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See detailMcLuhan, trente ans après
Durand, Pascal ULg

in Quaderni : la Revue de la Communication (1999), 37

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See detailMcLuhan, trente ans après
Durand, Pascal ULg

in Quaderni : la Revue de la Communication (1999), 37

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See detailMDRD equation for GFR estimation : analytical limitations
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Krzesinski, Jean-Marie ULg et al

Conference (2007, March 23)

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See detailMDRD or CKD-EPI study equations for estimating prevalence of stage 3 CKD in epidemiological studies: which difference? Is this difference relevant?
Delanaye, Pierre ULg; Cavalier, Etienne ULg; Mariat, C. et al

in BMC Nephrology (2010), 11(8),

Background: Prevalence of stage 3 chronic kidney disease (CKD) is increasing according to the NHANES study. Prevalence has been calculated using the MDRD study equation for estimating glomerular ... [more ▼]

Background: Prevalence of stage 3 chronic kidney disease (CKD) is increasing according to the NHANES study. Prevalence has been calculated using the MDRD study equation for estimating glomerular filtration rate (GFR). Recently, a new estimator based on creatinine, the CKD-EPI equation, has been proposed which is presumed to better perform in normal GFR ranges. The aim of the study was to measure the difference in prevalence of stage 3 CKD in a population using either the MDRD or the CKD-EPI study equations. Methods: CKDscreening is organized in the Province of Liège, Belgium. On a voluntary basis, people aged between 45 and 75 years are invited to be screened. GFR is estimated by the MDRD study equation and by the "new" CKD-EPI equations. Results: The population screened consisted in 1992 people (47% of men). Mean serum creatinine was 0.86 ± 0.20 mg/dl. The prevalence of stage 3 CKD in this population using the MDRD or the CKD-EPI equations was 11.04 and 7.98%, respectively. The prevalence of stage 3 CKD is significantly higher with the MDRD study equation (p <0,0012). Conclusions: Prevalence of stage 3 CKDvaries strongly following the method used for estimating GFR, MDRD or CKDEPI study equations. Such discrepancies are of importance and must be confirmed and explained by additional studies using GFR measured with a reference method. [less ▲]

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See detailMDRD versus CKD-EPI equation to estimate glomerular filtration rate in kidney transplant recipients
Masson, Ingrid; Flamant, Martin; Maillard, Nicolas et al

in Transplantation (2013), 95(10), 1211-1217

Background. The new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine-based equation was developed to address the systematic underestimation of the glomerular filtration rate (GFR) by ... [more ▼]

Background. The new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine-based equation was developed to address the systematic underestimation of the glomerular filtration rate (GFR) by the Modification of Diet in Renal Disease (MDRD) Study equation in patients with a relatively well-preserved kidney function. The performance of the new equation for kidney transplant recipients is discussed. Methods. We analyzed the performances of the CKD-EPI equation in comparison with the MDRD Study equation in 825 stable kidney transplant recipients. Bias, precision, and accuracy within 30% of true GFR were determined. GFR was measured by urinary clearance of inulin (n=488) and plasma clearance of 51Cr-EDTA (n=337). Results. Mean measured GFR (mGFR) was 50T19 mL/min/1.73 m2. On the whole cohort, bias was significantly lower for MDRD Study equation compared with CKD-EPI creatinine. This superiority translates into a better accuracy (80% and 74% for the MDRD and CKD-EPI creatinine, respectively). The best performance of the MDRD Study equation is confirmed both in the subgroups of patients with mGFR G60 mL/min/1.73 m2 and between 60 and 90 mL/min/1.73 m2. For mGFR 990 mL/min/1.73 m2, there were no significant differences between the two equations in terms of performance. Conclusions. The CKD-EPI creatinine equation does not offer a better GFR prediction in renal transplant patients compared with the MDRD Study equation, even in the earlier CKD stages. [less ▲]

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See detailMDRD VERSUS CKD-EPI EQUATIONS TO ESTIMATE GLOMERULAR FILTRATION RATE IN OBESE PATIENTS
BOUQUEGNEAU, Antoine ULg; CAVALIER, Etienne ULg; Krzesinski, Jean-Marie ULg et al

in Nephrology Dialysis Transplantation (2013, April 18), 28(supplément 1), 117-139

Introduction and Aims: Obesity is recognized as a risk factor both for the development and progression of chronic kidney disease (CKD). Estimating glomerular filtration rate (GFR) is thus especially ... [more ▼]

Introduction and Aims: Obesity is recognized as a risk factor both for the development and progression of chronic kidney disease (CKD). Estimating glomerular filtration rate (GFR) is thus especially important to follow these patients. We have tested the performances of two creatinine-based equations, namely the MDRD and CKD-EPI equations, in an obese population. Conclusions :Both in the global and subgroup analyses, the CKD-EPI equation did not outperform the MDRD study equation. The performances of both equations were worse in CKD patients. These two conclusions were still valid if indexed GFR was considered. [less ▲]

