Individualized cognitive stimulation in AD: Ecological approach based on patient’s expertise activities or interest centre (Symposium on "Cognitive training in elders")
Conference (2013, October 02)Detailed reference viewed: 17 (0 ULg)
Individualized Nutrition of preterm: What are the challenges?
in SENTERRE, Thibault (Ed.) Symposium on Intrauterine and Early Postnatal Nutrition: Long-Term Outcome (2015)Detailed reference viewed: 20 (1 ULg)
Individualized versus standardized exercise training for claudicant patients.
Magne, Julien ; ; et al
Conference (2003)Detailed reference viewed: 18 (1 ULg)
Individualizing treatment of type 2 diabetes by targeting postprandial or fasting hyperglycaemia: Response to a basal vs a premixed insulin regimen by HbA quartiles and ethnicity.
Scheen, André ; ; et al
in Diabetes & metabolism (2015), 41(3), 216-222
AIM: This study evaluated the proportions of prandial (PHG) vs fasting hyperglycaemia (FHG) over 24h in a group of patients with type 2 diabetes (overall and for Caucasian vs Asian patients), and tested ... [more ▼]
AIM: This study evaluated the proportions of prandial (PHG) vs fasting hyperglycaemia (FHG) over 24h in a group of patients with type 2 diabetes (overall and for Caucasian vs Asian patients), and tested the hypothesis that an insulin regimen with a prandial component allows a greater response than basal insulin at low glycated haemoglobin (HbA1c) levels with a higher proportion of PHG than FHG. METHODS: Relative contributions of PHG and FHG to overall hyperglycaemia were analyzed by baseline HbA1c quartiles and by ethnicity at baseline and after 24-week treatment with either insulin glargine or insulin lispro mix 25 in the DURABLE study. RESULTS: With increasing baseline HbA1c, the mean relative contribution of PHG to the total area under the curve decreased (from 41% to 27%) while FHG was increased (from 59% to 73%). Both insulins decreased FHG, but only insulin lispro mix 25 decreased PHG. More patients with baseline HbA1c<9%, where PHG was more relevant, achieved the target HbA1c of<7% at endpoint with insulin lispro mix 25 compared with glargine. On average, Asians had a 10% larger contribution of PHG at all HbA1c quartiles, and a lower proportion of Asians reached the HbA1c target of<7% with either insulin treatment compared with Caucasians. CONCLUSION: At baseline, the contribution of FHG to overall hyperglycaemia predominated at all HbA1c quartiles, whereas PHG was more clinically relevant at lower HbA1c levels and with a greater response to insulin lispro mix 25. Asians had a greater proportion of PHG and a lesser response to either insulins compared with Caucasians. Thus, responses to diabetes drugs by baseline HbA1c and ethnicity are worth investigating to better target and individualize treatment. [less ▲]Detailed reference viewed: 25 (0 ULg)
Individuelles religiöses Erleben auf dem Hintergrund stoischer Vorgaben? Aspekte von Epiktets Gottesbild
in Hermes (2004), 132(4), 495-510Detailed reference viewed: 15 (2 ULg)
in Journal Asiatique (2003), 291
In sanskrit, aruna- means "red, pink". In Avestan, occidental scholars translate auruna by "wild". Nothing explains this paradox between two words whose etymological equivalence is obvious. A precise ... [more ▼]
In sanskrit, aruna- means "red, pink". In Avestan, occidental scholars translate auruna by "wild". Nothing explains this paradox between two words whose etymological equivalence is obvious. A precise reading of the Rig-Vedic stanzas shows that the feminine form of this adjective always qualifies the Dawn. This systematic use modified the meaning of the adjective. Beyond its chromatic value, it indicates in the Rigvedic poetries the intermediate time linking day and night. [less ▲]Detailed reference viewed: 21 (2 ULg)
Indo-iranien *nivaidaia: le mécanisme de l'annonce liturgique
in Estudios Iranios y Turanios (2015), 2Detailed reference viewed: 20 (0 ULg)
Indo-Trinidadian Women and the Indian Public Sphere: Women under the Influence?
Conference (2016, January 06)Detailed reference viewed: 21 (2 ULg)
Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.
