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See detailApplication of data mining to optimize settings for generator tripping and load shedding system in emergency control at Hydro-Quebec
Huang, J. A.; Harrison, S.; Vanier, G. et al

in COMPEL (2004), 23(1 Sp. Iss. SI), 21-34

This paper describes the on-going work done by Hydro-Quebec to optimize the settings of automatic devices installed in its main power plants to maintain secure operation under extreme contingencies. The ... [more ▼]

This paper describes the on-going work done by Hydro-Quebec to optimize the settings of automatic devices installed in its main power plants to maintain secure operation under extreme contingencies. The automatic generator tripping and load shedding system (RPTC) described in this paper is installed at the Churchill Falls hydroelectric power plant (5,500 MW) in Labrador. Data mining techniques such as decision trees and regression trees have been used. Real time snapshots of the Hydro-Quebec power system collected over a 5 year period have been used to generate large amounts of results by transient stability simulations. The processing of these data has been done using software developed by the University of Liege. This approach gives the most relevant parameters and finds optimal settings for the RPTC system, minimizing the number of tripped generator units while maintaining the same performance in terms of security coverage. New operation rules can thus be established. [less ▲]

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See detailAPPLICATION OF DESIGN OF EXPERIMENTS AND DESIGN SPACE METHODOLOGY FOR THE HPLC-UV SEPARATION OPTIMIZATION OF APORPHINE ALKALOIDS FROM LEAVES OF Spirospermum penduliflorum THOUARS
Rafamantanana, Mamy; Debrus, Benjamin ULg; Raoelison, Guy et al

in Journal of Pharmaceutical & Biomedical Analysis (2012), 62

Spirospermum penduliflorum Thouars (Menispermaceae) is an endemic species of Madagascar traditionally used as vasorelaxant. Recently, two aporphine alkaloids known to possess antihypertensive activity ... [more ▼]

Spirospermum penduliflorum Thouars (Menispermaceae) is an endemic species of Madagascar traditionally used as vasorelaxant. Recently, two aporphine alkaloids known to possess antihypertensive activity (dicentrine and neolitsine) were isolated and identified from the leaves of this plant. In the present study, a HPLC-UV method allowing the separation of all alkaloids and the quantification of dicentrine in the alkaloidic extract of leaves was developed using design of experiments and design space methodology. Three common chromatographic parameters (i.e. the mobile phase pH, the initial proportion of methanol and the gradient slope) were selected to construct a full factorial design of 36 experimental conditions. The times at the beginning, the apex (i.e. the retention time) and the end of each peak were recorded and modelled by multiple linear equations. The corresponding residuals were normally distributed which confirmed that the models can be used for the prediction of the retention times and to optimize the separation. The optimal separation was predicted at pH 3, with a gradient starting at 32% of methanol and a gradient slope of 0.42%/min. Good agreement was obtained between predicted and experimental chromatograms. The method was also validated using total error concept. Using the accuracy profile approach, validation results gave a LOD and LOQ for dicentrine of 3 µg/ml and 10 µg/ml, respectively. A relative standard deviation for intermediate precision lower than 10% was obtained. This method was found to provide accurate results in the concentration range of 10 µg/ml to 75 µg/ml of dicentrine and is suitable for routine analysis. [less ▲]

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See detailApplication of deterministic and stochastic analysis to calculate a stadium with pressure measurements in wind tunnel
Blaise, Nicolas ULg; Denoël, Vincent ULg; De Ville De Goyet, Vincent ULg et al

in Proceedings of the 8th International Conference on Structural Dynamics EURODYN 2011 (2011, July)

This paper aims at comparing different analysis methods in the design of a roof subjected to buffeting wind forces. The specificity of this study is that pressures acting on the stadium roof are measured ... [more ▼]

This paper aims at comparing different analysis methods in the design of a roof subjected to buffeting wind forces. The specificity of this study is that pressures acting on the stadium roof are measured in a wind tunnel. The key idea is to fit a probabilistic model onto the measured data and to perform the stochastic analysis as a usual buffeting analysis. [less ▲]

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See detailApplication of different mathematical models for the prediction of bone regeneration in an in vivo bone chamber
Van Oosterwyck, Hans; Geris, Liesbet ULg; Gerisch, A. et al

in Lecture notes of workshop Numerical models of bone adaptation and repair (2004)

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See detailApplication of discontinuous Galerkin methods to shells and fracture of thin structures
Noels, Ludovic ULg

Scientific conference (2010, January)

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See detailApplication of dual cyclodextrin systems in capillary electrophoresis enantioseparations.
Servais, Anne-Catherine ULg; Fillet, Marianne ULg

in Methods in Molecular biology 970: Chiral Separations (2013)

The enantioseparation of acidic and neutral compounds can be successfully achieved in capillary electrophoresis (CE) using dual cyclodextrin (CD) systems. This chapter describes how to separate the ... [more ▼]

The enantioseparation of acidic and neutral compounds can be successfully achieved in capillary electrophoresis (CE) using dual cyclodextrin (CD) systems. This chapter describes how to separate the enantiomers of acidic or neutral substances using dual CD systems made up of a negatively charged CD derivative, i.e., sulfobutyl-beta-CD (SB-beta-CD) or carboxymethyl-beta-CD (CM-beta-CD), in combination with a neutral one, namely, heptakis(2,3,6-tri-O-methyl)-beta-CD (TM-beta-CD). An acidic compound (carprofen) and a weakly acidic drug (pentobarbital) were selected as model compounds. [less ▲]

