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See detailIndividual variation of gait parameters along a 500 meter walk in people with multiple sclerosis and healthy volonteers
Phan-Ba, Rémy; Giet, Amaury; Pierard, Sébastien ULg et al

Poster (2015, April 10)

Background: we previously demonstrated the usefulness of the Deceleration Index (DI, the ratio between the last 100m of the Timed 500-Meter Walk test –T500MW – and the walking speed - WS – of the Timed 25 ... [more ▼]

Background: we previously demonstrated the usefulness of the Deceleration Index (DI, the ratio between the last 100m of the Timed 500-Meter Walk test –T500MW – and the walking speed - WS – of the Timed 25-Foot Walk Test with a propelled start – T25FW+) to evaluate motor fatigue over a long walking distance in people with multiple sclerosis (pwMS). We also recently designed and internally validated a new gait analysis tool for pwMS (GAIMS) that can measure other relevant gait characteristics than the sole WS, such as ataxia, asymmetry and perhaps spasticity. Aims: (i) To compare various gait characteristics between the last and the first 100m of the T500MW in a population of pwMS and healthy volunteers (HV), (ii) to compare the ratio between the last and the first 100m of the T500MW with the DI, and (iii) their relationship with the EDSS. Methods : Subjects were asked to perform the T25FW+ and the T500MW as part of a multimodal evaluation at the MS Clinic of the CHU of Liège. Their gait characteristics were measured using GAIMS. (i) Paired Student’s t-tests were performed on various gait characteristics extracted during the last and first 100m of the T500MW with .05 as a level of significance, (ii) Spearman correlation coefficient (ρ) was calculated (ii) between these ratio and (iii) subject’s EDSS. Results: Seventy-one pwMS and 129 were enrolled in our study. (i) Significant differences were observed for speed related gait characteristics between the last and first 100m of the T500MW, but also for gait characteristics related to ataxia and precision of foot placement. (ii) A moderate positive correlation was observed between the WS ratio of the last and first 100m of the T500MW and the DI. (iii) The correlation between the DI and the EDSS was weakly negative, while the one between the last and first 100m of the T500MW ratio and the EDSS was moderatly negative. Conclusion: (i) As previously demonstrated, we here confirm that alongside to WS, there are other gait features affected by locomotor fatigue over a long walking distance, (ii) the moderate positive correlation between the DI and the last/first 100m of the T500MW indicates that these measures are not the same and that next to a long distance walking test such as the T500MW, a short one such as the T25FW+ remains useful. (iii) The last/first 100m of the T500MW is better correlated to the EDSS and might be a better predictive tool of pwMS’ neurologic state than the DI. [less ▲]

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See detailIndividual – to – resource landscape interaction strength can explain different collective feeding behaviours
Bode, Nikolai WF; Delcourt, Johann ULg

in PLoS ONE (2013), 8(10), 75879

Taking in sufficient quantities of nutrients is vital for all living beings and in doing so, individuals interact with the local resource environment. Here, we focus explicitly on the interactions between ... [more ▼]

Taking in sufficient quantities of nutrients is vital for all living beings and in doing so, individuals interact with the local resource environment. Here, we focus explicitly on the interactions between feeding individuals and the resource landscape. In particular, we are interested in the emergent movement dynamics resulting from these interactions. We present an individual-based simulation model for the movement of populations in a resource landscape that allows us to vary the strength of the interactions mentioned above. The key assumption and novelty of our model is that individuals can cause the release of additional nutrients, as well as consuming them. Our model produces clear predictions. For example, we expect more tortuous individual movement paths and higher levels of aggregation in populations occupying homogeneous environments where individual movement makes more nutrients available. We also show how observed movement dynamics could change when local nutrient sources are depleted or when the population density increases. Our predictions are testable and qualitatively reproduce the different feeding behaviours observed in filter-feeding ducks, for example. We suggest that considering two-way interactions between feeding individuals and resource landscapes could help to explain fine-scale movement dynamics. [less ▲]

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See detailIndividualisation de l'activité des élèves. Comparaison des propositions formulées lors de la présentation des tâches
Cloes, Marc ULg; Pirottin, Véronique; Ledent, Maryse et al

in Gréhaigne, J. F.; Mahut, N.; Marchal, D. (Eds.) Qu'apprennent les élèves en faisant des activités physiques et sportives?/What do people learn from physical activity program? Actes sur CD Rom du Congrès International de l'AIESEP (1999)

