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See detailAnticoagulants oraux : nouveaux horizons
PETERS, Pierre ULg; DEFRAIGNE, Jean ULg; GOTHOT, André ULg

in Revue Médicale de Liège (2012), 67

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See detailL'anticoagulation de l'hémofiltration continue: Citrate versus Héparine
Damas, Pierre ULg; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2007), 62

L'insuffisance rénale aiguë aux Soins Intensifs affecte un patient sur cinq et souvent nécessite le recours à une épuration extra-rénale. L'hémofiltration continue est choisie pour certains patients ... [more ▼]

L'insuffisance rénale aiguë aux Soins Intensifs affecte un patient sur cinq et souvent nécessite le recours à une épuration extra-rénale. L'hémofiltration continue est choisie pour certains patients (instabilité hémodynamique, neurologique, mais nécessite, comme d'ailleurs l'hémodialyse, une anticoagulation. Le citrate, utilisé dans le travail publié, est sorti vainqueur de sa comparaison avec l'héparine non fractionnée. Son utilisation nécessite cependant une surveillance attentive. [less ▲]

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See detailL'anticoagulation en hémodialyse
Krzesinski, Jean-Marie ULg; Rorive, Georges ULg

in Néphrologie, Dialyse et Transplantation (1993)

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See detailANTICOAGULATION FOR GERIATRIC PATIENTS WITH ATRIAL FIBRILLATION
DOUPAGNE, G; Petermans, Jean ULg

in NPG. Neurologie - Psychiatrie - Gériatrie (2012), 12

À partir de deux cas cliniques fréquemment rencontrés dans la pratique gériatrique, nous avons revu les indications de prescription d’anticoagulants et leurs applications dans la population gériatrique ... [more ▼]

À partir de deux cas cliniques fréquemment rencontrés dans la pratique gériatrique, nous avons revu les indications de prescription d’anticoagulants et leurs applications dans la population gériatrique. La décision d’instaurer un traitement anticoagulant chez une personne âgée est grave, les conséquences pouvant en effet être importantes. Le risque hémorragique doit être mis en balance avec le risque embolique. L’un comme l’autre peut précipiter la dégradation physique et cognitive et altérer fortement la qualité de vie. De nombreux facteurs doivent être pris en considération. Même si l’utilisation des scores de risque doit être conseillée, l’importance du travail d’équipe, de l’évaluation des fonctions cognitives et de la communication entre les intervenants médicaux et paramédicaux permettent de bien cerner le profil du patient. Le rôle du médecin généraliste est également important dans la surveillance de l’INR, même si l’arrivée des nouveaux anticoagulants ne nécessitant pas de suivi biologique résoudra peut-être une partie du problème de la surveillance thérapeutique. Toutefois, l’utilisation de ce traitement chez les personnes âgées les plus vulnérables nécessitera toujours une grande prudence. L’absence de recommandations claires pour les patients âgés en fibrillation auriculaire nécessite souvent des décisions au cas par cas. [less ▲]

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See detailAnticoherence and entanglement of spin states
Martin, John ULg; Baguette, Dorian ULg; Damanet, François ULg et al

Scientific conference (2016, March 02)

We investigate multiqubit permutation-symmetric states with maxi- mally mixed reduced density matrices in the symmetric subspace [1]. Such states can be viewed as particular spin states, namely anticoher ... [more ▼]

We investigate multiqubit permutation-symmetric states with maxi- mally mixed reduced density matrices in the symmetric subspace [1]. Such states can be viewed as particular spin states, namely anticoher- ent spin states [2]. Using the Majorana representation of spin states in terms of points on the unit sphere [3], we analyze the consequences of degeneracies of the Majorana points and of a point-group symmetry in their arrangement on the existence of anticoherent spin states. We provide different characterizations of anticoherence and establish a link between point symmetries, anticoherence, and SLOCC classes [4]. We consider in detail the case of small numbers of qubits and solve the 4-qubit case completely by identifying and characterizing all 4-qubit anticoherent states. [1] D. Baguette, T. Bastin, and J. Martin, Phys. Rev. A 90, 032314 (2014); O. Giraud et al., Phys. Rev. Lett. 114, 080401 (2015); D. Baguette et al., Phys. Rev. A 92, 052333 (2015). [2] J. Zimba, Electron. J. Theor. Phys. 3, 143 (2006). [3] E. Majorana, Nuovo Cimento 9, 43 (1932). [4] SLOCC classes : Classes of states equivalent through stochastic local operations with classical communication. [less ▲]

