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See detailImpact model of spinal cord injury
Cantinieaux, Dorothée; Franzen, Rachelle ULg; Schoenen, Jean ULg

in Janowski, Miroslav (Ed.) Experimental Neurosurgery in Animal Models (2016)

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See detailImpact of 2D and 3D vision on performance of novice subjects using da Vinci robotic system
Blavier, Adelaïde ULg; Gaudissart, Quentin; Cadière, Guy-Bernard et al

in Acta Chirurgica Belgica (2006), 106(6), 662-664

Purpose of the study : The aim of this study was to evaluate the impact of 3D and 2D vision on performance of novice subjects using da Vinci robotic system. Methods : 224 nurses without any surgical ... [more ▼]

Purpose of the study : The aim of this study was to evaluate the impact of 3D and 2D vision on performance of novice subjects using da Vinci robotic system. Methods : 224 nurses without any surgical experience were divided into two groups and executed a motor task with the robotic system in 2D for one group and with the robotic system in 3D for the other group. Time to perform the task was recorded. Results : Our data showed significant better time performance in 3D view (24.67 +/- 11.2) than in 2D view (40.26 +/- 17.49, P < 0.001). Conclusions : Our findings emphasized the advantage of 3D vision over 2D view in performing surgical task, encouraging the development of efficient and less expensive 3D systems in order to improve the accuracy of surgical gesture, the resident training and the operating time. [less ▲]

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See detailImpact of 3000-t blast on unstable slopes near the Kambarata-2 HPP site, Kyrgyzstan
Torgoev, Isakbek; Havenith, Hans-Balder ULg; Strom, Alexander

in Margottini, CLaudio; Sassa, Kioji (Eds.) Landslide Science and Practice (2013)

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See detailImpact of 6 % hydroxyethyl starch (HES) 130/0.4 on the correlation between standard laboratory tests and thromboelastography (TEG(R)) after cardiopulmonary bypass.
HANS, Grégory ULg; Hartstein, Gary ULg; Roediger, Laurence et al

in Thrombosis research (2015), 135(5), 984-9

BACKGROUND: Hydroxyethyl starches (HES) affect the results of thromboelastography (TEG(R)). We sought to determine whether using HES rather than crystalloids for cardiopulmonary bypass (CPB) prime and ... [more ▼]

BACKGROUND: Hydroxyethyl starches (HES) affect the results of thromboelastography (TEG(R)). We sought to determine whether using HES rather than crystalloids for cardiopulmonary bypass (CPB) prime and intraoperative fluid therapy changes the TEG cutoff values best identifying patients with a low platelet count or a low fibrinogen level after CPB. METHODS: Data from 96 patients who had on-pump cardiac surgery, a TEG(R) (kaolin-heparinase) and standard investigations of blood clotting performed after separation from CPB and protamine administration were retrospectively reviewed. Patients were assigned to the HES or crystalloid group according to whether balanced 6% HES 130/0.4 or balanced crystalloids were used for intraoperative fluid therapy and pump prime. Mutlivariable linear regression models with computation of the standardized regression coefficients were used to identify independent associations between the four main TEG parameters (R time, alpha angle, K time and MA) and the type of fluid used, the INR, the aPTT, the fibrinogen level and the platelet count. Receiver-operating-characteristic curves were used to assess the effect of HES on the ability of TEG parameters to identify patients with a platelet count<80.000mul(-1) or a fibrinogen level<1.5 gr l(-1) and on the cutoff values best identifying these patients. RESULTS: The type of fluid used significantly affected the MA (P<0.001), the K time (P<0.001) and the alpha angle (P<0.001) regardless of the results of the standard clotting tests. According to standardized ss regression coefficients the platelet count and the type of fluid used were stronger predictors of the MA, the alpha angle and the K time than the fibrinogen level. MA better predicted platelets<80.000mul(-1) than K time and alpha angle (P=0.023). The best cutoff value of MA identifying patients with platelets<80.000mul(-1) was 62mm in the crystalloid group and 53mm in the HES group. MA, K time and alpha angle were poor predictors of the postoperative fibrinogen level. CONCLUSION: HES significantly changes the cutoff value of TEG(R) MA best identifying patients<80.000mul(-1) after on-pump cardiac surgery. [less ▲]

