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See detailA herpesvirus alters the behavior of its host to enhance its replication
Ronsmans, Maygane ULg

Conference (2015, December 18)

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See detailL’herpèsvirus B du singe, un agent d’anthropozoonose méconnu
Meurens, F.; Gallego, P.; Bourgot, I. et al

in Annales de Médecine Vétérinaire (2002), 146(1, FEB-MAR), 1-8

B-virus or Cercopithecine herpesvirus 1 (CeHV-1) is a zoonotic alphaherpesvirus enzootic in Asian monkeys of the genus Macaca that is genetically and antigenically closely related to the human herpesvirus ... [more ▼]

B-virus or Cercopithecine herpesvirus 1 (CeHV-1) is a zoonotic alphaherpesvirus enzootic in Asian monkeys of the genus Macaca that is genetically and antigenically closely related to the human herpesvirus 1 and the human herpesvirus 2. CeHV-1 infection is highly prevalent (80% to 100%) in adult macaques and may lead to fulminant encephalomyelitis with severe aftereffects or even causing death in humans. Since its discovery in 1933, it has been positively linked with two dozen human deaths. B-virus disease in humans usually resulted from breach of primary skin or mucosal defenses and subsequent contamination of the site with virus. Timely antiviral intervention is a good mean of reducing CeHV-1 associated morbidity and preventing a fatal outcome. [less ▲]

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See detailL’herpèsvirus bovin 4
Markine-Goriaynoff, N.; Minner, F.; De Fays, K. et al

in Annales de Médecine Vétérinaire (2003), 147(4), 215-247

Bovine herpesvirus 4 (BoHV-4) belongs to the Herpesviridae family, Gammaherpesvirinae subfamily, Rhadinovirus genus like human herpesvirus 8 (HHV-8), the causative agent of Kaposi's sarcoma. BoHV-4 has a ... [more ▼]

Bovine herpesvirus 4 (BoHV-4) belongs to the Herpesviridae family, Gammaherpesvirinae subfamily, Rhadinovirus genus like human herpesvirus 8 (HHV-8), the causative agent of Kaposi's sarcoma. BoHV-4 has a worldwide distribution in the cattle population. It has been isolated from cattle showing various clinical signs as well as from healthy cattle. The interest of the scientific community for BoHV-4 is explained by two reasons. Firstly, BoHV-4 represents an homologous virus/host species model to study the biology of gammaherpesviruses. Secondly, the use of BoHV-4 as a recombinant vector for expression both in vitro and in vivo has been proposed. For these reasons, a considerable amount of data has been collected on this virus. In the present paper, the authors will present a general overview of the literature published on this virus addressing clinical, epidemiological and fundamental aspects of BoHV-4. Finally, in the light of their recent phylogenetic data, the authors will discuss the origin and the host species of BoHV-4 leading to the conclusion that this virus should be considered as a virus of the African buffalo rather than cattle. [less ▲]

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See detailL'herpèsvirus bovin de type 4 : virus pathogène ou passager?
Thiry, Etienne ULg; Markine-Goriaynoff, Nicolas; Minner, Frédéric et al

in Point Vétérinaire (2000), 31

Bovine herpesvirus type 4 (BHV-4) is a ubiquitous herpesvirus in cattle. It has been isolated from animals showing a wide variety of clinical signs but few of the isolates have proven experimental ... [more ▼]

Bovine herpesvirus type 4 (BHV-4) is a ubiquitous herpesvirus in cattle. It has been isolated from animals showing a wide variety of clinical signs but few of the isolates have proven experimental pathogenicity. Species that are susceptible to BHV-4 include animals other than ruminants, notably cats and, surprisingly, a primate the owl monkey (Aotus trivirgatus). BHV-4 exists as a latent infection in mononuclear cells. In cattle, BHV-4 has been isolated in animals exhibiting ocular and respiratory conditions and it has been found in females with genital tract conditions such as post-partum metritis and vulvovaginitis. There is some epidemiological and experimental evidence that BHV-4 may be a cause of bovine abortion. There is no vaccine available in Europe and prevention is exclusively by hygiene measures. [less ▲]

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See detailLes herpèsvirus bovins : biologie et implications
Pastoret, Paul-Pierre ULg; Lemaire, Mylène; Denis, Martine et al

Part of book (1994)

