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See detailInteractions between particles in a magnetocapillary self-assembly
Lagubeau, Guillaume ULg; Darras, Alexis; Grosjean, Galien ULg et al

Conference (2014, November 24)

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See detailInteractions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones
Zervosen, Astrid ULg; Lu, Wei-Ping; Chen, Zhouliang et al

in Antimicrobial Agents and Chemotherapy (2004), 48(3), 961-969

Several non-beta-lactam compounds were active against various gram-positive and gram-negative bacterial strains. The MICs of arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones were lower ... [more ▼]

Several non-beta-lactam compounds were active against various gram-positive and gram-negative bacterial strains. The MICs of arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones were lower than those of ampicillin and cefotaxime for methicillin-resistant Staphylococcus aureus M1339 and vancomycin-resistant Enterococcus faecium EF12. Several compounds were found to inhibit the cell wall synthesis of S. aureus and the last two steps of peptidoglycan biosynthesis catalyzed by ether-treated cells of Escherichia coli or cell wall membrane preparations of Bacillus megaterium. The effects of the arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-one derivatives on E. coli PBP 3 and PBP 5, Streptococcus pneumoniae PBP 2xS (PBP 2x from a penicillin-sensitive strain) and PBP 2xR (PBP 2x from a penicillin-resistant strain), low-affinity PBP 2a of S. aureus, and the Actinomadura sp. strain R39 and Streptomyces sp. strain R61 DD-peptidases were studied. Some of the compounds exhibited inhibitory activities in the 10 to 100 muM concentration range. The inhibition of PBP 2xS by several of them appeared to be noncompetitive. The dissociation constant for the best inhibitor (K-i = 10 muM) was not influenced by the presence of the substrate. [less ▲]

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See detailInteractions between polyamine and ethylene metabolisms in a hormone autonomous sugarbeet callus
Bisbis, Badia; Kevers, Claire ULg; Dommes, Jacques ULg et al

in Journal of Plant Physiology (2000), 157(1), 24-30

In a fully habituated non-organogenic sugarbeet callus (HNO) overproducing polyamines and underproducing ethylene (in comparison with its normal hormone-dependent counterpart), the question raised about a ... [more ▼]

In a fully habituated non-organogenic sugarbeet callus (HNO) overproducing polyamines and underproducing ethylene (in comparison with its normal hormone-dependent counterpart), the question raised about a possible competition between these two metabolites for their common precursor, S-adenosyl-methionine (SAM). The experimental strategy consisted in determining the effects of exogenous polyamines and inhibitors of polyamine biosynthetic pathway on growth, polyamine accumulation and ethylene production. Exogenous putrescine or spermidine decreased polyamine contents and ethylene production. Inhibitors of the diamine putrescine biosynthesis, DFMO and DFMA, induced a reduction of both polyamine content and ethylene production with an increase of HNO callus growth. However, when a mixture of the two inhibitors was used, an increase of ethylene production was observed without any effect on growth. The inhibitors of spermidine synthase (CHA) and of SAM decarboxylase (MGBG) also decreased polyamine content and ethylene production with different effects on growth according to the concentrations used. The combination of the two inhibitors (CHA + MGBG) increased ethylene production of the HNO callus. The effect of growth regulators (auxin and cytokinin) on growth and ethylene production of HNO callus is also discussed. These results suggest that polyamines affect directly the ethylene biosynthesis. In the absence of an exogenous hormonal control, the lower ethylene metabolism of HNO callus could not be explained by a competition with polyamines for their common precursor. [less ▲]

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See detailInteractions between Prolactin/Growth Hormone-Derived Peptides and PAI-1
D'Amico, Salvino ULg

Scientific conference (2010)

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See detailInteractions between systemic analgesics.
Joris, Jean ULg; Kaba, Abdourahmane ULg

in Acta Anaesthesiologica Belgica (2001), 52(4), 395-401

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See detailInteractions between the biofilm growth and the hydrodynamics in an aerobic trickling filter
Lekhlif, B.; Toye, Dominique ULg; Marchot, Pierre ULg et al

in Water Science & Technology (1994), 29

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See detailInteractions between the cytochrome pathway and the alternative oxidase in isolated Acanthamoeba castellanii mitochondria.
Jarmuszkiewicz, W.; Sluse, Francis ULg; Hryniewiecka, L. et al

in Journal of Bioenergetics & Biomembranes (2002), 34(1), 31-40

The steady-state activity of the two quinol-oxidizing pathways of Acanthamoeba castellanii mitochondria, the phosphorylating cytochrome pathway (i.e. the benzohydroxamate(BHAM)-resistant respiration in ... [more ▼]

