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See detailPET scan imaging in oncology.
Jerusalem, Guy ULg; Hustinx, Roland ULg; Beguin, Yves ULg et al

in European Journal of Cancer (2003), 39(11), 1525-34

With the emergence of positron emission tomography (PET) from research laboratories into routine clinical use, it is important to redefine the most appropriate use of each imaging technique. The aim of ... [more ▼]

With the emergence of positron emission tomography (PET) from research laboratories into routine clinical use, it is important to redefine the most appropriate use of each imaging technique. The aim of this review article is to show the potential of PET in oncology. We discuss the most promising indications and the perspectives for the future. We will also point out the shortcomings and the important questions to be answered before fully considering PET as a necessary tool in the day-to-day practice of oncology. Although many studies have documented the high accuracy of 18F-FDG PET for the detection and staging of malignant tumours and for the monitoring of therapy results in these patients, it is very important to assess the impact of the technique on patient outcome and to show cost-effectiveness from the societal viewpoint. [less ▲]

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See detailPET scanning and neuronal loss in acute vegetative state
Laureys, Steven ULg; Faymonville, Marie ULg; Moonen, Gustave ULg et al

in Lancet (2000), 355(9217), 1825-1826

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See detailPET-CT and PET-MRI in Oncology, A practical Guide: Gastrointestinal (135-159)
HUSTINX, Roland ULg

in PELLER, PATRICK; SUBRAMANIAM, RATHAN; GUERMAZI, ALI (Eds.) MEDICAL RADIOLOGY - DIAGNOSIS IMAGING : PET-CT and PET-MRI in Oncology - A pratical Guide (2012)

PET-CT combines in a single imaging session both anatomical and metabolic information. Depending on the strategy, the CT part of the study may yield only crude anatomical information and attenuation ... [more ▼]

PET-CT combines in a single imaging session both anatomical and metabolic information. Depending on the strategy, the CT part of the study may yield only crude anatomical information and attenuation correction for the PET part, or it may offer full radiological diagnostic features. Regarding the radiotracers for gastrointectinal oncology, FDG remains the mainstay but alternative compounds aimed at more specific biological targets are actively tested. In particular Ga-68-labelled DOTA derivatives image somatostatine receptors with exquisite sensitivity and specificity. In clinical practice, several indications are well recognized for FDG PET-CT. These include the initial staging of esophageal, pancreatic and rectal cancers with a clinical impact in a significal proportion of patients. The metabolic activity, as recorded prior to any treatment, holds prognostic information in esophageal and rectal cancers, as well as GISTs. Methodological issues remain to be solved, but the potential is clearly present so that an increased clinical role is highly likely in the near future. FDG PET-CT is a major clinical tool in the detection and staging of recurrent colorectal cancer, and for determining the resectability of liver metastases. Ongoing developments include technological advances, in particular the combined PET-MR devices, and alternative tracers, such as those imaging angiogenesis. [less ▲]

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See detailPET/CT in gastrointestinal tumors : fast technological changes lead to improved patient management
Hustinx, Roland ULg

in PET Clinics (2008), 3

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See detailPET/CT in head and neck cancer: an update.
Hustinx, Roland ULg; Lucignani, Giovanni

in European Journal of Nuclear Medicine and Molecular Imaging (2010), 37(3), 645-51

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See detailPET/CT of skull base meningiomas using 2-F-18-fluoro-L-tyrosine: Initial report
Rutten, Isabelle; Cabay, Jean-Evrard ULg; Withofs, Nadia ULg et al

in Journal of Nuclear Medicine (2007), 48(5), 720-725

Precise delineation of the shape of skull base meningiomas is critical for their treatment and follow-up but is often difficult using conventional imaging such as CT and MRI. We report our results with ... [more ▼]

