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See detailMassive stars, a lifetime of influence
Nazé, Yaël ULg

Poster (2010)

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See detailMast cells: potential positive and negative roles in tumor biology.
Marichal, Thomas ULg; Tsai, Mindy; Galli, Stephen J.

in Cancer Immunology Research (2013), 1

Mast cells are immune cells that reside in virtually all vascularized tissues. Upon activation by diverse mechanisms, mast cells can secrete a broad array of biologically active products that either are ... [more ▼]

Mast cells are immune cells that reside in virtually all vascularized tissues. Upon activation by diverse mechanisms, mast cells can secrete a broad array of biologically active products that either are stored in the cytoplasmic granules of the cells (e.g., histamine, heparin, various proteases) or are produced de novo upon cell stimulation (e.g., prostaglandins, leukotrienes, cytokines, chemokines, and growth factors). Mast cells are best known for their effector functions during anaphylaxis and acute IgE-associated allergic reactions, but they also have been implicated in a wide variety of processes that maintain health or contribute to disease. There has been particular interest in the possible roles of mast cells in tumor biology. In vitro studies have shown that mast cells have the potential to influence many aspects of tumor biology, including tumor development, tumor-induced angiogenesis, and tissue remodeling, and the shaping of adaptive immune responses to tumors. Yet, the actual contributions of mast cells to tumor biology in vivo remain controversial. Here, we review some basic features of mast cell biology with a special emphasis on those relevant to their potential roles in tumors. We discuss how using in vivo tumor models in combination with models in which mast cell function can be modulated has implicated mast cells in the regulation of host responses to tumors. Finally, we summarize data from studies of human tumors that suggest either beneficial or detrimental roles for mast cells in tumors. [less ▲]

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See detailMastectomie bilaterale prophylactique chez les patientes a tres haut risque de cancer mammaire: au-dela de la technique...
BLERET, Valerie ULg; Cusumano, P.; DEZFOULIAN, Bahram ULg et al

in Revue Médicale de Liège (2011), 66(5-6), 250-3

Bilateral prophylactic mastectomy is the most efficient risk management strategy for women at very high risk for breast cancer. Different methods can be used. The implementation of such a strategy must ... [more ▼]

Bilateral prophylactic mastectomy is the most efficient risk management strategy for women at very high risk for breast cancer. Different methods can be used. The implementation of such a strategy must respond to the request of a well informed patient. [less ▲]

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See detailMaster Class on Migration and Integration
Martiniello, Marco ULg

Scientific conference (2010, January 28)

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See detailUn master en ligne sous la loupe
Poumay, Marianne ULg

in Distances et Savoirs (2006), 4(1),

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See detailMaster-narratives for science policy. The interplay of political discourses on Science in Wallonia.
Charlier, Nathan ULg

Conference (2014, September)

Both in Europe and in the United States, scientific research and science, technology and innovation (STI) policies have undergone profound changes for about thirty years. These transitions are often ... [more ▼]

Both in Europe and in the United States, scientific research and science, technology and innovation (STI) policies have undergone profound changes for about thirty years. These transitions are often framed along dichotomous lines : an ‘old regime’ characterized by strong public funding, independent academia and a linear conception of innovation has supposedly been replaced by a ‘new regime’ in which research and innovation are conceived in systemic terms, regarding their economic and societal relevance (Rip 2000). My proposal states that this conceptualization is of little use when it comes to studying the evolution of STI policies at the regional level. In this paper, I investigate how global master narratives like the “Knowledge-based Economy”, the “Grand societal Challenges”, “Science, the endless Frontier”, “Responsible Research and Innovation”, etc. are locally articulated, and thereby become grounded in regional STI policymaking, research, and innovation. These narratives, as explanatory resources and mobilizing resources, provide stakeholders with different visions; they are related to power relations between groups and individuals, to institutional settings and to policy trajectories. In my contribution, I study the four narratives in context; i.e. in different situated discourses of STI stakeholders. I consider multiple issues: who is telling what, to whom, why, when, where, and in which form. Instead of dichotomizing, investigating the evolutions of STI policies with a narrative framework provides an enriched description for complex local situations, towards a more political reading of the transitions. [less ▲]