; ; et al
in Bioorganic & Medicinal Chemistry (2011), 19(4), 1550-61
Indoleamine 2,3-dioxygenase (IDO) is a heme dioxygenase which has been shown to be involved in the pathological immune escape of diseases such as cancer. The synthesis and structure-activity relationships ... [more ▼]
Indoleamine 2,3-dioxygenase (IDO) is a heme dioxygenase which has been shown to be involved in the pathological immune escape of diseases such as cancer. The synthesis and structure-activity relationships (SAR) of a novel series of IDO inhibitors based on the indol-2-yl ethanone scaffold is described. In vitro and in vivo biological activities have been evaluated, leading to compounds with IC(50) values in the micromolar range in both tests. Introduction of small substituents in the 5- and 6-positions of the indole ring, indole N-methylation and variations of the aromatic side chain are all well tolerated. An iron coordinating group on the linker is a prerequisite for biological activity, thus corroborating the virtual screening results. [less ▲]Detailed reference viewed: 74 (7 ULg)
Indole alkaloids from Strychnos species and their antiplasmodial and cytotoxic activities
Frederich, Michel ; Tits, Monique ; Angenot, Luc
in Chemistry of Natural Compounds (2003), 39(6, NOV-DEC), 513-519
Strychnos species (Loganiaceae) have been studied in the laboratory of Pharmacognosy of the University of Liege for more than fifty years. Although investigations into the Strychnos genus have been going ... [more ▼]
Strychnos species (Loganiaceae) have been studied in the laboratory of Pharmacognosy of the University of Liege for more than fifty years. Although investigations into the Strychnos genus have been going on for a long time in the case of Asian tetanizing and American curarizing species, the first chemical and pharmacological screening on African species was undertaken in the early nineteen fifties by the late Prof A. Denoel (University of Liege, Belgium), who examined twenty-five species of Strychnos collected in the Belgian Congo . This research programme was also an offshoot of an inventory of medicinal and toxic plants in Rwanda, carried out during the years 1969-1970. The Belgian scientists were lucky to observe the tribe of Banyambo, living along the Akagera river on the border between Rwanda and Tanzania, where hunters prepared in front of them an arrow poison with Strychnos usambarensis roots and leaves as the main ingredients . Strychnos species have several ethnobotanical uses. A few species are well known for their incorporation into arrow and ordeal poisons, but play more a role in ethnomedicine against fever, rheumatism, worms, ulcers, leprosy, snake-bites, and so forth . In fact, among about one hundred and ninety species, only six would contain strychnine (1) (Strychnos nux-vomica L. [4-7], S. ignatii P. Bergius [8, 9], and S. wallichiana Steud ex DC. [7, 10] from Asia, S. lucida R. Br. [7, 11] from Australia, S. icaja Baillon [1, 12] from Africa, and S. panamensis [13-15] from South America). Strychnos alkaloids are in fact an example of molecular and pharmacological biodiversity. More than 300 different Strychnos alkaloids have been isolated to date and theypresent various biological activities in several fields: parasitology (amoebiasis, paludism, etc.) [ 16-18], cancer [ 19-22], neurology (tetanizing or curarizing effects) [14, 23, 24-26], inflammation , and so on. [less ▲]Detailed reference viewed: 71 (10 ULg)
Indoleamine 2,3 dioxygenase gene polymorphisms correlate with CD8+ Treg impairment in systemic sclerosis.
in Human Immunology (2013), 74(2), 166-9
Systemic sclerosis (SSc) is characterized by tissue fibrosis, vasculopathy and autoimmunity. Indoleamine 2,3 dioxygenase (IDO) plays a pivotal role in immunological tolerance modulating regulatory T cell ... [more ▼]
Systemic sclerosis (SSc) is characterized by tissue fibrosis, vasculopathy and autoimmunity. Indoleamine 2,3 dioxygenase (IDO) plays a pivotal role in immunological tolerance modulating regulatory T cell (Treg) generation and function. Single nucleotide polymorphisms (SNPs) of IDO gene could impact on Treg function and predispose to autoimmunity. Here, the existence of an association between specific IDO SNPs and SSc was analyzed. Five specific SNPs in IDO gene were searched in 31 SSc patients and 37 healthy controls by gene sequencing or restriction fragment length polymorphism. The function of both CD4+CD25+ and CD8+ Treg from SSc patients was analyzed by proliferation suppression assay. SNP rs7820268 was statistically more frequent in SSc patients than in controls. Notably, SSc patients bearing the T allelic variant of the rs7820268 SNP showed impaired CD8+ Treg function. Our unprecedented data show that a specific IDO gene SNP is associated with an autoimmune disease such as SSc. [less ▲]Detailed reference viewed: 6 (0 ULg)
Indolic compounds degradation pathway in pig manure.