Precise delineation of the shape of skull base meningiomas is critical for their treatment and follow-up but is often difficult using conventional imaging such as CT and MRI. We report our results with PET/CT and 2-(18)F-fluoro-L-tyrosine ((18)F-TYR), a marker of amino acid transport, as part of the yearly follow-up of irradiated patients. METHODS: Eleven patients (mean age, 56.5 y) with skull base meningiomas (n=13 lesions) previously irradiated were included. All patients received 300 MBq of (18)F-TYR and were imaged after 30 min of uptake, using a dedicated PET/CT system. The images were first visually examined, and regions of interest (ROI) were then placed over the transaxial PET slice showing the highest uptake. Another ROI was placed over the normal parietal cortex. Tumor-to-cortex activity ratios were obtained by dividing the maximum pixel value in the tumor ROI by the maximum pixel value in the cortex ROI. The PET/CT images were compared with the MR images obtained as part of routine follow-up. RESULTS: Accumulation of the tracer was higher in all meningiomas than in the surrounding tissue. The tumor-to-cortex activity ratio was 2.53 +/- 0.35 (range, 1.3-6). Nonneoplastic tissue such as hyperemic cavernous sinus did not take up the radionuclide and was therefore easily distinguished from the meningioma. The (18)F-TYR anomalies completely overlapped with the MR image in 54% of the tumors, extended beyond the MRI lesion in 38% of the tumors, and were smaller in 8% of the tumors. CONCLUSION: Meningiomas of the skull base are clearly visualized using (18)F-TYR PET/CT, even after irradiation. In addition to MRI, (18)F-TYR PET/CT images may contribute to the evaluation, delineation, and follow-up of these tumors. [less ▲]

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See detailPetae, petitiones, i gladiatori. Una nota su Serv. Verg. Aen. 9, 439 ed il PRyl. III 477
Scappaticcio, Maria Chiara ULg

in MD. Materiali e Discussioni per l'Analisi dei Testi Classici (in press)

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See detailPeter Johnson, "Pretty Happy !
Delville, Michel ULg

in Literary Review (2001)

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See detailPeter Johnson, Love Poems for the Millenium
Delville, Michel ULg

in Literary Review (2001)

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See detailPeter Kuper: The Bridge
Meesters, Gert ULg

in Deus ex machina (2008), 32(125), 49

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See detailPeter Ladislaw Hammer (1936-2006)
Boros, Endre; Crama, Yves ULg; Simeone, Bruno

in 4OR : Quarterly Journal of the Belgian, French and Italian Operations Research Societies (2007), 5(1), 1-4

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See detailPeter Verhelst. Entre corps et rêve
Steyaert, Kris ULg

Article for general public (2010)

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See detailLe petit atlas géopolitique
Merenne-Schoumaker, Bernadette ULg

Cartographic material (1990)

Introduction to a geopolitical facts reading via 21 different situations

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See detailLe Petit bottin des lettres et des arts. Discours et effets d'une topographie fin de siècle
Saint-Amand, Denis ULg

Conference (2011, January 14)

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See detailLe petit cinéma de Georges Simenon
Tomasovic, Dick ULg

in Bajomée, Danielle (Ed.) Simenon, une légende du XXe siècle (2003)

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See detailPetit mais costaud: une nouvelle façon de voir les planètes
Nazé, Yaël ULg

Article for general public (2010)

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See detailLe petit monde des grandes entreprises belges : conseils d'administration, consanguinité et collectivisme pratique
Geuens, Geoffrey ULg

Conference (2011, January 13)

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See detailPetit rappel concernant le cacul de la prescription de l'action publique en matière de moeurs
Monville, Pierre ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2003)

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See detail- Petit tour du monde du contradictoire dans le procès pénal
Jacobs, Ann ULg

in Ribeyre, Cédric (Ed.) Le contradictoire dans le procès pénal : nouvelles perspectives (2012)

Présentation du caractère contradictoire de la procédure pénale au cours de ses différentes phases en droit comparé.

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See detailPetit, mais costaud !
Grandfils, Christian ULg

in FNRS NEWS (2011)