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See detailLaminin promotes cerebellar granule cells migration in vitro and is synthesized by cultured astrocytes
SELAK, Ivan ULg; Foidart, Jean-Michel ULg; Moonen, Gustave ULg

in Developmental Neuroscience (1985), 7(5-6), 278-285

Newborn rat cerebellum microexplants have been used as a model to study neuronal migration. Laminin in a substrate-bound form modifies extensively the migratory behavior of the neurones, an effect which ... [more ▼]

Newborn rat cerebellum microexplants have been used as a model to study neuronal migration. Laminin in a substrate-bound form modifies extensively the migratory behavior of the neurones, an effect which is blocked if antilaminin antibodies are present during the assay. 35S methionine incorporation followed by SDS-PAGE electrophoresis, fluorography and immunoprecipitation with antilaminin antibodies allowed to demonstrate that laminin is synthesized and secreted by cultured newborn rat cerebellum as well as by cultured newborn rat cerebral cortex astrocytes. [less ▲]

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See detailLaminin receptor complementary DNA-deduced synthetic peptide inhibits cancer cell attachment to endothelium.
Castronovo, Vincenzo ULg; Taraboletti, G.; Sobel, M. E.

in Cancer Research (1991), 51(20), 5672-8

Stable attachment of cancer cells to the endothelium is a key step in the formation of metastasis. In this study, we have investigated the possibility that interaction between laminin and its Mr 67,000 ... [more ▼]

Stable attachment of cancer cells to the endothelium is a key step in the formation of metastasis. In this study, we have investigated the possibility that interaction between laminin and its Mr 67,000 high-affinity receptor (67 LR) could play a major role in this process. Scatchard analysis of laminin-binding studies showed that bovine aortic endothelial cells exhibit 46,000 high-affinity receptors that mediate, at least in part, the attachment of highly invasive melanoma cells. This endothelial cell-melanoma cell interaction was significantly inhibited by soluble laminin and by anti-laminin antibodies. Peptide G, an eicosapeptide derived from the complementary DNA sequence of the 67 LR precursor (IPCNNKGAHSVGLMWWMLAR) that specifically binds to laminin and presumably contains the active ligand-binding site of the receptor, specifically prevented attachment of the melanoma cells to both the bovine aortic endothelial cell monolayer and human umbilical vein endothelium. Thus, peptide G may selectively interfere with the metastatic cascade by inhibiting tumor cell attachment to endothelium via the laminin-67 LR pathway and is a potential new antimetastatic agent. [less ▲]

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See detailLaminin Receptors and Laminin-Binding Proteins During Tumor Invasion and Metastasis
Castronovo, Vincenzo ULg

in Invasion & Metastasis (1993), 13(1), 1-30

Interactions between cancer cells and laminin, a major component of basement membranes, play a critical role at several steps of the complex process of tumor invasion and metastasis. These interactions ... [more ▼]

Interactions between cancer cells and laminin, a major component of basement membranes, play a critical role at several steps of the complex process of tumor invasion and metastasis. These interactions are mediated through a large variety of cell surface proteins designated as laminin receptors and/or laminin-binding proteins. The growing number of identified laminin binding proteins and domains of this glycoprotein that are biologically active illustrate the complexity of cellular interactions with laminin. The 67-kD laminin receptor (67 LR) was the first protein identified in 1983 as a high-affinity laminin receptor, and its expression is dramatically increased in a large variety of cancer cells. The 67 LR is the subject of several controversies and confusion generated mainly by two events. First, the identification of several new laminin-binding proteins has raised the difficult task of attributing specific functions to specific receptors in contrast to initial beliefs that all cellular laminin-driven biological activities were mediated through the 67 LR. The second source of controversy is the large molecular-weight discrepancy between the 37-kD polypeptide encoded by the 67 LR cDNA clone and the mature 67 LR. In this manuscript, a critical and extensive review of the data accumulated on the 67 LR is presented regarding both its molecular structure and its role during tumor invasion and metastasis. A hypothetical model of the 67 LR is also proposed. Since the first identification of the 67 LR, at least 14 other cell surface molecules have been reported to be potential laminin receptors or laminin-binding proteins. These include members of the beta-galactoside-binding lectin family, seven members of the integrin family, the galactosyltransferase and some not yet fully characterized cell surface molecules. These laminin receptors and laminin-binding proteins are also described and their functions are also discussed with a particular emphasis on their participation in the constitution of the invasive phenotype. [less ▲]

