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Peer Reviewed
See detailInter-individual differences in night-time cerebral responses to high and low sleep pressure conditions
Maire, Micheline; Reichert, Carolin; Phillips, Christophe ULg et al

Poster (2014)

Detailed reference viewed: 11 (0 ULg)
Peer Reviewed
See detailInter-individual differences in sleep-wake regulation: impact on attention-related cerebral correlates
Schmidt, Christina ULg; Maire, Micheline; Reichert, Carolin et al

Conference (2015)

Detailed reference viewed: 21 (1 ULg)
Peer Reviewed
See detailInter-individual variability in the circadian modulation of sleep spindle duration: a candidate gene approach
Schmidt, Christina ULg; Reichert, Carolin; Maire, Micheline et al

Poster (2013, May)

Detailed reference viewed: 15 (0 ULg)
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See detailInter-individual variability of teachers' feedback: Study in simulated teaching conditions
Cloes, Marc ULg; Denève, Alain; Piéron, Maurice ULg

in European Physical Education Review (1995), 1(1), 83-93

Dans l'enseignement des activités physiques, les réactions de l'enseignant à la prestation des élèves (feedback) constituent l'une des variables déterminantes dans la réussite pédagogique. Les réactions à ... [more ▼]

Dans l'enseignement des activités physiques, les réactions de l'enseignant à la prestation des élèves (feedback) constituent l'une des variables déterminantes dans la réussite pédagogique. Les réactions à la prestation se caractérisent par une grande variabilité interindividuelle. Leur émission fait suite à un processus comportant deux phases: le diagnostic et la prescription. Afin de mettre en évidence le rôle exercé par les facteurs liés aux caractéristiques de l'enseignant sur celles de leurs interventions, nous avons comparé les réactions à la prestation émises par 12 éducateurs physiques lors d'une séance d'enseignement simulé. Grâce à cette technique vidéo, les sujets réagissent à partir de performances motrices identiques. Les feedback ont été comparés entre quatre groupes de sujets caractérisés par des niveaux d'expérience sportive et pédagogique similaires. Une analyse factorielle par correspondance a permis d'identifier des classes de sujets émettant des feedback de même type. Les résultats tendent à souligner que (1) le niveau d'expertise dans la pratique de l'activité enseignée exerce une influence sur la première de ces phases; (2) le degré d'expertise pédagogique contribue à améliorer l'émission du message. [less ▲]

Detailed reference viewed: 98 (4 ULg)
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See detailInter-inidividual variavility in the circadian modulation of sleep spindle duration: a candidate gene approach
Schmidt, Christina ULg; Reichert, Carolin; Maire, Micheline et al

Poster (2013)

Detailed reference viewed: 6 (0 ULg)
Peer Reviewed
See detailInter-laboratory comparison of cytogenetic endpoints for the biomonitoring of radiological workers.
Thierens, H.; Vral, A.; de Ridder, L. et al

in International Journal of Radiation Biology (1999), 75(1), 23-34

PURPOSE: The evaluation of different cytogenetic endpoints of radiation damage for the biomonitoring of contract workers temporarily employed at nuclear power plants. MATERIALS AND METHODS: Blood samples ... [more ▼]

PURPOSE: The evaluation of different cytogenetic endpoints of radiation damage for the biomonitoring of contract workers temporarily employed at nuclear power plants. MATERIALS AND METHODS: Blood samples from six donors were irradiated in vitro with doses ranging from 0.1 to 2Gy 60Co gamma-rays. Compared were a conventional analysis for dicentrics, the conventional micronucleus (MN) assay, the centromere micronucleus assay using p82H and an alphaAllCen pancentromeric probe, and tricolour FISH with chromosome 2, 4 and 8 DNA probes for the scoring of translocations. RESULTS: Agreement in the number of MN between Giemsa-and propidium iodine fluorescence-stained preparations was obtained. The control samples showed higher centromere positivity for the MN after FISH with the p82H probe compared with the alphaAllCen probe. The MN results with both probes showed a slight but systematic increase in the number of centromere-positive MN with dose, indicating that radiation, although principally clastogenic, also has aneuploidogenic properties. The values of the genomic translocation frequency (FG) derived from the observed translocation frequencies were systematically higher than the dicentric yields. Comparing the sensitivity of the different methods with restriction of the scoring time to 1 day for biomonitoring purposes, the centromere micronucleus assay had the lowest dose detection limit (0.1 to 0.2 Gy). CONCLUSION: This study shows that at present only the centromere micronucleus assay can combine high sensitivity with a reasonable scoring time for the biomonitoring of relatively large populations. [less ▲]