The steady-state activity of the two quinol-oxidizing pathways of Acanthamoeba castellanii mitochondria, the phosphorylating cytochrome pathway (i.e. the benzohydroxamate(BHAM)-resistant respiration in state 3) and the alternative oxidase (i.e. the KCN-resistant respiration), is shown to be fixed by ubiquinone (Q) pool redox state independently of the reducing substrate (succinate or exogenous reduced nicotinamide adenine dinucleotide (NADH)), indicating that the active Q pool is homogenous. For both pathways, activity increases with the Q reduction level (up to 80%). However, the cytochrome pathway respiration partially inhibited (about 50%) by myxothiazol decreases when the Q reduction level increases above 80%. The decrease can be explained by the Q cycle mechanism of complex III. It is also shown that BHAM has an influence on the relationship between the rate of ADP phosphorylation and the Q reduction level when alternative oxidase is active, and that KCN has an influence on the relationship between the alternative oxidase activity and the Q reduction level. These unexpected effects of BHAM and KCN observed at a given Q reduction level are likely due to functional connections between the two pathways activities or to protein-protein interaction. [less ▲]

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See detailInteractions between the immune, endocrine and nervous systems
Geenen, Vincent ULg

Conference (1995, November)

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See detailInteractions between Tumoral Mcf7 Cells and Fibroblasts on Matrigel and Purified Laminin
Noël, Agnès ULg; Nusgens, Betty ULg; Lapiere, C. H. et al

in Matrix (Stuttgart, Germany) (1993), 13(4), 267-73

A reconstituted basement membrane (matrigel) and/or fibroblasts promote the growth of human breast tumors in athymic nude mice. We have investigated in vitro the effect of matrigel or purified ... [more ▼]

A reconstituted basement membrane (matrigel) and/or fibroblasts promote the growth of human breast tumors in athymic nude mice. We have investigated in vitro the effect of matrigel or purified glycoproteins (laminin and fibronectin) on tumoral MCF7 cells-fibroblasts interactions. In coculture on matrigel, MCF7 cells organized into clusters attached on top of fibroblasts aggregates. During the process resulting in tumor cells-fibroblasts aggregation, fibroblasts actively migrated while MCF7 cells were passively transported. Using purified proteins, specific antibodies and synthetic peptides, we show that cell aggregation induced by immobilized and soluble laminin is antagonized by exogenous fibronectin or fibronectin synthesized by fibroblasts. [less ▲]

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See detailInteractions between vegetation and rock chemical weathering: A study with a coupled hydrological and biogeochemical model
François, Louis ULg; Bureau, M.; Carignan, J. et al

in Geochimica et Cosmochimica Acta (2004), 68(11), 437-437

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See detailInteractions between western lowland gorillas (Gorilla gorilla gorilla Savage & Wyman 1847) and timber exploitation: Preliminary insights in a Gabonese logging concession
Haurez, Barbara ULg; Petre, Charles-Albert ULg; Doucet, Jean-Louis ULg

Poster (2012, August 15)

Interactions between western lowland gorillas (WLG) and a timber exploitation were studied in Central Gabon. WLG densities were estimated in two sites with different logging histories (not logged vs ... [more ▼]

Interactions between western lowland gorillas (WLG) and a timber exploitation were studied in Central Gabon. WLG densities were estimated in two sites with different logging histories (not logged vs. logged one month before), and nesting behavior was described. Seeds dispersed by WLG were identified through fecal analysis and germination trials assessed seed viability after gut passage. Four treatments were realized for the most abundant species: passed seeds, passed seeds in fecal matrix, seeds surrounded by fresh pulp and seeds extracted from fresh fruits. Relatively high WLG densities were observed in the concession (3.7 weaned gorillas/km² in unlogged forest and 1.7 weaned gorillas/km² in logged forest). WLG nested preferentially in open areas (particularly open terra firme and swamp forest) and frequently used old logging road network for nesting and feeding. WLG dispersed sixteen species during the course of the study (February-May 2011). The most dispersed species was Santiria trimera (Burseraceae). The germination successes of S. trimera were significantly higher after gut passage (N=378; P<0.001) because of pulp removal and seed coat scarification. This pilot study suggests that timber exploitation and WLG conservation are not mutually exclusive. WLG are important agents of forest regeneration by dispersing seeds in logged areas. Nest sites in logging gaps could be particularly favorable for seedlings development. This consideration must encourage forest managers to strengthen WLG-conservative practices in their concessions. [less ▲]

