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See detailLa loyauté dans les procédures arbitrales
Kohl, Benoît ULg

in Liber Amicorum Guy Keutgen (2012)

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See detailLRPPRC mutations cause a phenotypically distinct form of Leigh syndrome with cytochrome c oxidase deficiency.
DEBRAY, François-Guillaume ULg; Morin, C.; Janvier, Annie et al

in Journal of Medical Genetics (2011)

Background The natural history of all known patients with French-Canadian Leigh disease (Saguenay-Lac-St-Jean cytochrome c oxidase deficiency, MIM220111, SLSJ-COX), the largest known cohort of patients ... [more ▼]

Background The natural history of all known patients with French-Canadian Leigh disease (Saguenay-Lac-St-Jean cytochrome c oxidase deficiency, MIM220111, SLSJ-COX), the largest known cohort of patients with a genetically homogeneous, nuclear encoded congenital lactic acidosis, was studied. Results 55 of 56 patients were homozygous for the A354V mutation in LRPPRC. One was a genetic compound (A354V/C1277Xdel8). Clinical features included developmental delay, failure to thrive, characteristic facial appearance and, in 90% of patients, acute crises that have not previously been detailed, either metabolic (fulminant lactic acidosis) and/or neurological (Leigh syndrome and/or stroke-like episodes). Survival ranged from 5 days to >30 years. 46/56 patients (82%) died, at a median age of 1.6 years. Of 73 crises, 38 (52%) were fatal. The immediate causes of death were multiple organ failure and/or Leigh disease. Major predictors of mortality during crises (p<0.005) were hyperglycaemia, hepatic cytolysis, and altered consciousness at admission. Compared to a group of SURF1-deficient Leigh syndrome patients assembled from the literature, SLSJ-COX is distinct by the occurrence of metabolic crises, leading to earlier and higher mortality (p=0.001). Conclusion SLSJ-COX is clinically distinct, with acute fatal acidotic crises on a backdrop of chronic moderate developmental delay and hyperlactataemia. Leigh syndrome is common. Stroke-like episodes can occur. The Leigh syndrome of SLSJ-COX differs from that of SURF1-related COX deficiency. SLSJ-COX has a different spectrum of associated abnormalities, acidotic crises being particularly suggestive of LRPPRC related Leigh syndrome. Even among A354V homozygotes, pronounced differences in survival and severity occur, showing that other genetic and/or environmental factors can influence outcome. [less ▲]

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See detailLSD1 cooperates with CTIP2 to promote HIV-1 transcriptional silencing.
Le Douce, Valentin; Colin, Laurence; Redel, Laetitia et al

in Nucleic Acids Research (2012), 40(5), 1904-15

Microglial cells are the main HIV-1 targets in the central nervous system (CNS) and constitute an important reservoir of latently infected cells. Establishment and persistence of these reservoirs rely on ... [more ▼]

Microglial cells are the main HIV-1 targets in the central nervous system (CNS) and constitute an important reservoir of latently infected cells. Establishment and persistence of these reservoirs rely on the chromatin structure of the integrated proviruses. We have previously demonstrated that the cellular cofactor CTIP2 forces heterochromatin formation and HIV-1 gene silencing by recruiting HDAC and HMT activities at the integrated viral promoter. In the present work, we report that the histone demethylase LSD1 represses HIV-1 transcription and viral expression in a synergistic manner with CTIP2. We show that recruitment of LSD1 at the HIV-1 proximal promoter is associated with both H3K4me3 and H3K9me3 epigenetic marks. Finally, our data suggest that LSD1-induced H3K4 trimethylation is linked to hSET1 recruitment at the integrated provirus. [less ▲]

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See detailLSP sneutrino decays
Aristizabal Sierra, Diego ULg; Restrepo, Diego; Spinner, Sogee

in Journal of High Energy Physics [=JHEP] (2013), 1305

In bilinear R-parity violation (BRpV), in which the superpotential includes a bilinear term between the lepton doublet and the up-type Higgs superfields, a sneutrino LSP can decay into pairs of heavy ... [more ▼]