; ; et al
Poster (1994, July)Detailed reference viewed: 8 (0 ULg)
An indolinic cryptoalkaloid from Strychnos mattogrossensis
Angenot, Luc ; ; et al
in Phytochemistry (1990), 29(8), 2746-2749
A new indolinic cryptoalkaloid, mattogrossine, has een isolated from the roots and branches of Strychnos mattogrossensis collected near Manaus. Elucidation of its structure is based mainly on 2D NMR ... [more ▼]
A new indolinic cryptoalkaloid, mattogrossine, has een isolated from the roots and branches of Strychnos mattogrossensis collected near Manaus. Elucidation of its structure is based mainly on 2D NMR studies. Two other indolinic alkaloids were also obtained: strychnobrasiline and 12-hydroxy-11-methoxystrychnobrasiline, and their 13C NMR data are provided [less ▲]Detailed reference viewed: 14 (0 ULg)
Indolomonoterpenic alkaloids from Strychnos icaja roots
Philippe, Geneviève ; De Mol, Patrick ; et al
in Phytochemistry (2003), 62(4), 623-629
In the course of our search for new antiplasmodial alkaloids from Strychnos icaja, we have isolated five alkaloids: three monomers, protostrychnine and genostrychnine, previously described in Strychnos ... [more ▼]
In the course of our search for new antiplasmodial alkaloids from Strychnos icaja, we have isolated five alkaloids: three monomers, protostrychnine and genostrychnine, previously described in Strychnos nux-vomica, pseudostrychnine, already found in the leaves of the plant, a new bisindolic alkaloid, named strychnogucine C, and the first naturally occurring trimeric indolomonoterpenic alkaloid: strychnohexamine. This latter trimeric alkaloid presented an antiplasmodial activity against the FCA Plasmodium falciparum line near I muM. (C) 2002 Elsevier Science Ltd. All rights reserved. [less ▲]Detailed reference viewed: 42 (5 ULg)
Indomethacin-responsive hemicrania associated with an extracranial vascular malformation: report of two cases
; ; et al
in Cephalalgia : An International Journal of Headache (2004), 24(11), 997-1000Detailed reference viewed: 14 (0 ULg)
Indoor Joinery and Furniture Made for Eighteenth-Century Houses in Liège (Belgium)
in Sosnowska, Philippe; Charruadas, Paulo; Fraiture, Pascale (Eds.) et al From Carpentry to joinery : floors and ceilings, shutters and frames, doors and panelling in medieval and modern architecture (2016)
Though few eighteenth-century houses in Liège have conserved their original wooden furniture or fittings, archival research reveals that these elements constituted a key aspect of the domestic interior ... [more ▼]
Though few eighteenth-century houses in Liège have conserved their original wooden furniture or fittings, archival research reveals that these elements constituted a key aspect of the domestic interior. The present work draws largely on a series of public announcements known as Rendages proclamatoires which concerned property belonging to orphans sold by public auction, that exist. From 1697 to 1765, these sources provided descriptions of 257 houses situated within the city walls. The wooden furniture and fittings of eighteenth-century Liegerian houses can clearly be seen to be pertain to far more than the sole history of joinery: they also tell the story of Liege’s domestic living spaces in terms of social structure and cultural change. As such they eloquently illustrate the fact that it is only by taking into account the Old Regime’s conception of architecture as a total entity that we can today work towards establishing an increasingly just, coherent and complete understanding of ancient edifices. [less ▲]Detailed reference viewed: 40 (1 ULg)
The Indotriradites dolianitii Morphon, a distinctive group of miospore species from the Lower Carboniferous of Gondwana.
; ; et al
in Review of Palaeobotany and Palynology (1999), 107Detailed reference viewed: 15 (1 ULg)
Inducción de anticuerpos neutralizantes en cobayos inmunizados con la glicoproteína gp53 del virus de la diarrea viral bovina expresada en plantas transgénicas de alfalfa
; ; et al
Poster (2002, October 20)Detailed reference viewed: 13 (0 ULg)