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See detailHow to measure quality in job transitions?
Levêque, Audrey ULg; Orianne, Jean-François ULg; Pichault, François ULg

Conference (2011, July 08)

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See detail"How to measure quality in job transitions?"
Levêque, Audrey ULg; Orianne, Jean-François ULg; Pichault, François ULg

Conference (2011, October 27)

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See detailHow to minimise production costs at the preliminary design stage - scantling optimization
Rigo, Philippe ULg

in IMDC’2003, Eighth International Marine Design Conference, Grèce,Vol2 (2003, May)

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See detailHow to monitor NF-kappaB activation after photodynamic therapy.
Coupienne, Isabelle ULg; Piette, Jacques ULg; Bontems, Sébastien ULg

in Methods in Molecular Biology (Clifton, N.J.) (2010), 635

The nuclear factor-kappa B (NF-kappaB) is a multipotent factor involved in many cellular processes such as inflammation, immune response and embryonic development and it can be activated by a large number ... [more ▼]

The nuclear factor-kappa B (NF-kappaB) is a multipotent factor involved in many cellular processes such as inflammation, immune response and embryonic development and it can be activated by a large number of stimuli. Consequently, this transcription factor plays a pivotal role in many natural processes but also in different pathologies. For several years, photodynamic therapy (PDT) has emerged as an attractive alternative approach for the treatment of different affections involving various forms of cancer and an increasing number of reports have highlighted the activation of the NF-kappaB following PDT treatment. Furthermore, it has been shown that the mechanism of activation of the NF-kappaB as well as its target genes depends on the nature of the photosensitizers and the cell type used. As this transcription factor is known to be a key regulator of the immune response but also controls cell survival and proliferation, it is important to assess its activation status and its impact on the target genes. In this review, we will present different techniques allowing identification of the activation status of this factor, from the degradation of its inhibitor in the cytoplasm to its ability to induce the expression of a reporter gene under the control of a target promoter. As a working model we will present results obtained from a 5-aminolevulinic acid-PDT treatment on cervix adenocarcinoma cells. [less ▲]

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See detailHow to optimally load a set of containers into an aircraft
Schyns, Michael ULg; Limbourg, Sabine ULg; Laporte, Gilbert

E-print/Working paper (2012)

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See detailHow to optimize physicians' communication skills in cancer care: Results of a randomized study assessing the usefulness of posttraining consolidation workshops
Razavi, D.; Merckaert, I.; Marchal, Sylvie ULg et al

in Journal of Clinical Oncology (2003), 21(16), 3141-3149

Purpose: Although there is wide recognition of the usefulness of improving physicians' communication skills, no studies have yet assessed the efficacy of post-training consolidation workshops. This study ... [more ▼]

Purpose: Although there is wide recognition of the usefulness of improving physicians' communication skills, no studies have yet assessed the efficacy of post-training consolidation workshops. This study aims to assess the efficacy of six 3-hour consolidation workshops conducted after a 2.5-day basic training program. Methods: Physicians, after attending the basic training program, were randomly assigned to consolidation workshops or to a waiting list. Training efficacy was assessed through simulated and actual patient interviews that were audiotaped at baseline and after consolidation workshops for the consolidation-workshop group, and approximately 5 months after the end of basic training for the waiting-list group. Communication skills were assessed according to the Cancer Research Campaign Workshop Evaluation Manual. Patients' perceptions of communication skills improvement were assessed using a 14-item questionnaire. Results : Sixty-three physicians completed the training program. Communication skills improved significantly more in the consolidation-workshop group compared with the waiting-list group. In simulated interviews, group-by-time repeated measures analysis of variance showed a significant increase in open and open directive questions (P =.014) and utterances alerting patients to reality (P =.049), as well as a significant decrease in premature reassurance (P =.042). In actual patient interviews, results revealed a significant increase in acknowledgments (P =.022) and empathic statements (P =.009), in educated guesses (P =.041), and in negotiations (P =.008). Patients interacting with physicians who benefited from consolidation workshops reported higher scores concerning their physicians' understanding of their disease (P =.004). Conclusion: Consolidation workshops further improve a communication skills training program's efficacy and facilitate the transfer of acquired skills to clinical practice. [less ▲]

