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See detailHow well do traffic engineering objective functions meet TE requirements?
Balon, Simon ULg; Skivée, Fabian ULg; Leduc, Guy ULg

in Lecture Notes in Computer Science (2006, May), 3976

We compare and evaluate how well-known and novel networkwide objective functions for Traffic Engineering (TE) algorithms fulfil TE requirements. To compare the objective functions we model the TE problem ... [more ▼]

We compare and evaluate how well-known and novel networkwide objective functions for Traffic Engineering (TE) algorithms fulfil TE requirements. To compare the objective functions we model the TE problem as a linear program and solve it to optimality, thus finding for each objective function the best possible target of any heuristic TE algorithm. We show that all the objective functions are not equivalent and some are far better than others. Considering the preferences a network operator may have, we show which objective functions are adequate or not. [less ▲]

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See detailHOW WELL DO WE KNOW THE KOBAYASHI-MASKAWA MATRIX?
Cudell, Jean-René ULg; Halzen, F.; Pakvasa, S.

in Phys. Rev. (1989), D40

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See detailHow women’s entrepreneurship builds on collaborative entrepreneurship
Constantinidis, Christina ULg

in ISBE (Ed.) ISBE Conference 2016 Proceedings (2016, October 27)

This communication is part of a larger research project that aims to develop and test a model about the collaboration practices of female entrepreneurs, through identifying antecedents and consequences ... [more ▼]

This communication is part of a larger research project that aims to develop and test a model about the collaboration practices of female entrepreneurs, through identifying antecedents and consequences for entrepreneurial success. The objective of our communication is to explore collaborative entrepreneurship, an emerging topic in the literature, from the perspective of female entrepreneurs in Luxembourg. We share here the first insights brought by our exploratory study on this relatively underinvestigated topic, in particular in the women’s entrepreneurship field. Through the analysis of an in-depth longitudinal case study with two women entrepreneurs who created and developed a business collaboration, completed by a set of qualitative interviews with other women entrepreneurs working in collaboration, we are able to propose a first understanding of this phenomenon and to establish the bases for a theoretical model. [less ▲]

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See detailHOX Gene Aberrant Expression in Skin Melanoma: A Review.
PIERARD, Gérald ULg; Franchimont, Claudine ULg

in Journal of skin cancer (2012), 2012

The homeobox family and its subset of HOX gene products represent a family of transcription factors directing DNA-protein and protein-protein interactions. In the embryo, they are central regulators in ... [more ▼]

The homeobox family and its subset of HOX gene products represent a family of transcription factors directing DNA-protein and protein-protein interactions. In the embryo, they are central regulators in cell differentiation during morphogenesis. A series of genes of the four HOX gene clusters A, B, C, and D were reported to show aberrant expressions in oncogenesis, particularly in cutaneous malignant melanoma (CMM). They are involved in cell proliferation and progression in the CMM metastatic path. We present relevant peer-reviewed literature findings about the aberrant expression of HOX genes in CMM. The number of CMM cell nuclei exhibiting aberrant HOX protein expression appears correlated with tumour progression. [less ▲]

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See detailHox protein interactions: screening and network building.
Bergiers, Isabelle; Lambert, Barbara; Daakour, Sarah ULg et al

in Methods in molecular biology (Clifton, N.J.) (2014), 1196

Understanding the mode of action of Hox proteins requires the identification of molecular and cellular pathways they take part in. This includes to characterize the networks of protein-protein ... [more ▼]

Understanding the mode of action of Hox proteins requires the identification of molecular and cellular pathways they take part in. This includes to characterize the networks of protein-protein interactions involving Hox proteins. In this chapter we propose a strategy and methods to map Hox interaction networks, from yeast two-hybrid and high-throughput yeast two-hybrid interaction screening to bioinformatic analyses based on the software platform Cytoscape. [less ▲]

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See detailHoxc5 and Hoxc8 Expression Are Selectively Turned on in Human Cervical Cancer Cells Compared to Normal Keratinocytes
Alami, Y.; Castronovo, Vincenzo ULg; Belotti, D. et al

in Biochemical and Biophysical Research Communications (1999), 257(3), 738-45

A growing number of data have sustained the involvement of homeobox genes expression deregulation in cancer. In this study, we have performed an exhaustive survey of the expression of the 39 class I HOX ... [more ▼]

A growing number of data have sustained the involvement of homeobox genes expression deregulation in cancer. In this study, we have performed an exhaustive survey of the expression of the 39 class I HOX genes expressed in normal and malignant human cervix keratinocytes. Using RT-PCR, we observed that the vast majority (34/39) of HOX genes are expressed in normal keratinocytes. Only HOXA2, HOXA7, HOXC5, HOXC8 and HOXD12 were found to be silent. Interestingly, this pattern is conserved in the transformed keratinocytes (SiHa cells) except for the appearance of HOXC5 and HOXC8 mRNA. The HOXC5 and HOXC8 expression was also observed in two other transformed keratinocytes cell lines of independent origins, Eil-8 and 18-11S3, and confirmed by in situ hybridization. Our data add weight to the body of evidence attributing to a specific adult tissue a particular combination of expressed HOX genes and suggest that HOXC5 and/or HOXC8 could be involved in the process leading to the transformation of cervical keratinocytes. [less ▲]

