Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
See detailManifestes!
Delville, Michel ULg

Article for general public (2010)

Detailed reference viewed: 24 (3 ULg)
Full Text
See detailManifold Utopia: The Novels of Janet Frame
Delrez, Marc ULg

Book published by Rodopi (2002)

Detailed reference viewed: 40 (14 ULg)
Full Text
See detailManipulating seed quality traits in pea (Pisum sativum L.) for improved feed and food
Vigeolas, Hélène ULg; Domoney, Claire; Charlton, A. et al

in Grain Legumes (2009), 52

Detailed reference viewed: 22 (4 ULg)
See detailManipulating the mitochondrial genome in the green alga Chlamydomonas reinhardtii
Remacle, Claire ULg

Scientific conference (2007, May)

Detailed reference viewed: 7 (1 ULg)
See detailManipulating tissue metabolism by amino acids
Tesseraud, S.; Everaert, Nadia ULg; Boussaid-Om Ezzine, S. et al

Conference (2010)

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailManipulating tissue metabolism by amino acids
Tesseraud, S.; Everaert, Nadia ULg; Boussaid-Om Ezzine, S. et al

in World's Poultry Science Journal (2011), 67(2), 243-251

Protein metabolism is considered to be regulated by amino acids, with major consequences on tissue development. There is evidence that lysine greatly affects carcass composition and muscle growth. In ... [more ▼]

Protein metabolism is considered to be regulated by amino acids, with major consequences on tissue development. There is evidence that lysine greatly affects carcass composition and muscle growth. In particular, a drastic effect of dietary provision of lysine has been observed on breast muscle development in chickens. Other essential amino acids, such as threonine and valine, do not have as pronounced an effect as lysine on body composition. Increasing lysine can also improve chicken breast muscle quality by increasing its ultimate pH and water holding capacity, but the underlying mechanisms are still unknown. Studies conducted over the last ten years indicate that, in addition to being substrates for protein synthesis, amino acids act as modulators of signal transduction pathways that control metabolism and cell functions. For instance, certain amino acids can modulate the activity of the intracellular protein kinases involved in the control of mRNA translation. Interestingly, enhanced responses to amino acids have been reported during the neonatal period, suggesting that early protein nutrition impacts on the development of broiler chicks. Methionine and cysteine have a very significant place among amino acids because they have several additional roles: they are precursors of essential molecules, for example cysteine is used for the synthesis of the antioxidant glutathione, and thus participates in the control of oxidative status, methionine is a source of the methyl groups needed for all biological methylation reactions, including methylation of DNA and histones, etc. These findings together indicate the importance of optimizing amino acid nutrition and providing a rationale for nutritional advice. © Copyright World's Poultry Science Association 2011. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailManipulation of Droplets onto a Planar Interface
Gilet, Tristan ULg; Terwagne, Denis ULg; Vandewalle, Nicolas ULg et al

in miller, reinhard; liggieri, libero (Eds.) Progress in Colloid and Interface Science, 2 (2011)

Detailed reference viewed: 54 (12 ULg)
Full Text
Peer Reviewed
See detailManipulation of the vortex motion in nanostructured ferromagnetic/superconductor hybrids
Silhanek, Alejandro ULg; Gillijns, W.; Moshchalkov, V. V. et al

in Applied Physics Letters (2007), 90(18),

The authors investigate the rectified motion of vortices in superconducting films deposited on top of a close-packed array of open in-plane magnetized triangular micromagnets. The dc voltage induced by ... [more ▼]

The authors investigate the rectified motion of vortices in superconducting films deposited on top of a close-packed array of open in-plane magnetized triangular micromagnets. The dc voltage induced by the vortex drift under an ac excitation is recorded for three different magnetic configurations of the triangles. When the magnetic elements are in the as-grown state a rectification signal which reverses sign when the field changes polarity is observed. In contrast to that, when the array of triangles is magnetized the observed rectification effect is independent of the field polarity and can be reverted by reorienting the magnetization of the micromagnets. (C) 2007 American Institute of Physics. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailManipulation photopériodique des saisons de reproduction chez le barbeau (Barbus barbus)
Poncin, Pascal ULg; Castelli, M.

in Cahiers d'Ethologie (1990), 10(3-4), 447-450

Pendant deux ans nous avons soumis quatre lots expérimentaux de barbeaux mâles et femelles d'élevage à différentes photopériodes artificielles, permettant une production quasi continue de larves. Celles ... [more ▼]

