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See detailAngiosarcome hépatique chez une patiente ayant présenté une hépatite autoimmune
Reginster, M. A.; Mazy, V.; Waltregny, David ULg et al

in Revue Médicale de Liège (1993), 48(4), 220-3

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See detailAngiosarcome sur lymphoedeme chronique: un cas de syndrome de Stewart-Treves.
Gonne, E.; Collignon, Joëlle ULg; Kurth, William ULg et al

in Revue Médicale de Liège (2009), 64(7-8), 409-13

The Stewart-Treves Syndrome is defined as an angiosarcoma (very aggressive malignant tumor originating from endothelial cells) appearing in a specific clinical setting. This tumor develops in patients ... [more ▼]

The Stewart-Treves Syndrome is defined as an angiosarcoma (very aggressive malignant tumor originating from endothelial cells) appearing in a specific clinical setting. This tumor develops in patients suffering from chronic lymphedema of the upper limb following mastectomy and axillary lymph node dissection for breast cancer. The diagnosis relies on medical history, clinical examination and a histological assesment (biopsy or resection). This syndrome represents a rare clinical entity. Unfortunately, the prognosis is poor. A large surgical resection is the treatment of choice if the patient is a candidate for a surgical resection with a curative intent Radiotherapy is sometimes used as a palliative local treatment. Chemotherapy is only used in more advanced cases, not curable by surgery alone. [less ▲]

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See detailThe angiostatic 16K human prolactin overcomes endothelial cell anergy and promotes leukocyte infiltration via nuclear factor-kappaB activation
Tabruyn, Sébastien ULg; Sabatel, Céline ULg; Nguyen, Ngoc-Quynh-Nhu ULg et al

in Molecular Endocrinology (2007), 21(6), 1422-9

The 16-kDa N-terminal fragment of human prolactin (16K hPRL) is a potent angiostatic factor that inhibits tumor growth in mouse models. Using microarray experiments, we have dissected how the endothelial ... [more ▼]

The 16-kDa N-terminal fragment of human prolactin (16K hPRL) is a potent angiostatic factor that inhibits tumor growth in mouse models. Using microarray experiments, we have dissected how the endothelial-cell genome responds to 16K hPRL treatment. We found 216 genes that show regulation by 16K hPRL, of which a large proportion turned out to be associated with the process of immunity. 16K hPRL induces expression of various chemokines and endothelial adhesion molecules. These expressions, under the control of nuclear factor-kappaB, result in an enhanced leukocyte-endothelial cell interaction. Furthermore, analysis of B16-F10 tumor tissues reveals a higher expression of adhesion molecules (intercellular adhesion molecule 1, vascular cell adhesion molecule 1, or E-selectin) in endothelial cells and a significantly higher number of infiltrated leukocytes within the tumor treated with 16K hPRL compared with the untreated ones. In conclusion, this study describes a new antitumor mechanism of 16K hPRL. Because cellular immunity against tumor cells is a crucial step in therapy, the discovery that treatment with 16K hPRL overcomes tumor-induced anergy may become important for therapeutic perspectives. [less ▲]

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See detailAngiostatic activity of the antitumor cytokine interleukin-21.
Castermans, Karolien ULg; Tabruyn, Sébastien ULg; Zeng, Rong et al

in Blood (2008), 112(13), 4940-7

Interleukin-21 (IL-21) is a recently described immunoregulatory cytokine. It has been identified as a very potent immunotherapeutic agent in several cancer types in animal models, and clinical studies are ... [more ▼]

Interleukin-21 (IL-21) is a recently described immunoregulatory cytokine. It has been identified as a very potent immunotherapeutic agent in several cancer types in animal models, and clinical studies are ongoing. IL-21 belongs to the type I cytokine family of which other members, ie, IL-2, IL-15, and IL-4, have been shown to exert activities on vascular endothelial cells (ECs). We hypothesized that IL-21, in addition to inducing the antitumor immune response, also inhibits tumor angiogenesis. In vitro experiments showed a decrease of proliferation and sprouting of activated ECs after IL-21 treatment. We found that the IL-21 receptor is expressed on vascular ECs. Furthermore, in vivo studies in the chorioallantoic membrane of the chick embryo and in mouse tumors demonstrated that IL-21 treatment disturbs vessel architecture and negatively affects vessel outgrowth. Our results also confirm the earlier suggested angiostatic potential of IL-2 in vitro and in vivo. The angiostatic effect of IL-21 is confirmed by the decrease in expression of angiogenesis-related genes. Interestingly, IL-21 treatment of ECs leads to a decrease of Stat3 phosphorylation. Our research shows that IL-21 is a very powerful antitumor compound that combines the induction of an effective antitumor immune response with inhibition of tumor angiogenesis. [less ▲]

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See detailThe Angiostatic Protein 16K Human Prolactin Significantly Prevents Tumor-Induced Lymphangiogenesis by Affecting Lymphatic Endothelial Cells.
Kinet, Virginie; Castermans, K; Herkenne, Stéphanie ULg et al

in Endocrinology (2011)

