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See detailHearing “quack” and remembering a duck: Evidence for fluency attribution in young children
Geurten, Marie ULiege; Lloyd, Marianne; Willems, Sylvie ULiege

in Child Development (2017), 88(2), 514-522

Previous research has suggested that fluency does not influence memory decisions until age 7-8. In two experiments (n=96 and n=64, respectively), children, aged 4, 6, and 8 years (Experiment 1-2), and ... [more ▼]

Previous research has suggested that fluency does not influence memory decisions until age 7-8. In two experiments (n=96 and n=64, respectively), children, aged 4, 6, and 8 years (Experiment 1-2), and adults (Experiment 2) studied a list of pictures. Participants completed a recognition test during which each study item was preceded by a sound providing either a highly predictive or mildly predictive context in order to make some test items more conceptually fluent. Overall, highly predictive items were recognized at a higher rate than mildly predictive items demonstrating an earlier development of the fluency heuristic than previously observed. The study provides insight on how children develop metacognitive expectations and when they start to use them to guide their memory responses. [less ▲]

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See detailHeart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3).
Mouton, Veronique; Toussaint, Louise ULiege; Vertommen, Didier et al

in Biochemical Journal (2010), 431(2), 267-75

On the basis of transfection experiments using a dominant-negative approach, our previous studies suggested that PKB (protein kinase B) was not involved in heart PFK-2 (6-phosphofructo2-kinase) activation ... [more ▼]

On the basis of transfection experiments using a dominant-negative approach, our previous studies suggested that PKB (protein kinase B) was not involved in heart PFK-2 (6-phosphofructo2-kinase) activation by insulin. Therefore we first tested whether SGK3 (serum- and glucocorticoid-induced protein kinase 3) might be involved in this effect. Treatment of recombinant heart PFK-2 with [gamma-32P]ATP and SGK3 in vitro led to PFK-2 activation and phosphorylation at Ser466 and Ser483. However, in HEK-293T cells [HEK (human embryonic kidney)-293 cells expressing the large T-antigen of SV40 (simian virus 40)] co-transfected with SGK3 siRNA (small interfering RNA) and heart PFK-2, insulin-induced heart PFK-2 activation was unaffected. The involvement of PKB in heart PFK-2 activation by insulin was re-evaluated using different models: (i) hearts from transgenic mice with a muscle/heart-specific mutation in the PDK1 (phosphoinositide-dependent protein kinase 1)-substrate-docking site injected with insulin; (ii) hearts from PKBbeta-deficient mice injected with insulin; (iii) freshly isolated rat cardiomyocytes and perfused hearts treated with the selective Akti-1/2 PKB inhibitor prior to insulin treatment; and (iv) HEK-293T cells co-transfected with heart PFK-2, and PKBalpha/beta siRNA or PKBalpha siRNA, incubated with insulin. Together, the results indicated that SGK3 is not required for insulin-induced PFK-2 activation and that this effect is likely mediated by PKBalpha. [less ▲]

Detailed reference viewed: 44 (2 ULiège)
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See detailHeart failure assessment with a multiscale model
Negroni, Jorge; Cabrera-Fischer, Edmundo; Kosta, Sarah ULiege et al

Poster (2016, April 21)

Many cardiac diseases lead to heart failure (HF) causing increasing morbidity and mortality worldwide. Several alterations at the myocyte level have been identified, but their specific influence on ... [more ▼]

Many cardiac diseases lead to heart failure (HF) causing increasing morbidity and mortality worldwide. Several alterations at the myocyte level have been identified, but their specific influence on contractile and hemodynamic impairment is not yet clear. Mathematical modeling is a tool to address this issue enabling the analysis of individual myocyte changes on the overall circulatory response. Some myocyte models have been able to reproduce the impact of HF on experimentally detected myocyte components (1), but their integration into a ventricular model forming part of a multiscale circulatory approach has not been fully undertaken. Thus, the aim of this study is to compare the experimental hemodynamic and regional contractile response to acute HF versus a multiscale model based on a human myocyte representation. The experimentally-validated multiscale model shows adequate coupling between myocyte-derived left ventricular chamber and circulatory properties , and would be useful to predict the contractile and hemodynamic response to HF changes in myocyte variables. [less ▲]

