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See detailMale aromatase-knockout mice exhibit normal levels of activity, anxiety and "depressive-like" symptomatology
Dalla, C.; Antoniou, K.; Papadopoulou-Daifoti, Z. et al

in Behavioural Brain Research (2005), 163(2), 186-193

It is well known that estradiol derived from neural aromatization of testosterone plays a crucial role in the development of the male brain and the display of sexual behaviors in adulthood. It was ... [more ▼]

It is well known that estradiol derived from neural aromatization of testosterone plays a crucial role in the development of the male brain and the display of sexual behaviors in adulthood. It was recently found that male aromatase knockout mice (ArKO) deficient in estradiol due to a mutation in the aromatase gene have general deficits in coital behavior and are sexually less motivated. We wondered whether these behavioral deficits of ArKO males could be related to changes in activity, exploration, anxiety and "depressive-like" symptomatology. ArKO and wild type (WT) males were subjected to open field (OF), elevated plus maze (EPM), and forced swim tests (FST), after being exposed or not to chronic mild stress (CMS). CNIS was used to evaluate the impact of chronic stressful procedures and to unveil possible differences between genotypes. There was no effect of genotype on OF, EPM and FST behavioral parameters. WT and ArKO mice exposed to CMS or not exhibited the same behavioral profile during these three types of tests. However, all CMS-exposed mice (ArKO and WT) spent less time in the center of the EPM. Additionally, floating duration measured in the FST increased between two tests in both WT and ArKO mice, though that increase was less prominent in mice previously subjected to CNIS than in controls. Therefore, both ArKO and WT males displayed the same behavior and had the same response to CMS however CMS exposure slightly modified the behavior displayed by mice of both genotypes in the FST and EPM paradigms. These results show that ArKO males display normal levels of activity, exploration, anxiety and "depressive-like" symptomatology and thus their deficits in sexual behavior are specific in nature and do not result indirectly from other behavioral changes. (c) 2005 Published by Elsevier B.V. [less ▲]

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See detailMale hypogonadism caused by insolated LH deficiency : From pathology to gene, from gene to physiology
Valdes Socin, Hernan Gonzalo ULg; Salvi, R.; Pralong, F. et al

in 8th International Pituitary Congress - Abstract book (2003)

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See detailMale hypogonadism caused by insolated LH deficiency : From pathology to gene, from gene to physiology
Valdes Socin, Hernan Gonzalo ULg; Salvi, R.; Pralong, F. et al

in 12th International Congress of Endocrinology - Abstract book (2004)

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See detailMale hypogonadism caused by insolated LH deficiency : From pathology to gene, from gene to physiology
Valdes Socin, Hernan Gonzalo ULg; Salvi, R.; Pralong, F. et al

in The 85th Annual Meeting of the Endocrine Society - Abstract book (2003)

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See detailMale hypogonadism caused by isolated LH deficiency : From pathology to gene, from gene to physiology
Valdes Socin, Hernan Gonzalo ULg; Salvi, R.; Pralong, F. et al

in Meeting of the Belgian Endocrine Society : December 2003 (2003, December)

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See detailMale hypogonadism caused by isolated LH deficiency : From pathology to gene, from gene to physiology
Valdes Socin, Hernan Gonzalo ULg; Salvi, R.; Pralong, F. et al

in ENEA congress : Napoli, April 2004 (2004, April)

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See detailMale Hypogonadism caused by isolated luteinizing hormone deficiency
Daly, Adrian ULg; Salvi, R.; Petrossians, Patrick ULg et al

in 37th International symposium - GH and Growth Factors in Endocrinology and Metabolism (Athènes Symposium) (2005)

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See detailMale-biased genes are overrepresented among novel Drosophila pseudoobscura sex-biased genes.
Metta, Muralidhar ULg; Schlotterer, Christian

in BMC Evolutionary Biology (2008), 8

BACKGROUND: The origin of functional innovation is among the key questions in biology. Recently, it has been shown that new genes could arise from non-coding DNA and that such novel genes are often ... [more ▼]

BACKGROUND: The origin of functional innovation is among the key questions in biology. Recently, it has been shown that new genes could arise from non-coding DNA and that such novel genes are often involved in male reproduction. RESULTS: With the aim of identifying novel genes, we used the technique "generation of longer cDNA fragments from serial analysis of gene expression (SAGE) tags for gene identification (GLGI)" to extend 84 sex-biased 3'end SAGE tags that previously could not be mapped to the D. pseudoobscura transcriptome. Eleven male-biased and 33 female-biased GLGI fragments were obtained, of which 5 male-biased and 3 female-biased tags corresponded to putatively novel genes. This excess of novel genes with a male-biased gene expression pattern is consistent with previous results, which found novel genes to be primarily expressed in male reproductive tissues. 5' RACE analysis indicated that these novel transcripts are very short in length and could contain introns. Interspecies comparisons revealed that most novel transcripts show evidence for purifying selection. CONCLUSION: Overall, our data indicate that among sex-biased genes a considerable number of novel genes (approximately 2-4%) exist in D. pseudoobscura, which could not be predicted based on D. melanogaster gene models. [less ▲]