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See detailInter-method variability in bone alkaline phosphatase measurement : clinical impact on the management of dialysis patients
CAVALIER, Etienne ULg; Souberbielle, Jean-Claude; GADISSEUR, Romy ULg et al

in Clinical Biochemistry (2014), 47(13-14), 1227-30

BACKGROUND: Bone-specific alkaline phosphatase (BAP) is now recommended to assess bone turnover in hemodialysis (HD) patients. However, little is known about potential variability between methods ... [more ▼]

BACKGROUND: Bone-specific alkaline phosphatase (BAP) is now recommended to assess bone turnover in hemodialysis (HD) patients. However, little is known about potential variability between methods available to measure BAP. METHODS: We measured BAP in 76 HD patients with six different assays (Beckman-Coulter Ostase IRMA, Beckman-Coulter Ostase Access, IDS iSYS Ostase, IDS Ostase enzyme immunoassay, DiaSorin Liaison Ostase and Quidel MicroVue BAP). RESULTS: We observed a high correlation between all the assays ranging from 0.9948 (IDS iSYS vs. IDS EIA) to 0.9215 (DiaSorin Liaison vs. Quidel MicroVue). However, using the regression equations, the equivalent concentration of a Beckman-Coulter Access value of 10μg/L can range from 7.7 to 14.4μg/L and of 20μg/L can range from 16.9 to 27.9μg/L with other assays. According to Beckman-Coulter Access, 13%, 50% and 37% of the patients presented BAP values ≤10, between 10 and 20 and ≥20μg/L, respectively. Discrepancies are observed when other assays are used (concordance from 10 to 100%). CONCLUSIONS: Analytical problems leading to inter-method variation should be overcome to improve the usefulness of this marker in clinical practice. According to correlation results, recalibration of BAP assays is necessary but should not be a major issue. [less ▲]

Detailed reference viewed: 47 (19 ULg)
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See detailInter-modal freight terminal location in Europe : a strategic model
Jourquin, Bart; Limbourg, Sabine ULg

in Proceedings of the BIVEC-GIBET, Transport Research Day 2007 (2007)

The political pressure in favour of multi- and inter-modal transport has oriented the focus on sustainable transport solutions. Inter-modal transport is one of the possible solutions, but its efficiency ... [more ▼]

The political pressure in favour of multi- and inter-modal transport has oriented the focus on sustainable transport solutions. Inter-modal transport is one of the possible solutions, but its efficiency strongly depends on the places where the container terminals are located. The number of possible locations on large scale networks becomes rapidly too large to be taken as input by exact location methods. That’s why the first goal of this paper is to outline a method that helps to identify the best potential locations out of the thousands of potential nodes. The basic idea is to use the flows of commodities and their geographic spreading as input to determine a set of good potential locations for transfer inter-modal terminals. This set can, in a second step, be used as input for already well known optimal location models in order to identify the optimal locations for container terminals in Europe. The methodology is illustrated over the whole trans-European networks. The paper concludes with a discussion of the results: the model predicts a reduction of the total transportation costs on the network and a modal shift from road to rail. It also evaluates the new modal shift and other indicators [less ▲]

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See detailInter-modal freight terminal location in Europe: a strategic model
Limbourg, Sabine ULg

Conference (2006)

The political pressure in favour of multi- and inter-modal transport has oriented the focus on sustainable transport solutions. Inter-modal transport is one of the (partial) possible solutions, but its ... [more ▼]

The political pressure in favour of multi- and inter-modal transport has oriented the focus on sustainable transport solutions. Inter-modal transport is one of the (partial) possible solutions, but its efficiency strongly depends on the places where the container terminals are located. The number of possible locations on large scale networks such as the European one becomes rapidly too large to be taken as input by exact location methods. That’s why the first goal of this paper is to outline a method that helps to identify the best potential locations out of the thousands of potential nodes. The basic idea is to use the flows of commodities and their geographic spreading as input to determine a set of good potential locations for transfer inter-modal terminals. This set can, in a second step, be used as input for already well known optimal location models in order to identify the optimal locations for container terminals in Europe. The complete methodology is illustrated by means on a case study that concerns multi-modal transport over the whole trans-European networks. [less ▲]