Pendant deux ans nous avons soumis quatre lots expérimentaux de barbeaux mâles et femelles d'élevage à différentes photopériodes artificielles, permettant une production quasi continue de larves. Celles-ci ont été élevées en eau réchauffée et utilisées pour l'expérimentation en génétique, le repeuplement des rivières et la commercialisation. [less ▲]

Detailed reference viewed: 28 (4 ULg)
Full Text
Peer Reviewed
See detailManipulations chromosomiques. Amélioration génétique et contrôle du sexe chez les poissons.
Castelli M.; Mélard, Charles ULg; Poncin, Pascal ULg et al

in Nouvelles de la Science et des Technologies (1990), 8(2), 61-71

Detailed reference viewed: 49 (8 ULg)
See detailLes manipulations des médias
Geuens, Geoffrey ULg

Conference given outside the academic context (2001)

Atelier d'éducation aux médias

Detailed reference viewed: 21 (11 ULg)
Full Text
Peer Reviewed
See detailMannheimia haemolytica leukotoxin-induced cytolysis of caprine (Capra hircus) leukocytes is mediated by the CD18 subunit of beta2-integrins
Fett, Thomas ULg; Zecchinon, Laurent ULg; Vanden Bergh, Philippe ULg et al

in Microbial Pathogenesis (2008), 45

Mannheimiosis is the major respiratory disease among some ruminants, whereas it is not pathogenic for other mammals, an observation that has been attributed to a specific interaction between Mannheimia ... [more ▼]

Mannheimiosis is the major respiratory disease among some ruminants, whereas it is not pathogenic for other mammals, an observation that has been attributed to a specific interaction between Mannheimia haemolytica leukotoxin (Lkt) and bovine or ovine CD18 subunit of lymphocyte function-associated antigen-1 (LFA-1) and Mac-1. We therefore hypothesized that Lkt utilizes CD18 as its receptor on caprine leukocytes as well. We have transiently transfected the b2-integrins-deficient K-562 cell line with cDNAs encoding caprine CD11a and caprine CD18 to determine the susceptibility of the transfectants to Lktinduced cytolysis. Flow cytometric analysis of the transfectants revealed surface expression of caprine LFA-1 and lysis by Lkt in a concentration-dependent manner whereas the parent cells were not. Moreover, K562 cells expressing caprine CD18 and human or bovine CD11a were also sensitive to Lkt whereas K-562 cells expressing caprine CD11a and human CD18 were not. Taken together, these results indicate that CD18 on caprine leukocytes serves as a receptor for Lkt. [less ▲]

Detailed reference viewed: 20 (8 ULg)
Full Text
Peer Reviewed
See detailLa mannheimiose : d’une liaison (moléculaire) fatale à une des principales maladies d’élevage des ruminants
Fett, Thomas ULg; Zecchinon, Laurent; Vanden Bergh, Philippe et al

in Annales de Médecine Vétérinaire (2009), 153(1), 31-53

Les pneumonies bactériennes constituent un problème majeur dans l'élevage et l'engraissement des bovins, avec des répercussions très élevées en termes de morbidité et de mortalité. Parmi les différentes ... [more ▼]

Les pneumonies bactériennes constituent un problème majeur dans l'élevage et l'engraissement des bovins, avec des répercussions très élevées en termes de morbidité et de mortalité. Parmi les différentes causes biologiques recensées, Mannheimia haemolytica tient le haut de l’affiche puisqu’elle est connue comme agent pathogène compliquant principal, voire systématique. Une de ses particularités est qu’elle ne déclenche de pneumonie broncho-alvéolaire fibrino-hémorragique que chez les ruminants. Les lésions observées résultent d’une nécrose en masse des neutrophiles et macrophages et du relarguage de leurs différents constituants. Au niveau moléculaire, cette spécificité trouve son origine dans l’intimité de la liaison entre la leucotoxine, le facteur de virulence majeur de la bactérie, et la sous-unité CD18 des récepteurs de surface leucocytaires bêta2-intégrines. La revue décrit cette liaison et ses conséquences aux niveaux macroscopique et microscopique, avant de faire le point sur les dernières avancées de la recherche et d’ébaucher quelques perspectives thérapeutiques. [less ▲]

Detailed reference viewed: 9 (1 ULg)
Full Text
See detailMannosylated amphiphilic and degradable PEO-b-PCL copolymers for drug delivery systems: preparation and sugar availability characterizations
Freichels, Hélène ULg; Imberty, Anne; Auezély-Velty, Rachel et al

Poster (2009, May 14)