The 16-kDa angiostatic N-terminal fragment of human prolactin (16K hPRL) has been reported to be a new potent anticancer compound. This protein has already proven its efficiency in several mouse tumor ... [more ▼]

The 16-kDa angiostatic N-terminal fragment of human prolactin (16K hPRL) has been reported to be a new potent anticancer compound. This protein has already proven its efficiency in several mouse tumor models in which it prevented tumor-induced angiogenesis and delayed tumor growth. In addition to angiogenesis, tumors also stimulate the formation of lymphatic vessels, which contribute to tumor cell dissemination and metastasis. However, the role of 16K hPRL in tumor-induced lymphangiogenesis has never been investigated. We establish in vitro that 16K hPRL induces apoptosis and inhibits proliferation, migration, and tube formation of human dermal lymphatic microvascular endothelial cells. In addition, in a B16F10 melanoma mouse model, we found a decreased number of lymphatic vessels in the primary tumor and in the sentinel lymph nodes after 16K hPRL treatment. This decrease is accompanied by a significant diminished expression of lymphangiogenic markers in primary tumors and sentinel lymph nodes as determined by quantitative RT-PCR. These results suggest, for the first time, that 16K hPRL is a lymphangiostatic as well as an angiostatic agent with antitumor properties. [less ▲]

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See detailAngiotropic lymphoma of proliferating systematized angioendotheliomatosis type
Pierard, Gérald ULg; Soyeur-Broux, Monique ULg; FRIDMAN, Viviana ULg et al

in Annales de Dermatologie et de Vénéréologie (1988), 115(3), 333-336

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See detailAngles corniculaires et de demi-cercle chez Euclide
Bair, Jacques ULg; Henry, Valérie

in Les angles sous tous les angles (2015)

Dans cet article, on examine comment Euclide présentait, dans ses Eléments, les notions liées au concept d'angle dans le plan. Il considérait des angles mixtilignes, en particulier corniculaires et de ... [more ▼]

Dans cet article, on examine comment Euclide présentait, dans ses Eléments, les notions liées au concept d'angle dans le plan. Il considérait des angles mixtilignes, en particulier corniculaires et de demi-cercle, qui peuvent être de nos jours exploités pour introduire les nombres hyperréels intervenant en analyse non standard. [less ▲]

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See detailAngles corniculaires et de demi-cercle chez Euclide
Bair, Jacques ULg; Henry, Valérie ULg

in Tangente. Hors-série (2014), 53

Les angles datent de l’Antiquité : ils sont présents dans le célèbre ouvrage "Les Éléments" d’Euclide. En partant des "Commentaires" de Proclus, nous présentons la façon dont Euclide introduisait le ... [more ▼]

Les angles datent de l’Antiquité : ils sont présents dans le célèbre ouvrage "Les Éléments" d’Euclide. En partant des "Commentaires" de Proclus, nous présentons la façon dont Euclide introduisait le concept d'angle et sa distinction entre les angles rectilignes et mixtilignes. Les cas des angles corniculaires et de demi-cercle sont spécialement traités. [less ▲]

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See detailLes angles corniculaires et l'infiniment petit
Bair, Jacques ULg; Henry, Valérie ULg

in Tangente Sup (2006), 31(mai-juin), 4-7

Nous mettons en évidence le fait que des angles entre un demi-cercle et une droite tangente mène au concept d'infiniment petit.

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See detailAngles corniculaires et nombres superréels
Bair, Jacques ULg; Henry, Valérie ULg

in Bulletin of the Belgian Mathematical Society Simon Stevin (2008), 15(1), 77-86

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See detailL'Angleterre et la Russie en Orient
De Laveleye, Émile ULg

in Revue des Deux Mondes (Paris, France : 1948) (1880)

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See detailAnglo-Belgian relations, past and present
Vander Linden, Herman; Hamélius, Paul ULg

Book published by Constable and Company (1918)

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See detailAnglophones et Québécois, Flamands et Francophones : La répartition du pouvoir au sein du gouvernement belge et canadien
Reuchamps, Min ULg

Conference (2007, May 03)

In divided societies, such as Belgium and Canada, the federal principle and consociational power-sharing have been implemented in order to accommodate ethno-linguistic communities. The combination of ... [more ▼]

In divided societies, such as Belgium and Canada, the federal principle and consociational power-sharing have been implemented in order to accommodate ethno-linguistic communities. The combination of Daniel Elazar’s seminal work on federalism in plural societies and of Arend Lijphart’s on consociationalism offers a theoretical framework which can be usefully applied to study the distribution of power between the two main ethno-linguistic communities at the highest level of the state. Using the existing “model of points” and the author’s own “model of the weight of ministerial portfolios”, this paper explores the linguistic composition of the federal governments in both countries over the last thirty years (1970-2006). Whereas the Belgian Constitution has required since 1970 that the federal cabinet be staffed by an equal number of Flemish and Francophone ministers, the Canadian Constitution does not require such a linguistic parity and therefore leaves a greater freedom for the composition of the government. On this background, two logics may explain the linguistic composition in the two cases: a logic of transaction between the two main communities and a logic of representation. The paper opens, on the one hand, with the elaboration of the theoretical framework combining the works of Elazar and Lijphart and, on the other hand, with the construction of the two models. The framework and the models are applied to each case, emphasizing the logic of transaction and the logic of representation. On the basis of this examination, this paper concludes by suggesting that Flemish and Francophone Belgians as well and English and French Canadians benefit from the composition of the federal cabinet. The conclusion opens—new—ways and means to hinder political tensions in plural societies through the institutional arrangement. [less ▲]

