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See detailImpact of aortic stenosis severity and its interaction with prosthesis-patient mismatch on operative mortality following aortic valve replacement.
Girerd, N.; Dumesnil, J. G.; Magne, Julien ULg et al

in Journal of Heart Valve Disease (The) (2012), 21(2), 158-167

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See detailImpact of aortic stiffness on left ventricular function and B-type natriuretic peptide release in severe aortic stenosis.
Rosca, M.; Magne, Julien ULg; Calin, A. et al

in European Journal of Echocardiography (2011), 12(11), 850-856

Aims: In aortic stenosis (AS), both reduced systemic arterial compliance and increased valvular load have been shown to contribute to impaired left ventricular (LV) function. However, the relationship ... [more ▼]

Aims: In aortic stenosis (AS), both reduced systemic arterial compliance and increased valvular load have been shown to contribute to impaired left ventricular (LV) function. However, the relationship between LV function and aortic stiffness has not yet been investigated. We aimed to assess the relationship between aortic stiffness and LV global longitudinal strain (GLS), LV filling pressures (E/E′) and B-type natriuretic peptide (BNP) in AS. <br />Methods and results : A comprehensive echocardiogram was performed in 48 consecutive patients with severe AS (,0.6 cm2/m2) and preserved LV ejection fraction (≥50%). Aortic stiffness index (beta) was calculated based on aortic diameters measured by echocardiography and blood pressure. Systemic arterial compliance (SAC) and valvulo-arterial impedance (Zva) <br />were also determined. Aortic beta index was significantly correlated with Zva (r ¼ 0.30, P ¼ 0.03) and SAC (r ¼ 20.29, P ¼ 0.04). GLS (r ¼ 0.45, P ¼ 0.001), E/E′ (r ¼ 0.48, P ¼ 0.001) and BNP levels (r ¼ 0.45, P ¼ 0.001) were significantly related to aortic beta index. No significant correlation was found between GLS or E/E′ and SAC or Zva. In multivariate regression analysis, aortic beta index remained correlated with GLS, E/E′, and BNP levels. <br />Conclusions : In patients with severe AS and preserved LV ejection fraction, independently of the valvular load, an increase in aortic rigidity, as assessed by aortic beta index, is independently correlated with reduced LV longitudinal function, increased LV filling pressures, and BNP levels. [less ▲]

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See detailImpact of aortic valve stenosis on left atrial phasic function
O'Connor, K.; Magne, Julien ULg; Rosca, M. et al

in American Journal of Cardiology (2010), 106(8), 1157-1162

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See detailImpact of Aphasia on Consciousness Assessment: A Cross-Sectional Study.
Schnakers, C; Bessou, H; Rubi-Fessen, I et al

in Neurorehabilitation & Neural Repair (2015), 29

BACKGROUND: . Previous findings suggest that language disorders may occur in severely brain-injured patients and could interfere with behavioral assessments of consciousness. However, no study ... [more ▼]

BACKGROUND: . Previous findings suggest that language disorders may occur in severely brain-injured patients and could interfere with behavioral assessments of consciousness. However, no study investigated to what extent language impairment could affect patients' behavioral responses. OBJECTIVE: . To estimate the impact of receptive and/or productive language impairments on consciousness assessment. METHODS: . Twenty-four acute and subacute stroke patients with different types of aphasia (global, n = 11; Broca, n = 4; Wernicke, n = 3; anomic, n = 4; mixed, n = 2) were recruited in neurology and neurosurgery units as well as in rehabilitation centers. The Coma Recovery Scale-Revised (CRS-R) was administered. RESULTS: . We observed that 25% (6 out of 24) of stroke patients with a diagnosis of aphasia and 54% (6 out of 11) of patients with a diagnosis of global aphasia did not reach the maximal CRS-R total score of 23. An underestimation of the consciousness level was observed in 3 patients with global aphasia who could have been misdiagnosed as being in a minimally conscious state, even in the absence of any documented period of coma. More precisely, lower subscores were observed on the communication, motor, oromotor, and arousal subscales. CONCLUSION: . Consciousness assessment may be complicated by the co-occurrence of severe language deficits. This stresses the importance of developing new tools or identifying items in existing scales, which may allow the detection of language impairment in severely brain-injured patients. [less ▲]