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See detailImpact of a camera change in ventriculography
Seret, Alain ULg; Blocklet, Didier; Lisart, Jean et al

in European Journal of Nuclear Medicine (2000), 27

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See detailImpact of a communication skills training program on residents' bad news disclosure in a simulated consultation : a randomized study
Damas, A.; Merckaert, I.; Libert, Y. et al

in Psycho-oncology (2009, June), 18 (Suppl. 2)

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See detailImpact of a formic/acetic acid treatment of beech wood on delignification and chemical structure of lignins
Simon, Mathilde ULg; Richel, Aurore ULg; Vanderghem, Caroline ULg et al

Conference (2011)

Lignocellulosic substrates constitute a promising alternative resource for the sustainable production of energy (biofuels), biobased products and organic compounds. In the past, the extraction and the ... [more ▼]

Lignocellulosic substrates constitute a promising alternative resource for the sustainable production of energy (biofuels), biobased products and organic compounds. In the past, the extraction and the valorization of cellulose (into fermentescible glucose) constituted the central axis of lignocellulosic biorefinery processes. Degraded hemicelluloses and lignins were however recovered as side-products with no possibilities of high-added value applications. Within the context of an integrated biorefinery, and for economic reasons, the recovery and the non-energetic transformation of lignins have opened recently new horizons. Lignin is a cross-linked phenolic polymer and is considered as a potential alternative to petrochemical polymers or as a source of antioxidants for cosmetics and food industry, resins, chelating agent... As the final application of lignin is dependent of both extraction process and type of lignocellulosic sources, the development of fast and efficient physicochemical characterization methods is thus a prerequisite to optimize extraction processing conditions. In this study, beech wood particles (Fagus sylvatica L.) collected in the region of Gaume (Belgium) were delignified at atmospheric pressure by a mixture of formic acid/acetic acid/water. The effect of cooking time and temperature was evaluated on delignification and on chemical structure of lignins obtained by precipitation from the black liquor after treatments. To study the delignification, a central composite design and response surface methodology were used for the optimization of two treatments parameters, i.e. time (between 1h30 and 4h30) and temperature (from 87 to 107°C). These two variables were optimized for delignification yield, pulp yield, concentration of degradation products (furfural and hydroxymethylfurfural) and for the amount of residual linkages between lignin constitutive units. On the basis of our results, higher delignification yields were obtained when cooking time and temperature increased. However, for high cooking times and temperatures, pulp yield decreased because hemicelluloses and cellulose were hydrolyzed and the production of furfural and hydroxymethylfurfural was augmented. The structural and physico-chemical features of extracted lignins were investigated with different analytical tools, namely infrared spectrometry, thermogravimetric analysis, size-exclusion chromatography, mono-dimensional nuclear magnetic resonance (NMR 1H and NMR 13C) and bidimensional NMR (heteronuclear HSQC experiments). The characterization of lignins indicated the occurrence of a repolymerization phenomenon when both cooking time and temperature increased. Indeed, HSQC NMR spectra presented oxidized syringyl units. Otherwise, thermogravimetric analysis and HSQC analysis showed the presence of hemicelluloses in lignin samples from soft treatments (1h30, 87°C). Some linkages between lignin and hemicelluloses were not cleaved under these experimental conditions. [less ▲]

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See detailImpact of a Greenland deglaciation on climate during the next millennia
Driesschaert, Emmanuelle; Brovkin, Victor; Fichefet, Thierry et al

Conference (2006, April 04)

A new Earth system model of intermediate complexity, LOVECLIM, has been developed in order to study long-term future climate changes. It includes an interactive Greenland and Antarctic ice sheet model ... [more ▼]