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See detailLaminin--a glycoprotein from basement membranes.
Timpl, R.; Rhode, H.; Robey, P. G. et al

in Journal of Biological Chemistry (1979), 254(19), 9933-7

We have isolated a large noncollagenous glycoprotein, laminin, from a mouse tumor that produces basement membrane. The protein consists of at least two polypeptide chains (Mr = 220,000 and Mr = 440,000 ... [more ▼]

We have isolated a large noncollagenous glycoprotein, laminin, from a mouse tumor that produces basement membrane. The protein consists of at least two polypeptide chains (Mr = 220,000 and Mr = 440,000) joined to each other by disulfide bonds. Laminin and type IV collagen are major constituents of the tumor. Laminin is distinctly different from fibronectin, another component of basement membranes, in amino acid composition and immunological reactivity. Pepsin digestion of laminin releases a large, cystine-rich fragment which retains most of the antigenicity of the original protein. Immunological studies using purified antibody against laminin show that it is produced by a variety of cultured cells. In addition, these antibodies react with the basement membranes of normal tissues, suggesting that this protein or an immunologically related protein is a constituent of the basement membranes of these tissues. [less ▲]

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See detailLa lamotrigine (Lamictal).
Scheen, André ULg

in Revue Médicale de Liège (1997), 52(11), 738-40

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See detailLAN Switch Security: What Hackers Know About Your Switches
Vyncke, Eric ULg; Paggen, Christophe

Book published by CiscoPress (2006)

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See detailLancement d’un programme d’amélioration génétique de Jatropha curcas L. au Sénégal
Terren, Marieke ULg; Saverys, S.; Jacquet de Haverskercke, P et al

Poster (2009)

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See detailLand availability and housing development: the case of Wallonia
Halleux, Jean-Marie ULg; Strée, Julie ULg

Conference (2013, May 24)

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See detailLand conversion for industrialization and its impacts on household livelihood strategies in Hung Yen province, northern Vietnam
Nguyen, Thi Dien ULg

Doctoral thesis (2011)

This thesis is about the impact of land conversion for industrialization on household livelihood strategies in Hung Yen province, northern Vietnam. The study shows that land conversion is generating a ... [more ▼]

This thesis is about the impact of land conversion for industrialization on household livelihood strategies in Hung Yen province, northern Vietnam. The study shows that land conversion is generating a household landholdings decline while boosting the land market. After land conversion, 16% of laborers in the surveyed households find employment in industrial factories while 52% find jobs in the informal sector. Because of land conversion, rather than being net food producers, peasant households have become net food purchasers. Meantime, food safety in industrial areas is threatened by increasing environmental pollution. The findings also demonstrate that 51.9% of the surveyed households choose diversification as a livelihood strategy while 35.6% of them shift entirely to non-farm strategies. Among the affected peasant groups, households with a non-farm background that lost less than 50% of their agricultural land are likely to be in a better position to engage in lucrative non-farm jobs. Land conversion is causing a complex agrarian transformation in Vietnam. On the one hand, it generates a mechanism of social differentiation which is determined by land alteration and capital accumulation from high earning non-farm activities. On the other hand, peasant livelihood strategies, thanks to adaptation and innovation, have mitigated the impacts of land conversion and reveal the persistence of a peasant economy. [less ▲]