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See detailImpact of aphid alarm pheromone release on virus transmission efficiency: when pest control strategy could induce higher virus dispersion
Lin, Fang-Jing; Bosquée, Emilie ULg; Liu, Ying-Jie et al

in Journal of Virological Methods (2016)

Aphids cause serious damages to crops not only by tacking sap but also by transmitting numerous viruses. To develop biological control, the aphid alarm pheromone, namely E-β-farnesene (EβF), has been ... [more ▼]

Aphids cause serious damages to crops not only by tacking sap but also by transmitting numerous viruses. To develop biological control, the aphid alarm pheromone, namely E-β-farnesene (EβF), has been demonstrated to be efficient to repel aphids and as attract beneficials, making it a potential tool to control aphid pests. Considering aphids also as virus vectors, changes of their behaviour could also interfere with the virus acquisition and transmission process. Here, a combination of two aphid species and two potato virus models were selected to test the influence of EβF release on aphid and virus dispersion under laboratory conditions. EβF release was found to significantly decrease the population of M. persicae and M. euphorbiae around the infochemical releaser but simultaneously also increasing the dispersal of Potato Virus Y (PVY). At the opposite, no significant difference for Potato Leaf Roll Virus (PLRV) transmission efficiency was observed with similar aphid alarm pheromone releases for none of the aphid species. These results provide some support to carefully consider infochemical releasers not only for push – pull strategy and pest control but also to include viral disease in a the plant protection to aphids as they are also efficient virus vectors. Impact of aphid kinds and transmission mechanisms will be discussed according to the large variation found between persistent and non persistent potato viruses and interactions with aphids and related infochemicals. [less ▲]

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See detailThe impact of architectural representations on conveying design intent.
Cunin, Maxime; Yang, Maria C.; Elsen, Catherine ULg

in AI EDAM: Artificial Intelligence for Engineering Design Analysis and Manufacturing (in press)

Architects express themselves graphically in order to communicate ideas both to clients and to themselves. In practice, they rely on a variety of representations such as free-hand drawings, 3D computer ... [more ▼]

Architects express themselves graphically in order to communicate ideas both to clients and to themselves. In practice, they rely on a variety of representations such as free-hand drawings, 3D computer rendered images, and photomontages to convey their design intent. Research to date has demonstrated differences and commonalities in the ways in which expert designers and laymen perceive visual understanding. It is still unclear how architects themselves use different types of representations to express different intentions, and how accurately their expected audience perceives those intentions. The purpose of this research is to investigate how laymen interpret the initial design intent of an architect’s design, and what role different forms of representations play in this process of understanding a design. This paper describes a five-step process for developing a survey that was used to gather data from 686 laymen respondents. It was found that certain types of simpler representations presented in specific contexts are unexpectedly found to be a more efficient way to faithfully transmit an architectural intent. [less ▲]

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See detailThe Impact of Attentional Allocation Capacities on Nonword Repetition in Children with Specific Language Impairment
Leclercq, Anne-Lise ULg; Maillart, Christelle ULg; Lange, Manon et al

in Clinical Linguistics & Phonetics (2015)

This study aimed at directly assessing the hypothesis that attentional allocation capacity influences poor NWR performances in children with SLI, using an attention demanding visual search task given ... [more ▼]

