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See detailLocal control of non-adiabatic dissociation dynamics
Bomble, Laëtitia; Chenel, Aurélie; Meier, Chris et al

in Journal of Chemical Physics (2011), 134

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See detailLocal control of nonadiabatic photodissociation dynamics using Møller operators
Vranckx, Stéphane; Meier, Christoph; Bomble, Laetitia et al

in Journal of Physics: Conference Series (2012), 388(11), 112009

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See detailLocal Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution.
Dhulesia, A.; Cremades, N.; Kumita, J. R. et al

in Journal of the American Chemical Society (2010)

The partial unfolding of human lysozyme underlies its conversion from the soluble state into amyloid fibrils observed in a fatal hereditary form of systemic amyloidosis. To understand the molecular ... [more ▼]

The partial unfolding of human lysozyme underlies its conversion from the soluble state into amyloid fibrils observed in a fatal hereditary form of systemic amyloidosis. To understand the molecular origins of the disease, it is critical to characterize the structural and physicochemical properties of the amyloidogenic states of the protein. Here we provide a high-resolution view of the unfolding process at low pH for three different lysozyme variants, the wild-type protein and the mutants I56T and I59T, which show variable stabilities and propensities to aggregate in vitro. Using a range of biophysical techniques that includes differential scanning calorimetry and nuclear magnetic resonance spectroscopy, we demonstrate that thermal unfolding under amyloidogenic solution conditions involves a cooperative loss of native tertiary structure, followed by progressive unfolding of a compact, molten globule-like denatured state ensemble as the temperature is increased. The width of the temperature window over which the denatured ensemble progressively unfolds correlates with the relative amyloidogenicity and stability of these variants, and the region of lysozyme that unfolds first maps to that which forms the core of the amyloid fibrils formed under similar conditions. Together, these results present a coherent picture at atomic resolution of the initial events underlying amyloid formation by a globular protein. [less ▲]

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See detailLocal coordination between levels of care: opportunities and threats
Belche, Jean-Luc ULg; Duchesnes, Christiane ULg; Van der Vennet, Jean et al

Conference (2012, October 20)

Background: Coordination between levels of care is not compulsory in the Belgian health system. Patients have direct access to specialists. Hence, competition between professionals and fragmentation of ... [more ▼]

Background: Coordination between levels of care is not compulsory in the Belgian health system. Patients have direct access to specialists. Hence, competition between professionals and fragmentation of care do occur, leading to poor quality of care and waste of resources. A strategy that improves communication and coordination between actors and stakeholders at a local scale represents a solution to develop integrative care oriented to people and community. The Local Health System (LHS), launched 15 years ago with some success in specific settings in Belgium, is the model used for this experience. What could be the opportunities and threats to improve coordination between levels of care in various local contexts? [less ▲]

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See detailLocal density approximation for the relativistic nucleons-nucleus potential,
Jaminon, Martine ULg

in Physical Review. C : Nuclear Physics (1982), 26

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See detailLocal dependence estimation using semi-parametric Archimedean copulas
Vandenhende, François; Lambert, Philippe ULg

in Canadian Journal of Statistics = Revue Canadienne de Statistique (2005), 33

The authors de¯ne a new semiparametric Archimedean copula family having a °exible depen- dence structure. The family's generator is a local interpolation of existing generators. It has locally-de¯ned ... [more ▼]

The authors de¯ne a new semiparametric Archimedean copula family having a °exible depen- dence structure. The family's generator is a local interpolation of existing generators. It has locally-de¯ned dependence parameters. The authors present a penalized constrained least-squares method to estimate and smooth these parameters. They illustrate the °exibility of their dependence model in a bivariate survival example. [less ▲]

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See detailLocal electron density reconstruction from simultaneous ground-based GNSS and ionosonde measurements
Stankov, Stanimir; Warnant, René ULg; Stegen, Koen

in Geophysical Research Abstracts (2009, April), 11(Abs. No EGU2009-10956),

Detailed reference viewed: 17 (1 ULg)
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See detailLocal ensemble assimilation scheme with global constraints and conservation
Barth, Alexander ULg; Yan, Yajing ULg; Canter, Martin ULg et al

Poster (2014, April)

Ensemble assimilation schemes applied in their original, global formulation have no problem in respecting linear conservation properties if the ensemble perturbations are setup accordingly. For realistic ... [more ▼]

