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See detailAnalytical Validation of Diasorin Liaison and Roche Elecsys Methods for the Determination of Osteocalcin
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Carlisi, Ignazia ULg et al

in Journal of Bone and Mineral Research (2008, September), 23

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See detailAnalytical validation of potentiometric method for cetirizinium ion
Rachidi, Mohamed ULg; Digua, K.; Hubert, Philippe ULg et al

in Analytical Letters (2006), 39(8), 1699-1708

Accuracy and reliability of the analytical results are crucial for ensuring quality, safety, and efficacy of pharmaceutical products. However, to ensure these criteria, analytical validation is required ... [more ▼]

Accuracy and reliability of the analytical results are crucial for ensuring quality, safety, and efficacy of pharmaceutical products. However, to ensure these criteria, analytical validation is required. In this matter, many official documents describing the criteria of validation are available. However, these concern mainly chromatography analysis and bio-analytical methods of pharmaceutical products, but they do not propose any experimental protocol for direct potentiometric methods using ion-selective electrodes applied in pharmaceutical analysis. In this work, we are proposing a validation strategy based on the normative and regulatory guidelines applied to a potentiometric method with a polymeric membrane selective to cetirizine dihydrochloride. The statistical analysis obtained from raw data is described for all steps of this protocol. Also this validated method was successfully applied to the determination of cetirizine in pharmaceutical preparations using direct potentiometry with a mean relative standard deviation of 0.57% and a mean recovery of 99.63%. [less ▲]

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See detailAnalytical validation of the Abbott Architect urine NGAL
Cavalier, Etienne ULg; Saarbach, D.; Bekaert, Anne-Catherine ULg et al

in Clinical Chemistry (2010, June), 56(S6), 96

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See detailAnalytical validation of the BAP OSTASE on Liaison (DiaSorin).
Cavalier, Etienne ULg; Rozet, Eric ULg; Carlisi, Ignazia ULg et al

in Clinical Chemistry & Laboratory Medicine (2010), 48(1), 67-72

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See detailAnalytical validation of the Liaison Calcitonin_II-Gen (DiaSorin)
Cavalier, Etienne ULg; Carlisi, Ignazia ULg; Bekaert, Anne-Catherine ULg et al

in Clinical Chemistry & Laboratory Medicine (2011), 49(2), 271-275

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See detailAnalytical validation of the Liaison hGH assay (DiaSorin)
Keutgens, Aurore ULg; Ho, Thi Thanh Giang ULg; Cavalier, Etienne ULg

in European NeuroEndocrine Association (2010, September)

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See detailAnalytical validation of the new plasma calibrated Accu-Chek (R) Test Strips (Roche Diagnostics)
Meex, Cécile ULg; Poncin, José ULg; Chapelle, Jean-Paul ULg et al

in Clinical Chemistry & Laboratory Medicine (2006), 44(11), 1376-1378

Background: The Accu-Chek Inform glucose monitor is a point-of-care system for testing blood glucose. New test strips, calibrated to deliver glucose plasma-like values, were launched on the market in May ... [more ▼]

Background: The Accu-Chek Inform glucose monitor is a point-of-care system for testing blood glucose. New test strips, calibrated to deliver glucose plasma-like values, were launched on the market in May 2005. The aim of our study was to perform analytical validation of these new strips. Methods: We compared the new plasma strips with whole blood strips; results for the plasma strips with plasma values obtained using a clinical analyzer and with whole blood values given by the glucose electrode of a blood gas analyzer; and the influence of the type of blood (capillary or venous) on the results obtained by the glucose monitor with the plasma calibrated strips. Results: Plasma strips give on average 7% higher results than the previous whole blood strips. However, the results given by the plasma strips on capillary whole blood, even if well correlated, are not completely comparable with those given by an analyzer for venous plasma. Nevertheless, these plasma strips and the glucose electrode of a blood gas analyzer give comparable results. Conclusions: Accu-Chek Inform plasma strips are a good method for monitoring of blood glucose values in patients with diabetes. [less ▲]

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See detailAnalytical validation of the new version of the Liaison N-Tact PTH assay
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Carlisi, Agnès et al

in Clinical Chemistry & Laboratory Medicine (2007), 45(1), 105-107

We performed analytical validation of the new version of the Liaison N-Tact PTH (parathormone) assay according to NCCLS guidelines and compared this new generation of reagent with the Roche Elecsys PTH ... [more ▼]