This study aimed at directly assessing the hypothesis that attentional allocation capacity influences poor NWR performances in children with SLI, using an attention demanding visual search task given concurrently with the NWR task. Twenty-one children with SLI, 21 typically-developing children matched on age, and 21 typically-developing children matched on nonword span performed an immediate serial recall task of nonwords. The nonword lists were presented either alone or concurrently with the visual search task. Overall, results revealed a resource-sharing trade-off between the two tasks. Children with SLI were affected to the same extent as their span-matched controls by the necessity to allocate their attentional resources between the two tasks. Interestingly, nonword processing strategies seemed to differ among groups: age-matched controls allocated a larger part of their attentional resources to the encoding stage, while nonword recall was more attention demanding in children with SLI and younger controls. [less ▲]

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See detailImpact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: a free-response ROC analysis.
Hustinx, Roland ULg; Dolin, R. J.; Benard, F. et al

in European Journal of Nuclear Medicine (2000), 27(9), 1365-71

The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating ... [more ▼]

The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating characteristic (FROC) methodology. Thirty-four patients with various abdominal tumors were evaluated (11 men, 23 women, median age 48 years). Whole-body emission scans were performed 68 min (35-102 min) after intravenous injection of 4.3 MBq/kg fluorine-18 fluorodeoxyglucose (FDG). Images were reconstructed using the OS-EM algorithm and corrected for attenuation either using postinjection singles transmission (n=27) or by calculation and body outline (n=7). Total scan duration did not exceed 70 min. Studies were read independently by four observers unaware of any clinical data. The uncorrected (UC) images were systematically read before the attenuation-corrected (AC) images. All studies were given an image quality score ranging from 1 (unreadable) to 5 (excellent). Each focus of increased activity was then localized and given a probability of malignancy using a five-point scale. The average image quality score was similar for both UC and AC images. At the time of the positron emission tomography (PET) scans, 127 lesions (63 liver metastases, 9 retroperitoneal lesions, 50 peritoneal or bowel lesions, and 5 pancreatic carcinomas) were revealed by pathological or correlative studies. The areas under the FROC curves were consistently greater for AC images (range 0.8663-0.8867) than for UC images (range 0.7774 -0.8613). Overall, the difference between the AC images and the UC images was significant (P=0.019). In particular, correction for attenuation increased the sensitivity regardless of the location of the lesions. In conclusion, correction for attenuation significantly improves the diagnostic accuracy of FDG-PET for abdominal staging of neoplasms, without impairing the image quality. [less ▲]

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See detailImpact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: An ROC analysis.
HUSTINX, Roland ULg; DOLIN, RJ.; BENARD, F. et al

in Journal of Nuclear Medicine (The) (1999), 40

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See detailThe impact of auditory selective attention on verbal short-term memory and vocabulary development
Majerus, Steve ULg; Heiligenstein, Lucie; Gautherot, N. et al

in Journal of Experimental Child Psychology (2009), 103

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See detailImpact of Azacitidine before allogeneic stem-cell transplantation for myelodysplastic syndromes : a study b the Société Française de Greffe de Moelle et de Thérapie-Cellulaire and the Groupe Francophone des Myélodysplasies
Damaj, Gandhi; Duhamel, Alain; Robin, Marie et al

in Journal of Clinical Oncology (2012), 30

Purpose : To investigate the impact of prior-to-transplantation azacitidine (AZA) on patient outcome after allogeneic stem-cell transplantation (alloSCT) for myelodysplastic syndrome (MDS). Patients and ... [more ▼]