Detailed reference viewed: 51 (4 ULg)
See detailInter-modal freight terminals location: Discover the best potential locations on large networks
Limbourg, Sabine ULg; Jourquin, Bart

Conference (2005)

The optimal location of a facility is a rather complex task that was already studied many times. Several optimal location problems and solution exists, but only a few can be applied to the location of ... [more ▼]

The optimal location of a facility is a rather complex task that was already studied many times. Several optimal location problems and solution exists, but only a few can be applied to the location of multimodal freight terminals. Among the possible approaches, if theoretical solutions can be found in the literature, the computational complexity of the proposed methods make them impossible to be applied to real world large geographical networks. Indeed, many of them are based on linear programming, for which the number of constraints drastically increases with the number of terminals to take into account. This paper identifies the possible existing theoretical exact solutions and the framework of a new approach, in which the initial set of potential terminals is computed by means of the results obtained by the assignment of the flows of commodities on the trans-European network [less ▲]

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See detailInter-Modal Terminals for Freight
Limbourg, Sabine ULg; Jourquin, Bart

Conference (2005)

The optimal location of terminals and logistic centres is an up-to-date research topic. The first goal of this paper is to outline a method that helps to isolate the best potential locations. The basic ... [more ▼]

The optimal location of terminals and logistic centres is an up-to-date research topic. The first goal of this paper is to outline a method that helps to isolate the best potential locations. The basic idea is to use the flows of commodities and their geographic spreading as input to determine a set of good potential locations for inter-modal terminals on the trans-European networks. This set can then be used in conjunction with already known optimal location models. Some approaches to solve the optimal location problems will be briefly presented. After that, the method used to obtain a detailed O-D matrix for European international freight traffic will be outlined, in addition to a short explanation on the way the demand can be assigned on a multi-modal freight transportation network. The assigned flow will be used as input to compute a set of potential locations. [less ▲]

Detailed reference viewed: 15 (2 ULg)
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Peer Reviewed
See detailInter-observer variation in the histopathological diagnosis of clinically suspicious pigmented skin lesions.
Brochez, Lieve; Verhaeghe, Evelien; Grosshans, Edouard et al

in Journal of Pathology (The) (2002), 196(4), 459-66

When a biopsy is taken of a suspicious pigmented skin lesion, histological examination is expected to establish the definitive diagnosis. This study evaluated the inter-observer variation of 20 ... [more ▼]

When a biopsy is taken of a suspicious pigmented skin lesion, histological examination is expected to establish the definitive diagnosis. This study evaluated the inter-observer variation of 20 pathologists in the histological diagnosis of a randomly selected set of suspicious pigmented skin lesions (PSLs), by comparing their diagnoses to a reference diagnosis. Overall sensitivity for melanoma was 87%, ranging from 55% to 100% between the observers. Sensitivity was significantly lower for thin (Breslow thickness <1 mm) than for thick melanomas (83% versus 97%, p=0.005). Overall melanoma specificity was 94%, ranging from 83% to 100% between observers. Dysplastic naevus was the most important source of false-positive diagnoses, mainly in situ melanomas. Positive and negative predictive values in the given test set were 75% and 97%, respectively. In the case of melanoma, there was quite some variation in measured Breslow thickness. This would have led to a different therapeutic approach in 12% of the readings. Some of the variation seemed to be due to a different interpretation of the presence of a co-existent naevus. In 9% (3/35) of the readings, participants did not agree on the presence of ulceration. These results reflect a tendency to overdiagnose mainly thin melanomas in general histopathological practice. They also demonstrate variation in the assessment of major prognostic factors of melanoma. [less ▲]

Detailed reference viewed: 41 (0 ULg)
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See detailInter-organizational innovation projects developed within the framework of a public policy - Discussion and observations about the nature of innovations, cooperation practices and their interrelationships
Antoine, Mélanie ULg

Conference (2008, May)

In recent years, the promotion of R&D partnerships between universities, research labs and companies has become a key feature of innovation and development public policies. However, these collaborations ... [more ▼]