Ensemble assimilation schemes applied in their original, global formulation have no problem in respecting linear conservation properties if the ensemble perturbations are setup accordingly. For realistic ocean systems, only a relatively small number of ensemble members can be calculated. A localization of the ensemble increment is thus necessary to filter out spurious long-range correlations. However, the conservation of the global property will be lost if the assimilation is performed locally since the conservation requires a coupling between model grid points, which is filtered out by the localization. In the ocean, the distribution of observations is highly inhomogeneous. Systematic errors of the observed parts of the ocean state can lead to spurious systematic adjustments of the non-observed part of the ocean state due to data assimilation. As a result, global properties which should be conserved, increase or decrease in long-term simulations. We propose an assimilation scheme (with stochastic or deterministic analysis steps) which is formulated globally (i.e. for the whole state vector) but where spurious long-range correlations can be filtered out. The scheme can thus be used to enforce global conservation properties and non-local observation operators. Both aspects are indeed linked since one can introduce the global conservation as a weak constraint by using a global observation operator. The conserved property becomes thus an observed value. The proposed scheme is tested with the Kuramoto-Sivashinsky model which is conservative. The benefit compared to the traditional covariance localization scheme (with an ad-hoc step enforcing conservation) where observations are assimilated sequentially is shown. The assimilation scheme is suitable to be implemented on parallel computers where the number of available computing cores is a multiple of the ensemble size. [less ▲]

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See detailLocal equating methods in the NEAT design
Janssen, Rianne; Magis, David ULg; San Martin, Ernesto et al

Conference (2009, April)

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See detailLocal estradiol synthesis in the brain and its implication in male and female sexual motivation of Japanese quail
de Bournonville, Catherine ULg; Schmit, Mélanie; Ball, Gregory F et al

in Trabajos del Instituto Cajal (2013)

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See detailLocal extinctions of Primates: demographic and genetic effectson vegetation
Culot, Laurence ULg; Galetti, Mauro

in Folia Primatologica : International Journal of Primatology = Internationale Zeitschrift für Primatologie = Journal international de Primatologie (2013), 84(262),

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See detailLocal food systems in Walloon Region (Belgium): definition and trends in supply and demand
Comps, Samuel ULg; Claustriaux, Jean-Jacques ULg; Vandercammen, Marc et al

Conference (2011, September 02)

Local food systems are one solution to promote local products in different ways and particularly by bringing together producers and consumers. This paper follows different purposes. The term “local food ... [more ▼]

Local food systems are one solution to promote local products in different ways and particularly by bringing together producers and consumers. This paper follows different purposes. The term “local food systems” will be defined as systems mobilizing not more than one intermediate person in a local area, where the exchanges must be monetized and where a relationship between the producer and the consumer is established. Then, a classification of the various initiatives of local food systems will be proposed. Thereafter the results of two studies conducted in the Walloon Region will be presented. The first study was conducted in Wallonia and Brussels in 2010 by the CRIOC to assess consumers’ perceptions and expectations of local products marketing using local food systems. The second one was conducted in 2010 to establish an inventory of local food systems in the Province of Namur. It had four main objectives: to describe categories of local food systems used, to give an overview of products supply, to understand main difficulties encountered by producers and to give benchmarks for the installation. The paper concludes that local food systems provide a wide diversity of selling networks which can be used. However, it is not easy for producers to meet consumers’ needs for local agricultural produce. The paper also puts emphasis on the necessity of including many fields of action to develop local food systems. [less ▲]

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See detailLocal goat in Kabylie (Chemini and Bouzeguene)
Moula, Nassim ULg; Michaux, Charles ULg; Philippe, François-Xavier ULg et al

Poster (2014, October 17)

The livestock sector plays a dynamic role in the economic development of rural areas in Algeria. Due to its adaptation to harsh environments, goat breeding is practiced in many areas of the country. To ... [more ▼]

The livestock sector plays a dynamic role in the economic development of rural areas in Algeria. Due to its adaptation to harsh environments, goat breeding is practiced in many areas of the country. To the north, it is confined to mountainous areas, but the bulk of the workforce is left in the steppe and semi-desert areas. The goat population in Algeria reached 3.8 million heads, ranking second after sheep. The present work contributes to a better characterisation of local goat in Kabylie for production and reproduction traits. The study was conducted in the regions of Chemini (Bejaia province) and Bouzeguene (Tizi-Ouzou province). A survey was conducted in 29 herds. The results revealed that the overall mean of goats per households was 6.69 ± 2.97. The purposes of keeping goat in Chemini and Bouzguene was private consumption of milk (82.76%) and meat (68.97%) as well as for commercial exchange (62.07%). The Kabyle goat is small (male: 62.23 cm and female: 58.41 cm) with long hair. Its ears are drooping, its convex profile has a slightly pronounced nasal split and its coat colour ranges from dark brown to black. However, the crossbreeding with exotic breeds (mainly with Saanen goat), controlled or uncontrolled, increased the frequency of white coat. The average age at puberty in males was 6.93 ± 1.04 and 7.38 ± 0.94 months in females. The reported age at first kidding and kidding interval were 13.03 ± 0.87 months and 7.83 ± 1.29 months, respectively. [less ▲]