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See detailMDRD Versus CKD_EPI equation to estimate glomerular filtration rate in kidney transplant recipients
masson, Ingrid; Flamant, Martin; Maillard, Nicolas et al

in Transplantation (2013), 95(10),

Background. The new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine-based equation was developed to address the systematic underestimation of the glomerular filtration rate (GFR) by ... [more ▼]

Background. The new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine-based equation was developed to address the systematic underestimation of the glomerular filtration rate (GFR) by the Modification of Diet in Renal Disease (MDRD) Study equation in patients with a relatively well-preserved kidney function. The performance of the new equation for kidney transplant recipients is discussed. Methods. We analyzed the performances of the CKD-EPI equation in comparison with the MDRD Study equation in 825 stable kidney transplant recipients. Bias, precision, and accuracy within 30% of true GFR were determined. GFR was measured by urinary clearance of inulin (n=488) and plasma clearance of 51Cr-EDTA (n=337). Results. Mean measured GFR (mGFR) was 50T19 mL/min/1.73 m2. On the whole cohort, bias was significantly lower for MDRD Study equation compared with CKD-EPI creatinine. This superiority translates into a better accuracy (80% and 74% for the MDRD and CKD-EPI creatinine, respectively). The best performance of the MDRD Study equation is confirmed both in the subgroups of patients with mGFR G60 mL/min/1.73 m2 and between 60 and 90 mL/min/1.73 m2. For mGFR 990 mL/min/1.73 m2, there were no significant differences between the two equations in terms of performance. Conclusions. The CKD-EPI creatinine equation does not offer a better GFR prediction in renal transplant patients compared with the MDRD Study equation, even in the earlier CKD stages. [less ▲]

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See detailMe, Myself and I
Dejasse, Erwin ULg

in Anny Servais (2004)

L'autoportrait dans la peinture d'Anny Servais

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See detailMealworms: Alternate Source of Lipids
Danthine, Sabine ULg; Blecker, Christophe ULg; Paul, Aman ULg et al

Scientific conference (2014, May 16)

The aim of present study was to determine the physicochemical properties of the oil obtained from Tenebrio molitor larvae (mealworms) and explore its potential as edible oil. Five batches of Tenebrio ... [more ▼]

The aim of present study was to determine the physicochemical properties of the oil obtained from Tenebrio molitor larvae (mealworms) and explore its potential as edible oil. Five batches of Tenebrio molitor larvae were investigated for their lipid content and physiochemical properties. Three batches were reared in lab (3 different productions) and two were purchased from a local supplier. The lipids were extracted using a cold extraction technique employing 2:1 ratio chloroform/methanol as solvent. The fatty acid profile was determined using gas chromatography and triacylglycerol profile using HPLC. The thermal properties of the lipid extracts were also analyzed using differential scanning calorimetry. All the samples contained high amount of unsaturated fatty acids. The chemical composition and the thermal properties of the samples varied with the source. With this quantity and quality of lipid content, mealworms offer potential as an important source of edible lipids. [less ▲]

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See detailMean Expression of the X-Chromosome is Associated with Neuronal Density.
Swingland, James T.; Durrenberger, Pascal F.; Reynolds, Richard et al

in Frontiers in Neuroscience (2012), 6

Background: Neurodegenerative diseases are characterized by key features such as loss of neurons, astrocytosis, and microglial activation/proliferation. These changes cause differences in the density of ... [more ▼]

Background: Neurodegenerative diseases are characterized by key features such as loss of neurons, astrocytosis, and microglial activation/proliferation. These changes cause differences in the density of cell types between control and disease subjects, confounding results from gene expression studies. Chromosome X (ChrX) is known to be specifically important in the brain. We hypothesized the existence of a chromosomal signature of gene expression associated with the X-chromosome for neurological conditions not normally associated with that chromosome. The hypothesis was investigated using publicly available microarray datasets from studies on Parkinson's disease, Alzheimer's disease, and Huntington's disease. Data were analyzed using Chromowave, an analytical tool for detecting spatially extended expression changes along chromosomes. To examine associations with neuronal density and astrocytosis, the expression of cell specific reporter genes was extracted. The association between these genes and the expression patterns extracted by Chromowave was then analyzed. Further analyses of the X:Autosome ratios for laser dissected neurons, microglia cultures and whole tissue were performed to detect cell specific differences. Results: We observed an extended pattern of low expression of ChrX consistent in all the neurodegenerative disease brain datasets. There was a strong correlation between mean ChrX expression and the pattern extracted from the autosomal genes representing neurons, but not with mean autosomal expression. No chromosomal patterns associated with the neuron specific genes were found on other chromosomes. The chromosomal expression pattern was not present in datasets from blood cells. The X:Autosome expression ratio was also higher in neuronal cells than in tissues with a mix of cell types. Conclusions: The results suggest that neurological disorders show as a reduction in mean expression of many genes along ChrX. The most likely explanation for this finding relates to the documented general up-regulation of ChrX in brain tissue which, this work suggests, occurs primarily in neurons. If validated, this cell specific ChrX expression warrants further research as understanding the biological reasons and mechanisms for this expression, may help to elucidate a connection with the development of neurodegenerative disorders. [less ▲]

