Perspective in the treatment of insulin resistance.
in Human Reproduction (1997), 12 Suppl 1
Improving the action of insulin is a relatively new concept in therapy. It should, however, become more and more important because of the rapid expansion of the insulin resistance syndrome (including ... [more ▼]
Improving the action of insulin is a relatively new concept in therapy. It should, however, become more and more important because of the rapid expansion of the insulin resistance syndrome (including upper body adiposity, glucose intolerance, hypertension, dyslipidaemia, etc.) in industrialized countries and its dramatic consequences for public health. Insulin sensitivity can be improved by non-pharmacological means, essentially reduction of excessive body weight, promotion of regular physical activity and modification of dietary habits, as well as, possibly, cessation of smoking and correction of subclinical magnesium deficiency. Currently available pharmacological means mainly include the biguanide compound metformin and possibly anti-obesity agents, such as (d-) fenfluramine, fluoxetine and benfluorex. New compounds aiming at improving the action of insulin are in development, especially the thiazolidinedione derivatives (e.g. troglitazone), known as 'insulin sensitizers'. Treatment of insulin resistance may have important gynaecological applications, essentially in polycystic ovary syndrome and, possibly, after menopause. Hopefully, improving insulin sensitivity could ameliorate the cardiovascular prognosis of numerous individuals having some or all components of insulin resistance syndrome. [less ▲]Detailed reference viewed: 5 (1 ULg)
Perspective in three-dimensional modelling of the marine system
Nihoul, Jacques ; Djenidi, Salim
in Nihoul, J. C. J.; Jamart, B. M. (Eds.) Three-dimensional Models of Marine and Estuarine Dynamics (1987)Detailed reference viewed: 7 (0 ULg)
"La perspective interculturelle dans l'enseignement d'une langue étrangère: le cas du français au Maroc" (cycle de conf.)
Scientific conference (2008, March)Detailed reference viewed: 10 (1 ULg)
A perspective on cold enzymes: Current knowledge and frequently asked questions
; Blaise, Vinciane ; et al
in Cellular and Molecular Biology (2004), 50(5), 643-655
Studies on psychrophilic enzymes to determine the structural features important for cold-activity have attracted increased attention in the last few years. This enhanced interest is due to the attractive ... [more ▼]
Studies on psychrophilic enzymes to determine the structural features important for cold-activity have attracted increased attention in the last few years. This enhanced interest is due to the attractive properties of such proteins, i.e. a high specific activity and a low thermal stability, and thus, these enzymes constitute a tremendous potential for fundamental research and biotechnological applications. This review examines the impact of low temperatures on life, the diversity of adaptation to counteract these effects and gives an overview of the features proposed to account for low thermal stability and cold-activity, following the chronological order of the catalytic cycle phases. Moreover, we present an overview of recent techniques used in the analysis of the flexibility of a protein structure which is an important concept in cold-adaptation; an overview of biotechnological potential of psychrophilic enzymes and finally, a few frequently asked questions about cold-adaptation and their possible answers. [less ▲]Detailed reference viewed: 32 (2 ULg)
Perspective taking to assess self-personality: What's modified in Alzheimer's disease?
; Collette, Fabienne ; D'Argembeau, Arnaud et al
in Neurobiology of Aging (2009), 30(10), 1637-1651
Personality changes are frequently described by caregivers of patients with Alzheimer's disease, while they are less often reported by the patients. This relative anosognosia of Alzheimer disease (AD ... [more ▼]
Personality changes are frequently described by caregivers of patients with Alzheimer's disease, while they are less often reported by the patients. This relative anosognosia of Alzheimer disease (AD) patients for personality changes might be related to impaired self-judgment and to decreased ability to understand their caregiver's perspective. To investigate this issue, we explored the cerebral correlates of self-assessment and perspective taking in patients with mild AD, elderly and young volunteers. All subjects assessed relevance of personality traits adjectives for self and a relative, taking either their own or their relative's perspective, during a functional imaging experiment. The comparison of subject's and relative's answers provided congruency scores used to assess self-judgment and perspective taking performance. The self-judgment "accuracy" score was diminished in AD, and when patients assessed adjectives for self-relevance, they predominantly activated bilateral intraparietal sulci (IPS). Previous studies associated IPS activation with familiarity judgment, which AD patients would use more than recollection when retrieving information to assess self-personality. When taking a third-person perspective, patients activated prefrontal regions (similarly to young volunteers), while elderly controls recruited visual associative areas (also activated by young volunteers). This suggests that mild AD patients relied more on reasoning processes than on visual imagery of autobiographical memories to take their relative's perspective. This strategy may help AD patients to cope with episodic memory impairment even if it does not prevent them from making some mind-reading errors. [less ▲]Detailed reference viewed: 57 (7 ULg)
