Pancreatic failure in relation to trauma and sepsis in intensive care patients

in Applied Cardiopulmonary Pathophysiology [=ACP] (1991), 4

Pancreatic injury in equine acute abdomen evaluated by plasma trypsin activity and histopathology of pancreatic tissue

in Veterinary Pathology (2003), 40(1), 8-13

In cases of equine acute abdominal disease, where pancreatic damage is suspected, pancreatic damage can be assessed by measuring increased trypsin activity in the plasma of horses suffering intestinal ... [more ▼]

In cases of equine acute abdominal disease, where pancreatic damage is suspected, pancreatic damage can be assessed by measuring increased trypsin activity in the plasma of horses suffering intestinal obstruction and severe shock. The pancreas is particularly vulnerable to splanchnic hypoperfusion because it is a highly active tissue. In this study, 10 horses undergoing abdominal surgery for intestinal obstruction were assayed for trypsin activity on admission and, because of extensive intestinal lesions that were not amenable to surgery, euthanasia was selected; the pancreas was removed before euthanasia. Trypsin activity in the plasma of these horses was significantly higher than in healthy horses (196 ng/ml +/- 128.2 versus 28.5 ng/ml +/- 19.2; P = 0.0026). Light and transmission electron microscopy revealed slight to severe lesions of vacuolar degeneration, a few zymogen granules, dilation of the endoplasmic reticulum, and swelling of mitochondria in the exocrine pancreas. The activation of an inflammatory cascade occurring during strangulating intestinal obstruction could increase pancreatic anoxic lesions caused by severe shock and hypoperfusion in the horse. Further studies will show the significance of pancreatic lesions and the ensuing damage in equine acute intestinal obstruction and shock. [less ▲]

Pancytopénie néonatale : nouveau syndrome hémorragique chez le bovin

in Point Vétérinaire (2010), 41(Numéro spécial), 79-86

For 30 years, many haemorrhagic syndromes were observed in cattle. The recent observation in Europe of a new entity hemorrhagic highlights a consistent set of clinical cases in calves of all breeds under ... [more ▼]

For 30 years, many haemorrhagic syndromes were observed in cattle. The recent observation in Europe of a new entity hemorrhagic highlights a consistent set of clinical cases in calves of all breeds under 30 days of age, with pancytopenic haemorrhagic purpura. Calves are vironegative for BVD and BTV, most are seropositive for both viruses antibodies. No specific etiology has been highlighted, but it seems that the syndrome is linked to the ingestion of colostrum immunized against cells of the calf. The syndrome is sporadic, with a prevalence ranging between 1:10,000 and 1:100,000 cattle under one year of age, causing a lethality of 99%. The origin of the pancytopenia is a medullar aplasia. [less ▲]

la pandémie de grippe H1N1, un défi de taille pour le Médecin Généraliste

Conference (2009, September 22)

A panel of biological tests reveals developmental effects of pharmaceutical pollutants on late stage zebrafish embryos.

in Reproductive Toxicology (2012)

Standard toxicological assays using the zebrafish model system evaluate lethality and teratogenicity upon exposure during the first two days after fertilization. We tested the biological effects of ... [more ▼]

Standard toxicological assays using the zebrafish model system evaluate lethality and teratogenicity upon exposure during the first two days after fertilization. We tested the biological effects of several widely used drugs on zebrafish by acute treatment for 24hours starting at late embryonic stages, between 48 and 72hours post-fertilization. For 4 out of 6 compounds, we observed a higher sensitivity of late stage zebrafish embryos for general toxicity (lethality) compared to younger embryos. Morphological defects such as edema, body curvature, delayed growth, decreased heart rate and locomotion were observed for each of the compounds tested, often at sublethal concentrations. Gene expression studies on a set of four selected genes revealed a specific regulatory pattern for the different compounds tested. Our results allow us to compare various toxicological endpoints and may contribute to the design of a rational high throughput approach using the zebrafish model. [less ▲]

La panleucopénie féline : parvovirus félins et canins chez le chat

in Point Vétérinaire (2010), 41

The Panorama and the Labyrinth

in Proceedings of the 4th IASME/WSEAS International Conference on Landscape Architecture (2011)

The experience of gardens is often analyzed in function of the views the garden affords. The actual walk leading to the views is treated as secondary. Yet the views cannot be experienced without the walk ... [more ▼]

The experience of gardens is often analyzed in function of the views the garden affords. The actual walk leading to the views is treated as secondary. Yet the views cannot be experienced without the walk. The paper presents the paradigm of “panorama and labyrinth” to offer an analysis of both aspects of the experience of a garden. [less ▲]

Panorama des démarches qualité : à chaque stratégie son outil.

in Quatrième Carrefour des Productions animales : Les démarches de qualité en production de viandes : Pourquoi ? Pour qui ? (1999, January 27)

Panorama des imaginaires des jeunes au sujet de la société idéale

Article for general public (2008)

Panorama des techniques financières d'évaluation des entreprises

Scientific conference (2009, April 28)

This short conference present a global overview of the different valuation approaches that are now present both in the professional literature and in the academic literature.