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See detailL'innovation technologique, entre mythes et réalités
Halleux, Robert ULg; Peters, Arnaud ULg

in Ecomusée du Bois du Luc (Ed.) Itinéraire de la Culture Industrielle. Carnet d'exploration (2011)

Detailed reference viewed: 97 (16 ULg)
See detailL'innovation, entre rhétorique et réalité
Peters, Arnaud ULg; Halleux, Robert ULg

Book published by En Poche (Académie-Editions) (2016)

Detailed reference viewed: 13 (5 ULg)
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See detailLes innovations apportées par la loi du 8 juin 2008 à la correctionnalisation des crimes et à la contraventionnalisation des délits
Michiels, Olivier ULg; Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2008), n° 32

L'article analyse les innovations apportées par la loi du 8 juin 2008 à la correctionnalisation des crimes et à la contraventionnalisation des délits

Detailed reference viewed: 456 (28 ULg)
See detailLes innovations dans l'intervention sociale et la justice des mineurs en Belgique
Born, Michel ULg

in Revue Internationale de Criminologie et de Police Technique (1991), 4

Detailed reference viewed: 11 (2 ULg)
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See detailInnovations in IT Organization Design: Is the Public Sector Really a Special Case?
Markus, M. Lynne; Jacobson, Dax D.; Lisein, Olivier ULg et al

E-print/Working paper (2013)

IT organization design, consisting of IT governance (decision rights) and IT organization structure, is believed to affect organizational performance. This paper describes the IT organization design ... [more ▼]

IT organization design, consisting of IT governance (decision rights) and IT organization structure, is believed to affect organizational performance. This paper describes the IT organization design choices of the 50 U.S. state governments. Significant movement toward greater centralization was observed (particularly for IT services). States appeared to have adopted IT organization design innovations previously pioneered in the private sector, contrary to conventional wisdom founded on well-documented differences between the two sectors. Two commonly used explanations of IT organization design choices were examined for their ability to account for the unexpected findings — contingency and institutional theories. Both explanations were partially successful in explaining the results, but further theoretical development is needed to integrate those theories and more empirical research is needed to advance the field’s knowledge of IT organization design. [less ▲]

Detailed reference viewed: 137 (20 ULg)
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See detailInnovations in Navigation Lock Design
Rigo, Philippe ULg

in IWASA - 40th Intern Symp on Hydraulic Engineering (2010, January)

LOCK - Inovations

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See detailInnovations in Navigation Lock Design
Rigo, Philippe ULg; INCOM WG26

in International Navigation Seminar, PIANC AGA2008, Beijing, China Communication Press (CIP), Beijing, China (2008, May)

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See detailInnovations in Navigation Lock Design
Rigo, Philippe ULg; Members of PIANC INCOM WG29

in 32nd PIANC Congress – Liverpool UK – 10-14 May 2010 (2010, May)

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See detailInnovations in Navigation Lock Design
Rigo, Philippe ULg; INCOM WG29

Book published by PIANC - Report 106 - 2009 (2009)

State of art in navigation locks , focuss on innovations

Detailed reference viewed: 520 (53 ULg)
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See detailInnovations in software packages in quantitative genetics
Druet, Tom ULg; Ducrocq, V.

in Proceedings of the 8th World Congress on Genetics Applied to Livestock Production (2006)

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See detailInnovations pédagogiques et utiliation des NTIC dans le cadre de la formulation des aliments complets
Malumba Kamba, Paul ULg; Masimango, Thaddée

in Kechaou, Mohamed (Ed.) Actes du séminaire régional sur les Technologies douces et procédés de séparation au service de la qualité et de l'innocuité des aliments ’ (2006, November 27)

Des nombreuses approches d’optimisation des formulations ont été développées ces dernières années et commercialisées sous forme de logiciels dont les bases d’application restent méconnues de nombreux ... [more ▼]

