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See detailLocalisation of the phosphoester bond hydrolyzed by the major apurinic/apyrimidinic endodeoxyribonuclease from rat-liver chromatin.
Verly, Walter G; Colson, Pierre ULg; Zocchi, Germaine ULg et al

in European Journal of Biochemistry (1981), 118

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See detailLocalisation optimale de hubs de conteneurs à l’aide d’un modèle de réseau
Limbourg, Sabine ULg

Scientific conference (2008)

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See detailLocalisation respiratoire d'un lymphosarcome cutané chez un cheval.
Anciaux, Nathalie; Amory, Hélène ULg

in Pratique Vétérinaire Equine (1996), 28

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See detailLocalisation scintigraphique de tumeurs neuroendocrines et de leurs métastases par un analogue de la somatostatine: [111In-DTPA-d-phe1] octreotide
Beckers, Albert ULg; Pham, V. T.; Abs, R. et al

in Médecine & Chirurgie Digestives (1994), 23(3), 145-150

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See detailLocalisation scintigraphique de tumeurs neuroendocrines et de leurs métastases par un analogue de la somatostatine: [111In-DTPA-d-phe1] octréotide.
Beckers, Albert ULg; Pham, V. T.; Abs, R. et al

in Revue Médicale de Liège (1993), 48(6), 326-34

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See detailLocalisation spatiotemporelle du cytosquelette dans les cellules du canal cochléaire chez le rat entre le 18e jour embryonnaire et le 15e jour postnatal
Johnen, Nicolas ULg

Master's dissertation (2009)

L’organe de l’audition chez les mammifères est sans doute l’une des plus remarquables structures rencontrées chez les vertébrés supérieurs. Cet organe, qui porte le nom de celui qui l’a décrit pour la ... [more ▼]

L’organe de l’audition chez les mammifères est sans doute l’une des plus remarquables structures rencontrées chez les vertébrés supérieurs. Cet organe, qui porte le nom de celui qui l’a décrit pour la première fois à la moitié du XIXème siècle (Alfonso Corti, 1851), possède un arrangement cellulaire complexe et hautement ordonné. L’organe de Corti est situé sur la face dorsale du canal cochléaire, au sein de l’oreille interne. Il est composé de cellules sensorielles reposant sur des cellules de soutien. Trois rangées de cellules sensorielles externes et une rangée de cellules sensorielles internes sont réparties de part et d’autre du tunnel de Corti, lui-même limité par les cellules piliers externes et internes. Chaque cellule sensorielle est séparée de la suivante par une cellule de soutien, les cellules de Deiters du côté externe et les cellules phalangeaires du côté interne. À l’état mature, cette structure est bien connue ; cependant, notre connaissance de la mise en place du cytosquelette dans ces différentes cellules hautement spécialisées de l’organe de l’audition en développement reste largement parcellaire et incomplète. Dans ce mémoire, nous avons analysé en microscopie confocale à balayage laser le développement de l’organe de Corti entre le 18e jour embryonnaire et le 15e jour post-natal. Pour appréhender le cytosquelette, nous avons utilisé les anticorps anti-tubuline βIV, anti-vimentine, anti-cytokératine pan (CK 1, 4, 5, 6, 8, 10, 13, 18 et 19), et anti-cytokératine 8. Seule la partie basale du canal cochléaire et les structures adjacentes ont été examinées. Nous observons que la tubuline βIV est présente au niveau des cellules sensorielles internes entre E21 et P4-P5, au niveau des cellules sensorielles externes entre P0 et P4-P5, de la cellule phalangeaire à P0, au niveau de la cellule pilier interne et au niveau des cellules de Deiters entre P0 et P15 et enfin au niveau de la cellule pilier externe entre P4-P5 et P15 ; ainsi, cette protéine est d’abord présente dans les cellules sensorielles et ensuite dans les cellules de soutien. Enfin, nous montrons pour la première fois que la cellule phalangeaire est marquée à P0 avec cet anticorps. Nous décelons également une positivité dans toutes les cellules épithéliales du canal cochléaire, et en particulier au niveau des cellules piliers et au niveau des cellules de Deiters entre P8 et P12, avec les deux anticorps anti-cytokératine utilisés. Nous localisons de la vimentine au sein de l’épithélium du canal cochléaire alors que celle-ci est typique des cellules d’origine mésodermique. Cette transition épithélio-mésenchymateuse permettrait aux cellules épithéliales d’acquérir une plus grande liberté de mouvement. Finalement, nous suggérons que les marquages préférentiels des cellules piliers et des cellules de Deiters entre P8 et P12 obtenus avec les quatre anticorps étudiés pourraient être corrélés avec la formation du tunnel de Corti et des espaces de Nuel dans l’organe de l’audition. [less ▲]