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See detailMastercard challenges Decision of the European Commission before the European Court of first Instance
Partsch, Philippe-Emmanuel ULg

in Butterworths Journal of International Banking anf Financial Law (2008)

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See detailMastication-induced release of endotoxins in the bloodstream of periodontitis patients
Geerts, Sabine ULg; Nys, Monique; Legrand, Victor et al

Poster (1999)

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See detailMastitis risk indicators assessed through a germ specific epidemiological model in southern Belgium
Theron, Léonard ULg; Sustronck, Bart; Bertozzi, Carlo et al

Poster (2011, September 07)

Bovine mastitis is the most prevalent pathology in dairy production; in order to identify herd related risk indicators, our study focused on germ-specific approach to refine known risk indicators between ... [more ▼]

Bovine mastitis is the most prevalent pathology in dairy production; in order to identify herd related risk indicators, our study focused on germ-specific approach to refine known risk indicators between environmental or contagious epidemiologic models. We gathered clinical mastitis during 3 months in 21 walloon dairy farms representing 1630 Holstein cows (mean: 67; SD: 18). Farmers were interrogated by a questionnaire about their main practices and basic mastitis knowledge questions. Quarters and severity were recorded, sampled for bacteriology at day 0 and day 21 during 3 months. Individual cell counts were also recorded. Risk analysis included Odds ratio calculation (OR) and multivariate regression. The average prevalence of mastitis on the study was 3.25% (min 0.3%, max : 11.2%, SD : 2.8%) which is coherent with previous epidemiological studies in Wallonia. 124 quarters were sampled and non-negative bacteriology shown 45% of strictly environmental pathogens, 22% of strictly contagious pathogens and 33% of mix epidemiological model pathogens. Overall risk assessment revealed that cubicles free-stall herds shown mastitis lower incidence (OR = 0.49; IC95 [0.34-0.72]). Surprisingly, post-dipping appeared as an overall positive risk indicator for mastitis prevalence (OR =2.13; IC95 [2,13-3,39]). The germ specific approach revealed that Post-dipping was present in low incidence herds with contagious models (OR=0.29; IC95 [0.12-0.71]) and that the type of pathogen model is an interaction in post-dipping risk analysis (Breslow-Day test p<0.0001), whereas housing had no interaction with the model (p=0.33). In this way of categorizing variables, one is able to identify overall risk indicators or germ-specific model. This can lead to more accurate advices in farm consulting. [less ▲]

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See detailMAT_LSPIV 4.0: User Manual
Peltier, Yann ULg; Dewals, Benjamin ULg; Erpicum, Sébastien ULg et al

Software (2014)

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See detailThe mata'a and the "collapse hypothesis"
Flas, Damien ULg

in De Dapper, Morgan; Cauwe, Nicolas; Huyghe, Dirk (Eds.) Easter Island. Collapse or Transformation ? A State of the Art. Proceedings of the International Conference of Bruxelles (November 9th-10th 2012) (in press)

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See detailThe mata’a: typology, technology and function
Flas, Damien ULg

Conference (2012)

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See detailMatadine, a cytotoxic alkaloid from Strychnos gossweileri
Quetin-Leclercq, Joëlle; Coucke, P.; Delaude, Clément et al

in Phytochemistry (1991), 30(5), 1697-1700

Matadine, a new alkaloid, has been isolated from the root bark of Strychnos gossweileri. Elucidation of its structure is mainly based on 1H and 1D NMR studies. Its cytotoxic activity has been tested on ... [more ▼]

Matadine, a new alkaloid, has been isolated from the root bark of Strychnos gossweileri. Elucidation of its structure is mainly based on 1H and 1D NMR studies. Its cytotoxic activity has been tested on cancer cells and normal cells. Matadine is an anhydronium base as serpentine, that exerts also a selective inhibiting activity on B16 melanoma cells while it is less toxic in human 2002 non-cancer cells. This selective activity might be well due , as it seems to be the case for serpentine and alstonine, to a higher affinity of matadine for destabilized single-stranded DNA as mainly present in cancer cells. [less ▲]

