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See detailModelo de componentes para análise de ligações de madeira com ligadores metálicos
Cachim, Paulo; Franssen, Jean-Marc ULg

Conference (2011, June 07)

Connections are key elements in any structure because the knowledge of their behaviour is fundamental to an appropriate structural modelling since this behaviour can influence the distribution of efforts ... [more ▼]

Connections are key elements in any structure because the knowledge of their behaviour is fundamental to an appropriate structural modelling since this behaviour can influence the distribution of efforts in different structural elements. In the particular case of wood structures, connections are usually considered as completely rigid or hinged, but their actual behaviour is intermediate between these two extreme limits, depending on the geometry of the connection and the type of connector used. For the design of these connections, the methodology proposed by Eurocode 5 is based on plastic limit analysis which allows the determination of load strength of the connection but not the determination of its stiffness. For the determination of stiffness, Eurocode 5 presents just a very simple expression that depends only on the density of the wood and the diameter of connector to characterize the force-displacement behaviour, disregarding for this purpose the geometry of the connection or the angle of force in relation to the grain. The objective of this paper is to present a component model that allows the characterization of the behaviour of dowel type connections. The results obtained with the model were calibrated with experimental results obtained in the litterature. [less ▲]

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See detailModels and Analysis Tools for the Columbus Contamination Environment
De Leuze, Anne; Barbier, Christian ULg

Conference (1991)

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See detailModels and prospects for a sustainable suburban transition.
Marique, Anne-Françoise ULg; Reiter, Sigrid ULg

Conference (2013, July)

This paper addresses the challenges, transformations and conditions of a sustainable suburban transition. Two powerful levers are used: (1) urban form, which is considered in addition to the individual ... [more ▼]

This paper addresses the challenges, transformations and conditions of a sustainable suburban transition. Two powerful levers are used: (1) urban form, which is considered in addition to the individual building scale, and (2) mobility, because sprawl spatially separates activities, resulting in an increase in travel distances and energy used in transportation. Two main indicators (the heating needs of different types of suburban forms and a commute performance index) are developed and discussed. Three scenarios focused on the evolution of the existing building stock are modelled and assessed (the retrofitting of existing neighbourhoods, an increase in the built density and demolition / reconstruction) to answer two main questions: "how to intervene in suburban areas?" and" where to intervene? ". These main results focused on energy efficiency are then studied in a larger framework to highlight the opportunities, limitations, constraints and feasibility of each strategy. Concrete prospects and guidelines for policy makers are finally proposed to operationalize a "sustainable suburban renewal". These findings show that, beyond the traditional polarization of the debates on energy efficiency of our built environment between the “compact city” and the “sprawled city”, a new pragmatic paradigm, focused on the transition of suburban areas by densification, can make suburban areas evolve towards more sustainability. [less ▲]

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See detailModels for assessing the cost-effectiveness of the treatment and prevention of osteoporosis
Zethraeus, N.; Ben Sedrine, Wafa ULg; Caulin, F. et al

in Osteoporosis International (2002), 13(11), 841-857

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See detailModels for Decision Making: From Applications to Mathematics... and Back
Crama, Yves ULg

Conference (2010, March 15)

In this inaugural lecture, I describe some facets of the interplay between mathematics and management science, economics, or engineering, as they come together in operations research models. I intend to ... [more ▼]

In this inaugural lecture, I describe some facets of the interplay between mathematics and management science, economics, or engineering, as they come together in operations research models. I intend to illustrate, in particular, the complex and fruitful process through which fundamental combinatorial models find applications in management science, which in turn foster the development of new and challenging mathematical questions. [less ▲]

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See detailModels of co-production and social economy in service delivery in Europe
Defourny, Jacques ULg

Scientific conference (2011, June 08)

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See detailModels of irrigation system for Pursat basin planning
Ly, Sarann ULg; Someth, Paradis; Men, Nareth

Poster (2007, May 14)