Des nombreuses approches d’optimisation des formulations ont été développées ces dernières années et commercialisées sous forme de logiciels dont les bases d’application restent méconnues de nombreux praticiens. Dans la présente étude des fondements de la formulation conceptuelle des aliments utilisant les NTIC sont présentés et appliqués à un cas de formulation d’un aliment de croissance pour pondeuse. La validation de la formulation conceptuelle est obtenue grâce à l’analyse de la composition d’un aliment réel préparé suivant le modèle défini. Cet aliment est comparé avec un aliment équivalent de commerce [less ▲]

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See detailInnovations technologiques en radiothérapie-oncologie
Coucke, Philippe ULg; Louis, Céline ULg; Bolle, Stéphanie

in Revue Médicale de Liège (2007), 62 (5-6)

InnovatIve technologIes In radIatIon oncology SUMMARY : At present, radiation oncology is again flourishing thanks to the development of highly accurate techniques as intensity modulated radiation therapy ... [more ▼]

InnovatIve technologIes In radIatIon oncology SUMMARY : At present, radiation oncology is again flourishing thanks to the development of highly accurate techniques as intensity modulated radiation therapy, stereotactic radiation therapy and hadrontherapy. These therapeutic modalities are made possible by the advent of image guided radiation therapy and respiratory gating that allows a better patient repositioning during the irradiation and between fractions. Nowadays, thanks to these recent technological advances, one can more easily conceive dose escalation, hypofractionation and combined treatment of radiation with sensitizing drugs and this together with a better protection of normal tissue aiming at, simultaneously, improved tumour control and better quality of life. This article describes these innovative technologies that, when integrated to other anti-tumoral therapeutic modalities, seem to be very promising. Keywords : - [less ▲]

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See detailInnovative algorithms to combine phenotypic, genealogical and genomic information originating from diverse sources
Vandenplas, Jérémie ULg

Doctoral thesis (2014)

Along with technical developments, international exchanges of genetic material (e.g., frozen semen, embryos) have increased since the 1970s. However, genetic evaluations are traditionally based on ... [more ▼]

Along with technical developments, international exchanges of genetic material (e.g., frozen semen, embryos) have increased since the 1970s. However, genetic evaluations are traditionally based on phenotypic and genealogical data which are internally recorded, i.e., within well defined borders. Because imported (i.e., external) genetic material is usually strongly selected in their respective populations, internal genetic evaluations for external animals could be biased and less accurate if external data used for their selection is ignored. Moreover, comparison of internal and external animals based on their internal and external estimates of genetic merit is needed to select and potentially import the most suitable ones according to the internal breeding goal. However, such comparison is usually not possible among internal and external genetic evaluations due, e.g., to differences among units of measurement. Thereby, several approaches and algorithms have been developed to render internal and external genetic evaluations comparable, and to combine or blend phenotypic and genealogical data and external information, i.e., estimates of genetic merit and associated reliabilities. Furthermore, the recent development of genomic selection also increased needs for combining phenotypic, genealogical and genomic data and information. Therefore, the aim of this thesis was first to develop innovative algorithms to combine diverse sources of phenotypic, genealogical and genomic data and information, and second to test them on simulated and real data in order to check their correctness. Based on a Bayesian view of the linear mixed models and addressing several issues highlighted by previous studies, systems of equations combining simultaneously diverse sources of data and external information were developed for (multivariate) genetic and single-step genomic evaluations. Double counting of contributions due to relationships and due to records were considered as well as computational burden. The performances of the developed systems of equations were evaluated using simulated datasets and real datasets originating from genetic (genomic) evaluations for Holstein cattle and for show jumping horses. The different results showed that the developed equations integrated and blended several sources of information in a proper way into a genetic or a single-step genomic evaluation.It was also observed that double counting of contributions due to relationships and due to records was (almost) avoided. Furthermore, more reliable estimates of genetic merit were also obtained for external animals and for their relatives after integration of external information. Also, the developed equations can be easily adapted to complex models, such as multivariate mixed models. Indeed, it was shown that external information correlated to the internal phenotypic traits was properly integrated using the developed equations. Finally, research of this thesis led to the development of a genomic evaluation system for Holstein cattle in the Walloon Region of Belgium for production traits, as well as for other traits, like somatic cell score. Based on the research of this thesis, future research topics, e.g., concerning integration of correlated external information and of genomic information, were finally presented. [less ▲]