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See detailLocal head-loss coefficient at the rectangular transition from a free-surface channel to a conduit
Van Nam, Nguyen; Archambeau, Pierre ULg; Dewals, Benjamin ULg et al

in Journal of Hydraulic Engineering (2013), 139(12), 1318-1323

Experimental tests have been performed to observe and determine, in stationary flow conditions, the local head loss at the transition from a free surface channel to a conduit. These investigations ... [more ▼]

Experimental tests have been performed to observe and determine, in stationary flow conditions, the local head loss at the transition from a free surface channel to a conduit. These investigations considered a wide range of discharge and varied dimensions and positions of a rectangular cross section conduit connected to the downstream extremity of a rectangular free surface channel. From the head loss evaluation results, simple analytical expressions to predict the local head loss coefficient value at the rectangular transition from a channel to a conduit are proposed and validated. [less ▲]

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See detailLocal Hydrological effects in Membach, Belgium: influence on the long term gravity variation
Van Camp, Michel; Dassargues, A.; Vanneste, K. et al

Conference (2003)

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See detailLocal Identification of Voltage Emergency Situations
Vournas, Costas; Van Cutsem, Thierry ULg

in IEEE Transactions on Power Systems (2008), 23(3), 1239-1248

This paper proposes a simple procedure to identify the onset of long-term voltage instability from the time evolution of the distribution voltages controlled by load tap changers. The moving average of ... [more ▼]

This paper proposes a simple procedure to identify the onset of long-term voltage instability from the time evolution of the distribution voltages controlled by load tap changers. The moving average of sampled measurements is computed and used to trigger local emergency signals. The method is validated on voltage signals obtained from time simulation of a realistic test system. The ability to identify instability in the critical area is demonstrated in three test cases. [less ▲]

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See detailLocal immune response in canine sino-nasal aspergillosis
Peeters, Dominique ULg

in Proceedings of the 16th Congress of the International Society for Human and Animal Mycology (2006, June)

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See detailA local influence approach applied to binary data from a psychiatric study.
Jansen, Ivy; Molenberghs, Geert; Aerts, Marc et al

in Biometrics (2003), 59(2), 410-9

Recently, a lot of concern has been raised about assumptions needed in order to fit statistical models to incomplete multivariate and longitudinal data. In response, research efforts are being devoted to ... [more ▼]

Recently, a lot of concern has been raised about assumptions needed in order to fit statistical models to incomplete multivariate and longitudinal data. In response, research efforts are being devoted to the development of tools that assess the sensitivity of such models to often strong but always, at least in part, unverifiable assumptions. Many efforts have been devoted to longitudinal data, primarily in the selection model context, although some researchers have expressed interest in the pattern-mixture setting as well. A promising tool, proposed by Verbeke et al. (2001, Biometrics 57, 43-50), is based on local influence (Cook, 1986, Journal of the Royal Statistical Society, Series B 48, 133-169). These authors considered the Diggle and Kenward (1994, Applied Statistics 43, 49-93) model, which is based on a selection model, integrating a linear mixed model for continuous outcomes with logistic regression for dropout. In this article, we show that a similar idea can be developed for multivariate and longitudinal binary data, subject to nonmonotone missingness. We focus on the model proposed by Baker, Rosenberger, and DerSimonian (1992, Statistics in Medicine 11, 643-657). The original model is first extended to allow for (possibly continuous) covariates, whereafter a local influence strategy is developed to support the model-building process. The model is able to deal with nonmonotone missingness but has some limitations as well, stemming from the conditional nature of the model parameters. Some analytical insight is provided into the behavior of the local influence graphs. [less ▲]

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See detailA Local Influence Approach to Sensitivity Analysis of Incomplete Longitudinal Ordinal Data
Van Steen, Kristel ULg; Molenberghs, G.; Verbeke, G. et al

in Statistical Modelling : An International Journal (2001), 1

Detailed reference viewed: 30 (12 ULg)