The Mekong River and the Tonle Sap Great Lake in Cambodia have vast floodplain suitable for rice-based farming system. The Tonle Sap Basin, defined as the catchments of the Tonle Sap River at its ... [more ▼]

The Mekong River and the Tonle Sap Great Lake in Cambodia have vast floodplain suitable for rice-based farming system. The Tonle Sap Basin, defined as the catchments of the Tonle Sap River at its confluence with the Mekong River and other 11 main tributaries draining higher ground on all sides of the basin enclosing 44% of Cambodia’s land area. The Pursat River is one of tributaries of the Tonle Sap Great Lake. It originates at Cardamom Mountains and has very good potential for agricultural development. In this paper, we aim at applying three models of irrigation system for basin planning: Chinit (Dam-Reservoir Irrigation), West Baray (Reservoir Irrigation) and Batheay (Shallow Reservoir Irrigation) to Pursat Basin (one of sub-basin of the Tonle Sap Great Lake). Chinit Dam-Reservoir stores water supplied by one of tributaries of Tonle Sap Great Lake, the Chinit River, located in Kampong Thom Province. Spillway is built to pass up inundation and to release water to downstream part. The rest of water in the Dam-Reservoir is distributed to the paddy field by main canal, secondary canals and tertiary canals. This system can be put at the upstream part of the Pursat River, mountainous area. The West Baray Irrigation system is characterized by a reservoir combined with a dike system in the floodplain of the Tonle Sap Great Lake and an irrigation system situated in Siem Reap province. The reservoir is supplied by a tributary of the Tonle Sap Great Lake, the Siem Reap River, in rainy season. The water is distributed to irrigation area in dry season. A small dike system was constructed in the Tonle Sap floodplain for retarding and storing floodwater. The stored floodwater is used as an additional water source for dry season cultivation. This system can be placed at the central plain of the Pursat Basin. Batheay reservoir directly receives floodwater from the Mekong River. It functions as both a reservoir and a paddy field. In wet season, dike around the Batheay reservoir prevents floodwater from entering the reservoir. Rainy season rice is grown inside the reservoir. After harvesting, gates around the reservoir are opened to receive floodwater. The water is stored for cultivating dry season rice outside the reservoir. This system can be put at the downstream part of the Pursat River, floodplain area of Tonle Sap River. [less ▲]

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See detailModels to estimate overall analytical measurements uncertainty: assumptions, comparisons and applications
Rozet, Eric ULg; Rudaz, S.; Marini Djang'Eing'A, Roland ULg et al

in Analytica Chimica Acta (2011), 702

Evaluation of analytical results reliability is of core importance as crucial decisions are taken with them. From the various methodologies to evaluate the fitness of purpose of analytical methods ... [more ▼]

Evaluation of analytical results reliability is of core importance as crucial decisions are taken with them. From the various methodologies to evaluate the fitness of purpose of analytical methods, overall measurement uncertainty estimation is more and more applied. Overall measurement uncertainty allows to combine simultaneously the remaining systematic influences to the random sources of uncertainty and allows assessing the reliability of results generated by analytical methods. However there are various interpretations on how to estimate overall measurement uncertainty, and thus various models for estimating it. Each model together with its assumptions has great impacts on the risks to abusively declare that analytical methods are suitable for their intended purpose. This review paper aims at i) summarizing the various models used to estimate overall measurement uncertainty, ii) provide their pros and cons, iii) review the main areas of application and iv) as a conclusion provide some recommendations when evaluating overall measurement uncertainty. [less ▲]

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See detailModels to predict the combined effects of temperature and relative humidity on Pectobacterium Atrosepticum and Pectobacterium carotovorum subsp. Carotovorum population density and soft rot disease development at the surface of wounded potato tubers
Moh, Augustin; Massart, Sébastien ULg; Lepoivre, Philippe ULg et al

in Journal of Plant Pathology [=JPP] (2012), 94(1), 181-191

The main objectives of this study were to evaluate and model the influence of temperature (10, 15 and 20°C), relative humidity (86, 96 and 100%) and initial concentration of bacterial inoculum (105, 107 ... [more ▼]