A new Earth system model of intermediate complexity, LOVECLIM, has been developed in order to study long-term future climate changes. It includes an interactive Greenland and Antarctic ice sheet model (AGISM) as well as an oceanic carbon cycle model (LOCH). Those climatic components can have a great impact on future climate. The few studies in recent literature assessing the impact of polar ice sheets on future climate draw very different conclusions, which shows the need for developing such a model. A set of numerical experiments have been performed in order to study the possible perturbations of climate induced by human activities over the next millennia. A particular attention is given to the Greenland ice sheet. In most of the projections, the Greenland ice sheet undergoes a continuous reduction in volume, leading to an almost total disappearance in the most pessimistic scenarios. The impact of the Greenland deglaciation on climate has therefore been assessed through a sensitivity experiment using the scenario SRES A2. The removal of the Greenland ice sheet is responsible for a regional amplification of the global warming inducing a total melt of Arctic sea ice in summer. The freshwater flux from Greenland generates large salinity anomalies in the North Atlantic Ocean that reduce the rate of North Atlantic Deep Water formation, slowing down slightly the oceanic thermohaline circulation. [less ▲]

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See detailIMPACT OF A HIGH LINEAR WEIGHT POLYMER CO-CONDITIONING WITH POLYALUMINIUM CHLORIDE ON DEWATERING AND CONVECTIVE DRYING OF URBAN RESIDUAL SLUDGE
Pambou, Yvon-Bert ULg; Fraikin, Laurent ULg; Salmon, Thierry ULg et al

Poster (2014, August)

This paper investigated the influence of Polyaluminium chloride (PAX) co-conditioning with a high linear weight polymer on the dewatering performance and the drying behavior of sludge. The CT linear ... [more ▼]

This paper investigated the influence of Polyaluminium chloride (PAX) co-conditioning with a high linear weight polymer on the dewatering performance and the drying behavior of sludge. The CT linear polymer with a high molecular weight was used combined with PAX for sludge flocculation prior to mechanical dewatering and drying. It was found that sludge conditioned with the couple PAX/ CT led to better flocculation/dewatering process regarding size flocs and specific resistance to filtration. Concerning drying, it appeared that this chemicals combination led to improved drying rates with effect of a reduction of the drying time, when compared to polyelectrolyte used without PAX adding. [less ▲]

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See detailThe impact of a minimum pension on old age poverty and its budgetary cost. Evidence from Latin Am
Pestieau, Pierre ULg; Dethier, Jean Jacques; Ali, Rabia

in Revista de Economıa del Rosario (2011), 14(2), 135-163

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See detailThe impact of a minimum pension on old age poverty and its budgetary cost. Evidence from Latin America
Pestieau, Pierre ULg; Dethier, Jean-Jacques; Rabia, Ali

in Revista de Economía del Rosario (2011), 14(2), 37-65

This paper examines the impact on old age poverty and the fiscal cost of universal minimum old age pensions in Latin America using recent household survey data for 18 countries. Alleviating old age ... [more ▼]

This paper examines the impact on old age poverty and the fiscal cost of universal minimum old age pensions in Latin America using recent household survey data for 18 countries. Alleviating old age poverty requires different approach from other age groups and a minimum pension is likely to be the only alternative available. First we measure old age poverty rates for all countries. Second we discuss the design of minimum pensions schemes, means-tested or not, as well as the disincentive effects that they are expected to have on the economic and social behavior of households including labor supply, saving and family solidarity. Third we use the household surveys to simulate the fiscal cost and the impact on poverty rates of alternative minimum pensionschemes in the 18 countries. We show that a universal minimum pension would substantially reduce poverty among the elderly except in Argentina, Brazil, Chile and Uruguay where minimum pension systems already exist and poverty rates are low. Such schemes have much to be commended in terms of incentives, spillover effects and administrative simplicity but have a high fiscal cost. The latter is a function of the age at which benefits are awarded, the prevailing longevity, the generosity of benefits, the efficacy ofmeans testing, and naturally the fiscal capacity of the country. [less ▲]

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See detailImpact of a mountain ultra-marathon on cardiac biomarkers
Le Goff, Caroline ULg; Gergelé, Laurent; Kaux, Jean-François ULg et al

in Crossing borders through sport science (2016, July)

Objectives. While moderate exercise has beneficial effects on the cardiovascular system, consequences of a supra-physiological effort are not clear yet. In particular, the physiological consequences of ... [more ▼]