Detailed reference viewed: 69 (5 ULiège)
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See detailHeart Graft Monitoring by the Ventricular Evoked Response
Mahaux, V.; Demoulin, J.C.; BIESSAUX, Yves ULiege et al

in Pacing & Clinical Electrophysiology (2000), 23(11, Pt 2), 2003-5

Monitoring of the negative slew rate of the evoked T wave has been proposed as a noninvasive diagnostic tool to follow heart transplant recipients. The clinical contribution of this measurement on ... [more ▼]

Monitoring of the negative slew rate of the evoked T wave has been proposed as a noninvasive diagnostic tool to follow heart transplant recipients. The clinical contribution of this measurement on telemetrically recorded, paced unipolar ventricular electrograms was evaluated in the detection of grade 3 acute allograft rejection. Thirteen patients undergoing heart transplantation received a DDD pacemaker connected to two epimyocardial leads. Electrograms were recorded and digitized after each endomyocardial biopsy (EMB). The maximum slew rate of the descending slope of the repolarization phase (RSP) was extracted and normalized. A 20% downward shift of RSP from the reference value was considered abnormal. Results of signal processing were blinded during the first 6 months. Eleven patients completed the 6 months blinded period and two patients died. A total of 101 EMB were graded according to the International Society for Heart and Lung Transplantation classification. Grade 3 was assigned to 9 EMB. A significant difference was found between RSP values measured during grade 3 rejection episodes and other RSP values (P < 0.001). A diagnostic model consisting of a single threshold test confirmed the ability of RSP to predict significant signs of rejection on EMB (P < 0.0001). The sensitivity of RSP in detecting grade 3 rejections was 100%, specificity was 81%, negative predictive value 100%, and positive predictive value 35%. The use of RSP as a noninvasive monitoring tool to pose the indication for a biopsy would avoid 73% of EMB. Monitoring of transplanted hearts based on the analysis of the ventricular evoked response is promising and may markedly reduce the number of EMB. [less ▲]

Detailed reference viewed: 17 (0 ULiège)
See detailHeart of Darkness: Notes
Maes-Jelinek, Hena ULiege

Book published by Longman (2001)

Detailed reference viewed: 14 (2 ULiège)
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See detailHeart rate and spontaneous work-rest cycles during exposure to heat
Vogt, J. J.; Libert, J. P.; Candas, V. et al

in Ergonomics (1983), 26(12), 1173-85

Detailed reference viewed: 23 (0 ULiège)
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See detailHeart rate and use of beta-blockers in stable outpatients with coronary artery disease.
Steg, Ph Gabriel; Ferrari, Roberto; Ford, Ian et al

in PLoS ONE (2012), 7(5), 36284

BACKGROUND: Heart rate (HR) is an emerging risk factor in coronary artery disease (CAD). However, there is little contemporary data regarding HR and the use of HR-lowering medications, particularly beta ... [more ▼]

BACKGROUND: Heart rate (HR) is an emerging risk factor in coronary artery disease (CAD). However, there is little contemporary data regarding HR and the use of HR-lowering medications, particularly beta-blockers, among patients with stable CAD in routine clinical practice. The goal of the present analysis was to describe HR in such patients, overall and in relation to beta-blocker use, and to describe the determinants of HR. METHODS AND FINDINGS: CLARIFY is an international, prospective, observational, longitudinal registry of outpatients with stable CAD, defined as prior myocardial infarction or revascularization procedure, evidence of coronary stenosis of >50%, or chest pain associated with proven myocardial ischemia. A total of 33,438 patients from 45 countries in Europe, the Americas, Africa, Middle East, and Asia/Pacific were enrolled between November 2009 and July 2010. Most of the 33,177 patients included in this analysis were men (77.5%). Mean (SD) age was 64.2 (10.5) years, HR by pulse was 68.3 (10.6) bpm, and by electrocardiogram was 67.2 (11.4) bpm. Overall, 44.0% had HR >/= 70 bpm. Beta-blockers were used in 75.1% of patients and another 14.4% had intolerance or contraindications to beta-blocker therapy. Among 24,910 patients on beta-blockers, 41.1% had HR >/= 70 bpm. HR >/= 70 bpm was independently associated with higher prevalence and severity of angina, more frequent evidence of myocardial ischemia, and lack of use of HR-lowering agents. CONCLUSIONS: Despite a high rate of use of beta-blockers, stable CAD patients often have resting HR >/= 70 bpm, which was associated with an overall worse health status, more frequent angina and ischemia. Further HR lowering is possible in many patients with CAD. Whether it will improve symptoms and outcomes is being tested. [less ▲]