The main objectives of this study were to evaluate and model the influence of temperature (10, 15 and 20°C), relative humidity (86, 96 and 100%) and initial concentration of bacterial inoculum (105, 107 et 109 CFU ml-1) on the population density of Pectobacterium atrosepticum (Pba) and Pectobacterium carotovorum subsp. carotovorum (Pcc) which are important potato pathogens in temperate climates, and on the development of soft rot symptoms caused by these bacteria at the surface of wounded potatoes tubers under controlled conditions. Experiments were carried out according to a Box-Behnken experimental design, simplifying prediction of the combined effects of three controlled factors. With both bacterial species, statistical analysis showed a significant effect of temperature, relative humidity and initially applied bacterial concentration on population dynamics and soft rot development at the surface of wounded potato tubers. Multiple regression analyses and the contour plots showed that the temperature is the most important factor, followed by the initially applied bacteria concentration and relative humidity. More than 64% of the variability of the soft rot symptoms observed could be explained by the presence of Pba and Pcc at the level of wounded potato tubers under the combined effect of tested factors. The quadratic polynomial models developed in our research should integrate the heterogeneity of tested bacteria belonging to the same species (which was not evaluated in this preliminary investigation) in further research. [less ▲]

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See detailModeltoets 1 : De Europese Talencertificaten : Certificaat Nederlands
Hennen, Karl-Heinz; Peters, Magda; Vromans, Joseph ULg

Book published by Weiterbildungs-Testsysteme (1998)

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See detailThe Modem contribution to Medalpex
Djenidi, Salim ULg; Nihoul, Jacques ULg; Clément, Francis et al

in Annales Geophysicae. Series B, Terrestrial and Planetary Physics (1987), 5B(1), 3-12

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See detailModena e la cittadinanza globale
Martiniello, Marco ULg

Scientific conference (2003, June 05)

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See detailModerate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors
Mangin, Floriane; Dilly, Sébastien ULg; Joly, Benoît ULg et al

in Bioorganic & Medicinal Chemistry Letters (2012)

The selectivity for 5-HT1A versus D4 receptors is significantly increased when the basic side chain of WAY-100635 is replaced by a 4-phenylpiperazine (3e) or a 4-phenyl-1,2,3,6-tetrahydropyridine moiety ... [more ▼]

The selectivity for 5-HT1A versus D4 receptors is significantly increased when the basic side chain of WAY-100635 is replaced by a 4-phenylpiperazine (3e) or a 4-phenyl-1,2,3,6-tetrahydropyridine moiety (3i). The 4-phenyl-1,2,3,6-tetrahydropyridine compounds (3i-l) have a higher affinity for 5-HT1A receptors than do the corresponding unsubstituted phenylpiperazine analogues (3e-h). Compounds 3e and 3i appear to be selective for 5-HT1A receptors over other relevant receptors and still behave as neutral antagonists. [less ▲]

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See detailModerate deflection analysis of shelles of revolution, using cylindrical components of the displacement
Debongnie, Jean-François ULg

Report (1984)

This paper is devoted to the analysis of shells of revolution, using cylindrical components of the displacement. This procedure, as coupled with a Fourier expansion by respect of the azimuth, permits the ... [more ▼]

This paper is devoted to the analysis of shells of revolution, using cylindrical components of the displacement. This procedure, as coupled with a Fourier expansion by respect of the azimuth, permits the generation of finite elements in which rigid body are represented exactly, even in the case of doubly curved shells. [less ▲]

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See detailModerate deglection analysis of shells of revolution, using cartesian components of the displacement
Debongnie, Jean-François ULg

Report (1985)

This paper is devoted to the analysis of shells of revolution, using cylindrical components of the displacement. This procedure, coupled with a Fourier expansion by respect of the azimuth, permits the ... [more ▼]

