242 could be similar to PG 1407+265, a quasar in which for some unknown reason the high-ionization emission lines are very broad, very weak, and highly blueshifted. [less ▲]

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See detailLyapunov functions for stable cascades and applications to global stabilization
Mazenc, F.; Sepulchre, Rodolphe ULg; Jankovic, M.

in IEEE Transactions on Automatic Control (1999), 44(9), 1795-1800

This paper generalizes recent Lyapunov constructions for a cascade of two nonlinear systems one of which is stable rather than asymptotically stable. A new a cross term construction in the Lyapunov ... [more ▼]

This paper generalizes recent Lyapunov constructions for a cascade of two nonlinear systems one of which is stable rather than asymptotically stable. A new a cross term construction in the Lyapunov function allows us to replace earlier growth conditions by a necessary boudedness condition. This method is instrumental in the global stabilization of feedforward systems and new stabilization results are derived from the generalized construction. [less ▲]

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See detailLyapunov generation of entanglement and the correspondence principle
Petitjean, Cyril ULg; Jacquod, Ph

in PHYSICAL REVIEW LETTERS (2006), 97(19), 194103-4

We show how a classically vanishing interaction generates entanglement between two initially nonentangled particles, without affecting their classical dynamics. For chaotic dynamics, the rate of ... [more ▼]

We show how a classically vanishing interaction generates entanglement between two initially nonentangled particles, without affecting their classical dynamics. For chaotic dynamics, the rate of entanglement is shown to saturate at the Lyapunov exponent of the classical dynamics as the interaction strength increases. In the saturation regime, the one-particle Wigner function follows classical dynamics better and better as one goes deeper and deeper in the semiclassical limit. This demonstrates that quantum-classical correspondence at the microscopic level does not require coupling to a large number of external degrees of freedom. [less ▲]

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See detailLyapunov-based sufficient conditions for exponential stability in hybrid systems
Teel, Andrew; Forni, Fulvio ULg; Zaccarian, Luca

in IEEE Transactions on Automatic Control (2013)

Lyapunov-based sufficient conditions for exponential stability in hybrid systems are presented. The focus is on converting non-strict Lyapunov conditions, having certain observability properties, into ... [more ▼]

Lyapunov-based sufficient conditions for exponential stability in hybrid systems are presented. The focus is on converting non-strict Lyapunov conditions, having certain observability properties, into strict Lyapunov conditions for exponential stability. Both local and global results are considered. The utility of the results is illustrated through an example. [less ▲]

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See detailLe lycée Léonie de Waha
Charlier, Sébastien ULg

in Nouvelles du Patrimoine (Les) (2007), 115

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See detailThe Lyman-alpha telescope of the extreme ultraviolet imager on Solar Orbiter
Schühle, Udo; Halain, Jean-Philippe ULg; Meining, Stefan et al

in Proceedings of SPIE (2011), 8148

On the Solar Orbiter mission, the Extreme Ultraviolet Imager (EUI) set of filtergraph-telescopes consists of two high-resolution imagers (HRI) and one dual-band full Sun imager (FSI) that will provide ... [more ▼]

On the Solar Orbiter mission, the Extreme Ultraviolet Imager (EUI) set of filtergraph-telescopes consists of two high-resolution imagers (HRI) and one dual-band full Sun imager (FSI) that will provide images of the solar atmosphere in the extreme ultraviolet and in the Lyman-α line of hydrogen at 121.6 nm. The Lyman-α HRI, in particular, will provide imaging of the upper chromospheres/lower transition region of the Sun at unprecedented high cadence and at an angular resolution of one 1″ (corresponding to a spatial resolution of 200 km at perihelion). For vacuum-ultraviolet imaging of the Sun the main requirements for the instrumentation are high resolution, high cadence, and large dynamic range. We present here the novel solutions of the instrument design and show in detail the predicted performance of this telescope. We describe in detail how the high throughput and spectral purity at 121.6 nm is achieved. The technical solutions include multilayer coatings of the telescope mirrors for high reflectance at 121.6 nm, combined with interference filters and a multichannel-plate intensified CMOS active pixel camera. We make use of the design flexibilities of this camera to optimize the dynamic range in the focal plane. [less ▲]