Objectives. While moderate exercise has beneficial effects on the cardiovascular system, consequences of a supra-physiological effort are not clear yet. In particular, the physiological consequences of ultramarathons need to be further documented. The aim of the study was to assess the changes of various cardiac biomarkers after a mountain ultra-marathon. Material and methods. Blood and urine samples were collected on 28 runners (17 men) participating to the Ultra-Trail du Mont Blanc (105km, total positive elevation: 5600 m) at 3 different times: before the race (Pre), within 1 h after the finish (Post) and 7 days after the finish (D+7). Several biomarkers involved in heart disease (coronary syndrome, heart failure and fibrosis) and in inflammation were assayed on different analyzers such a COBAS® (for CKMB,TnThs, NT-proBNP, H-FABP and CRPs) and KRYPTOR® (for Copeptin). ST2 was measured manually with the Presage kit from CRITICAL DIAGNOSTIC®. Results. Plasma levels of cardiac markers (CKMB, TnThs, NT-proBNP, copeptin, H FABP, ST2) and inflammation (CRPs) increased significantly at Post. Means values increased from Pre to Post as follows: 2.3 to 91.9 UI/L for CKMB (p<0.0001); 7.6 to 31.7 ng/L for TnThs (p<0.0001); 41.7 to 1190.5 ng/L for NT-proBNP, 4.2 to 22.9 pmol/L for copeptin (p=0.001); 3.6 to 107.8 ng/mL for H-FABP (p<0.0001), 29.7 to 126.2 ng/mL for ST2 (p<0.0001); 0.5 to 29.1 mg/L for CRPs (p<0.0001). With the exception of a few (H-FABP, ST2, CRPs) biomarkers in some subjects, all values were back to Pre values at D+7. Discussion-conclusion. Prolonged strenuous running exercise caused an elevation in cardiac biomarkers. Elevation in CK-MB levels lacks specificity for cardiac damage as runners have increased CKMB from skeletal muscles as well. Previous studies suggested that exercise induced TnThs elevation is a benign reversible physiologic phenomenon but this parameter, as well as H-FABP, could be a sign of ischemia. Different phenomena occurred such as stretch of myocytes causing an increase in pressure or volume and neurohormonal activation which can explain the Copeptine and NT-proBNP increase, while ST2 is a biomarker of cardiac remodeling and fibrosis. CRP is an acute phase compound that tends to increase following a strenuous and prolonged bout of exercise and/or muscular injury. As the values tended to return within the normal reference range values within 7 days after the race, our study suggests that there is no permanent structural damage at the myocardium level. [less ▲]

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See detailImpact of a mutation in the mitochondrial LSU rRNA gene from Chlamydomonas reinhardtii on the activity and the assembly of respiratory-chain complexes
Remacle, Claire ULg; Gloire, Geoffrey ULg; Cardol, Pierre ULg et al

in Current Genetics (2004), 45(5), 323-330

Two substitutions A1090G and A1098C (together called the m mutation) located in the conserved GTPase domain of the mitochondrial LSU rRNA gene were recently shown to weakly compensate for the phenotypical ... [more ▼]

Two substitutions A1090G and A1098C (together called the m mutation) located in the conserved GTPase domain of the mitochondrial LSU rRNA gene were recently shown to weakly compensate for the phenotypical effect of a -1T frameshift mutation in the mitochondrial cox1 gene of C. reinhardtii. In order to analyze the impact of the m mutation on the mitochondrial translational machinery, a strain carrying the m mutation but wild-type for the cox1 gene was isolated. We found that the growth and the respiratory rate of the m mutant were affected and that the activities of complexes I, III, and IV, all containing mitochondria-encoded subunits, were lowered. In contrast the activities of complex II and of the alternative oxidase, both encoded exclusively by the nuclear genome, were not modified. The steady-state levels of complex I enzyme and of several components of the respiratory complexes I, III, and IV were also reduced in the mutant. We moreover showed that m did not suppress other frameshift or UGA stop mutations which affect mitochondrial genes. [less ▲]

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See detailImpact of a natural bluetongue serotype 8 infection on semen quality of Belgian rams in 2007
Kirschvink, N.; Raes, M.; Saegerman, Claude ULg

in Veterinary Journal (2007)