This paper is devoted to the analysis of shells of revolution, using cylindrical components of the displacement. This procedure, coupled with a Fourier expansion by respect of the azimuth, permits the generation of finite elements in which rigid body displacements are represented exactly, even in the case of doubly curved shells. [less ▲]

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See detailModerate hypothermia during cardiopulmonary bypass increases intramyocardial synthesis of heat shock protein 72.
Qing, Ma; Vazquez-Jimenez, Jaime F; Schumacher, Kathrin et al

in Journal of Thoracic and Cardiovascular Surgery (The) (2002), 124(4), 724-31

OBJECTIVES: This study was undertaken to test the hypothesis that the myocardial protective effect of moderate hypothermia during cardiopulmonary bypass involves upward regulation of heat shock protein 72 ... [more ▼]

OBJECTIVES: This study was undertaken to test the hypothesis that the myocardial protective effect of moderate hypothermia during cardiopulmonary bypass involves upward regulation of heat shock protein 72. METHODS: Sixteen young pigs were randomly assigned to a temperature regimen during standardized cardiopulmonary bypass of normothermia or moderate hypothermia (temperatures 37 degrees C and 28 degrees C, respectively, n = 8 per group). Myocardial probes were sequentially sampled from the right ventricle before and during bypass and 6 hours after bypass. Messenger RNA encoding for heat shock protein 72 was assessed by competitive reverse transcriptase-polymerase chain reaction, and heat shock protein 72 synthesis was assessed by Western blot and immunohistochemical methods. Induction of apoptosis was assessed by gene expression of apoptosis-regulating proteins (Bcl-xL, Bak, and Fas) according to competitive reverse transcriptase polymerase chain reaction. Apoptotic cells were identified with an in situ apoptosis-detection kit (terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling) in combination with morphologic criteria. Necrotic cells were detected by standard histologic methods. RESULTS: Moderate hypothermia rather than normothermia was associated with earlier and higher gene expression and synthesis of heat shock protein 72 in the myocardium during and after cardiac surgery. In the hypothermia group both heat shock protein 72 and the messenger RNA encoding it were detected as soon as 30 minutes after initiation of bypass and before aortic clamping, whereas in the normothermia group they were not detected before aortic clamping. Immunohistochemical methods showed localization of heat shock protein 72 in the cardiomyocytes, endothelial cells, and macrophages. Although the percentage of necrotic cells in the myocardium was lower in the hypothermic group, the induction of apoptosis regulatory proteins and the percentage of apoptotic cells did not differ between the groups. CONCLUSIONS: These results suggest that the myocardial protective effect of moderate hypothermia during cardiopulmonary bypass involves upward regulation of heat shock protein 72 and inhibition of necrosis but not of apoptosis. [less ▲]

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See detailModerate hypothermia during cardiopulmonary bypass reduces myocardial cell damage and myocardial cell death related to cardiac surgery.
Vazquez-Jimenez, J. F.; Qing, M.; Hermanns, B. et al

in Journal of the American College of Cardiology (2001), 38(4), 1216-23

OBJECTIVES: The goal of this study was to test the hypothesis that moderate hypothermia during cardiopulmonary bypass (CPB) provides myocardial protection by enhancing intra-myocardial anti-inflammatory ... [more ▼]