Purpose : To investigate the impact of prior-to-transplantation azacitidine (AZA) on patient outcome after allogeneic stem-cell transplantation (alloSCT) for myelodysplastic syndrome (MDS). Patients and Methods Of the 265 consecutive patients who underwent alloSCT for MDS between October 2005 and December 2009, 163 had received cytoreductive treatment prior to transplantation, including induction chemotherapy (ICT) alone (ICT group; n 98), AZA alone (AZA group; n 48), or AZA preceded or followed by ICT (AZA-ICT group; n 17). At diagnosis, 126 patients (77%) had an excess of marrow blasts, and 95 patients (58%) had intermediate-2 or high-risk MDS according to the International Prognostic Scoring System (IPSS). Progression to more advanced disease before alloSCT was recorded in 67 patients. Donors were sibling (n 75) or HLA-matched unrelated (10/10; n 88). They received blood (n 142) or marrow (n 21) grafts following either myeloablative (n 33) or reduced intensity (n 130) conditioning. Results : With a median follow-up of 38.7 months, 3-year outcomes in the AZA, ICT, and AZA-ICT groups were 55%, 48%, and 32% (P .07) for overall survival (OS); 42%, 44%, and 29% (P .14) for event-free survival (EFS); 40%, 37%, and 36% (P .86) for relapse; and 19%, 20%, and 35% (P .24) for nonrelapse mortality (NRM), respectively. Multivariate analysis confirmed the absence of statistical differences between the AZA and the ICT groups in terms of OS, EFS, relapse, and NRM. Conclusion : With the goal of downstaging underlying disease before alloSCT, AZA alone led to outcomes similar to those for standard ICT. [less ▲]

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See detailImpact of benevolent sexism on assessment of dangerousness by novice and expert policemen: a study by eye tracking
Blavier, Adelaïde ULg; Cardyn, Perrine; Gelon, Emilie et al

Conference (2013, May 28)

Our aim was to study how professional expertise may influence both visual perception of a scene and verbal judgment and how these 2 components interact and are influenced by benevolent sexism attitude. We ... [more ▼]

Our aim was to study how professional expertise may influence both visual perception of a scene and verbal judgment and how these 2 components interact and are influenced by benevolent sexism attitude. We studied how stereotype (here, benevolent sexism) influences both the eye movements and the verbal judgment according to the expertise. 3 groups of subjects (10 expert policemen-policewomen, 10 novice policemen-policewomen and 10 control subjects) answered to ASI questionnaire and assessed dangerousness of 15 images of domestic violence (individually and randomly presented). Eye movements were recorded while subjects looked at the domestic violence images. Our results showed the more benevolent sexist are the subjects (particularly the women), the more they looked at the victim and the lower they assessed the dangerousness. Moreover, novices answered more slowly and assessed ambiguous situations as more dangerous than experts. The differences between novices and experts were more important for women than for men, suggesting that professional experience has a stronger impact on women than men. Our findings confirm our main hypothesis suggesting sexism influences the visual analysis of a scene and thus the judgment attributed to the scene. Moreover, it seems professional experience does not modify the stereotype, particularly for benevolent sexist men. The discussion of all our results emphasizes their implication for a better understanding of our visual cognitive system (particularly the interaction between low-level visual analysis by eye movements and verbal judgment) and for the training of policemen (by taking into account the importance of their stereotype in complex interventions). [less ▲]

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See detailImpact of biomaterial microtopography on bone regeneration: comparison of three hydroxyapatites
LAMBERT, France ULg; Bacevic, Miljana ULg; Layrolle, Pierre et al

in Clinical Oral Implants Research (2016)

Aims: The primary objective of this study was to compare the in vivo performance, namely in terms of quantity of newly formed bone and bone-to-material contact (osteoconductivity), of three hydroxyapatite ... [more ▼]