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See detaillocalisation transmembranaire du transporteur mitochondrial présumé RIM2 de Saccharomyces Cerevisiae
Elmoualij, Benaïssa ULg

Master of advanced studies dissertation (1994)

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See detailLocalisation ultrastructurale d'hormones hypophysaires par reaction immunocytochimique sur coupes fines d'adenomes.
Beckers, Albert ULg; Courtoy, R.; Reznik, Michel ULg et al

in Comptes Rendus des Séances de la Société de Biologie et de ses Filiales (1985), 179(3), 397-402

Human pituitary adenomas were fixed in glutaraldehyde and embedded in epon. Ultrathin sections were incubated either with anti-hGH, anti-hPRL or anti-hLH. They were incubated with second step goat anti ... [more ▼]

Human pituitary adenomas were fixed in glutaraldehyde and embedded in epon. Ultrathin sections were incubated either with anti-hGH, anti-hPRL or anti-hLH. They were incubated with second step goat anti-rabbit immunoglobulins linked to gold particles. Two PRL secreting adenomas, one GH and PRL secreting adenoma, one ACTH secreting adenoma and two non secreting adenomas were studied. The specificity and the limits of the method were discussed in relation with the results obtained in light microscopy with the PAP method. [less ▲]

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See detailLocalisation ultrastructurale du rDNA et du rRNA dans le nucléole
Thiry, Marc ULg

Scientific conference (1991)

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See detailLocalisations industrielles et milieu urbain
Merenne-Schoumaker, Bernadette ULg

in Bulletin de la Société Géographique de Liège (1977), (13), 5-18

The report first analyses the causes and consequences of the recent de-urbanisation of industrial activities. On account of the problems created by this movement, the survey then puts forward new ... [more ▼]

The report first analyses the causes and consequences of the recent de-urbanisation of industrial activities. On account of the problems created by this movement, the survey then puts forward new solutions that aim for a better integration of industrial concerns. These proposals deal mainly with the types of industries that should be maintained or established as well as the terms and conditions of integration. In this connection, it seems impera¬tive to work out a new planning policy for urban space where the renovated secondary sector would find its place due to new formulas such as vertical industrial structures, individual buildings with an urbanised facade and small industrial estates. [less ▲]

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See detailLocalizable effective theories, bootstrap and the parameters of hadron resonances
Semenov-Tyan-Shanskiy, Kirill ULg; Vereshagin, Alexander; Vereshagin, Vladimir

in AIP Conference Proceedings (2004), 717

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See detailLocalization and Controls of Aromatase in the Quail Spinal Cord
Evrard, H.; Baillien, M.; Foidart, Agnès ULg et al

in Journal of Comparative Neurology (The) (2000), 423(4), 552-64

In adult male and female Japanese quail, aromatase-immunoreactive cells were identified in the spinal dorsal horns from the upper cervical segments to the lower caudal area. These immunoreactive cells are ... [more ▼]

In adult male and female Japanese quail, aromatase-immunoreactive cells were identified in the spinal dorsal horns from the upper cervical segments to the lower caudal area. These immunoreactive cells are located mostly in laminae I-III, with additional sparse cells being present in the medial part of lamina V and, at the cervical level exclusively, in lamina X around the central canal. Radioenzyme assays based on the measurement of tritiated water release confirmed the presence of substantial levels of aromatase activity throughout the rostrocaudal extent of the spinal cord. Contrary to what is observed in the brain, this enzyme activity and the number of aromatase-immunoreactive cells in five representative segments of the spinal cord are not different in sexually mature males or females and are not influenced in males by castration with or without testosterone treatment. The aromatase activity and the numbers of aromatase-immunoreactive cells per section are higher at the brachial and thoracic levels than in the cervical and lumbar segments. These experiments demonstrate for the first time the presence of local estrogen production in the spinal cord of a higher vertebrate. This production was localized in the sensory fields of the dorsal horn, where estrogen receptors have been identified previously in several avian and mammalian species, suggesting an implication of aromatase in the modulation of sensory (particularly nociceptive) processes. [less ▲]

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See detailLocalization and latency concepts applied to time simulation of large power systems
Fabozzi, Davide ULg; Van Cutsem, Thierry ULg

in Proceedings of the 2010 IREP Symposium (2010, August)

This paper reports on investigations to speed up time domain simulations of large electric power systems. First, a decomposed scheme is considered which exploits the bordered block diagonal structure of ... [more ▼]

This paper reports on investigations to speed up time domain simulations of large electric power systems. First, a decomposed scheme is considered which exploits the bordered block diagonal structure of the original Jacobian involved in the Newton iterations, and keeps the resulting “local” Jacobians constant over multiple iterations. Next, a localization technique is considered, allowing to perform less iterations on the system components with lower activity. Finally, a third scheme consists of visiting only a subset of components, identified as active, and skipping the other ones, identified as latent. The first two techniques solve the whole set of equations with the required accuracy, while the third one involves an adjustable degree of approximation. The methods are illustrated on a small system, while preliminary checks of computational savings from a large test system are reported. Additional results deal with the application of the localization and latency techniques to simplified simulation of the detailed model. [less ▲]

