Le point actuel sur l'utilisation de la vasopressine et de l'ocytocine en psychiatrie

in Médecine et Hygiène (1987), 45

Point Cannabis, Mission d’appui et d’analyse des données des dossiers et des fiches, Rapport 2009

Report (2009)

Le point de départ du délai de 5 ans en matière de récidive

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1988)

Le point de départ du délai de prescription de l'action publique pour le complice du délit d'organisation frauduleuse d'insolvabilité

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2005)

L'article s'attache à définir le point de départ du délai de prescription de l'action publique pour le complice du délit d'organisation frauduleuse d'insolvabilité. Il s'interroge encore sur les ... [more ▼]

L'article s'attache à définir le point de départ du délai de prescription de l'action publique pour le complice du délit d'organisation frauduleuse d'insolvabilité. Il s'interroge encore sur les répercussions de cette jurisprudence sur le point de départ du délai de prescription en matière de faux en écriture. [less ▲]

Point de vue de la SBAR

Conference (2008, December 06)

Point de vue et point d’écoute dans l’écriture “cinématographique” de Georges Simenon

in Traces (2001), 13

Point mutations in an infectious bovine viral diarrhoea virus type 2 cDNA transcript that yields an attenuated and protective viral progeny

in Vaccine (2005), 23(33), 4236-4246

An infectious cDNA clone of the hypervirulent bovine viral diarrhoea virus (BVDV) strain 890 (isolate 256) was produced by a streamlined PCR procedure. As compared to the published sequence of strain 890 ... [more ▼]

An infectious cDNA clone of the hypervirulent bovine viral diarrhoea virus (BVDV) strain 890 (isolate 256) was produced by a streamlined PCR procedure. As compared to the published sequence of strain 890, the nucleotide sequencing of cloned cDNA corresponding to isolate 256 revealed several mutations seven of which were attributed to the cloning procedure. The infectious transcript was transfected into permissive cells and led to viral multiplication (AvrII+ strain). In vitro, viral titres reached by the parental strain exceed those of the AvrII+ strain by more than one order of magnitude. The latter was clearly less virulent to young calves as indicated by clinical, haematological and virological parameters. Thirty-four days after inoculation with AvrII+ strain, calves were challenged with the virulent parental strain. The animals were protected as compared to unvaccinated controls. Therefore, our approach led to the production of an attenuated strain with potential use as a vaccine strain and will be useful for studies of virulence determinants in BVDV-2. (c) 2005 Elsevier Ltd. All rights reserved. [less ▲]

Point Mutations of Two Arginine Residues in the Streptomyces R61 Dd-Peptidase

in Biochemical Journal (1992), 283(1), 123-128

Incubation of the exocellular DD-carboxypeptidase/transpeptidase of Streptomyces R61 with phenylglyoxal resulted in a time-dependent decrease in the enzyme activity. This inactivation was demonstrated to ... [more ▼]

Incubation of the exocellular DD-carboxypeptidase/transpeptidase of Streptomyces R61 with phenylglyoxal resulted in a time-dependent decrease in the enzyme activity. This inactivation was demonstrated to be due to modification of the Arg-99 side chain. In consequence, the role of that residue was investigated by site-directed mutagenesis. Mutation of Arg-99 into leucine appeared to be highly detrimental to enzyme stability, reflecting a determining structural role for this residue. The conserved Arg-103 residue was also substituted by using site-directed mutagenesis. The modification to a serine residue yielded a stable enzyme, the catalytic properties of which were similar to those of the wild-type enzyme. Thus Arg-103, although strictly conserved or replaced by a lysine residue in most of the active-site penicillin-recognizing proteins, did not appear to fulfil any essential role in either the enzyme activity or structure. [less ▲]

Le point sur l'encéphalopathie spongiforme bovine et le nouveau variant de la maladie de Creutzfeldt-Jakob chez l'homme-les implications en santé publique et en réglementation de l'inspection des viandes

in Annales de Médecine Vétérinaire (1999), 143

Le point sur l’évaluation de la force des muscles respiratoires

in Revue Médicale de Liège (in press)

The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect ... [more ▼]

The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect, voluntary or involuntary. The conventional spirometry method assesses indirectly the respiratory function by measuring maximum inspiratory and expiratory pressure, which reflects the coordination of all respiratory muscles. Techniques of magnetic and electrical stimulation can detect a specific muscle dysfunction, independently of the patient's motivation, however they are invasive methods as measurements are made in the esophagus and stomach. The voluntary techniques are generally non-invasive and require patient's cooperation. Measures of respiratory muscle strength, coupled to a conventional spirometry, can predict the development of ventilatory support in patients at risk, and may be useful during weaning from mechanical ventilation in intensive care units. [less ▲]