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See detailAngoff’s Delta method revisited: improving the DIF detection under small samples
Magis, David ULg; Facon, Bruno

in British Journal of Mathematical & Statistical Psychology (2012), 65

Most of the methods for detecting differential item functioning (DIF) are suitable when the sample sizes are sufficiently large to validate the null statistical distributions. There is no guarantee ... [more ▼]

Most of the methods for detecting differential item functioning (DIF) are suitable when the sample sizes are sufficiently large to validate the null statistical distributions. There is no guarantee, however, that they still perform adequately when there are few respondents in the focal group or in both the reference and the focal group. Angoff’s Delta plot is a potentially useful alternative for small-sample DIF investigation, but it suffers from improper DIF flagging criterion. The purpose of this paper is to improve this classification rule under mild statistical assumptions. This improvement yields a modified Delta plot with an adjusted DIF flagging criterion for small samples. A simulation study was conducted to compare the modified Delta plot to both the classical Delta plot approach and the Mantel-Haenszel method. It is concluded that the modified Delta plot is consistently less conservative and more powerful than the usual Delta plot, and is also less conservative and more powerful than the Mantel-Haenszel method as long as at least one group of respondents is small. [less ▲]

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See detailL'angoisse de la mort dans Sein und Zeit
Pieron, Julien ULg

Scientific conference (2008, April 18)

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See detailAngoisse et mort dans Sein und Zeit
Pieron, Julien ULg

in Bulletin d'Analyse Phénoménologique (2008), 4(5), 1-19

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See detailL'angoisse minimaliste
Demoulin, Laurent ULg

in Indications. La Revue des Romans (1993), 1(50), 27-31

Description de quelques caractéristiques du roman français contemporain.

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See detailL'angor
Legrand, Victor ULg

in Revue Médicale de Liège (2004), 59(4), 186-9

The medical history is the cornerstone of the diagnosis of chest pain. In presence of angina like symptoms, the diagnosis of coronary artery disease must be assertained by rest and exercise ECG ... [more ▼]

The medical history is the cornerstone of the diagnosis of chest pain. In presence of angina like symptoms, the diagnosis of coronary artery disease must be assertained by rest and exercise ECG, eventually coupled with a stress echo or scintigraphy. Coronary angiography remains the ultimate diagnostic procedure despite recent advances in CT scan or MRI technologies. Beside symptomatic treatment aiming to reduce metabolic demand by medication or to improve revascularisation by surgery or percutaneous intervention, the actual therapeutic approach involves therapies aiming to stop atherosclerosis such as strict correction of coronary risk factors, use of statines, ACE inhibitors and antiplatelet agents. [less ▲]

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See detailAngot salue Guibert
Demoulin, Laurent ULg

in Critique : Revue Générale des Publications Françaises et Etrangères (2002), 663-664

Le roman L'Inceste de Christine Angot s'ouvre presque sur les mêmes phrases que le roman A l'ami qui ne m'a pas sauvé la vie d'Hervé Guibert. Quelle est la valeur de ce détournement textuel et quel rôle ... [more ▼]

Le roman L'Inceste de Christine Angot s'ouvre presque sur les mêmes phrases que le roman A l'ami qui ne m'a pas sauvé la vie d'Hervé Guibert. Quelle est la valeur de ce détournement textuel et quel rôle joue-t-il dans le roman d'Angot? [less ▲]

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See detailAngry faces hold the eyes
Belopolsky, Artem; Devue, Christel ULg; Theeuwes, Jan

in Visual Cognition (2011), 19

Efficient processing of complex social and biological stimuli associated with threat is crucial for survival. Previous studies have suggested that threatening stimuli such as angry faces not only capture ... [more ▼]

Efficient processing of complex social and biological stimuli associated with threat is crucial for survival. Previous studies have suggested that threatening stimuli such as angry faces not only capture visual attention, but also delay the disengagement of attention from their location. However, in the previous studies disengagement of attention was measured indirectly and was inferred on the basis of delayed manual responses. The present study employed a novel paradigm that allows to directly examine the delayed disengagement hypothesis by measuring the time it takes to disengage the eyes from threatening stimuli. The results showed that participants were indeed slower to make an eye movement away from an angry face presented at fixation than from either a neutral or a happy face. This finding provides converging support that the delay in disengagement of attention is an important component of processing threatening information. [less ▲]

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