In 2006, bluetongue (BT) virus serotype 8 emerged in northern Europe and numerous ruminants were affected in the following year. Infertility in males is one of the consequences of BT, although its ... [more ▼]

In 2006, bluetongue (BT) virus serotype 8 emerged in northern Europe and numerous ruminants were affected in the following year. Infertility in males is one of the consequences of BT, although its severity and duration after natural infection has not been documented. In this report, the impact of BT-8 on clinical signs and semen quality of naturally infected rams is described through a longitudinal study of two Belgian ram populations (n=12 and n=24) and a cross sectional study in a further ram population (n=43). Macroscopic semen characteristics, semen concentration, motility, percentage of living and dead spermatozoa were assessed in 167 semen samples collected on 1-6 occasions from 79 BT-8 infected rams within 5-138 days after onset of clinical disease. These were compared with healthy control animals. Significant changes in all variables were observed after natural BT-8 infection. Total recovery occurred around 85 days after clinical disease in animals undergoing a close follow-up of semen quality. Good correspondence between the results of the longitudinal and cross sectional studies suggests that semen quality of BT-8 affected rams reached normal references values 63-138 days after clinical diagnosis of BT. In addition, semen concentration seems to be a sound epidemiological indicator of ram semen quality. [less ▲]

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See detailImpact of a natural bluetongue serotype 8 infection on semen quality of Belgian rams in 2007.
Kirschvink, Nathalie; Raes, Marianne; Saegerman, Claude ULg

in Veterinary Journal (2009), 182(2), 244-51

In 2006, bluetongue (BT) virus serotype 8 emerged in northern Europe and numerous ruminants were affected in the following year. Infertility in males is one of the consequences of BT, although its ... [more ▼]

In 2006, bluetongue (BT) virus serotype 8 emerged in northern Europe and numerous ruminants were affected in the following year. Infertility in males is one of the consequences of BT, although its severity and duration after natural infection has not been documented. In this report, the impact of BT-8 on clinical signs and semen quality of naturally infected rams is described through a longitudinal study of two Belgian ram populations (n=12 and n=24) and a cross sectional study in a further ram population (n=43). Macroscopic semen characteristics, semen concentration, motility, percentage of living and dead spermatozoa were assessed in 167 semen samples collected on 1-6 occasions from 79 BT-8 infected rams within 5-138 days after onset of clinical disease. These were compared with healthy control animals. Significant changes in all variables were observed after natural BT-8 infection. Total recovery occurred around 85 days after clinical disease in animals undergoing a close follow-up of semen quality. Good correspondence between the results of the longitudinal and cross sectional studies suggests that semen quality of BT-8 affected rams reached normal references values 63-138 days after clinical diagnosis of BT. In addition, semen concentration seems to be a sound epidemiological indicator of ram semen quality. [less ▲]

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See detailImpact of a one-day preventive voice program for teachers : A longitudinal study
Remacle, Angélique ULg; Gerber, Silvain; David, Claire et al

Conference (2015, September 02)

I. INTRODUCTION Teachers are professional voice users, i.e. people who rely on a consistent, special, or appealing voice quality to achieve their job. If afflicted with dysphonia or aphonia, they would ... [more ▼]