In bilinear R-parity violation (BRpV), in which the superpotential includes a bilinear term between the lepton doublet and the up-type Higgs superfields, a sneutrino LSP can decay into pairs of heavy standard model states: W's, Z's, tops or Higgs bosons. These finals states can dominate over the traditionally considered bottom pair final state. This would lead to unique and novel supersymmetric signals with each supersymmetric event possibly producing two pairs of these heavy standard model fields. We investigate this possibility and find that the branching ratio into heavier states dominates when the bilinear term is much smaller than the sneutrino vacuum expectation value for a given sneutrino flavor. When BRpV is the only source of neutrino masses these decays can only dominate for one of the sneutrino generations. Relaxing this constraint opens these channels for all three generations. [less ▲]

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See detail@LTER et la Pl@teforme FLE de l’ULg, Compte-rendu d’expériences et d’expérimentations
Thonard, Audrey ULg; Gueury, Véronique ULg

in Langage et l'Homme (Le) : Recherches Pluridisciplinaires sur le Langage (2012), 47(1),

L’enseignement des langues en ligne a fait son apparition il y a quelques années à l’Université de Liège. Celle-ci a opté, dans un premier temps, pour un logiciel commercialisé puis a investi dans la ... [more ▼]

L’enseignement des langues en ligne a fait son apparition il y a quelques années à l’Université de Liège. Celle-ci a opté, dans un premier temps, pour un logiciel commercialisé puis a investi dans la création de cours complets en ligne, conçus par une équipe d’enseignants de l’Institut Supérieur des Langues Vivantes et baptisés @LTER. Fort de cette expérience, cet Institut a souhaité partager ses compétences avec les futurs professeurs de français langue étrangère dans le cadre de leur cursus universitaire. Cet article se propose d’aborder ces diverses expériences avec les TICe et ces nouvelles pratiques pédagogiques et didactiques adoptées par l’ULg pour l’apprentissage et l’enseignement du français langue étrangère. La première partie de l’article traite du dispositif mis en place à l’attention des étudiants Erasmus « in » ; la seconde rapportera les réflexions, les observations et les expérimentations qui ont entraîné des révisions régulières du programme du cours intitulé « Les TICe pour l’apprentissage/enseignement du FLE », inscrit au programme du Master en Didactique du FLE à l’Université de Liège, et qui ont finalement donné le jour à la Pl@teforme FLE de l’ULg. [less ▲]

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See detailLe LTP : Un jeu pour le diagnostic, l'intervention et la recherche
Miscioscia, Marina ULg; Lejeune, Génévieve

Conference (2014, May 16)

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See detailLubrication by charged polymers
Raviv, Uri; Giasson, Suzanne; Kampf, Nir et al

in Nature (2003), 425(6954), 163-165

Long-ranged forces between surfaces in a liquid control effects from colloid stability [1] to biolubrication [2], and can be modified either by steric factors due to flexible polymers [3], or by surface ... [more ▼]

Long-ranged forces between surfaces in a liquid control effects from colloid stability [1] to biolubrication [2], and can be modified either by steric factors due to flexible polymers [3], or by surface charge effects [4]. In particular, neutral polymer 'brushes' may lead to a massive reduction in sliding friction between the surfaces to which they are attached [5-7], whereas hydrated ions can act as extremely efficient lubricants between sliding charged surfaces [8]. Here we show that brushes of charged polymers (polyelectrolytes) attached to surfaces rubbing across an aqueous medium result in superior lubrication compared to other polymeric surfactants. Effective friction coefficients with polyelectrolyte brushes in water are lower than about 0.0006-0.001 even at low sliding velocities and at pressures of up to several atmospheres (typical of those in living systems). We attribute this to the exceptional resistance to mutual interpenetration displayed by the compressed, counterion-swollen brushes, together with the fluidity of the hydration layers surrounding the charged, rubbing polymer segments. Our findings may have implications for biolubrication effects, which are important in the design of lubricated surfaces in artificial implants, and in understanding frictional processes in biological systems. [less ▲]

