Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Peer Reviewed
See detailMicroporosimétrie quantitative de roches et matériaux par analyse d'images
Pirard, Eric ULg; Pierroux, Alain

in Annales de la Société Géologique de Belgique (1992), 115(1), 245-252

Detailed reference viewed: 31 (1 ULg)
Full Text
Peer Reviewed
See detailMicroporosity formation in nickel-base superalloys in relation to their solidification sequence
Lecomte-Beckers, Jacqueline ULg; Lamberigts, M.

in Proceedings of the International Conference of High Temperature Alloys for Gas Turbine and Other Applications (1986)

This work is aimed at showing how the proneness of superalloys to microporosity formation can be estimated by the tsP* pararneter which makes use of various solidification features. The latter can be ... [more ▼]

This work is aimed at showing how the proneness of superalloys to microporosity formation can be estimated by the tsP* pararneter which makes use of various solidification features. The latter can be derived from quantitative differential thermal analysis (DTA) resuits through the original method described in the text. The technique was applied to two IN 100 master meUs of distinct grades (virgin or revert) which had been showrt to behave very differently in the foundry. It led to ascribe the poorer performance of the revert meit to its particular solidification sequence leading higher dendrite tortuosity and lesser residual liquid fluidity. [less ▲]

Detailed reference viewed: 46 (3 ULg)
Full Text
Peer Reviewed
See detailMicroporous and heterogeneous surface adsorption isotherms arising from Levy distributions
Brouers, François ULg; Sotolongo, O.; Marquez, F. et al

in Physica A: Statistical Mechanics and its Applications (2005), 349(1-2), 271-282

We show that for adsorption on heterogeneous and microporous surfaces, the Freundlich isotherm power-law exponent a is directly related to the Levy tail index of the distribution of the Langmuir parameter ... [more ▼]

We show that for adsorption on heterogeneous and microporous surfaces, the Freundlich isotherm power-law exponent a is directly related to the Levy tail index of the distribution of the Langmuir parameter b and to the expected value and the variance of the adsorption energy distribution. This allows us to view adsorption at low pressure in these systems as a rare event dominated phenomena. Based on this discussion, a generalized isotherm formulation is proposed and applied to the interpretation of recent data on activated carbons. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]

Detailed reference viewed: 30 (3 ULg)
See detailLes microprolactinomes : diagnostic clinique, biologique et radiologique
Burlacu, M. C.; Daly, Adrian ULg; Beckers, Albert ULg

in Young, Jacques (Ed.) Hyperprolactinémies (2008)

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailMicroreactor Technology as an Efficient Tool for Multicomponent Reactions
Cukalovic, Ana; Monbaliu, Jean-Christophe ULg; Stevens, Christian

in Orru, Romano; Ruijter, Eelco (Eds.) Topics in Heterocyclic Chemistry: Synthesis of Heterocycles via Multicomponent Reactions I (2010)

Detailed reference viewed: 17 (5 ULg)
Full Text
Peer Reviewed
See detailMicroRNA Targeting of CoREST controls polarization of migrating cortical neurons
Volvert; Prévot, Pierre-Paul; Close, Pierre ULg et al

in Cell Reports (2014), 7(4), 1168-83

Detailed reference viewed: 18 (4 ULg)
See detailMicroRNA targeting of CoREST controls polarization of migrating cortical neurons.
Volvert, M. L.; Prevot, Pierre-Paul ULg; Pirotte, S. et al

Poster (2013)

Detailed reference viewed: 18 (1 ULg)
Peer Reviewed
See detailMicroRNA-146a is a causative factor and a specific biomarker for peripartum cardiomyopathy
Halkein, Julie ULg; Tabruyn, Sébastien ULg; Haghikia, Arash et al

Poster (2012, April)

Detailed reference viewed: 48 (3 ULg)
Full Text
Peer Reviewed
See detailMicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy.
Halkein, Julie ULg; Tabruyn, Sebastien P.; Ricke-Hoch, Melanie et al

in Journal of Clinical Investigation (2013), 123(5), 2143-54

Peripartum cardiomyopathy (PPCM) is a life-threatening pregnancy-associated cardiomyopathy in previously healthy women. Although PPCM is driven in part by the 16-kDa N-terminal prolactin fragment (16K PRL ... [more ▼]

Peripartum cardiomyopathy (PPCM) is a life-threatening pregnancy-associated cardiomyopathy in previously healthy women. Although PPCM is driven in part by the 16-kDa N-terminal prolactin fragment (16K PRL), the underlying molecular mechanisms are poorly understood. We found that 16K PRL induced microRNA-146a (miR-146a) expression in ECs, which attenuated angiogenesis through downregulation of NRAS. 16K PRL stimulated the release of miR-146a-loaded exosomes from ECs. The exosomes were absorbed by cardiomyocytes, increasing miR-146a levels, which resulted in a subsequent decrease in metabolic activity and decreased expression of Erbb4, Notch1, and Irak1. Mice with cardiomyocyte-restricted Stat3 knockout (CKO mice) exhibited a PPCM-like phenotype and displayed increased cardiac miR-146a expression with coincident downregulation of Erbb4, Nras, Notch1, and Irak1. Blocking miR-146a with locked nucleic acids or antago-miRs attenuated PPCM in CKO mice without interrupting full-length prolactin signaling, as indicated by normal nursing activities. Finally, miR-146a was elevated in the plasma and hearts of PPCM patients, but not in patients with dilated cardiomyopathy. These results demonstrate that miR-146a is a downstream-mediator of 16K PRL that could potentially serve as a biomarker and therapeutic target for PPCM. [less ▲]