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See detailThe mean features and characteristics of the 3D FEM in the central area of Shanghai
Dassargues, Alain ULg; Biver, Pierre

in Proceedings of the Int. Conf. on Modelling Groundwater flow and pollution, Nanjing (1991)

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See detailMean Fluxes Across Sections in the Mediterranean Sea Derived from GCM results
Stanev, E.; Beckers, Jean-Marie ULg

in Journal of Marine Systems (1991), 1

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See detailMean length of utterance of children with Down syndrome
Rondal, Jean-Adolphe ULg; Ghiotto, M.; Brédart, Serge ULg et al

in American Journal on Mental Retardation (1988), 93(1), 64-66

Mean length of utterance (MLU) of children with Down syndrome was examined and found to correlate highly with chronological age, r = .87, p less than .001, despite the children's language delays. The ... [more ▼]

Mean length of utterance (MLU) of children with Down syndrome was examined and found to correlate highly with chronological age, r = .87, p less than .001, despite the children's language delays. The correlation was reliable at least up to MLU 3.00. In the 1.00 to 3.50 range, MLU also predicted grammatical complexity. [less ▲]

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See detailThe mean magnetic field modulus of AP stars
Mathys, G.; Hubrig, S.; Landstreet, J. D. et al

in Astronomy and Astrophysics. Supplement Series (1997), 123

We present new measurements of the mean magnetic field modulus of a sample of Ap stars with spectral lines resolved into magnetically split components. We report the discovery of 16 new stars having this ... [more ▼]

We present new measurements of the mean magnetic field modulus of a sample of Ap stars with spectral lines resolved into magnetically split components. We report the discovery of 16 new stars having this property. This brings the total number of such stars known to 42. We have performed more than 750 measurements of the mean field modulus of 40 of these 42 stars, between May 1988 and August 1995. The best of them have an estimated accuracy of 25 - 30 G. The availability of such a large number of measurements allows us to discuss for the first time the distribution of the field modulus intensities. A most intriguing result is the apparent existence of a sharp cutoff at the low end of this distribution, since no star with a field modulus (averaged over the rotation period) smaller than 2.8 kG has been found in this study. For more than one third of the studied stars, enough field determinations well distributed throughout the stellar rotation cycle have been achieved to allow us to characterize at least to some extent the variations of the field modulus. These variations are often significantly anharmonic, and it is not unusual for their extrema not to coincide in phase with the extrema of the longitudinal field (for the few stars for which enough data exist about the latter). This, together with considerations on the distribution of the relative amplitude of variation of the studied stars, supports the recently emerging evidence for markedly non-dipolar geometry and fine structure of the magnetic fields of most Ap stars. New or improved determinations of the rotation periods of 9 Ap stars have been achieved from the analysis of the variations of their mean magnetic field modulus. Tentative values of the period have been derived for 5 additional stars, and lower limits have been established for 10 stars. The shortest definite rotation period of an Ap star with magnetically resolved lines is 3.4 deg, while those stars that rotate slowest appear to have periods in excess of 70 or 75 years. As a result of this study, the number of known Ap stars with rotation periods longer than 30 days is almost doubled. We briefly rediscuss the slow-rotation tail of the period distribution of Ap stars. This study also yielded the discovery of radial velocity variations in 8 stars. There seems to be a deficiency of binaries with short orbital periods among Ap stars with magnetically resolved lines. Based on observations collected at the European Southern Observatory (La Silla, Chile; ESO programmes Nos. 43.7-004, 44.7-012, 49.7-030, 50.7-067, 51.7-041, 52.7-063, 53.7-028, 54.E-0416, and 55.E-0751), at the Observatoire de Haute-Provence (Saint-Michel-l'Observatoire, France), at Kitt Peak National Observatory, and at the Canada-France-Hawaii Telescope. Tables 2, 3, and 4 are also available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/Abstract.html. [less ▲]

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See detailMean-Variance versus Mean-VaR and Mean-Utility Spanning
Bodson, Laurent ULg; Hübner, Georges ULg

in Gregoriou, Greg N. (Ed.) Stock Market Volatility Book (2008)