Detailed reference viewed: 21 (1 ULiège)
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See detailHeart rate decrease induced by BPDZ 259, a diazoxide analogue
Damas, J.; Pirotte, Bernard ULiege

Poster (2000, November 18)

Detailed reference viewed: 18 (0 ULiège)
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See detailHeart rate variability as a measure of comfort in the anaesthetised horse
Lacroix, Alice; Gougnard, Alexandra ULiege; Cerri, Simona ULiege et al

Poster (2015)

Detailed reference viewed: 41 (9 ULiège)
See detailHeart rate variability in infants with obstructive sleep apnea
Massin, M. M.; Withofs, Nadia ULiege; Ravet, Françoise ULiege

in Archives de Pédiatrie (2002), 9(4), 444-445

Detailed reference viewed: 12 (0 ULiège)
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See detailHeart rate variability: a tool to explore the sleeping brain?
Chouchou, Florian; Desseilles, Martin ULiege

in Frontiers in neuroscience (2014), 8

Sleep is divided into two main sleep stages: (1) non-rapid eye movement sleep (non-REMS), characterized among others by reduced global brain activity; and (2) rapid eye movement sleep (REMS ... [more ▼]

Sleep is divided into two main sleep stages: (1) non-rapid eye movement sleep (non-REMS), characterized among others by reduced global brain activity; and (2) rapid eye movement sleep (REMS), characterized by global brain activity similar to that of wakefulness. Results of heart rate variability (HRV) analysis, which is widely used to explore autonomic modulation, have revealed higher parasympathetic tone during normal non-REMS and a shift toward sympathetic predominance during normal REMS. Moreover, HRV analysis combined with brain imaging has identified close connectivity between autonomic cardiac modulation and activity in brain areas such as the amygdala and insular cortex during REMS, but no connectivity between brain and cardiac activity during non-REMS. There is also some evidence for an association between HRV and dream intensity and emotionality. Following some technical considerations, this review addresses how brain activity during sleep contributes to changes in autonomic cardiac activity, organized into three parts: (1) the knowledge on autonomic cardiac control, (2) differences in brain and autonomic activity between non-REMS and REMS, and (3) the potential of HRV analysis to explore the sleeping brain, and the implications for psychiatric disorders. [less ▲]

Detailed reference viewed: 42 (0 ULiège)
See detailHeart rate, hematological and serum biochemical responses to show jumping
Lekeux, Pierre ULiege; Art, Tatiana ULiege; Linden, Annick ULiege et al

in Persson, S. G. B.; Lindholm, A.; Jeffcott, L. B. (Eds.) Equine Exercise Physiology III (1991)

Changes in heart rate (HR), plasma lactate (LA) and some other blood parameters were studied in 16 healthy show jumping horses participating in the Belgian Junior Championship. Venous blond was collected ... [more ▼]

Changes in heart rate (HR), plasma lactate (LA) and some other blood parameters were studied in 16 healthy show jumping horses participating in the Belgian Junior Championship. Venous blond was collected from each horse before and immediately after competing and was analysed for packed cell volume (PCV), LA, plasma cortisol, blood glucose (GLU), total plasma protein bicarbonate ions and serum levels of lactate dehydrogenase, creatine kinase, aspartate aminotransferase and gamma glutamyl transferase (GGT). A HR recorder placed under the saddle continuously recorded HR from the warm-up tu 5 min after the course in 10 horses. Show jumping induced a significant increase in all parameters, except GLU, which decreased significantly, and GGT which remained unchanged. Resting values of LA and HR were 0.43±0.05 mmol I-1 and 44.7±2.9 beau min-1 respectively. Post-exercise LA reached a mean value of 8.7±0.5 mmol I-1, while HR rose to a peak of 189.2±3.5 beau min-1 during Ihe course. The results of the present study demonstrated that, although the speed and duration of such an exercise are low, show jumping represents severe exertion which requires some anaerobic metabolism. [less ▲]