We performed analytical validation of the new version of the Liaison N-Tact PTH (parathormone) assay according to NCCLS guidelines and compared this new generation of reagent with the Roche Elecsys PTH assay. We showed that this new version is a sensitive and precise method with good recovery. Significant carryover was observed, but with limited clinical implications. We demonstrated that the new version of the Liaison PTH is in reasonably good agreement with the Roche Elecsys PTH assay, and as we observed no differences in a hemodialyzed population, moving from one method to the other should not affect the daily follow-up of patients. However, one should be cautious with the highest values (> 500 pg/mL). We established reference intervals of 12-54 pg/mL for the Liaison and 14-52 pg/mL for the Elecsys assay. [less ▲]

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See detailAnalytical, physiologic, and clinical validation of a radioimmunoassay for measurement of procollagen type III amino terminal propeptide in serum and bronchoalveolar lavage fluid obtained from dogs
Schuler, S.; Valentin, S.; Remy, Bernadette et al

in American Journal of Veterinary Research (2006), 67(5), 749-755

OBJECTIVE: To validate a radioimmunoassay for measurement of procollagen type III amino terminal propeptide (PIIINP) concentrations in canine serum and bronchoalveolar lavage fluid (BALF) and investigate ... [more ▼]

OBJECTIVE: To validate a radioimmunoassay for measurement of procollagen type III amino terminal propeptide (PIIINP) concentrations in canine serum and bronchoalveolar lavage fluid (BALF) and investigate the effects of physiologic and pathologic conditions on PIIINP concentrations. SAMPLE POPULATION: Sera from healthy adult (n = 70) and growing dogs (20) and dogs with chronic renal failure (CRF; 10), cardiomyopathy (CMP; 12), or degenerative valve disease (DVD; 26); and sera and BALF from dogs with chronic bronchopneumopathy (CBP; 15) and healthy control dogs (10 growing and 9 adult dogs). PROCEDURE: A radioimmunoassay was validated, and a reference range for serum PIIINP (S-PIIINP) concentration was established. Effects of growth, age, sex, weight, CRF, and heart failure on S-PIIINP concentration were analyzed. In CBP-affected dogs, S-PIIINP and BALF-PIIINP concentrations were evaluated. RESULTS: The radioimmunoassay had good sensitivity, linearity, precision, and reproducibility and reasonable accuracy for measurement of S-PIIINP and BALF-PIIINP concentrations. The S-PIIINP concentration reference range in adult dogs was 8.86 to 11.48 mug/L. Serum PIIINP concentration correlated with weight and age. Growing dogs had significantly higher S-PIIINP concentrations than adults, but concentrations in CRF-, CMP-, DVD-, or CBP-affected dogs were not significantly different from control values. Mean BALF-PIIINP concentration was significantly higher in CBP-affected dogs than in healthy adults. CONCLUSIONS AND CLINICAL RELEVANCE: In dogs, renal or cardiac disease or CBP did not significantly affect S-PIIINP concentration; dogs with CBP had high BALF-PIIINP concentrations. Data suggest that the use of PIIINP as a marker of pathologic fibrosis might be limited in growing dogs. [less ▲]

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See detailAnalytical, physiological and clinical validation of a radioimmunoassay for serum Procollagen Type-III aminoterminal peptide in the dog
Schuller, S.; Valentin, S.; Remy, B. et al

in 14th ESVIM Meeting - Barcelona - Espagne (2004, June)

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See detailAn analytical-numerical method based on static equivalent load for the evaluation of maximum dynamic stresses in HV Substation.
Miri; Kuhner, A.; Lilien, Jean-Louis ULg et al

in Proceedings of the 7th ESCC (1996, September)

Short-circuit mechnaical effects in substations may be analysed by numerical methods. It helps to better define equivalent static loads qhich may be used for design of supporting structures during such ... [more ▼]

Short-circuit mechnaical effects in substations may be analysed by numerical methods. It helps to better define equivalent static loads qhich may be used for design of supporting structures during such dynamic loading. [less ▲]

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See detailAnalytique versus dialectique
Leclercq, Bruno ULg

Conference (2007, November 09)

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See detailAnalytique versus dialectique. Y a-t-il encore de la place pour deux dans la logique contemporaine ?
Leclercq, Bruno ULg

in Counet, Jean-Michel (Ed.) Figures de la dialectique. Histoire et perspectives contemporaines (2010)

Detailed reference viewed: 40 (3 ULg)