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See detailAnticoherence of multiqubit symmetric states
Baguette, Dorian ULg; Bastin, Thierry ULg; Martin, John ULg

Conference (2015, May 13)

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See detailAnticoherence of spin states with point-group symmetries
Baguette, Dorian ULg; Damanet, François ULg; Giraud, Olivier et al

Poster (2016, May 18)

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See detailAnticoherence of spin states with point-group symmetries
Baguette, Dorian ULg; Damanet, François ULg; Giraud, Olivier et al

Poster (2016, March 02)

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana ... [more ▼]

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana represen- tation of spin states in terms of points on the unit sphere, we analyze the consequences of a point-group symmetry in their arrangement on the quantum properties of the corresponding state [1]. We focus on the identi cation of anticoherent states (for which all reduced density matrices in the symmetric subspace are maximally mixed) associated with point-group-symmetric sets of points. We provide three di erent characterizations of anticoherence and establish a link between point symmetries, anticoherence, and classes of states equivalent through stochastic local operations with classical communication. We then in- vestigate in detail the case of small numbers of qubits and construct in nite families of anticoherent states with point-group symmetry of their Majorana points, showing that anticoherent states do exist to arbitrary order. [1] D. Baguette et al., Phys. Rev. A 92, 052333 (2015). [less ▲]

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See detailAnticoherence of spin states with point-group symmetries
Baguette, Dorian ULg; Damanet, François ULg; Giraud, Olivier et al

in Physical Review A (2015), 92

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana ... [more ▼]

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana representation of spin states in terms of points on the unit sphere, we analyze the consequences of a point-group symmetry in their arrangement on the quantum properties of the corresponding state. We focus on the identification of anticoherent states (for which all reduced density matrices in the symmetric subspace are maximally mixed) associated with point-group-symmetric sets of points. We provide three different characterizations of anticoherence and establish a link between point symmetries, anticoherence, and classes of states equivalent through stochastic local operations with classical communication. We then investigate in detail the case of small numbers of qubits and construct infinite families of anticoherent states with point-group symmetry of their Majorana points, showing that anticoherent states do exist to arbitrary order. [less ▲]

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See detailAnticonvulsant properties of 4-cycloalkylamino-pyrid-3-yl sulfonylureas and -thioureas
Masereel, B.; Lambert, D.; Bia, F. et al

in Journal de Pharmacie de Belgique (1996), 51

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See detailAnticonvulsant properties of 4-cycloalkylamino-pyrid-3-yl sulfonylureas and -thioureas
Masereel, B.; Lambert, D.; Bia, F. et al

Poster (1995, June)

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See detailAnticorps anti-gliadines déamidées et maladie coeliaque : données actuelles et évaluation des faux positifs de cinq trousses de dosage
Lutteri, Laurence ULg; Sagot, Laurence; Chapelle, Jean-Paul ULg

in Annales de Biologie Clinique (2010), 68(2), 149-56

Recently, anti-deamidated gliadin antihodies were proposed for the serological diagnosis of celiac disease. We evaluate the specificity of different anti-deamidated gliadin antibodies ELISA in comparison ... [more ▼]

Recently, anti-deamidated gliadin antihodies were proposed for the serological diagnosis of celiac disease. We evaluate the specificity of different anti-deamidated gliadin antibodies ELISA in comparison with conventional anti-native gliadin kits. Serum sainples froin 46 non celiac patients trere analyzed by five different quantitative ELISA for anti-native gliadin, antideamidated gliadin and anti-fransglutaininase neo-epitope antibodies together with a screening ELISA. Twenty-four percent of the patients deinonstrated anti-native gliadin lgA and 63% 1gO antibodies. Using anti-dearnidated gliadin antibodies, tire number of false positive IgA and, particularly, 1gG results,markedly decreased in the non celiac patients: 21 and 24% respectively with anti-Gliadin (GAF-3X) Euroimmun kit, 7 and 26% with Bindazyme 1-lurnan Anti-Gliadin (MGP) The Binding Site kit and 0 and 41% with Celiac G+ Immco kit. The new assay which makes use of the physiological complex of tissue transglutaminase cross-linked with deamidated gliadin peptides, called neo-epitope, did not improve the differential diagnosis of celiac disease with 30% of false positive results in IgG (2% in IgA). IJsing the Inova screening kit, a positive resuit for IgA and/or IgG anti-deamidated gliadin and!or anti- tissue transglutaminase antibodies was obtained in 24% of the non celiac patients. In conclusion, our study assessed the superiority, in ternis of specificity, of anti-deamidated gliadin antibodies, over the conventional anti-gliadin antibodies for die differential diagnosis of celiac disease. [less ▲]