Detailed reference viewed: 150 (14 ULiège)
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See detailHeart structure and ventricular ultrastructure of hemoglobin- and myoglobin-free icefish Channichthys rhinoceratus
Feller, Georges ULiege; Goessens, G.; Gerday, Charles ULiege et al

in Cell & Tissue Research (1985), 242

Detailed reference viewed: 9 (1 ULiège)
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See detailHeart Team Liege - Session Video Link
PIERARD, Luc ULiege; vahanian, Alec; LANCELLOTTI, Patrizio ULiege et al

Conference (2016, September)

Detailed reference viewed: 116 (7 ULiège)
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See detailHeart Team Session
PIERARD, Luc ULiege; LANCELLOTTI, Patrizio ULiege; PETERMANS, Jean ULiege et al

Conference (2016, August)

Detailed reference viewed: 33 (3 ULiège)
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See detail"A Heart to Speak of": Authorial Sacrifice in Janet Frame's "Jan Godfrey" and Other Texts
Gabrielle, Cindy ULiege

in Commonwealth : Essays and Studies (2012), 34(2),

This essay examines Janet Frame's "Jan Godfrey" with a view to demonstrating that its author-figure writes a story that is not a story as long as she hesitates to grant her (re-) created Other full access ... [more ▼]

This essay examines Janet Frame's "Jan Godfrey" with a view to demonstrating that its author-figure writes a story that is not a story as long as she hesitates to grant her (re-) created Other full access to the speaking position she occupies. The idea explored in "Jan Godfrey," that non-stories of avoidance are in fact narratives of ontological decimation will, then, be shown to tie in with Frame’s belief that true art occurs at the edge of non-being. [less ▲]

Detailed reference viewed: 110 (4 ULiège)
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See detailHeart Valve Clinic: Rationale and Organization.
Lancellotti, Patrizio ULiege; Rosenhek, Raphael; Pibarot, Philippe

in The Canadian journal of cardiology (2014)

With an increasing prevalence of patients with valvular heart disease (VHD), a dedicated management approach delivered in a well-defined structure, namely, the heart valve clinic (HVC), is warranted. The ... [more ▼]

With an increasing prevalence of patients with valvular heart disease (VHD), a dedicated management approach delivered in a well-defined structure, namely, the heart valve clinic (HVC), is warranted. The HVC is made up of a multidisciplinary team with high expertise in the diagnosis, management, treatment, and surveillance of patients with VHD. The aim of the HVC is to provide the highest quality of care to patients with VHD to improve the level of adherence to current evidence and guidelines, quality of life, and short- and long-term outcomes. The HVC also provides help in (1) informing and educating patients to motivate them to take their prescribed medications and look out for signs indicating a worsening of their disease, (2) organizing meetings for updates in knowledge for modern management of patients with VHD, and (3) disseminating protocols of contemporary and good practice in VHD. [less ▲]

Detailed reference viewed: 29 (2 ULiège)
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See detailHeart valve disease (mitral valve disease): mitral regurgitation
LANCELLOTTI, Patrizio ULiege; DULGHERU, Raluca Elena ULiege; VANNAN, M. et al

in THE EACVI TEXTBOOK OF ECHOCARDIOGRAPHY - SECOND EDITION (2016)

Detailed reference viewed: 24 (3 ULiège)
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See detailHeart valve disease: (aorte valve disease): aortic regurgitation
TRIBOUILLOY, C; LANCELLOTTI, Patrizio ULiege; PETERS, F. et al

in THE EACVI TEXTBOOK OF ECHOCARDIOGRAPHY - SECOND EDITION (2016)

Detailed reference viewed: 13 (2 ULiège)