Over the last decade, polymer micelles and nanoparticles attracted an increasing interest in pharmaceutical research because they can be used as efficient drug delivery systems. In this field, amphiphilic ... [more ▼]

Over the last decade, polymer micelles and nanoparticles attracted an increasing interest in pharmaceutical research because they can be used as efficient drug delivery systems. In this field, amphiphilic copolymers combining poly(ethylene oxide) and aliphatic polyester (such as poly(ε-caprolactone) (PCL) or polylactide (PLA)) are particularly of interest because (i) PEO has unique protein- repellent properties and thus provides a stealth behaviour to the drug carriers and (ii) aliphatic polyesters are biocompatible and biodegradable hydrophobic matrices well-suited for the incorporation of an hydrophobic drug. By end-capping the hydrophilic segment by a targeting moiety so that they may interact with membrane receptors, the biodistribution of polymeric micelles and nanoparticles stabilized with this copolymer can be modulated and can induce specific cellular uptake by receptor-mediated endocytosis. One class of interesting targeting agent is the saccharides, in particular the mannose, because of its specific interaction with mannose receptor, which are found on peripheral and bone marrow macrophages, dendritic cells and sinusoidal liver cells. In this study, the reductive amination reaction is use to attach this targeting agent. After optimisation of the reaction with amino fluorescein, a model amine, mannosylated copolymer of PEO and PCL has been prepared. The surface availability of the saccharide upon the micelles in aqueous phosphate buffer was then assessed by DLS through binding with the protein Concanavalin A (ConA), a known mannose receptor. The interactions between the Bcla lectin and the mannosylated micelles have then been studied by Isothermal Titration Calorimetry (ITC) and the thermodynamic parameters have been obtained. This polymer is particularly useful for the stabilization of PLGA nanoparticles with the goal to target M cells for oral vaccination. [less ▲]

Detailed reference viewed: 68 (10 ULg)
Full Text
Peer Reviewed
See detailMannosylated poly(ethylene oxide)-b-Poly(epsilon-caprolactone) diblock copolymers: Synthesis, characterization, and interaction with a bacterial lectin
Rieger, Jutta ULg; Stoffelbach, François; Cui, Di et al

in Biomacromolecules (2007), 8(9), 2717-2725

A novel bioeliminable amphiphilic poly(ethylene oxide)-b-poly(epsilon-caprolactone) (PEO-b-PCL) diblock copolymer end-capped by a mannose residue was synthesized by sequential controlled polymerization of ... [more ▼]

A novel bioeliminable amphiphilic poly(ethylene oxide)-b-poly(epsilon-caprolactone) (PEO-b-PCL) diblock copolymer end-capped by a mannose residue was synthesized by sequential controlled polymerization of ethylene oxide and epsilon-caprolactone, followed by the coupling of a reactive mannose derivative to the PEO chain end. The anionic polymerization of ethylene oxide was first initiated by potassium 2-dimethylaminoethanolate. The ring-opening polymerization of epsilon-caprolactone was then initiated by the omega-hydroxy end-group of PEO previously converted into an Al alkoxide. Finally, the saccharidic end-group was attached by quaternization of the tertiary amine (alpha-end-group of the PEO-b-PCL with a brominated mannose derivative. The copolymer was fully characterized in terms of chemical composition and purity by high-resolution NMR spectroscopy and size exclusion chromatography. Furthermore, measurements with a pendant drop tensiometer showed that both the mannosylated copolymer and the non-mannosylated counterpart significantly decreased the dichloromethane/water interfacial tension. Moreover, these amphiphilic copolymers formed monodisperse spherical micelles in water with an average diameter of similar to 11 nin as measured by dynamic light scattering and cryo-transmission electron microscopy. The availability of mannose as a specific recognition site at the surface of the micelles was proved by isothermal titration microcalorimetry (ITC), using the BclA lectin (from Burkholderia cenocepacia), which interacts selectively with a-D-mannopyranoside derivatives. The thermodynamic parameters of the lectin/mannose interaction were extracted from the ITC data. These colloidal systems have great potential for drug targeting and vaccine delivery systems. [less ▲]

Detailed reference viewed: 65 (4 ULg)
Peer Reviewed
See detailManoeuvrability of ships in shallow and restricted waters
Marchal, Jean ULg

Conference (1993, September)

Detailed reference viewed: 20 (4 ULg)
See detailManoscritti teatrali della Biblioteca Riccardiana di Firenze.
Moreno, Paola ULg

in Scriptorium (1999)

Detailed reference viewed: 14 (0 ULg)