La perspective, entre projet plastique et projection intellectuelle
in SIC! (2009), 4
De nature à la fois technique et philosophique, le problème de la perspective importe ici pour deux raisons au moins. D’abord en tant qu’il est lié à la pratique du dessin: l’effet de la perspective ... [more ▼]
De nature à la fois technique et philosophique, le problème de la perspective importe ici pour deux raisons au moins. D’abord en tant qu’il est lié à la pratique du dessin: l’effet de la perspective repose sur un jeu de lignes participant à la construction de la représentation — lignes vouées, en général, à disparaître sous la couche picturale. Ensuite, le problème de la perspective apparaît comme une variation du thème — désormais fameux — de la double signification du disegno (dessin/dessein) mise en évidence par Robert Klein dans la forme et l’intelligible, critiquée par Georges Didi-Huberman dans "Devant l’image". En effet, le terme «perspective» semble relever d’une même ambivalence sémantique. Il désigne tout à la fois une technique de représentation picturale et une opération intellectuelle (celle qui consiste, pour le dire d’abord platement, à prendre de la distance, à «mettre les choses en perspective»). Il y aurait donc deux axes au «paradigme perspectif»: l’un pictural et processuel, l’autre cognitif. Ces deux axes seront ici décrits dans leur croisement. [less ▲]Detailed reference viewed: 50 (12 ULg)
Perspectives - Quel avenir pour les cuvettes oasiennes dans le Niger oriental ?
Tychon, Bernard ; ; Ozer, André et al
in Geo-Eco-Trop (2009), 33
The oasian interdunal depressions of eastern Niger are areas of life providing refuge to agro-pastoral activities in a generally hostile environment. The inter-university Targeted Program (ITP) funded by ... [more ▼]
The oasian interdunal depressions of eastern Niger are areas of life providing refuge to agro-pastoral activities in a generally hostile environment. The inter-university Targeted Program (ITP) funded by the Coopération Universitaire au Développement (CUD) called "Invasion of circular lowlands (cuvettes) of south-eastern Niger by aeolian deposits: processes, impacts and means of struggle" has studied the problem of silting of these refuge areas and proposed technical means, including physical and biological fixation of dunes that threaten the villages and interdunal depressions. Given the increasing human pressure and the present climate context that seems to move towards dryer conditions, environmental degradation of the study area should be investigated more broadly. Set up of strategies to allow people to adapt their conditions of life to an environment increasingly rough should also be considered. This paper presents some possible options for adaptation and examines the question of the very future of these interdunal depressions. [less ▲]Detailed reference viewed: 51 (9 ULg)
Perspectives : Compromis tragiques ou défense stérile des identités politiques
in Fournier, Bernard; Reuchamps, Min (Eds.) Le fédéralisme en Belgique et au Canada (2009)Detailed reference viewed: 19 (8 ULg)
Perspectives à l'horizon 1992 de la mobilité des biens et des personnes dans la CEE. Conclusions du congrès "Transports à l'Horizon 1992" GTU-AIL
in Bulletin de l'AILG (1990), (12), 3Detailed reference viewed: 6 (2 ULg)
Perspectives concernant les voies d'administration inhabituelles de l'insuline. Les voies orale, rectale et nasale.
Scheen, André ; Paquot, Nicolas ; Lefebvre, Pierre
in Annales d'Endocrinologie (1988), 49(4-5), 386-90
The present review concerns the current possibilities of insulin administration through the oral, rectal or nasal routes. The use of vehicle such as liposomes or various polymers protecting the hormone ... [more ▼]
The present review concerns the current possibilities of insulin administration through the oral, rectal or nasal routes. The use of vehicle such as liposomes or various polymers protecting the hormone against the digestive enzymes allowed to improve the absorption of insulin after its oral administration. Moreover, the use of various surfactants favours the resorption of insulin through the intestinal, rectal and nasal mucosae. However until now, none of these routes has sufficient reliability and reproducibility to be considered for routine treatment of diabetes mellitus. [less ▲]Detailed reference viewed: 44 (1 ULg)
Perspectives d'avenir du traitement anti-arthrosique.
Article for general public (2005)Detailed reference viewed: 4 (0 ULg)
Les perspectives d'harmonisation du droit de la construction
Conference (2010, November 18)Detailed reference viewed: 18 (3 ULg)
Perspectives d'utilisation de la tomographie dans la description du fonctionnement des réacteurs à trois phases
Toye, Dominique ; Crine, Michel ; Marchot, Pierre et al
Scientific conference (1997, June 19)Detailed reference viewed: 4 (0 ULg)
Perspectives de développement de la production de poulets de chair en Région Wallonne.
Conference given outside the academic context (1999)Detailed reference viewed: 5 (0 ULg)