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See detailLand conversion to industrialization and its impacts on household food security in Red River Delta, Vietnam
Nguyen Thi, Dien; Lebailly, Philippe ULg; Vu Dinh, Ton

Conference (2010)

Since 1990s Vietnam is undergoing rapid industrialization with the national goal of becoming an industrial country. As a result, large tracts of agricultural land were conversed to industrial zones and ... [more ▼]

Since 1990s Vietnam is undergoing rapid industrialization with the national goal of becoming an industrial country. As a result, large tracts of agricultural land were conversed to industrial zones and clusters. This paper analyzes the complex impacts caused by industrialization on household food security. Both qualitative and quantitative methods were applied to investigate how land conversion process to industrial companies affected food security of different groups of peasant households in Hung Yen province, the most rapid industrialization province in Red River Delta of Vietnam. The study showed that industrialization and neo-liberalism affected household food security in three aspects: the lost of large agricultural land area which did not ensure stable jobs for peasants; the decline of living quality as a result of environmental pollution and high living costs; and the lost of household self reliance on food, with 77 percent of surveyed households not producing enough food for their own consumption. Industrialization had created a new class structure in the Vietnamese countryside with the rise of landless peasants who survived by selling their labor and who are net food buyers. The study contributes to the research that link the analysis of household food security with livelihood systems in the processes interacting across scales, from the very local to the global. [less ▲]

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See detailLand Cover Dynamics (1990-2002) in Binh Thuan Province, Southern Central Vietnam
Hountondji, Yvon ULg; De Longueville, Florence ULg; Ozer, Pierre ULg

in International Journal of Asian Social Science (2012), 2(3), 336-349

This paper describes the use of satellite imageries and GIS data for identifying key environmental characteristics of Binh Thuan Province in south central Vietnam and for detecting the major changes ... [more ▼]

This paper describes the use of satellite imageries and GIS data for identifying key environmental characteristics of Binh Thuan Province in south central Vietnam and for detecting the major changes patterns within this region. Landsat TM (1990) and Landsat ETM+ (2002) imageries were used to classify the study area into seven land use and land cover (LULC) classes. A post-classification comparison analysis was used to quantify and illustrate the various LULC conversions that took place over the 12-year span of time. Results showed that a steady growth in population has caused extensive changes of land cover throughout the area. The maps also indicate that the loss of woody land (forest) and the extension of wetlands (irrigated area), combined with built-up encroachment, remains one of the most serious environmental problems facing the Binh Thuan Province today. The post-classification change detection analysis showed that critical habitats accounted for nearly 38.5% of the intensive study area between 1990 and 2002 while 61.5% remained stable. Results also showed over the 12-year span, approximately 1151.2 km² (115.120 ha) forest were converted respectively to brush, irrigated area (wetlands), cropland and built-up. This is an overall average decrease of 9594 hectares of forested area per year. Throughout the study area, districts most affected by forest conversion to another land cover are: Bac Bihn (2798 ha/year), Than Linh (2717 ha/year), Ham Thuan Nam (1601 ha/year) and Ham Thuan Bac (1524 ha/year). Based on the identified causes of these changes, we made policy recommendations for better management of land use and land cover. [less ▲]

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See detailDas „Land der Väter“ im politischen Zionismus Theodor Herzls
Pontzen, Alexandra ULg

in Pontzen, Alexandra; Stähler, Axel (Eds.) Das Gelobte Land: Erez Israel von der Antike bis zur Gegenwart in Quellen und Darstellungen (2003)

Detailed reference viewed: 15 (3 ULg)
See detailDas Land der vielen Grenzen. Räume, Landschaft, Menschen
Brüll, Christoph ULg; Dries, Joseph; Quadflieg, Peter M.

in Lejeune, Carlo; Brüll, Christoph (Eds.) Grenzerfahrungen. Eine Geschichte der Deutschsprachigen Gemeinschaft Belgiens. Vol. 5: Säuberung, Wiederaufbau, Autonomiediskussionen (1945-1973) (2014)