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See detailL'individualisation de l'enseignement dans une école multilatérale
de Landsheere, Gilbert ULg

in Education : tribune libre d'information et de discussion pédagogiques (1961), (69), 109-124

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See detailL'individualisation des traitements en institution d'éducation
Born, Michel ULg

in Bulletin de Liaison de l'Office de la Protection de la Jeunesse (1975), 1

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See detailIndividualiser la détention? L’accompagnement face à la gestion des risques
Dubois, Christophe ULg

Conference (2011, September 13)

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See detailIndividualisme, autonomie et dépendance dans la société contemporaine
Jacquemain, Marc ULg

Scientific conference (2003, March)

Du point de vue de la logique sociologique des conséquences inattendues, le papier tente de montrer que la véritable autonomie, comme le dit bien Richard Sennett, n'est de ne pas dépendre de personne (ce ... [more ▼]

Du point de vue de la logique sociologique des conséquences inattendues, le papier tente de montrer que la véritable autonomie, comme le dit bien Richard Sennett, n'est de ne pas dépendre de personne (ce qui définit la solitude ou l'exclusion), mais qu'elle se construit dans l'interdépendance mutuelle. L'article reprend et développe un des arguments esquissés dans "La Raison névrotique" [less ▲]

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See detailIndividualismo y sociedad
Jacquemain, Marc ULg

Scientific conference (2002, December)

Segun las mismas lienas que la critica de la escuela de Frankfurt, la conferencia expone como los nuevos "postmaterialisas" (Inglehart) son a la vez mas dispuestos a la democracia y la tolerancia pero al ... [more ▼]

Segun las mismas lienas que la critica de la escuela de Frankfurt, la conferencia expone como los nuevos "postmaterialisas" (Inglehart) son a la vez mas dispuestos a la democracia y la tolerancia pero al mismo tiempo, menos dispuestos a la solidaridad, lo que fragiliza precisamente la base misma del postmaterialismo [less ▲]

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See detailAn individualized and everyday life approach to cognitive rehabilitation in schizophrenia: A case illustration
Levaux, Marie-Noëlle ULg; Fonteneau, Benjamin; Laroi, Frank ULg et al

in Rehabilitation Research and Practice (2012)

Objective. The effectiveness of an individualized and everyday approach to cognitive rehabilitation for schizophrenia was examined in a case study. Method. After cognitive and functional assessment ... [more ▼]

Objective. The effectiveness of an individualized and everyday approach to cognitive rehabilitation for schizophrenia was examined in a case study. Method. After cognitive and functional assessment, concrete objectives were targeted for the person’s everyday complaints. Strategies were constructed based on an analysis of the cognitive profile, daily life functioning, and processes involved in activities. They included a memory strategy for reading, a diary to compensate memory difficulties, and working memory exercises to improve immediate processing of information when reading and following conversations. Efficacy was assessed with outcome measures. Results. The program had beneficial effects on the person’s cognitive and everyday functioning, which persisted at a 3-year follow-up. Conclusion. Findings provide suggestive evidence that an individualized and everyday approach may be a useful alternative in order to obtain ameaningfully lasting transfer of training to daily life, compared to the nomothetic ones which dominate the field. [less ▲]

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See detailIndividualized Nutrition of preterm: What are the challenges?
SENTERRE, Thibault ULg

in SENTERRE, Thibault (Ed.) Symposium on Intrauterine and Early Postnatal Nutrition: Long-Term Outcome (2015)

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See detailIndividualized versus standardized exercise training for claudicant patients.
Magne, Julien ULg; Boccalon, H; Bouley, M et al

Conference (2003)

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See detailIndividualizing treatment of type 2 diabetes by targeting postprandial or fasting hyperglycaemia: Response to a basal vs a premixed insulin regimen by HbA quartiles and ethnicity.
Scheen, André ULg; Schmitt, H.; Jiang, H. H. et al

in Diabetes & metabolism (2015), 41(3), 216-222

AIM: This study evaluated the proportions of prandial (PHG) vs fasting hyperglycaemia (FHG) over 24h in a group of patients with type 2 diabetes (overall and for Caucasian vs Asian patients), and tested ... [more ▼]