OBJECTIVES: The goal of this study was to test the hypothesis that moderate hypothermia during cardiopulmonary bypass (CPB) provides myocardial protection by enhancing intra-myocardial anti-inflammatory cytokine balance. BACKGROUND: Moderate hypothermia during experimental CPB stimulates production of interleukin-10 (IL10) and blunts release of tumor necrosis factor-alpha (TNFalpha). METHODS: Twelve young pigs were assigned to a temperature (T degrees ) regimen during CPB: moderate hypothermia (T degrees : 28 degrees C; n = 6) and normothermia (T degrees : 37 degrees C; n = 6). Intra-myocardial TNFalpha- and IL10-messenger RNA were detected by competitive reverse transcriptase polymerase chain reaction and quantification of cytokine synthesis by Western blot. Levels of cardiac troponin I (cTnI) in cardiac lymph and in arterial and coronary venous blood were examined during and after CPB. Myocardial cell damage was assessed by histologic and ultrastructural anomalies of tissue probes taken 6 h after CPB. RESULTS: Synthesis of IL10 was significantly higher, while that of TNFalpha was significantly lower, in pigs that were in moderate hypothermia during surgery than in the others. In contrast with normothermia, moderate hypothermia was also associated with significantly lower cumulative cardiac lymphatic flow during and after CPB, significantly lower lymphatic cTnI concentrations after CPB, significantly lower percentages of myocardial cell necrosis and a significantly lower score of ultrastructural anomalies of myocardial cells. While the percentage of apoptotic cells was not different between groups, the apoptosis/necrosis ratio tended to be higher in animals that were in moderate hypothermia during surgery. In all animals, TNFalpha synthesis correlated positively while IL10 production correlated negatively with necrosis and total cell death, respectively. CONCLUSIONS: Our results suggest that moderate hypothermia during CPB provides myocardial protection by enhancing intra-myocardial anti-inflammatory cytokine balance. [less ▲]

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See detailModerate patient-prosthesis mismatch can impact on mortality after aortic valve replacement
Dumesnil, J. G.; Magne, Julien ULg; Girerd, N. et al

in Heart (2009), 95(7), 592

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See detailA moderate transfusion regimen may reduce iron loading in beta-thalassemia major without producing excessive expansion of erythropoiesis.
Cazzola, M.; Borgna-Pignatti, C.; Locatelli, F. et al

in Transfusion (1997), 37(2), 135-40

BACKGROUND: Hypertransfusion with a baseline hemoglobin of 10 to 12 g per dL is still considered by many to be the mainstay of conservative therapy for beta-thalassemia major. However, this regimen is ... [more ▼]

BACKGROUND: Hypertransfusion with a baseline hemoglobin of 10 to 12 g per dL is still considered by many to be the mainstay of conservative therapy for beta-thalassemia major. However, this regimen is frequently associated with manifestations of transfusion iron overload, despite regular chelation therapy with subcutaneous desferoxamine. STUDY DESIGN AND METHODS: To verify whether a transfusion regimen with a target pretransfusion hemoglobin level between 9 and 10 g per dL can allow a significant reduction in blood consumption, while still effectively suppressing erythropoiesis, the records were reviewed of 32 beta-thalassemia major patients, who were maintained at a pretransfusion hemoglobin of 11.3 +/- 0.5 g per dL between 1981 and 1986. These patients were switched at the beginning of 1987 to a transfusion regimen with pretransfusion hemoglobin of 9.4 +/- 0.4 g per dL. The degree of erythroid marrow activity was evaluated in these patients and in 32 subjects with beta-thalassemia intermedia through the simple measurement of serum transferrin receptor. RESULTS: After the adoption of the moderate transfusion regimen, transfusion requirements decreased from 137 +/- 26 to 104 +/- 23 mL per kg per year of red cells (p < 0.0001), and mean serum ferritin decreased from 2448 +/- 1515 to 1187 +/- 816 micrograms per L (p < 0.0001), with one-half of patients achieving serum ferritin levels lower than 1000 micrograms per L. The proportion of patients having spontaneous pubertal development increased significantly (p < 0.01), as a result of less iron-related gonadotropin insufficiency. At the lower pretransfusion hemoglobin, erythroid marrow activity did not exceed two to three times normal levels in most subjects. CONCLUSION: As compared with hypertransfusion, moderate transfusion may allow more effective prevention of iron loading, with higher likelihood of spontaneous pubertal development and without producing excessive expansion of erythropoiesis. [less ▲]

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See detailModeration
Küpper, Achim ULg

Scientific conference (2012, October 10)

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