In recent years, the promotion of R&D partnerships between universities, research labs and companies has become a key feature of innovation and development public policies. However, these collaborations turn out to be fragile and their management very complex. In our literature review, the congruence between the nature of innovations (i.e. their radicalness) and the cooperation practices appears as a potentially powerful explanatory factor of interfirm innovation project’s outcome. Following this hypothesis, we explore, on two case studies of projects subsidized by the Walloon Competitive Clusters program, the way actors innovate and organize their actions. Though they face similar constraints, these projects illustrate diverse configurations, not only as to the nature of innovations but also as to cooperation practices. Besides, the analysis reveals that the criteria used to characterize the nature of innovations do not necessarily form a homogeneous set of factors. Considering these observations, we try to identify the main challenges faced by both projects’ partners. [less ▲]

Detailed reference viewed: 39 (2 ULg)
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Peer Reviewed
See detailInter-organizational learning within innovation projects : critical stages, issues and good practices
Rondeaux, Giseline ULg; Chalant, Ingrid ULg; Degré, Julie ULg et al

Conference (2009, October 13)

In September 2005, the Walloon Government decided to adopt “the Walloon Marshall Plan”, one of the priorities of which is the setting up of competitiveness clusters bringing together different ... [more ▼]

In September 2005, the Walloon Government decided to adopt “the Walloon Marshall Plan”, one of the priorities of which is the setting up of competitiveness clusters bringing together different contributors (businesses, private & public research centres and training centres). In this context, our aim is to understand how the businesses and the research and training centres are managing to put in place partnership dynamics in order to create innovative projects. To achieve this, we have chosen to focus primarily on the dynamics of inter-organizational learning. Consequently, within the five competitiveness clusters set up in mid-2006, we have opted to focus in particular on 4 projects which have emerged from them. The conceptual model upon which we have based our initiative is structured around this aim and makes use of various analytical benchmarks. Inspired in particular by the work of Holmqvist (2003), this model constitutes our reading and analysis framework for the projects selected from the four competitiveness clusters selected. [less ▲]

Detailed reference viewed: 82 (11 ULg)
Peer Reviewed
See detailInter-professional cooperation between family, occupational and social insurance physicians in managing long-term sickness absence
Mairiaux, Philippe ULg; Vanmeerbeek, Marc ULg; Schippers, Nathalie ULg et al

Conference (2014, September 30)

Background In the Belgian health system, sickness absence (SA) management implies complementary roles for general practitioners (GPs), social insurance physicians (SIPs) and occupational physicians (OPs ... [more ▼]

Background In the Belgian health system, sickness absence (SA) management implies complementary roles for general practitioners (GPs), social insurance physicians (SIPs) and occupational physicians (OPs): GPs deliver sick notes and treatment, SIPs control SA benefits and OPs strive to adapt work environments to workers’ remaining capacities. In practice however, there is little cooperation between the three physicians. In 2009, the Ministry of Employment commissioned a study to identify GP-OP-SIP cooperation channels in order to prevent long-term work disability. Methods The study involved two phases. 1) Researchers from the three groups agreed on 15 proposals to enhance cooperation: to establish a formal contact between GP, SIP and OP for patients with > 3 months SA (n=3) ; SIP decision to end SA benefit to be forwarded to the GP (n=2) ; work-related information to be provided by the OP to GP and/or SIP (n=4); website giving contact data of GPs, SIPs, and OPs (n=2) ; initial and continuous education focusing on inter-physician cooperation (n=3); electronic data exchange when dealing with long-term SA (n=1). 2) A Delphi study was conducted in 2012 to validate these proposals: 61 experts representing professional groups of physicians (GP, SIP, OP), patients, government, employers and labor unions were asked to participate. A 18-items questionnaire (the 15 proposals and 3 open questions) was used in a 2-round Delphi study. Proposals were accepted if 80% of experts agreed. For drafting the final proposals, the research team relied on a multidisciplinary expert group. Results Participation rate was 77% (47/61 experts) in round 1 and 7 out of the 15 proposals were accepted. During round 2, participation rate was 94% (44/47); 2 of the remaining proposals reached agreement level. Public authorities were thus advised to invest in a) promotion of pre-return to work visit with the OP for sick-listed patients; b) a website with OPs contact data; c) joint guidelines for return to work guidance; d) joint training of the 3 physician groups; 5) methods ensuring safe electronic information exchange. Conclusions The need for inter-physician cooperation in disability management may exceed individual goodwill and should best be organised by public authorities. The current study may be a first step in this process. [less ▲]

Detailed reference viewed: 49 (11 ULg)