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See detailLocalization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines
Fuks, Bruno; Gillard, Michel; Michel, Philippe et al

in European Journal of Pharmacology (2003), 478(1), 11-19

Levetiracetam (2S-(2-oxo-1-pyrrolidinyl)butanamide, KEPPRA(R)), a novel antiepileptic drug, has been shown to bind to a specific binding site located in the brain (Eur. J. Pharmacol. 286 (1995) 137). To ... [more ▼]

Levetiracetam (2S-(2-oxo-1-pyrrolidinyl)butanamide, KEPPRA(R)), a novel antiepileptic drug, has been shown to bind to a specific binding site located in the brain (Eur. J. Pharmacol. 286 (1995) 137). To identify the protein constituent of the levetiracetam binding site in situ, we synthesized the photoaffinity label [H-3]ucb 30889 ((2S)-2-[4-(3-azidophenyl)-2-oxopyrrolidin-1-yl]butanamide), a levetiracetam analog with higher affinity for the levetiracetam binding site. This radioligand was used to map the levetiracetam binding site within the brain and to study its cellular and subcellular distribution. Autoradiography experiments using [H-3]ucb 30889 in rat brain revealed a unique distribution profile that did not match that of classical receptors known to be involved in the generation of epileptic seizures. There was a high level of binding in the dentate gyrus, the superior colliculus, several thalamic nuclei, the molecular layer of the cerebellum and to a lesser extent in the cerebral cortex, the striatum and the hypothalamus. The levetiracetam binding site was restricted to neuronal cell types, undifferentiated PC 12 cells and was highly enriched in synaptic vesicles. [H-3]ucb 30889 was also used in photoaffinity labelling studies and shown to bind covalently to a membrane protein with a molecular weight of approximately 90 kDa. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailLocalization and quantification of damage in beam-like structures using sensitivities of principal component analysis results
Nguyen, Viet Ha ULg; Golinval, Jean-Claude ULg

in Mechanical Systems & Signal Processing (2010), 24(6), 1831-1843

Principal component analysis (PCA) is known as an efficient method for dynamic system identification and diagnosis. This paper addresses a damage diagnosis method based on sensitivities of PCA in the ... [more ▼]

Principal component analysis (PCA) is known as an efficient method for dynamic system identification and diagnosis. This paper addresses a damage diagnosis method based on sensitivities of PCA in the frequency domain for linear-form structures. The aim is not only to detect the presence of damage, but also to localize and to evaluate it. The Frequency response functions measured at different locations on the beam are considered as data for the PCA process. Sensitivities of principal components obtained from PCA to beam parameters are computed and inspected according to the location of sensors; their variation from the healthy state to the damaged state indicates damage locations. The damage can be evaluated next providing that a structural model is available; this evaluation is based on a model updating procedure. It is worth noting that the diagnosis process does not require a modal identification achievement. Both numerical and experimental examples are used for better illustration. [less ▲]

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See detailLocalization and transmembrane topology of a new member of the mitochondrial carrier family, the yeast RIM 2 gene product
Elmoualij, Benaïssa ULg; Duyckaerts, Claire ULg; Lamotte-Brasseur, J. et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1995)

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See detailLocalization by immunofluorescent microscopy of several collagen types and of a basement membrane proteoglycan in rat glomerular epithelial and mesangial cell cultures.
Foidart, J. B.; Foidart, Jean-Michel ULg; Hassell, J. et al

in Renal Physiology (1983), 6(4), 163-70

Confluent cultures of rat glomerular epithelial and mesangial cells were studied by immunofluorescent microscopy, using affinity-purified antibodies directed against collagen of type I-V or an antiserum ... [more ▼]

Confluent cultures of rat glomerular epithelial and mesangial cells were studied by immunofluorescent microscopy, using affinity-purified antibodies directed against collagen of type I-V or an antiserum directed against a basement membrane (BM) proteoglycan. The epithelial cells were stained by antibodies directed against type I, IV and V collagen, whereas the mesangial cells were stained by all the antibodies directed against the different collagenous antigens tested. Therefore, only mesangial cells contained antigenic determinants of type III collagen. On the contrary, both cell types possessed BM proteoglycan antigens. The data suggest that rat glomerular epithelial and mesangial cells may be implicated in the biosynthesis of different components of normal (and pathological) glomerular BM. [less ▲]

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See detailLocalization of DNA in nucleoli with and without fibrillar centers
Thiry, Marc ULg

Conference (1998)

Detailed reference viewed: 4 (0 ULg)