Detailed reference viewed: 76 (26 ULg)
Full Text
Peer Reviewed
See detailMicroRNA-146a, a downstream effector of 16kDa prolactin, impairs the endothelium-cardiomyocyte cross-talk in peripartum cardiomyopathy
Struman, Ingrid ULg; Halkein, Julie ULg; Tabruyn, Sébastien ULg et al

in FASEB meeting:the Growth Hormone/Prolactin Family in Biology and Disease. (2012)

Detailed reference viewed: 17 (2 ULg)
Peer Reviewed
See detailmicroRNA-21 Exhibits Anti-Angiogenic Function by Targeting RhoB Expression in Endothelial Cells
Sabatel, Céline; Malvaux, Ludovic; Bovy, Nicolas ULg et al

Poster (2011, February)

Detailed reference viewed: 9 (3 ULg)
Full Text
Peer Reviewed
See detailMicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells.
Sabatel, Céline; Malvaux, Ludovic ULg; Bovy, Nicolas ULg et al

in PLoS ONE (2011), 6(2), 16979

BACKGROUND: MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs that regulate gene expression at post-transcriptional level. The recent discovery of the involvement of these RNAs in the ... [more ▼]

BACKGROUND: MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs that regulate gene expression at post-transcriptional level. The recent discovery of the involvement of these RNAs in the control of angiogenesis renders them very attractive in the development of new approaches for restoring the angiogenic balance. Whereas miRNA-21 has been demonstrated to be highly expressed in endothelial cells, the potential function of this miRNA in angiogenesis has never been investigated. METHODOLOGY/PRINCIPAL FINDINGS: We first observed in endothelial cells a negative regulation of miR-21 expression by serum and bFGF, two pro-angiogenic factors. Then using in vitro angiogenic assays, we observed that miR-21 acts as a negative modulator of angiogenesis. miR-21 overexpression reduced endothelial cell proliferation, migration and the ability of these cells to form tubes whereas miR-21 inhibition using a LNA-anti-miR led to opposite effects. Expression of miR-21 in endothelial cells also led to a reduction in the organization of actin into stress fibers, which may explain the decrease in cell migration. Further mechanistic studies showed that miR-21 targets RhoB, as revealed by a decrease in RhoB expression and activity in miR-21 overexpressing cells. RhoB silencing impairs endothelial cell migration and tubulogenesis, thus providing a possible mechanism for miR-21 to inhibit angiogenesis. Finally, the therapeutic potential of miR-21 as an angiogenesis inhibitor was demonstrated in vivo in a mouse model of choroidal neovascularization. CONCLUSIONS/SIGNIFICANCE: Our results identify miR-21 as a new angiogenesis inhibitor and suggest that inhibition of cell migration and tubulogenesis is mediated through repression of RhoB. [less ▲]

Detailed reference viewed: 73 (20 ULg)
Full Text
Peer Reviewed
See detailMicroRNAs in the tumor endothelium: novel controls on the angioregulatory switchboard
Heusschen, Roy ULg; van Gink, Matthijs; Griffioen, Arjan et al

in Biochimica et Biophysica Acta - Reviews on Cancer (2010)

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detailMicroRNAs tune cerebral cortical neurogenesis.
Volvert, M.-L.; Rogister, F.; Moonen, Gustave ULg et al

in Cell Death & Differentiation (2012), 19(10), 1573-81

MicroRNAs (miRNAs) are non-coding RNAs that promote post-transcriptional silencing of genes involved in a wide range of developmental and pathological processes. It is estimated that most protein-coding ... [more ▼]

MicroRNAs (miRNAs) are non-coding RNAs that promote post-transcriptional silencing of genes involved in a wide range of developmental and pathological processes. It is estimated that most protein-coding genes harbor miRNA recognition sequences in their 3' untranslated region and are thus putative targets. While functions of miRNAs have been extensively characterized in various tissues, their multiple contributions to cerebral cortical development are just beginning to be unveiled. This review aims to outline the evidence collected to date demonstrating a role for miRNAs in cerebral corticogenesis with a particular emphasis on pathways that control the birth and maturation of functional excitatory projection neurons. [less ▲]

Detailed reference viewed: 9 (3 ULg)
Full Text
Peer Reviewed
See detailMicrosale interactions between earthworms and microorganisms, a review
Zirbes, Lara ULg; Thonart, Philippe ULg; Haubruge, Eric ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2012), 16(1), 125-131

Detailed reference viewed: 17 (3 ULg)
Peer Reviewed
See detailMicrosatellite Amplification in Plants: Optimization Procedure of Major PCR Components
Ghaffari, Sana; Hasnaoui, Nejib ULg

in Kantartzi, Stella (Ed.) Methods in Molecular Biology™ series: Microsatllites (2013)

Detailed reference viewed: 40 (4 ULg)