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See detailAnticorps anticytoplasme des polynucléaires neutrophiles (ANCA) dans les maladies inflammatoires du tube digestif
Lamproye, Anne ULg; Belaiche, Jacques ULg; Louis, Edouard ULg et al

in Acta Gastro-Enterologica Belgica (1994), 57(2, Mar-Apr), 171-6

Antineutrophil cytoplasmic antibodies have recently been demonstrated in sera of patients with inflammatory bowel disease. We are reporting here our experience among 94 patients with Crohn's disease and ... [more ▼]

Antineutrophil cytoplasmic antibodies have recently been demonstrated in sera of patients with inflammatory bowel disease. We are reporting here our experience among 94 patients with Crohn's disease and 25 with ulcerative colitis. The indirect immunofluorescence assay with alcohol fixed neutrophils has been used. The presence of antineutrophil cytoplasmic antibodies was significantly associated to the ulcerative colitis 61% VS 17% (p < 0.001). The fluorescence had a perinuclear pattern among all but one suffering from ulcerative colitis. Among the patients suffering from ulcerative colitis there was no relationship between the presence of antineutrophil cytoplasmic antibodies and the activity or the localisation of the disease. Among the 9 patients operated for their ulcerative colitis, 4 were ANCA positive and remained so after proctocolectomy. The existence of antineutrophil cytoplasmic antibodies is useful for the diagnosis of some unclassifiable colitis. Their presence may be used as an argument in favour of some disturbances of the immunoregulation of the disease. [less ▲]

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See detailLes anticorps hétérophiles : une cause souvent méconnue d'erreurs de diagnostic
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Beckers, Albert ULg

in 27ème Congrès de la Société Française d'Endocrinologie - Deauville, 29 septembre - 2 octobre 2010 (2010, September)

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See detailLes anticorps hétérophiles : une cause souvent méconnue d'erreurs de diagnostic
Cavalier, Etienne ULg; Carlisi, A.; Delanaye, Pierre ULg et al

in Annales d'Endocrinologie (2010, September), 71(5), 367-68

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See detailAnticorps monoclonaux a usage therapeutique en hemato-oncologie. Generalites.
Gennigens, Christine ULg; Collignon, Joëlle ULg; Jerusalem, Guy ULg et al

in Revue Médicale de Liège (2009), 64(5-6), 264-7

For many years, chemotherapy, hormonotherapy and immunotherapy were the mainstay of cancer treatment. Recent advances in our knowledge of cell biology and particularly of cancer cell transformation ... [more ▼]

For many years, chemotherapy, hormonotherapy and immunotherapy were the mainstay of cancer treatment. Recent advances in our knowledge of cell biology and particularly of cancer cell transformation, growth and metastasis have led to the identification of specific pathways playing a role in the pathophysiology of cancer. New drugs specifically developed to control these targets are collectively named "targeted therapies". Two types of targeted therapies are available: kinase (mainly tyrosine kinase) inhibitors (suffix -nib) are small molecules binding directly to the intracellular kinase domain and acting as competitive inhibitor of ATP binding and monoclonal antibodies (suffix -mab) directed towards specific cell surface receptors or their ligands to prevent receptor activation. This paper will only review monoclonal antibodies (mabs). Thirty years after their discovery mAbs have become efficient therapeutic tools. Progress in molecular engineering as well as improved knowledge of cell signalling pathways together with a better selection of the targets turned them into valuable treatments. Several mAbs are currently licensed for the treatment of hematological or solid malignancies and many others are expected in the near future. [less ▲]

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See detailAnticorps monoclonaux en cardiologie.
Legrand, Victor ULg

in Revue medicale de Liege (2009), 64(5-6), 310-2

Clinical efficacy of antiplatelet agents administration to reduce ischemic complications has supported the concept of atherothrombosis and plaque rupture. Specifically, administration of monoclonal ... [more ▼]

Clinical efficacy of antiplatelet agents administration to reduce ischemic complications has supported the concept of atherothrombosis and plaque rupture. Specifically, administration of monoclonal antibody against platelet membrane receptor glycoprotein IIb/IIa was shown to be highly effective whenever percutaneous intervention is performed in the setting of unstable coronary syndrome. The in-hospital use of glycoprotein IIb/IIIa is unanimously recommended in these situations. [less ▲]

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