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See detailThe HOXC6 homeodomain-containing proteins
Chariot, Alain ULg; Gielen, jacques

in International Journal of Biochemistry & Cell Biology (1998), 30

The HOXC6 homeodomain-containing proteins act as transcription factors in the genetic control of multiple genes involved in development and cell differentiation. Two HOXC6 polypeptides are encoded by a ... [more ▼]

The HOXC6 homeodomain-containing proteins act as transcription factors in the genetic control of multiple genes involved in development and cell differentiation. Two HOXC6 polypeptides are encoded by a single homeobox ('HOX') gene described as 'master gene' for the crucial role it plays in the patterning and axial morphogenesis of multiple species. Transcription of the HOXC6 gene is initiated from two promoters and generates two proteins that share the same DNA-binding domain but harbor a distinct N-terminal region. Recent studies have demonstrated that both HOXC6 products can activate or repress transcription, depending on the cellular context. Functional in vivo specificity of HOXC6 proteins may be achieved through combinatorial interactions with other members of the HOX family as well as with co-factors whose identities are largely unknown. Disruption of this 'HOX code' may lead to pathology such as developmental defects. [less ▲]

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See detailHpa Axis Dysfunction in Major Depression: Relationship to 5-Ht(1a) Receptor Activity
Pitchot, William ULg; Herrera, C.; Ansseau, Marc ULg

in Neuropsychobiology (2001), 44(2), 74-7

Major depression is associated with a dysfunction of the serotonergic activity and the hypothalamic-pituitary-adrenal (HPA) axis. Moreover, a reciprocal relationship between the serotonergic and HPA axis ... [more ▼]

Major depression is associated with a dysfunction of the serotonergic activity and the hypothalamic-pituitary-adrenal (HPA) axis. Moreover, a reciprocal relationship between the serotonergic and HPA axis systems has been hypothesized. The purpose of the present study was to assess the relationship between sensitivity of 5-HT(1A) receptors as measured by hormonal (ACTH, cortisol and PRL) and temperature responses to flesinoxan and HPA axis activity as measured by the dexamethasone suppression test. The sample included 21 inpatients with major depression. Dexamethasone nonsuppressors exhibited lower ACTH responses to flesinoxan as compared with dexamethasone suppressors. The results showed that a dysfunction in 5-HT(1A) receptor activity could be due to a hypersecretion of cortisol. [less ▲]

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See detailHPAEC-PAD profiles of maltooligosaccharide produced by hydrolysis of sorghum starches using amylases from various sources
Boudries, Nadia; Sindic, Marianne ULg; Belhaneche-Bensemra, Naima et al

in International Journal of Biotechnology and Food Science (2015), 3 (4)

Starches isolated from white and pigmented sorghum (Sorghum bicolor (L.) Moench) were used to determine enzymatic activity of starch hydrolysis by fungal (Aspergillus Oryzae) and bacterial (Bacillus ... [more ▼]

Starches isolated from white and pigmented sorghum (Sorghum bicolor (L.) Moench) were used to determine enzymatic activity of starch hydrolysis by fungal (Aspergillus Oryzae) and bacterial (Bacillus Subtilis) α-amylase and oligosaccharides profiles of hydrolysate was determinate in same conditions by High Performance Exchange Anion Chromatography with Pulsed Amperometric Detection (HPEAC-PAD). Pure starches from potato, amylose and amylopectin were used for comparison. Oligosaccharide compositions ranging from glucose (DP1) to maloheptaose (DP7) as well as the significantly effect of α-amylase source and starch structure were determined. [less ▲]

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See detailHpatitis C infection: eligibility for antiviral therapies
El souda, R; DELWAIDE, Jean ULg; GERARD, Christiane ULg et al

in Acta Gastro-Enterologica Belgica (2004), 67

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See detailHPLC determination of fenofibric acid in human plasma using automated solid phase extraction as sample preparation
Streel, B.; Zimmer, C.; Sibenaler-Dechamps, R. et al

in Journal de Pharmacie de Belgique (1995), 50

Detailed reference viewed: 47 (2 ULg)
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See detailHPLC enantiomeric separation of B-blocking drugs using an alpha 1-acid glycoprotein column
Ceccato, Attilio ULg; Hubert, Philippe ULg; Streel, Bruno et al

in Journal de Pharmacie de Belgique (1993), 48

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See detailHPLC in neurochemistry
Bontemps, J; Laschet, L; Bettendorff, Lucien ULg et al

Poster (1984, May 18)

Detailed reference viewed: 20 (0 ULg)