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See detailLymecycline and minocycline in inflammatory acne: a randomized, double-blind intent-to-treat study on clinical and in vivo antibacterial efficacy.
Pierard, Claudine ULg; Goffin, Véronique ULg; Arrese Estrada, Jorge ULg et al

in Skin Pharmacology & Applied Skin Physiology (2002), 15(2), 112-9

BACKGROUND: Some antibiotics represent a mainstay in acne treatment. However, studies comparing their efficacies are rare. AIM: To evaluate the clinical and in vivo antibacterial effect of lymecycline and ... [more ▼]

BACKGROUND: Some antibiotics represent a mainstay in acne treatment. However, studies comparing their efficacies are rare. AIM: To evaluate the clinical and in vivo antibacterial effect of lymecycline and minocycline at different dosages. METHOD: Eighty-six patients with moderate to severe acne were enrolled in a randomized, double-blind, intent-to-treat study comparing in three parallel groups the effect of (1) lymecycline 300 mg daily for 12 weeks, (2) minocycline 50 mg daily for 12 weeks and (3) minocycline 100 mg daily for 4 weeks followed by 50 mg daily for 8 weeks. Evaluations were made at the screening visit and at five on-treatment visits. They consisted of clinical counts of acne lesions and evaluations of bacterial viability using dual flow cytometry performed on microorganisms collected from sebaceous infundibula by cyanoacrylate strippings. RESULTS: Patients receiving minocycline 100/50 mg had the best clinical outcome, particularly in the reduction of the number of papules. By the end of the trial, the microbial response to minocycline 100/ 50 mg was also superior to either of the other two treatments. There were less live and more dead bacteria. CONCLUSION: In this trial, minocycline 100/50 mg was superior for the treatment of inflammatory acne when compared to lymecycline 300 mg and minocycline 50 mg. [less ▲]

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See detailLymphangiogenesis
Paupert, Jenny ULg; Noël, Agnès ULg

in MacGraw-Hill Education Year Book of Sciences and Technology 2014 (2014)

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See detailLymphangiogenesis and extracellular matrix remodeling
Erpicum, Charlotte ULg; Detry, Benoît ULg; Paupert, Jenny ULg et al

Poster (2011)

Lymphangiogenesis, the formation of new lymphatic vessels from preexisting ones, is an important biological process associated with diverse pathologies, such as metastatic dissemination and graft ... [more ▼]

Lymphangiogenesis, the formation of new lymphatic vessels from preexisting ones, is an important biological process associated with diverse pathologies, such as metastatic dissemination and graft rejection. Our laboratory has previously identified MMP2 as a key regulator of lymphangiogenesis in vitro and in vivo. However, the exact function of MMP2 in this process is yet unknown. The present work aims at elucidating the mechanisms of MMP2 action during lymphangiogenesis. MMP2 could either act as a growth factor activator or as a regulator of matrix remodeling. To address this question, we studied the effect of MMP2 on lymphangiogenesis in an novel in vitro model of sprouting cells from small aggregates (spheroids) seeded in a collagen gel. In this model, quantification of the lymphangiogenic response is performed through computerized methods allowing the measurement of the distance of migration, but also the evaluation of how the cell are migrating. We evaluated the impact of MMP2 blockage through the use of physiological (TIMP2) or chemical inhibitors or by downregulating its expression with specific siRNA. The importance of extracellular matrix composition is evaluated by embedding these spheroids into different matrices (matrigel versus collagen; pepsinized collagen versus native collagen; different collagen concentrations). Our results reveal a modification of cell migration through collagen gel after MMP2 inhibition. The utilization of DQ collagen and microscopy refractance confirmed the importance of MMP2 collagenoyitic activity for lymphangiogenesis. [less ▲]

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See detailLymphangiogenesis and extracellular matrix remodeling
Erpicum, Charlotte ULg; Detry, Benoît ULg; Paupert, Jenny ULg et al

Conference (2013, January 28)

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