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See detailMaledictio adversus ecclesiaeDei persequtores. A propos d'un ouvrage récent
George, Philippe ULg

in Revue Belge de Philologie et d'Histoire (1995), LXXIII

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See detailLa malédiction de Cassandre. Histoire d'une plateforme distribuée d'analyse qualitative de textes et d'images
Lejeune, Christophe ULg

Scientific conference (2014, February 07)

Le logciel Cassandre fait partie de la plateforme Hypertopic d'annotation collaborative de textes et d'images. Du point de vue de la recherche en informatique, le développement de cette plateforme s ... [more ▼]

Le logciel Cassandre fait partie de la plateforme Hypertopic d'annotation collaborative de textes et d'images. Du point de vue de la recherche en informatique, le développement de cette plateforme s'insère dans le courant du Web socio-sémantique. Du point de vue des sciences humaines, la plateforme fournit des outils de recherche qualitative. Christophe Lejeune fait le récit de son expérience de développement (de 2005 à aujourd'hui). Ce faisant, il illustre des notions abordées dans les séances précédentes, telles que les questions de gestionnaire de versions, les services Web RESTful, les centres de calcul, les nuages, les collaborations inter-universitaires, les communautés Open Source et la relation avec les utilisateurs. [less ▲]

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See detailLe malentendu comme structure de la communication
Servais, Christine ULg; Servais, Véronique ULg

in Questions de Communication (2009), 15

Dans les modèles télégraphiques,on considère que la communication fonctionne si les messages de départ et d’arrivée sont identiques.Sinon, cela signifie que le récepteur a mal compris ou que l’émetteur ... [more ▼]

Dans les modèles télégraphiques,on considère que la communication fonctionne si les messages de départ et d’arrivée sont identiques.Sinon, cela signifie que le récepteur a mal compris ou que l’émetteur s’est mal fait comprendre. Dans ce cadre, la pathologie de la communication est l’incompréhension. Ce que nous proposons ici, à partir de l’analyse de situations de communication très particulières (des rencontres enchantées avec des dauphins sauvages), c’est que, à l’inverse, la structure fondamentale de la communication est le malentendu. Or, c’est le refus de reconnaître ce fait (dû notamment au désir vain et désastreux de contrôler le partenaire) qui engendre des pathologies.Admettre au contraire qu’émetteur et récepteur disposent nécessairement de versions différentes de l’interaction et qu’il n’y a pas de version plus objective qu’une autre, c’est replacer l’altérité au coeur d’une communication qui est réussie parce qu’on accepte de mal se comprendre. [less ▲]

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See detailMalentendus sur les apports du conditionnement
Richelle, Marc ULg

in Revue de Comportement Animal (1970), 4

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See detailLa malformation de Chiari I chez l'adulte: évolution récente de la prise en charge
Noudel, R; Bazin, A; Litré, Claude Fabien ULg et al

Conference (2003, June)

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See detailLes malformations arterio-veineuses congénitales des membres: à propos de 4 cas
Krawczykowski, D.; VAN DAMME, Hendrik ULg; TROTTEUR, Geneviève ULg et al

in Revue Médicale de Liège (1992), 47(6), 284-91

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See detailLes malformations congénitales dans un service de néonatologie.
Battisti, Oreste ULg; Bachy, A.; Gérard, P.

Conference (1983, November 21)

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See detailLes malformations congénitales dans un service de néonatologie.
Battisti, Oreste ULg; Gillerot, Y.; Bachy, A. et al

in Louvain Medical (1985), 104

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See detailMalformations vasculaires du système nerveux central : que faire quand on en trouve ?
SCHOLTES, Félix ULg; MARTIN, Didier ULg

Scientific conference (2013, January 16)

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See detail« Malheur et vanités » [traduction d’un texte latin de Bohuslav Hasištejnský de Lobkovic]
Pietquin, Paul ULg; Lhoest, Fr.

in Polet, Jean-Claude (Ed.) Patrimoine littéraire européen. 6 : Prémices de l'humanisme : 1400-1515 (1995)

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