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See detailLuc et Jean-Pierre Dardenne. Vingt ans de travail en cinéma et vidéo (1976-1996)
Van Cauwenberge, Geneviève ULg; Bajomée, Danielle ULg; Delruelle, Edouard ULg et al

in Revue belge du cinéma (1997), 41(Hiver), 96

Historical and analytical overview of the Dardenne’s cinématographic and videographic work from 1976 to 1996, with an interview with Luc and Jean-Pierre Dardenne. A lot of issues about the survivor’s ... [more ▼]

Historical and analytical overview of the Dardenne’s cinématographic and videographic work from 1976 to 1996, with an interview with Luc and Jean-Pierre Dardenne. A lot of issues about the survivor’s memory, the history consciousness, the wounds of memory, the survivor’s speech ; the memory of the social struggle ; the derelction and the transformation of the society ; the résistance ; the videographic and filmic forms and patterns (landscape, face, water, reality) ; the theatrical space and the relations between theatre and cinéma. [less ▲]

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See detailLuc Gazon, peintures et dessins
Duchesne, Jean-Patrick ULg

in Art&Fact (1982), 1

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See detailLuc Grossen, une figure de l’art engagé
Bawin, Julie ULg

in Art Même : Chronique des Arts Plastiques de la Communauté française de Belgique (2006), (30), 33

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See detailLuc Pire sans Luc Pire
Habrand, Tanguy ULg

Article for general public (2009)

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See detailLuc Tuymans : "le monde de l'art ne doit pas entrer dans mon atelier"
Bawin, Julie ULg

in Flux News (trimestriel d'art contemporain) (2007), (43), 11-12

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See detailLucerne, le 30 juin 1939. Des tableaux “d’art dégénéré” pour Liège
Duchesne, Jean-Patrick ULg

in Duchesne, Jean-Patrick (Ed.) L’art dégénéré selon Hitler. La vente de Lucerne, 1939 (2014)

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See detailLucien Jottrand et l'Europe médiane. Les théories européennes de deux Belges
Peters, Arnaud ULg

Master's dissertation (2001)

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See detailLucien Lambotte, esquisse biographique
Pirenne, Christophe ULg

in Revue de la Société liégeoise de Musicologie (2001), 18

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See detailLucienne Stassaert
Spinoy, Erik ULg

in Brems, Hugo; Van Deel, Tom; Zuiderent, Ad (Eds.) Kritisch lexicon van de Nederlandstalige literatuur na 1945 (1986)

This is a presentatiion and survey of the work of Flemish modernist poet Lucienne Stassaert.

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See detailLucienne Stassaert of de verwoording van een visie
Spinoy, Erik ULg

in Dietsche Warande en Belfort (1986), 131(4), 289-294

This article is a study of recent work by Flemish modernist poet Lucienne Stassaert.

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See detailLucites par photosensibilisation.
Claessens, Nadine; Pierard, Claudine ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2005), 60 Suppl 1

There exists a series of photodermatoses due to phototoxic or photoallergic reactions. Anamnestic and clinical clues supplemented by dermatopathological examination and photobiological tests are key ... [more ▼]

There exists a series of photodermatoses due to phototoxic or photoallergic reactions. Anamnestic and clinical clues supplemented by dermatopathological examination and photobiological tests are key features for reaching the correct diagnosis and the adequate choice of therapy. [less ▲]

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See detailLucius Annaeus Senace, Tragoediae, Index verborum; relevés lexicaux et grammaticaux
Denooz, Joseph ULg

Book published by Olms - Deuxième édition en 1996 (1980)

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