AIM: This study evaluated the proportions of prandial (PHG) vs fasting hyperglycaemia (FHG) over 24h in a group of patients with type 2 diabetes (overall and for Caucasian vs Asian patients), and tested the hypothesis that an insulin regimen with a prandial component allows a greater response than basal insulin at low glycated haemoglobin (HbA1c) levels with a higher proportion of PHG than FHG. METHODS: Relative contributions of PHG and FHG to overall hyperglycaemia were analyzed by baseline HbA1c quartiles and by ethnicity at baseline and after 24-week treatment with either insulin glargine or insulin lispro mix 25 in the DURABLE study. RESULTS: With increasing baseline HbA1c, the mean relative contribution of PHG to the total area under the curve decreased (from 41% to 27%) while FHG was increased (from 59% to 73%). Both insulins decreased FHG, but only insulin lispro mix 25 decreased PHG. More patients with baseline HbA1c<9%, where PHG was more relevant, achieved the target HbA1c of<7% at endpoint with insulin lispro mix 25 compared with glargine. On average, Asians had a 10% larger contribution of PHG at all HbA1c quartiles, and a lower proportion of Asians reached the HbA1c target of<7% with either insulin treatment compared with Caucasians. CONCLUSION: At baseline, the contribution of FHG to overall hyperglycaemia predominated at all HbA1c quartiles, whereas PHG was more clinically relevant at lower HbA1c levels and with a greater response to insulin lispro mix 25. Asians had a greater proportion of PHG and a lesser response to either insulins compared with Caucasians. Thus, responses to diabetes drugs by baseline HbA1c and ethnicity are worth investigating to better target and individualize treatment. [less ▲]

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See detailIndividuele rechtsbescherming, Europese netwerken van nationale toezichthouders en Lamfalussy-Convergentie
Van Cleynenbreugel, Pieter ULg

in S.E.W. - Tijdschrift voor Europees en Economisch Recht (2010)

This article analyses how the EU principle of effective judicial protection is protected and enabled in the context of EU informal networks of national supervisors. Those networks, by virtue of having no ... [more ▼]

This article analyses how the EU principle of effective judicial protection is protected and enabled in the context of EU informal networks of national supervisors. Those networks, by virtue of having no recognised EU law existence, require a combination of EU law principles and national procedural rules in order for their decisions to be held to account in court. The article analyses this situation and offers a framework for reflection on how to approach this problem. [less ▲]

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See detailL'indivision
Leleu, Yves-Henri ULg

in Brat, S.; Leleu, Yves-Henri; Van Gysel, A.-Ch. (Eds.) et al Union libre. Commentaire pratique (2005)

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See detailIndo-iranien *aruna
Swennen, Philippe ULg

in Journal Asiatique (2003), 291

In sanskrit, aruna- means "red, pink". In Avestan, occidental scholars translate auruna by "wild". Nothing explains this paradox between two words whose etymological equivalence is obvious. A precise ... [more ▼]

In sanskrit, aruna- means "red, pink". In Avestan, occidental scholars translate auruna by "wild". Nothing explains this paradox between two words whose etymological equivalence is obvious. A precise reading of the Rig-Vedic stanzas shows that the feminine form of this adjective always qualifies the Dawn. This systematic use modified the meaning of the adjective. Beyond its chromatic value, it indicates in the Rigvedic poetries the intermediate time linking day and night. [less ▲]

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See detailIndo-iranien *nivaidaia: le mécanisme de l'annonce liturgique
Swennen, Philippe ULg

in Estudios Iranios y Turanios (2015), 2

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See detailIndo-Trinidadian Women and the Indian Public Sphere: Women under the Influence?
Munos, Delphine ULg

Conference (2016, January 06)

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See detailIndol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.
Dolusic, Eduard; Larrieu, Pierre; Blanc, Sébastien et al

in Bioorganic & Medicinal Chemistry (2011), 19(4), 1550-61

Indoleamine 2,3-dioxygenase (IDO) is a heme dioxygenase which has been shown to be involved in the pathological immune escape of diseases such as cancer. The synthesis and structure-activity relationships ... [more ▼]

Indoleamine 2,3-dioxygenase (IDO) is a heme dioxygenase which has been shown to be involved in the pathological immune escape of diseases such as cancer. The synthesis and structure-activity relationships (SAR) of a novel series of IDO inhibitors based on the indol-2-yl ethanone scaffold is described. In vitro and in vivo biological activities have been evaluated, leading to compounds with IC(50) values in the micromolar range in both tests. Introduction of small substituents in the 5- and 6-positions of the indole ring, indole N-methylation and variations of the aromatic side chain are all well tolerated. An iron coordinating group on the linker is a prerequisite for biological activity, thus corroborating the virtual screening results. [less ▲]

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