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See detailInteractions de cellules preleucemiques radio-induites et de greffe de moelle chez la Souris C57BL/Ka.
Humblet, Chantal ULg; Defresne, Marie-Paule ULg; Greimers, Roland ULg et al

in Comptes Rendus des Séances de la Société de Biologie et de ses Filiales (1987), 181(1), 82-7

The repopulation of thymus inoculated with radiation-induced preleukemia cells was studied in 400 R irradiated mice grafted with normal bone marrow cells. These marrow cells gave rise to an actively ... [more ▼]

The repopulation of thymus inoculated with radiation-induced preleukemia cells was studied in 400 R irradiated mice grafted with normal bone marrow cells. These marrow cells gave rise to an actively regenerating thymic progeny, as well as in 400 R treated mice receiving only a bone marrow graft. Moreover, the marrow graft did not prevent the progression of inoculated preleukemic cells towards lymphoma growth. [less ▲]

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See detailInteractions de glycolipides avec des membranes biomimétiques
Deleu, Magali ULg

Scientific conference (2013, March 18)

Les surfactants à base de sucre sont des composés d’intérêt pour les domaines alimentaire, cosmétique et pharmaceutique de par leur origine naturelle, leur biodégradabilité élevée et leur biocompatibilité ... [more ▼]

Les surfactants à base de sucre sont des composés d’intérêt pour les domaines alimentaire, cosmétique et pharmaceutique de par leur origine naturelle, leur biodégradabilité élevée et leur biocompatibilité. Récemment, certains ont également montré un potentiel dans le domaine de la protection des plantes. Depuis quelques années, les surfactants de type bolaforme ont reçu une attention particulière surtout pour leur potentiel d’exploitation en tant qu’agent d’encapsulation ou de vectorisation de médicaments. Leur structure est composée de deux têtes polaires connectées par un bras espaceur hydrophobe. Parmi les bolaamphiphiles, ceux à base de sucre offrent l’avantage de fournir une hydrosolubilité importante et une cytotoxicité réduite. Une connaissance approfondie des propriétés tensioactives et membranaires de ces nouveaux tensioactifs est une clef importante dans la compréhension de leurs mécanismes, d’une part, et d’autre part, dans l’optique d’une démarche prédictive dans la conception d’agents tensioactifs ciblant une application précise, du domaine physico-chimique ou biologique. Les outils tels que la technique de la cuve de Langmuir, la calorimétrie de titration isotherme, la spectroscopie de fluorescence et la spectroscopie infra-rouge ont été exploités afin de mettre en évidence l’influence de la longueur du bras hydrophobe, de la présence d’insaturation, de la stéréochimie des carbones anomères et de la nature des sucres sur les propriétés interfaciales et d’interaction/déstabilisation des membranes biologiques des bolaformes de sucre. [less ▲]

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See detailInteractions de la mycosubtiline avec les membranes biomimétiques. Apport de l’optique non linéaire
Nasir, Mehmet Nail ULg; Besson, Françoise

Scientific conference (2011)

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See detailInteractions des androgenes et des oestrogenes dans le controle de la reproduction
Schumacher, M.; Alexandre, Corine; Balthazart, Jacques ULg

in Comptes Rendus de l'Académie des Sciences. Série III, Sciences de la Vie (1987), 305(14), 569-74

Castrated male quail were injected with the synthetic oestrogen, diethylstylbestrol (DES) or the synthetic androgen, methyltrienolone (R 1881) or both compounds simultaneously. Both R 1881 and DES ... [more ▼]

Castrated male quail were injected with the synthetic oestrogen, diethylstylbestrol (DES) or the synthetic androgen, methyltrienolone (R 1881) or both compounds simultaneously. Both R 1881 and DES activated male sexual behaviour, inhibited LH and FSH secretion and increased hypothalamic aromatase activity. Additive effects between R 1881 and DES were observed for the induction of brain aromatase and for the inhibition of FSH secretion. As a consequence, mechanisms mediated by androgen and estrogen receptors must be involved in the control of these reproductive characteristics. [less ▲]

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