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See detailMETHOD FOR MONITORING COLLAGEN TYPE II DEGRADATION IN CARTILAGE
Reginster, Jean-Yves ULg; Deberg, Michelle; Henrotin, Yves ULg et al

Patent (2004)

A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most ... [more ▼]

A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals ultizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG, located in the helical region of collagen type II. [less ▲]

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See detailA method for plant leaf area measurement by using stereo vision
Leemans, Vincent ULg; Dumont, Benjamin ULg; Destain, Marie-France ULg et al

in Proceedings of CIGR-AgEng 2012 International Conference on Agricultural Engineering (2012, July)

This paper presents a method for the measurement of LAI of wheat in situ. By using stereoscopic images a 3D map was computed. One colour image was segmented to identify plant regions and the 3D leaf area ... [more ▼]

This paper presents a method for the measurement of LAI of wheat in situ. By using stereoscopic images a 3D map was computed. One colour image was segmented to identify plant regions and the 3D leaf area was computed on these regions. The result showed that the precision was about the same as for the reference measurements but required a lesser workload. [less ▲]

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See detailMethod for producing antibody using "naked" expression vector expressing type II transmembrane fusion protein
Renauld, Jean Christophe; Lemaire, Muriel; Dumoutier, Laurie et al

Patent (2012)

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See detailMethod for producing functionalized alkoxyamine initiator and use thereof
Detrembleur, Christophe ULg; Gross, Thomas; Meyer, Rolf-Volker

Patent (2004)

PROBLEM TO BE SOLVED: To provide a method for producing a functionalized alkoxyamine initiator and its use in radical polymerization process. ; SOLUTION: The invention provides a one-pot process for the ... [more ▼]

PROBLEM TO BE SOLVED: To provide a method for producing a functionalized alkoxyamine initiator and its use in radical polymerization process. ; SOLUTION: The invention provides a one-pot process for the production of a functionalized alkoxyamine of general formula (I) (for example, R<SP>1</SP>and R<SP>2</SP>are each H; R<SP>3</SP>is phenyl; and R<SP>4</SP>and R<SP>5</SP>together with nitrogen atom form an alicyclic 6-membered ring). The method includes (1) the formation of an aqueous phase and nitroxyl radical by reacting an oxidizing agent with a secondary amine having steric hindrance and (2) the removal of the aqueous phase and the addition of one or more vinyl monomers to the nitroxyl radical according to the method and system for the production of the radical. The invention further provides a monomer polymerization method using the functionalized alkoxyamine. [less ▲]

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See detailA Method for Spatial Deconvolution of Spectra
Courbin, F.; Magain, Pierre ULg; Kirkove, Murielle ULg et al

in Astrophysical Journal (2000), 529

A method for spatial deconvolution of spectra is presented. It follows the same fundamental principles as the ``MCS image deconvolution algorithm'' recently developed by Magain, Courbin, & Sohy and uses ... [more ▼]

A method for spatial deconvolution of spectra is presented. It follows the same fundamental principles as the ``MCS image deconvolution algorithm'' recently developed by Magain, Courbin, & Sohy and uses information contained in the spectrum of a reference point-spread function to spatially deconvolve spectra of very blended sources. An improved resolution rather than an infinite one is aimed at, overcoming the well-known problem of ``deconvolution artifacts.'' As in the MCS algorithm, the data are decomposed into a sum of analytical point sources and a numerically deconvolved background so that the spectrum of extended sources in the immediate vicinity of bright point sources may be accurately extracted and sharpened. The algorithm has been tested on simulated data including seeing variation as a function of wavelength and atmospheric refraction. It is shown that the spectra of severely blended point sources can be resolved while fully preserving the spectrophotometric properties of the data. Extended objects ``hidden'' by bright point sources (up to 4-5 mag brighter) can be accurately recovered as well, provided the data have a sufficiently high total signal-to-noise ratio (200-300 per spectral resolution element). Such spectra are relatively easy to obtain, even down to faint magnitudes, within a few hours of integration time with 10 m class telescopes. [less ▲]

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See detailMethod for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium suitable for radiolabeling without any evaporation step by the use of strong organic bases
Lemaire, Christian ULg; Voccia, Samuel; Aerts, Joël ULg et al

Patent (2009)

The present invention relates to a method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step characterised in that the eluting solution is a ... [more ▼]

The present invention relates to a method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step characterised in that the eluting solution is a organic solution having a water content <3%, containing at least: an organic solvent suitable for the subsequent radiolabelling reaction; a first compound (A) which is a molecule containing at least one acidic hydrogen and a second compound (B) which is an organic base sufficiently strong to be able to tear off the acidic hydrogen of first compound (A) in an acid-base reaction leading to the formation of an organic salt (S). [less ▲]

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See detailMethod for the enzymatic galactosylation of monosaccharides and oligosaccharides
Hoersch, Brigitte; Seiffert-Stoeriko, Andrea; Marquardt, Ruediger et al