Detailed reference viewed: 92 (33 ULg)
See detailInnovative analytical strategies for small molecules analysis by ion-mobility mass spectrometry
Eppe, Gauthier ULg; Goscinny, Séverine; Far, Johann ULg et al

Conference (2014, January)

Detailed reference viewed: 46 (16 ULg)
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See detailInnovative analytical strategy using ion-mobility for structural or functional selenium isomers identification by ion mobility spectrometry
Far, Johann ULg; Kune, Christopher ULg; Lobinski, Ryszard et al

Poster (2013, July)

Selenium (Se) is a trace element which is both essential and toxic depending on its concentration and its chemical form. Se-rich yeast is one of the most popular Se source for supplementation. The ... [more ▼]

Selenium (Se) is a trace element which is both essential and toxic depending on its concentration and its chemical form. Se-rich yeast is one of the most popular Se source for supplementation. The classical method of speciation is related to multidimensional liquid chromatography (LC) hyphenated to mass spectrometry (MS) Recent advances in Se speciation led to greatly improve the Se speciation in these samples but isomers identification and quantification remain challenging. This work focuses on the elaboration of an innovative analytical strategy for the detection and the structural elucidation of isobaric selenium compounds present in Se-rich yeast. A specific complex formation agent acts as a chemical probe for the detection of chemical function. The addition of a complexing agent can improve the discrimination between structural or functional Se isomers using ion mobility techniques as Ion Mobility Spectrometry (IMS) by increasing the molecular weight (i.e. the m/z ratio in MS) and the collision cross section of a target ion after selective complexation. This Ion Mobility orthogonal separation improves the structural elucidation. Crown ethers used as shifting agents can specifically form complexes with primary amines. The addition of crown ether to different low molecular weight fractions obtained by multidimensional LC of a water extract from Se-rich yeast permitted to detect Se isomers and confirmed their structure using IMS. [less ▲]

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See detailInnovative analytical strategy using ion-mobility shifting additive for isobaric selenium compound identification in selenomethionine standards by IMS
Kune, Christopher ULg; Far, Johann ULg; Eppe, Gauthier ULg et al

Conference (2013, July 09)

Selenium (Se) is a trace element which is both essential and toxic depending on its concentration and its chemical form. Selenomethionine (SeMet) is one of the widely used selenium standard during ... [more ▼]

Selenium (Se) is a trace element which is both essential and toxic depending on its concentration and its chemical form. Selenomethionine (SeMet) is one of the widely used selenium standard during Selenium speciation studies. This work was focused on the elaboration of an analytical strategy for the detection and the structural elucidation of an isobaric Se interference, which is found in standard solutions of SeMet by high resolution mass spectrometry (Rm/Δm > 20.000). The structural elucidation of these compounds requires the isolation of the respective parent ion. Nevertheless, the mass difference between SeMet and its interference is less than 0.02Da which is well below the window selection of conventional techniques in mass spectrometry (Quadripole, ion trap). The empirical formula and double bound equivalent (DBE) of these ions suggest different tridimensional structures which lead to a discrimination depending on the ion mobility. This separation is observed, both in gaseous and liquid phase, by Ion Mobility Spectrometry (IMS), Capillary Electrophoresis (CE) and Liquid Chromatography (LC) which are hyphenated to mass spectrometry as detector. The separation efficiency of these ions by IMS and CE is improved by using specific shifting agents (18-Crown-6 Ether) selective to only one of these ions. This strategy has successfully separated the two isobaric ions present and leads to the structural elucidation of the isobar contaminant of SeMet. [less ▲]

Detailed reference viewed: 55 (28 ULg)