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See detailMaintenance and modernization works in the Belgian waterways network
Lejeune, André ULg; Pirotton, Michel ULg

in Internationales Wasserbausymposium Aachen 2000: Verkehrswasserbau (2000)

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See detailMaintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis
Reginster, Jean-Yves ULg; Kaufman, J. M.; Devogelaer, J. P. et al

in Arthritis and Rheumatism (2011), 63(S10), 436

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See detailMaintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis.
Reginster, Jean-Yves ULg; Kaufman, J. M.; Goemaere, S. et al

in Osteoporosis International (2012), 23

In an open-label extension study, BMD increased continuously with strontium ranelate over 10 years in osteoporotic women (P < 0.01). Vertebral and nonvertebral fracture incidence was lower between 5 and ... [more ▼]

In an open-label extension study, BMD increased continuously with strontium ranelate over 10 years in osteoporotic women (P < 0.01). Vertebral and nonvertebral fracture incidence was lower between 5 and 10 years than in a matched placebo group over 5 years (P < 0.05). Strontium ranelate's antifracture efficacy appears to be maintained long term. INTRODUCTION: Strontium ranelate has proven efficacy against vertebral and nonvertebral fractures, including hip, over 5 years in postmenopausal osteoporosis. We explored long-term efficacy and safety of strontium ranelate over 10 years. METHODS: Postmenopausal osteoporotic women participating in the double-blind, placebo-controlled phase 3 studies SOTI and TROPOS to 5 years were invited to enter a 5-year open-label extension, during which they received strontium ranelate 2 g/day (n = 237, 10-year population). Bone mineral density (BMD) and fracture incidence were recorded, and FRAX(R) scores were calculated. The effect of strontium ranelate on fracture incidence was evaluated by comparison with a FRAX(R)-matched placebo group identified in the TROPOS placebo arm. RESULTS: The patients in the 10-year population had baseline characteristics comparable to those of the total SOTI/TROPOS population. Over 10 years, lumbar BMD increased continuously and significantly (P < 0.01 versus previous year) with 34.5 +/- 20.2% relative change from baseline to 10 years. The incidence of vertebral and nonvertebral fracture with strontium ranelate in the 10-year population in years 6 to 10 was comparable to the incidence between years 0 and 5, but was significantly lower than the incidence observed in the FRAX(R)-matched placebo group over 5 years (P < 0.05); relative risk reductions for vertebral and nonvertebral fractures were 35% and 38%, respectively. Strontium ranelate was safe and well tolerated over 10 years. CONCLUSIONS: Long-term treatment with strontium ranelate is associated with sustained increases in BMD over 10 years, with a good safety profile. Our results also support the maintenance of antifracture efficacy over 10 years with strontium ranelate. [less ▲]

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See detailMaintenance of functional human cancellous bone and human hematopoiesis in NOD/SCID mice
Hubin, F.; Humblet, Chantal ULg; Belaid, Zakia ULg et al

in Cell Transplantation (2004), 13(7-8), 823-831

Attempts were made to establish models to study interactions between marrow stromal cells and hematopoietic cells in vivo. The approach was to create a NOD-SCID-hu murine model of long-term human ... [more ▼]

Attempts were made to establish models to study interactions between marrow stromal cells and hematopoietic cells in vivo. The approach was to create a NOD-SCID-hu murine model of long-term human hematopoiesis by implantation of a human adult bone fragment. Nine to 12 weeks posuransplantation, human CD45(+) cells were detected in the blood and the spleen of some mice. The histology of the human transplant showed that human bone fragment was viable at 9 weeks. Moreover, vessels of human origin, as assessed by immunohistochemical detection of human beta(2)-microglobulin, were observed in the mouse tissue surrounding the transplanted human fragment. [less ▲]

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See detailMaintenance of Remission Among Patients With Crohn's Disease on Antimetabolite Therapy After Infliximab Therapy Is Stopped.
Louis, Edouard ULg; Mary, J. Y.; Vernier-Massouille, G. et al

in Gastroenterology (2012), 142(1), 63-70531

BACKGROUND & AIMS: It is important to determine whether infliximab therapy can be safely interrupted in patients with Crohn's disease who have undergone a period of prolonged remission. We assessed the ... [more ▼]

BACKGROUND & AIMS: It is important to determine whether infliximab therapy can be safely interrupted in patients with Crohn's disease who have undergone a period of prolonged remission. We assessed the risk of relapse after infliximab therapy was discontinued in patients on combined maintenance therapy with antimetabolites and identified factors associated with relapse. METHODS: We performed a prospective study of 115 patients with Crohn's disease who were treated for at least 1 year with scheduled infliximab and an antimetabolite and had been in corticosteroid-free remission for at least 6 months. Infliximab was stopped, and patients were followed up for at least 1 year. We associated demographic, clinical, and biologic factors with time to relapse using a Cox model. RESULTS: After a median follow-up period of 28 months, 52 of the 115 patients experienced a relapse; the 1-year relapse rate was 43.9% +/- 5.0%. Based on multivariable analysis, risk factors for relapse included male sex, the absence of surgical resection, leukocyte counts >6.0 x 10(9)/L, and levels of hemoglobin </=145 g/L, C-reactive protein >/=5.0 mg/L, and fecal calprotectin >/=300 mug/g. Patients with no more than 2 of these risk factors (approximately 29% of the study population) had a 15% risk of relapse within 1 year. Re-treatment with infliximab was effective and well tolerated in 88% of patients who experienced a relapse. CONCLUSIONS: Approximately 50% of patients with Crohn's disease who were treated for at least 1 year with infliximab and an antimetabolite agent experienced a relapse within 1 year after discontinuation of infliximab. However, patients with a low risk of relapse can be identified using a combination of clinical and biologic markers. [less ▲]