Patent (1999)

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See detailMethod for the Measurement of Dechlorane 602 in Human Serum
Brasseur, Catherine ULg; Pirard; Focant, Jean-François ULg

in Organohalogen Compounds (2011), 73

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See detailMethod for the preliminary design of Piano Key Weirs
Machiels, Olivier ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Houille Blanche (2012), 4

The Piano Key Weir (PKW) is a particular geometry of weir associating to a labyrinth shape the use of overhangs to reduce the basis length. The PKW could thus be directly placed on a dam crest. Together ... [more ▼]

The Piano Key Weir (PKW) is a particular geometry of weir associating to a labyrinth shape the use of overhangs to reduce the basis length. The PKW could thus be directly placed on a dam crest. Together with its important discharge capacity for low heads, this geometric feature makes the PKW an interesting solution for dam rehabilitation. However, its hydraulic design remains problematic, even at a preliminary stage. This paper presents a preliminary design method based on results of experimental tests. The method enables to design project models by extrapolation of characteristics of existing idealized scale models. A practical application is presented to illustrate the method. [less ▲]

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See detailA method for the production of prebiotic preparations containing isomaltooligosaccharides and gluconic acid.
Goffin, Dorothée ULg; Blecker, Christophe ULg; Paquot, Michel ULg

Poster (2010, October 14)

Isomaltooligosaccharides (IMOs) are non-digestible oligosaccharides, considered as prebiotics and therefore aim to selectively feed probiotics indigenous to the human colon. IMOs consists of glucose ... [more ▼]

Isomaltooligosaccharides (IMOs) are non-digestible oligosaccharides, considered as prebiotics and therefore aim to selectively feed probiotics indigenous to the human colon. IMOs consists of glucose monomers linked by at least one α-1-6, or in a lower proportion α -1-3 (nigerose family) or α -1-2 (kojibiose family) glucosidic linkages. In our case they are produced from either corn, tapioca, or rice hydrolyzed starch. The enzymatic reaction is achieved using an Aspergillus niger transglucosidase (EC 2.4.1.24). It results in a very complex mixture with molecules characterized at the same time by their DP value (from 2 to ~15), linkages types (α-1-2, 3 or 6) and the proportion and position of each type of linkage (only α -1-6 or combined types). However, the reaction only permits to reach yields between 50-75 % in IMOs. Impurities are composed of residual maltooligosaccharides (glucose with exclusively α -1-4 linkages) from the starting vegetal material and glucose released during the transglucosylation step. These digestible saccharides are deleterious for the prebiotic preparation. Therefore, these compounds must be eliminated from the medium or converted in prebiotic species. Residual maltooligosaccharides are thus specifically hydrolyzed by a thermostable α-glucosidase (EC. 3.2.1.20) in order to produce glucose as the only unwanted specie. This glucose can then be converted to gluconic acid and/or its salts using a glucose-oxidase (EC. 1.1.3.4) in combination with a catalase. Gluconic acid (C6H12O7) is a saccharide derivative which has been recognized as a prebiotic compound. It is also known for its purgative action and proved to be effective for lipid peroxidation prevention. A first option can then be chosen, leaving gluconic acid in the product in order to obtain an original prebiotic product enjoying new prebiotic potential properties due to the combination of both types of prebiotic compounds (IMO and gluconic acid). The second option is to eliminate the gluconic acid from the prebiotic mixture. This separation doesn’t present the same difficulties than for glucose as gluconic acid is charged and can therefore be separated on anion-exchange resins (Dowex AcO-). This overall process, fulfilling the principles of green chemistry and being applicable to produce organic prebiotic, is an elegant solution, from an economical, an environmental, a nutri-functional and a techno-functional point of view. Indeed, it can lead to original prebiotic preparations, with yields close to 100%, by avoiding product loss, as the digestible saccharides portion is converted to gluconic acid. Furthermore, the presence of gluconic acid can provide many functional properties to the prebiotic preparations for their incorporation in food products. [less ▲]

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See detailMethod for the production of recombinant proteins by green microalgae
Versali, Marie-France ULg; Clerisse, Fabienne ULg; Dommes, Jacques ULg et al

Patent (2011)

The present invention relates to a method for the production of recombinant proteins by algal cells, which are fresh water unicellular green microalgae belonging to the order of Sphaeropleales. The ... [more ▼]

The present invention relates to a method for the production of recombinant proteins by algal cells, which are fresh water unicellular green microalgae belonging to the order of Sphaeropleales. The present invention further provides recombinant algal cells, wherein said algal cells are fresh water unicellular green microalgae belonging to the order of Sphaeropleales, and wherein said algal cells are capable of producing a recombinant protein. The invention is also directed to a method for selecting recombinant algal cells. The invention also relates to the use of recombinant algal cells as described herein for producing recombinant proteins. [less ▲]

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