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See detailThe application of EIA/SEA procedures to the urban cultural heritage active conservation
Teller, Jacques ULg; Dupagne, Albert ULg

in Proc. of 5th European Commission Conference on Research for Protection, Conservation and Enhancement of Cultural Heritage (2002)

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See detailApplication of Eurocode 3 to steel connections with four bolts per horizontal row
Demonceau, Jean-François ULg; Weynand, Klaus; Jaspart, Jean-Pierre ULg et al

in Batista, E.; Vellasco, P.; de Lima, L. (Eds.) Proceedings of the SDSS'Rio 2010 conference (2010, September)

Eurocode 3 Part 1-8 provides detailed application rules for the design of bolted end-plate connections. Although these rules apply to connections with any number of bolt rows, they are limited to ... [more ▼]

Eurocode 3 Part 1-8 provides detailed application rules for the design of bolted end-plate connections. Although these rules apply to connections with any number of bolt rows, they are limited to configurations with two bolts in each row. However, it is sometimes more economical to place four bolts in one row. This configuration is commonly met in different countries in Europe and, in particular, in Germany. The theoretical model on which the Eurocode 3 application rules are founded is general and can be potentially applied to connections with four bolts per row. However, specific design rules need to be developed. In the present paper, easy-to-apply analytical design rules aimed at predicting the mechanical properties of connections with four bolts per row and in full agreement with the Eurocode 3 approach are detailed. Validations through comparisons to experimental test results recently performed in the framework of a German national project are also presented. [less ▲]

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See detailApplication of experimental design for the HPLC-UV-MS separation of aporphine alkaloids from leaves of Spirospermum Penduliflorum thouars
Rafamantanana, Mamy H.; Debrus, Benjamin ULg; Raoelison, Guy E. et al

Poster (2010, September)

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See detailApplication of forensic science technique to the management of an endangered horse population
Bömcke, Elisabeth ULg; Gengler, Nicolas ULg

in Journal of Animal Science (2008), 86(E-suppl.2), 433

Implementing conservation strategies needs the knowledge of relationships inside the concerned population. The aim of the study was to find tools to help breeders to manage their horse population. The ... [more ▼]

Implementing conservation strategies needs the knowledge of relationships inside the concerned population. The aim of the study was to find tools to help breeders to manage their horse population. The Skyros pony is an indigenous Greek breed. The breed risk status is defined as critical-maintained according to the criteria from the Food and Agriculture Organization. Partial pedigree information is available, but its quality is poor as the average number of generation-equivalents is under 0.8 for the first known generation and under 1.4 for the second to the fifth. Further, 99 living individuals were genotyped at 16 microsatellite loci in order to check the registered parentage. For ungenotyped animals, conditional expectation of gene contents was calculated given molecular and pedigree data. As said in other studies, the animal genetics literature often seems unaware of relevant developments in human genetics (and conversely). In this study, an approach called Familial Searching was tested. This is used in forensic science, in addition to matching DNA evidence directly to criminal profiles, to search for people (present in a database) who are related to an individual that left DNA evidence at a scene of crime. This method is based on the calculation of likelihood ratios (LR) between genotype of an individual and genotypes of each other individuals of the database. The pedigree was used as ‘local’ prior information, i.e. relating to specific pairs of individuals. General knowledge about the studied population (generation interval, sexual maturity, …) was considered as ‘global’ prior information. Including prior information reduced the number of comparisons from over 50%. First results showed that the parents were always classified into the 5 highest LR. These results simplified parentage verifications, it allowed the detection of 90% of false parentage (LR=0). New links were created in the pedigree through detection of unregistered parents, what involved a reduction of the percentage of animals with one or both unknown parents and consequently an increase of the number of generation-equivalents. The pedigree of the breed was thus improved. [less ▲]

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See detailApplication of four lead systems to quantitative electrocardiography in calves
Amory, Hélène ULg; Rollin, Frédéric ULg; Lekeux, Pierre ULg

in Archives Internationales de Physiologie et de Biochimie (1990)

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See detailAn application of fuzzy random variables to control charts
Faraz, Alireza ULg; Shapirob, Arnold

in Fuzzy Sets & Systems (2010), 161(20), 26842694

The two most significant sources of uncertainty are randomness and incomplete information. In real systems, we wish to monitor processes in the presence of these two kinds of uncertainty. This paper aims ... [more ▼]

The two most significant sources of uncertainty are randomness and incomplete information. In real systems, we wish to monitor processes in the presence of these two kinds of uncertainty. This paper aims to construct a fuzzy statistical control chart that can explain existing fuzziness in data while considering the essential variability between observations. The proposed control chart is an extension of Shewhart ¯X − S2 control charts in fuzzy space. The proposed control chart avoids defuzzification methods such as fuzzy mean, fuzzy mode, fuzzy midrange, and fuzzy median. It is well known that using different representative values may cause different conclusions to be drawn about the process and vague observations to be reduced to exact numbers, thereby reducing the informational content of the original fuzzy sets. The out-of-control states are determined based on a fuzzy in-control region and a simple and precise graded exclusion measure that determines the degree to which fuzzy subgroups are excluded from the fuzzy in-control region. The proposed chart is illustrated with a numerical example. [less ▲]

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