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See detailMaintenance threonine requirement and efficiency of its use for accretion of whole-body threonine and protein in Atlantic salmon (Salmo salar L.) fry.
Rollin, Xavier; Wauters, Jean*-Baptiste; Bodin, Noe Lie et al

in British Journal of Nutrition (2006), 95(2), 234-45

Eighteen groups of seventy Atlantic salmon (Salmo salar L.) fry (initial mean body weight 0.8 (sd 0.01) g) were fed on semi-purified diets containing graded levels of l-threonine (Thr) in 15 litres ... [more ▼]

Eighteen groups of seventy Atlantic salmon (Salmo salar L.) fry (initial mean body weight 0.8 (sd 0.01) g) were fed on semi-purified diets containing graded levels of l-threonine (Thr) in 15 litres aquaria at a temperature of 14.5+/-1 degrees C. Doses of Thr represented 1, 31, 41, 51, 62, 72, 83 and 93 % of its ideal level for optimum protein deposition. Indispensable amino acids other than Thr were included in the same proportion (on a g/16 g N basis) as in the Atlantic salmon fry whole-body carcass. Following 36 d of feeding and a 36 h fast, fry were killed for whole-body protein and amino acid analysis. Weight gain (r2 0.98), protein accretion (r2 0.97), and Thr accretion (r2 0.97) were linear (P<0.01) functions of Thr intake. Slope of the Thr accretion regression line showed that the efficiency of Thr utilisation above maintenance was 76 %. At zero Thr intake, fry lost 5.4 mg Thr/kg body weight0.75 per d. The Thr maintenance requirement was 7.2 mg/kg body weight0.75 per d and the Thr requirement for growth was 66 mg for 1 g protein deposition. Increasing doses of Thr resulted in increased (P<0.05) concentrations of histidine and lysine, and decreased concentrations of isoleucine in whole-body protein. The maintenance need for Thr represented 13.4 % of the total need for Thr. The data suggest that efficiency of Thr utilisation above maintenance is constant at all levels of Thr intake between 1 and 93 % of the level required for optimum protein deposition. [less ▲]

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See detailMaintenance, entretien et réparation des constructions en béton
Courard, Luc ULg

Learning material (2009)

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See detailMaintenance/repair and production-oriented life cycle cost/earning model for ship structural optimization during conceptual design stage
Turan, Osman; Olcer, A. I.; Lazakis, Iraklis et al

in Ships & Offshore Structures (2009), 4(2), 107-125

The aim of this paper is to investigate the effect of the change in structural weight due to optimisation experiments on life cycle cost and earning elements using the life cycle cost/earning model, which ... [more ▼]

The aim of this paper is to investigate the effect of the change in structural weight due to optimisation experiments on life cycle cost and earning elements using the life cycle cost/earning model, which was developed for structure optimisation. The relation between structural variables and relevant cost/earning elements are explored and discussed in detail. The developed model is restricted to the relevant life cycle cost and earning elements, namely production cost, periodic maintenance cost, fuel oil cost, operational earning and dismantling earning. Therefore it is important to emphasise here that the cost/earning figure calculated through the developed methodology will not be a full life cycle cost/earning value for a subject vessel, but will be the relevant life cycle cost/earning value. As one of the main focuses of this paper is the maintenance/repair issue, the data was collected from a number of ship operators and was solely used for the purpose of regression analysis. An illustrative example for a chemical tanker is provided to show the applicability of the proposed approach. [less ▲]

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See detailMaintenir dans l'emploi le travailleur malade ou blessé : un défi !
Mairiaux, Philippe ULg

Conference (2010, November 25)

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See detailMaintenir la PTH entre 2 et 9 fois la valeur de référence supérieure du Laboratoire: d'accord, mais quelle valeur???
CAVALIER, Etienne ULg; DELANAYE, Pierre ULg; Souberbielle, Jean-Claude

in Néphrologie & Thérapeutique (2011, October), 7(5), 411-44727

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See detailMaintien d'une orientation spatio-temporelle chez une patiente Alzheimer: Utilisation conjointe d'un agenda et d'un téléphone portable
Quittre, Anne ULg; Adam, Stéphane ULg; Olivier, Catherine ULg et al

in Adam, Stéphane; Allain, Philippe; Aubin, Ghislaine (Eds.) et al Actualités en rééducation neuropsychologique: Etudes de cas (2009)

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See detailMaintien dans l'emploi des patients malades chroniques - pistes pour la collaboration des médecins impliqués
Mairiaux, Philippe ULg