I. INTRODUCTION Teachers are professional voice users, i.e. people who rely on a consistent, special, or appealing voice quality to achieve their job. If afflicted with dysphonia or aphonia, they would generally loose motivation at work and seek alternative employment [1]. Teachers represent the largest group of professionals complaining of dysphonia: they represent 20% to 25% of the treatment-seeking workers [2, 3]. Voice disorders impact both physical and psychological health. They represent a public health problem, since they have considerable economic consequences in terms of treatment and replacement of professionals who suffer from these problems [4]. Moreover, they have been shown to interfere with quality of life, emotional state, job satisfaction, performance and attendance [4, 5]. Finally, a teacher’s dysphonia adversely impacts students’ comprehension and learning [6]. These negative effects of teachers’ voice disorders motivate to develop prevention programs and test their efficacy. This study aims to evaluate the impact over a five-month period of a one-day prevention program for female teachers. This program includes both direct and indirect methods. II. METHODS A. Participants Twenty-two female kindergarten and elementary schoolteachers with less than 5 years of experience participated in this study. Half of them (test group) took part in a one-day prevention program in October, while the other half (control group) received no counseling on the use of the voice. B. Assessments For each participant, five sustained /a/ vowels and the reading of a text were recorded (1) at two times of the workday (morning and evening), and (2) at three times of the year: October (T0), December (T1) and February (T2). For the sustained vowels, we measured maximum phonation time (MPT), mean fundamental frequency (F0), values of jitter, shimmer and harmonics-to-noise ratio (HNR). For the texts, we measured mean F0, standard deviation in F0 and intensity, and parameters related to speech rate (number of syllables per second, number of pauses and mean duration of pauses). For each parameter, a repeated-measures ANOVA (2 groups * 2 times of day * 3 times of year) was carried out. Participants also completed a questionnaire on voice use and comfort at the three test sessions. III. RESULTS A. Time of day effect The main effect of time of day showed an increase in the mean F0 of the vowels and the text following a workday (p<.01). MPT and HNR also increased (p<.01), while jitter and shimmer decreased at the end of the day (p<.05). The speech rate measures showed that the teachers tended to pause less often while reading the text at the end of the day, and their pauses were shorter (p<.05). B. Time of year effect The main effect of time of year showed an increase in the mean F0 of the vowels and the text during the year (p<.01), with the highest values observed in December (T1). The speech rate measures also showed an increase in the number of syllables per second (p<.01) and a tendency for speakers to pause less often later in the year. C. Group effect Several acoustic parameters showed that voice changed during the day and during the year in significantly different ways in the two groups. Thus, the MPT increased more during the year for the control group than for the test group. The elevation of mean F0 during the day increased to a similar degree for both groups between T0 and T1, but continued to increase until T2 for the control group, while it decreased for the test group. Jitter and shimmer decreased significantly following a workday for both groups at T0, and this decrease was more marked for the test group at T1 and T2. Finally, analysis of the questionnaires showed a very strong deterioration in teachers’ self-evaluations of vocal comfort and control at T1; nevertheless there were significantly fewer complaints from the group that received the prevention program. IV. DISCUSSION AND CONCLUSION For both groups, the changes in the observed parameters suggested an increase in vocal fatigue and hyperfunctional phonation during the day and during the year. The results showed greater vocal deterioration in December than at the other points in the school year (October and February). For several acoustic parameters, the comparison of the two groups showed a less severe vocal deterioration for subjects who received the preventive program. Moreover, the questionnaires showed that the prevention program had a significantly positive impact on the changes in the teachers’ perception during the year. These results encourage to offer such preventive interventions to teachers before or during their career, since they have a positive impact on teachers’ perception and vocal comfort. V. REFERENCES [1] Titze IR, Lemke J, Montequin D. (1997). Populations in the U.S. workforce who rely on voice as a primary tool of trade: A preliminary report. Journal of Voice, 11(3), 254-259. [2] Van Houtte, E., Van Lierde, K., D'Haeseleer, E., & Claeys, S. (2010). The prevalence of laryngeal pathology in a treatment-seeking population with dysphonia. Laryngoscope, 120(2), 306-312. [3] Remacle, A., Petitfils, C., Lejeune, L., Finck, C., & Morsomme, D. (2014). Quel est le profil professionnel des patients consultant en phoniatrie ? 70e Congrès de la Société Française de Phoniatrie, Paris, France. (October 13, 2014). [4] Roy, N., Merrill, R. M., Thibeault, S., Parsa, R. A., Gray, S. D., & Smith, E. M. (2004). Prevalence of voice disorders in teachers and the general population. Journal of Speech, Language, and Hearing Research, 47(2), 281-293. [5] Chen, S. H., Chiang, S.-C., Chung, Y.-M., Hsiao, L.-C., & Hsiao, T.-Y. (2010). Risk factors and effects of voice problems for teachers. Journal of Voice, 24(2), 183-190. [6] Morsomme, D., Minel, L., & Verduyckt, I. (2011). Impact of teachers’ voice quality on children’s language processing skills. Vocologie: Stem en Stemstoornissen, 4, 9-15. [less ▲]

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