„Landschaften, Räume sind nicht bloß vorhandene Realitäten, sondern auch und vor allem Überbleibsel der Vergangenheit. Vergangene Horizonte werden für uns neu gemalt, neu geschaffen durch die gebotenen ... [more ▼]

„Landschaften, Räume sind nicht bloß vorhandene Realitäten, sondern auch und vor allem Überbleibsel der Vergangenheit. Vergangene Horizonte werden für uns neu gemalt, neu geschaffen durch die gebotenen Spektakel: Die Erde ist, wie unsere Haut, dazu verdammt, die Spuren unserer alten Verletzungen zu bewahren.“ Diese Aussage des französischen Historikers Fernand Braudel ruft dazu auf, Landschaften und Räume zu lesen und zu interpretieren. Dies wollen wir als quasi institutionalisierten Einstieg in allen Bänden tun. Die Deutschsprachige Gemeinschaft – aktuell auf der Suche nach einem griffigeren Namen – ist ein zeitgenössisches Kunstgebilde. Diese Grenzlandschaft zwischen Maas und Rhein, zwischen deutschem und französischem Kulturraum sollte in jeder Zeit geografisch anders gefasst und in ihrer Wechselwirkung zu den Nachbarregionen dargestellt werden. In diesem Einstiegskapitel gilt es deshalb, die Region zunächst einfach geografisch zu umschreiben. Christoph Brüll, Joseph Dries und Peter M. Quadflieg haben dann gefragt: Was lässt sich an der Landschaft zwischen Göhl und Our für den Zeitraum von 1945 bis 1973 ablesen? Welche alten Verletzungen können wir beobachten? Welche zukunftsweisenden Entwicklungen lassen sich an der Landschaft bereits ablesen? [less ▲]

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See detailLand Management for Urban Dynamics
Golay, F.; Halleux, Jean-Marie ULg

Conference given outside the academic context (2007)

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See detailLand Managment for Urban Dynamics. Innovative tools and practices in a changing Europe
Tira, M.; van der Krabben, E.; Zanon, B. et al

Book published by Maggioli Editore (2011)

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See detailLand rights as an engine of growth ? An analysis of Cambodian landgrabs in the context of development theory
Rudi, Lisa-Marie; Azadi, Hossein; Witlox, Frank et al

in Land Use Policy (2014), (38), 564-572

Forceful evictions have become a serious problem in Cambodia with an increasing number of fami-lies being deprived of their land, homes and livelihoods without compensation. This article analysesCambodian ... [more ▼]

Forceful evictions have become a serious problem in Cambodia with an increasing number of fami-lies being deprived of their land, homes and livelihoods without compensation. This article analysesCambodian land rights in the context of economic development theory. It assesses whether increas-ing economic inequalities, stemming from forceful evictions, can be categorized as an impediment toCambodian economic growth. The Cambodian case illustrates that a lack of good governance due tocorruption leads to the unequal distribution of land which, in turn, causes inequitable economic devel-opment. The paper concludes that Cambodia is trapped in a vicious cycle of inequality, which is upheld byelites who benefit from evictions and land concessions while evictees become trapped in poverty. Giventhat the population is growing angrier, the article warns of potential for a violent revolution that couldhave disastrous consequences for the Cambodian kingdom, a country that recently emerged from yearsof civil conflicts and is still in the process of rebuilding its social fabric. [less ▲]

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See detailLand Subsidence in Shanghai (P.R. CHINA)
Baeteman, Cécile; Dassargues, Alain ULg; Schroeder, Christian ULg et al

in Proc. of XIII Int. Conf. of the Int. U. for Quater. Res (1991)

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See detailLand subsidence in Shanghai: hydrogeological conditions and subsidence measurements
Dassargues, Alain ULg; Zhang, J.

in Bulletin of Engineering Geology & the Environment (1992), 46

Detailed reference viewed: 36 (6 ULg)