Conference given outside the academic context (2013)

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See detailMaintien dans l'emploi des travailleurs âgés : enjeux et pistes de travail pour les entreprises
Bertrand, Françoise ULg; Hansez, Isabelle ULg; Peters, Stéphanie ULg

in Médecine du Travail & Ergonomie = Arbeidsgezondheidszorg & Ergonomie (2006), 42(3), 83-89

Le taux d’emploi des travailleurs âgés de plus de 55 ans en Belgique est un des plus faibles d’Europe. Notre pays est loin d’atteindre les objectifs de taux d’emploi inscrits dans la Stratégie Européenne ... [more ▼]

Le taux d’emploi des travailleurs âgés de plus de 55 ans en Belgique est un des plus faibles d’Europe. Notre pays est loin d’atteindre les objectifs de taux d’emploi inscrits dans la Stratégie Européenne de l’Emploi. Ce constat doit donc inciter les autorités publiques, les entreprises et les travailleurs à réagir. Si les premières ont commencé à mettre en place des mesures structurelles pour remédier au problème, les entreprises et les travailleurs ne sont pas toujours conscients de la marge de manœuvre dont ils disposent pour relever le défi. Les stéréotypes des unes et une certaine culture du « droit à la retraite » des autres sont des obstacles de première ligne. C’est pourquoi il est primordial d’engager des sensibilisations à leur égard. Cet article présente les résultats d’une recherche menée auprès de travailleurs belges pour évaluer les motifs de départ, et la place des conditions de travail et du stress dans l’explication des retraits prématurés. Les résultats fournissent un matériaux solide pour orienter non seulement la sensibilisation, mais aussi les actions à mettre en place au sein des entreprises pour encourager le maintien dans l’emploi des plus âgés. On notera par exemple que la prévention doit débuter avec les travailleurs dès l’âge de 46 ans, que la lutte contre le stress lié aux conditions de travail est nécessaire mais non suffisante pour prévenir les retraits prématurés, et qu’il faut surtout se concentrer sur une meilleure gestion des changements organisationnels et la valorisation du personnel pour endiguer les départs anticipés. [less ▲]

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See detailLe maintien dans l'emploi des travailleurs âgés ou la gestion des âges.
Bertrand, Françoise ULg; Hansez, Isabelle ULg; De Keyser, Véronique ULg

in Chasseigne, G.; Lassarre, D. (Eds.) Stress et Société. Volume III (2006)

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See detailLe maintien des "effets" des dispositions annulées par la Cour d’arbitrage : théorie et pratique
Rosoux, Géraldine ULg

in Liber Amicorum Paul Martens – L’humanisme dans la résolution des conflits. Utopie ou réalité ? (2007)

The article analyzes the competence of the Belgian constitutional court to maintain effects of the annuled legislative norm.

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See detailLe maintien des droits aux prestations de santé lors d'une séparation de fait ou de corps
Michiels, Olivier ULg

in Divorce : Actualité Juridique, Sociale et Fiscale (1997)

L'article examine la question du maintien des droits aux prestations de santé lors d'une séparation de corps ou d'une séparation de fait.

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See detailMaintien et stratégies de renforcement de la motivation des étudiants dans l'enseignement à distance
Mignon, Jacques ULg; Closset, Jean-Louis ULg

in Actes du 21e congrès de l’Association internationale de pédagogie universitaire (AIPU) (2004)

L'exploitation des nouvelles technologies dans la mise sur pied d'un enseignement à distance s'accompagne nécessairement d'une réflexion pédagogique structurée. Cette réflexion fait souvent fi de la mise ... [more ▼]

L'exploitation des nouvelles technologies dans la mise sur pied d'un enseignement à distance s'accompagne nécessairement d'une réflexion pédagogique structurée. Cette réflexion fait souvent fi de la mise en oeuvre de véritables stratégies motivationnelles. Pourtant, lorsqu'on demande à un enseignant pourquoi il souhaite mettre un cours en ligne, il invoque souvent le fait de chercher à motiver ses étudiants. Nous distinguerons ici le maintien de la motivation, du renforcement de la motivation des étudiants. Les risques de démotivation et d'abandon sont très nombreux dans l'enseignement à distance, même avec le soutien des nouvelles technologies. Il est donc essentiel de veiller à maintenir constamment la motivation initiale de l'apprenant. Si le maintien de cette motivation fait appel à des moyens, des trucs, des recettes de tutorat, il n'en va pas de même du renforcement de la motivation. En effet, il s'agit ici de mettre au point, dès la phase de conception du cours, de véritables stratégies motivationnelles. Quels sont les risques de démotivation des étudiants ? Comment les éviter ? Quelles bases théoriques peuvent nous guider dans notre mise au point des stratégies motivationnelles ? Quelles pistes motivationnelles le concepteur peut-il emprunter, et dans quelles perspectives ? Sur base des théories de la motivation, notre recension des données bibliographiques vise à préciser les questions que doivent se poser les concepteurs de cours à distance. De même, elle débouche, pour chaque question, sur des pistes concrètes à explorer. [less ▲]

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