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See detailMatadine: a New Anhydronium Base from Strychnos gossweileri
Quetin-Leclercq, J.; Warin, R.; Delaude, C. et al

in Planta Medica (1990), 56

Matadine was isolated from the root bark of Strychnos gossweileri collected by one of us (C.D.) in Matadi (Congo).We describe here the isolation and structure detrmination of a new anhydronium base to ... [more ▼]

Matadine was isolated from the root bark of Strychnos gossweileri collected by one of us (C.D.) in Matadi (Congo).We describe here the isolation and structure detrmination of a new anhydronium base to which we have given the trivial name of matadine. [less ▲]

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See detailMatched unrelated donor stem cell transplant in 131 patients with follicular lymphoma : an analysis from the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation
Avivi, Irit; Montoto, Silvia; Canals, Carme et al

in British Journal of Haematology (2009), 147

Matched unrelated donor stem cell transplantation (MUD-SCT) provides the only curative option for patients with follicular lymphoma (FL) who fail conventional therapies and do not have a siblong donor ... [more ▼]

Matched unrelated donor stem cell transplantation (MUD-SCT) provides the only curative option for patients with follicular lymphoma (FL) who fail conventional therapies and do not have a siblong donor. The purpose of this study was to analyse the outcome of patients with FL treated with MUD-SCT included in the European Group for Blood and Marrow Transplantation registry. 131 patients treated with reduced-intensity conditioning (RIC, n=87) or conventional myeloablative (CONV, n=44) MUD-SCT between 2000 and 2005 were included. Median time from diagnosis to MUD-SCT was 47 months and the median number of previous therapeutic regimens was 4 (previous autograft : 47%). RIC recipients were significantly older, with a longer interval from diagnosis to MUD-SCT and had failed a previous autograft more frequently than CONV recipients. Non-relapse mortality (NRM) was 24% and 30% at 100-d and 1-year, respectively. After a median follow-up of 36 months, 17% of the patients developed disease progression, the 3-year progression-freee survival (PFS) being 47%. Three-year overall survival (OS) for the whole series was 51%. On multivariate analysis, RIC regimens were associated with at lower NRM and a significantly longer PFS and OS. This retrospective study demonstrated that MUS-SCT results, even in heavily pre-treated populations, in a meaningful PFS and OS [less ▲]

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See detailMatching an oscillator model to a phase response curve
Sacré, Pierre ULg; Sepulchre, Rodolphe ULg

in Proceedings of the Joint 50th IEEE Conference on Decision and Control and European Control Conference (2011, December)

The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models. It is also an information often experimentally available to the biologist. This paper introduces a ... [more ▼]

The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models. It is also an information often experimentally available to the biologist. This paper introduces a numerical tool based on the sensitivity analysis of the PRC to adapt initial model parameters in order to match a particular PRC shape. We illustrate the approach on a simple biochemical model of circadian oscillator. [less ▲]

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See detailThe matching efficiency of regional labor markets. A stochastic production function estimation: France 1990-1995
Ibourk, Aomar; Maillard, Bénédicte; Perelman, Sergio ULg et al

in Empirica (2004), (31), 1-25

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of ... [more ▼]

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of variables meant to capture workers and firms characteristics. The model is estimated on French data covering twenty-two regions from March 1990 till February 1995. Our estimates suggest that aggregate matching efficiency has decreased steadily in the early nineties. There are also wide cross-regional differences. On average, about 30% of the variations of efficiency observed across time and regions can be related to changes in the explanatory variables used in the model. The most important explanatory variables are the proportion of youngsters, females and immigrants in the stock of job seekers. Long-term unemployment has a significant negative effect, population density a significant positive one. The huge decline in the proportion of permanent job offers has apparently little effect on matching efficiency. [less ▲]

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See detailMatching Grants and Unconditional Grants: The Case with n Goods
Jurion, Bernard ULg

in Public Finance = Finances Publiques (1979)

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See detailLe matérel archéologique des couches médiévales
Hoffsummer, Patrick ULg; Tilkin-Peters, Catherine

in Otte, Marcel (Ed.) Les fouilles de la place Saint-Lambert à Liège, 2: le Vieux-Marché (1988)

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