Aims: The primary objective of this study was to compare the in vivo performance, namely in terms of quantity of newly formed bone and bone-to-material contact (osteoconductivity), of three hydroxyapatite-based biomaterials (HA) of different origins (natural or synthetic) or manufacturing process in a sinus lift model in rabbits. The secondary objective was to correlate the findings with the physical and topographical characteristics of the biomaterials. Materials and Methods: Two bovine HA manufactured with different processes (bovine hydroxyapatites [BHA] and cuttlebone hydroxyapatite [CBHA]) and a synthetic hydroxyapatite (SHA) sintered at high temperature were characterised with scanning electronic microscopy (SEM) and the measurement of specific surface area (BET). The materials were implanted in a sinus lift model in rabbits; histological and histomorphometric evaluation using non-decalcified sections was performed at 1, 5 and 12 weeks after implantation. Results: The studied biomaterials displayed a different surface topography. The two natural HA displayed significantly higher bone quantities (P = 0.0017; BHA vs. SHA, P = 0.0018 and CBHA vs. SHA, P = 0.033) at 5 and 12 weeks compared to the synthetic one (SHA). Moreover, the osteoconductivity (bone-to-material contact) was significantly higher in the BHA group compared to the two other groups (P = 0.014; BHA vs. SHA, P = 0.023 and BHA vs. CBHA, P = 0.033). Conclusion: HA-based biomaterials from diverse origins and manufacturing processes displayed different topographical characteristics. This may have influenced different regenerated bone architecture observed; more bone was found with natural HA compared to the synthetic one, and significantly higher bone-to-material contacts were found with BHA. [less ▲]

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See detailImpact of biomaterial physical characteristics on bone regeneration: Comparison of three hydroxyapatites
LAMBERT, France ULg; Bacevic, Miljana ULg; Schupbach, P et al

Poster (2015, June 03)

Bone regeneration biomaterials with identical chemical compositions are frequently considered by clinicians as similar. However, the clinical performance of regenerative biomaterial may be influenced by ... [more ▼]

Bone regeneration biomaterials with identical chemical compositions are frequently considered by clinicians as similar. However, the clinical performance of regenerative biomaterial may be influenced by other parameters such as topographical properties. [less ▲]

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See detailImpact of biotechnology on animal breeding and genetic progress
Gengler, Nicolas ULg; Druet, Tom ULg

in Renaville, Robert; Burny, Arsène (Eds.) Biotechnology in Animal Husbandry (2001)

Animal breeding is a field related to a whole range of biotechnologies. The impact of a biotechnology can be measured by the influence it has on genetic progress. According to the type of biotechnology ... [more ▼]

Animal breeding is a field related to a whole range of biotechnologies. The impact of a biotechnology can be measured by the influence it has on genetic progress. According to the type of biotechnology considered, different component of genetic progress may be affected: accuracy of prediction, generation interval, intensity of selection and genetic variance. The first type of biotechnologies affects the efficiency of male and female reproduction: artificial insemination, multiple ovulation, in-vitro-fertilization, ova pick-up, embryo-transfer, twining, sexing of semen and embryos cloning and selfing. The impact of these technologies is mainly in the enhanced distribution of superior germplasm and the selection intensity, but also in the accuracy obtained when testing animals. In the past, artificial insemination has been a very successful biotechnology, enhancing greatly the genetic progress. A secondary, negative, impact is that these biotechnologies affect indirectly genetic diversity and therefore reduce genetic variance. A second group of biotechnologies can improve determination of the genetic merit of animals. These are all the techniques relate to quantitative or economical trait loci (QTL/ETL), their detection and use. Their main feature is the early availability in life, therefore allowing an earlier and more accurate selection. Two direction of research exists: detection of markers for the unknown QTL and direct use of a potential candidate genes as QTL/ETL. QTL/ETL will have a major impact on animal breeding especially if their use in future breeding programs can be optimized. A last type of biotechnologies with a large potential to affect animal breeding in the future are those with the ability to transform artificially DNA. The impact of these technologies is however still no very clear especially as gene expression and other issues remain unsolved. Biotechnology had, has and will have a major impact on animal breeding and genetic progress. To a certain extend animal breeding is a very promising field to use biotechnology as the past has already proven. [less ▲]

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See detailImpact of blindness onset on the functional organization and the connectivity of the occipital cortex
Collignon, Olivier; Dormal, Giulia; Albouy, Geneviève et al

in Brain : A Journal of Neurology (2013)

Detailed reference viewed: 34 (4 ULg)