In this chapter, we contrast the optimal spanning properties of portfolios built under the traditional mean-variance (VAR) or mean-modified value-at-risk (MVaR) approaches with those created with the ... [more ▼]

In this chapter, we contrast the optimal spanning properties of portfolios built under the traditional mean-variance (VAR) or mean-modified value-at-risk (MVaR) approaches with those created with the linear-exponential (linex) utility function. Unlike asset allocation procedures that build on volatility or MVaR as a measure of risk and a single risk aversion parameter that characterizes investors, the use of linex utility introduces risk differentiation amongst investors and the risk-return relation of the optimal portfolio trades off between mean, variance, skewness and kurtosis. We identify efficient portfolios under the three competing frameworks and analyze their optimal allocations. [less ▲]

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See detailMean-Variance versus Mean-VaR and Mean-Utility Spanning
Bodson, Laurent ULg; Hübner, Georges ULg

in Gregoriou, Greg (Ed.) Stock Market Volatility (2009)

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See detailMeandering flows in rectangular shallow reservoirs
Peltier, Yann ULg; Erpicum, Sébastien ULg; Dewals, Benjamin ULg

Report (2014)

During this research, previously unexplored meandering flows in free-surface rectangular shallow reservoirs were investigated theoretically, experimentally and numerically. For the first time, a complete ... [more ▼]

During this research, previously unexplored meandering flows in free-surface rectangular shallow reservoirs were investigated theoretically, experimentally and numerically. For the first time, a complete description of the hydrodynamics of the meandering flows was obtained from laboratory experiments. An innovative procedure for the characterisation of the physics of the flow was developed based on several techniques, including Large Scale Particle Image Velocimetry (LSPIV), Proper Orthogonal Decomposition (POD) and a new topology algorithm. This research provides new insights into these fascinating meandering flows, of high practical relevance in civil and environmental engineering. Six papers were written and, so far, five of them have been accepted for publication (two in international journals and three in peer-reviewed international conference proceedings). [less ▲]

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See detailMeandering jets in shallow rectangular reservoir
Peltier, Yann ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in 7th International Conference in River Hydraulics, River Flow 2014 (2014)

In this article, meandering flows in a shallow rectangular reservoir are experimentally and numerically investigated. Two experiments were performed in a smooth shallow horizontal flume and the surface ... [more ▼]

In this article, meandering flows in a shallow rectangular reservoir are experimentally and numerically investigated. Two experiments were performed in a smooth shallow horizontal flume and the surface velocity fields were measured by Large-Scale PIV (LSPIV). The flow conditions were chosen in such a way that the friction regime of both flows was different. These flows were then modelled using the academic code WOLF2D, which solves the 2D shallow water equations and uses a depth-averaged k- model for modelling turbulence. The main characteristics of the measured and simulated flows were finally extracted from a Proper Orthogonal Decomposition (POD) of the surface velocity fields and depth-averaged velocity fields respectively and were compared. When the mean fluctuating kinetic energy of the considered POD mode is greater than 1×10-5 m²/s², the numerical modelling and the experiments are in good agreement whatever the friction regime of the flow. [less ▲]

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See detailMeandering jets in shallow rectangular reservoirs: POD analysis and identification of coherent structures
Peltier, Yann ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Experiments in Fluids (2014), 55

The effect of the shallowness on meandering jets in a shallow rectangular reservoir is investigated. Four meandering flows were investigated in an experimental shallow rectangular reservoir. Their ... [more ▼]

The effect of the shallowness on meandering jets in a shallow rectangular reservoir is investigated. Four meandering flows were investigated in an experimental shallow rectangular reservoir. Their boundary conditions were chosen to cover a large range of friction numbers (defined with the sudden expansion width). Due to the unsteady characteristics of the flows, a Proper Orthogonal Decomposition of the fluctu-ating part of the surface velocity fields measured using LSPIV was used for discriminating the flow struc-tures responsible for the meandering of the jet. Less than 1 % of the calculated POD modes significantly contribute to the meandering of the jet and two types of instability are in competition in such a flow con-figuration. The sinuous mode is the dominant mode in the flow and it induces the meandering of the flow, while the varicose mode is a source of local mixing and weakly participates to the flow. The fluctuating velocity fields were then reconstructed using the POD modes corresponding to 80% of the total mean fluctuating kinetic energy and the coherent structures were identified using the residual vorticity, their centres being localised using a topology algorithm. The trajectories of the structures centres emphasize that at high friction number the coherent structures are small and laterally paired in the near, middle and far fields of the jet, while with decreasing friction number the structures merge into large horizontal vortices in the far-field of the jet, their trajectories showing more variability in space and time. The analysis of the stability regime finally reveals that the sinuous mode is convectively unstable and may become absolutely unstable at the end of the reservoir when the friction number is small. [less ▲]

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