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See detailHow to perform the diagnosis in a case with anemia ?
Amory, Hélène ULg

in Amory, Hélène (Ed.) In proceedings of the II Encontro de Formação da Ordem dos Médicos Veterinários (2011, October 08)

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See detailHow to perform the diagnosis in a case with icterus ?
Amory, Hélène ULg

in In proceedings of the II Encontro de Formação da Ordem dos Médicos Veterinários (2011, October 08)

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See detailHow to perform the most minimal invasive cholecystectomy?
DETRY, Olivier ULg

Conference (2013, September 20)

Twenty years ago, laparoscopy has totally transformed the surgical approach of the gallbladder. For those who were not in surgery at that time, it has to be reminded that most open cholecystectomies ... [more ▼]

Twenty years ago, laparoscopy has totally transformed the surgical approach of the gallbladder. For those who were not in surgery at that time, it has to be reminded that most open cholecystectomies performed in the 80’s required nasogastric tube for several days, surgical drain, and 5 to 8 days of hospitalisation. For these obvious advantages, laparoscopic cholecystectomy has become the “Gold Standard” without evidence by a randomised controlled study comparing open and laparoscopic techniques. These last years, some groups proposed variations of laparoscopic cholecystectomies that they presented as less invasive. In robotic surgery, the Da-Vinci device has been proposed without significant improvement since more than 10 years. To date, no interest of this Da-Vinci robot has been demonstrated in abdominal surgery. Its cost for acquisition, its yearly fee and the cost for each use render its use without proof of results totally inappropriate. Single-Incision Laparoscopic Surgery (SILS) has also been described to perform cholecystectomy with only one larger umbilical incision. Until now, no superiority of SILS on classical cholecystectomy has been demonstrated. The Natural Orifice Transluminal Endoscopic Surgery (NOTES) proposes to use the vagina, the stomach or the colon to remove the gallbladder. No prospective controlled comparison has proved the superiority of these approaches that sometimes do not reach common sense or usual surgical principles. What is a minimal invasive cholecystectomy? A safe and un expensive cholecystectomy, with a good anatomical exposure, a cholangiography, and a good surgical comfort allowing to perform several procedures in the same day; a cholecystectomy that can be performed as a day-case without complications; a cholecystectomy that can be performed laparoscopically in acute settings; a cholecystectomy without the risk of postoperative incisional hernia. In necessary, in young and thin woman, laparoscopic cholecystectomy may be performed using 2 mm trocars that allow a good triangulation but with minimal scars. [less ▲]

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See detailHow to prescribe parenteral nutrition in clinical difficulties
SENTERRE, Thibault ULg

in Congress of the Portuguese Neonatal Society National (2012)

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See detailHow to prevent bankruptcy in Belgian SMEs ? Towards the implementation of an effective process to detect and assist failing SMEs
Van Caillie, Didier ULg

Conference given outside the academic context (2006)

This conference discusses why it's crucial, in an open economy such as the Belgian one, to prevent business failure in SMEs and to assist entrepreneurs to overcome their difficulties. It insists on the ... [more ▼]

This conference discusses why it's crucial, in an open economy such as the Belgian one, to prevent business failure in SMEs and to assist entrepreneurs to overcome their difficulties. It insists on the role of Public Authorities in assisting entrepreneurs to detect and correct as soon as possible the potential causes of failure. [less ▲]

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See detailHow to rapidly increase the overproduction of a recombinant enzyme?
Georlette, Daphné; D'Amico, Salvino; Anderlei, T. et al

Poster (2001)

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See detailHow to remain nonfolded and pliable: the linkers in modular alpha-amylases as a case study
Feller, Georges ULg; Dehareng, Dominique ULg; Da Lage, Jean-Luc

in FEBS Journal (2011), 278

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See detailHow to reveal the amazing soil microbial diversity ?
Degrune, Florine ULg

Scientific conference (2014, May 22)

Detailed reference viewed: 24 (2 ULg)