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See detailEl herpesvirus caprino es altamente prevalente
Thiry, Julien ULg; Thiry, Etienne ULg

in Mundo Ganadero (2008), 214

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See detailHerpèsvirus des ruminants
Thiry, Etienne ULg

in Lefèvre, P. C.; Blancou, Jean; Chermette, R. (Eds.) Principales maladies infectieuses et parasitaires du bétail, Europe et régions chaudes, généralités, maladies virales (2003)

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See detailL'herpèsvirus félin 1, l'agent de la rhinotrachéite virale féline
Costes, Bérénice ULg; Van den Branden, A.; Thiry, Etienne ULg et al

in Annales de Médecine Vétérinaire (2007), 151

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See detailHerpesvirus in infertile bull's testicle
Thiry, Etienne ULg; Pastoret, Paul-Pierre ULg; Dessy, Cécile ULg et al

in Veterinary Record : Journal of the British Veterinary Association (1981), 108(19), 426

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See detailHerpesvirus infections in Cervidae
Nettleton, P. F.; Thiry, Etienne ULg; Reid, H. et al

in Revue Scientifique et Technique (International Office of Epizootics) (1988), 7

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See detailHerpesvirus infections of red deer andother wild ruminants in France and Belgium
Thiry, Etienne ULg; Pastoret, Paul-Pierre ULg; Barrat, J. et al

in Reid, H. (Ed.) The management and health of farmed deer (1988)

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See detailHerpesvirus Of Turkeys Homologue Of Hsv Vp16 Is Structurally Related To Varicella Zoster Virus Trans-Inducing Protein Encoded By Orf 10
Kopacek, J.; Zelnik, V.; Brasseur, Robert ULg et al

in Virus Genes (1997), 15(1), 45-52

Expression of the immediate-early genes of alpha-herpesviruses is stimulated by a family of trans-inducing factors represented by VP16 of HSV-1 and ORF10 gene product of VZV. We have identified and ... [more ▼]

Expression of the immediate-early genes of alpha-herpesviruses is stimulated by a family of trans-inducing factors represented by VP16 of HSV-1 and ORF10 gene product of VZV. We have identified and determined the nucleotide sequence of the UL48 gene encoding the herpesvirus of turkeys (HVT) homologue of HSV VP16. The gene maps to the BamHI-J fragment and appears to be expressed in a form of bicistronic transcript together with UL49. The deduced amino acid sequence of the protein encoded by HVT UL48 gene shows 55% identity with MDV UL48 gene product. Like the majority of related proteins in other alpha-herpesviruses, the protein encoded by HVT UL48 gene lacks the acidic C-terminal tail, known to possess the transactivation capacity of HSV VP16. Hydrophobic cluster analysis has revealed that its predicted domain composition is closely related to the transactivator protein encoded by ORF10 of VZV. However, the putative amino-terminal activation domain of the HVT homologue of HSV VP16 does not contain a typical horseshoe-like hydrophobic cluster found in other alpha-herpesvirus homologues, suggesting either that it acts as a transactivator via a different activation domain or that its transactivation potential is diminished. [less ▲]

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See detailHerpesviruses in respiratory liquids of horses : putative implication in airway inflammation and association with cytological features
Fortier, Guillaume ULg; Van Erck, Emmanuelle ULg; Fortier, Christine et al

in Veterinary Microbiology (2009), 139

The objectives of this study were to estimate the prevalence and the potential role of equine herpesviruses (EHVs) detection in both bronchoalveolar lavage (BAL) and tracheal wash (TW). The population ... [more ▼]

The objectives of this study were to estimate the prevalence and the potential role of equine herpesviruses (EHVs) detection in both bronchoalveolar lavage (BAL) and tracheal wash (TW). The population included a control group (CTL; 37 TW and 25 BAL) and a pathological group (PAT; 259 TW and 387 BAL), including horses either suffering from respiratory diseases including syndrome of tracheal inflammation, inflammatory airway disease, recurrent airway obstruction, or submitted to respiratory investigation because of exercise intolerance or poor performance. Each respiratory liquid was submitted to a standardised cytological analysis, mentioning the morphological abnormalities of exfoliated epithelial cells (ECAb) and ciliocytophthoria (CCPh) as markers of potential viral infection, as well as PCR assays including a consensus PCR and virus-specific PCR for both equine alphaherpesviruses (EHV-1; EHV-4) and gammaherpesviruses (EHV-2; EHV-5). The EHV infections were more prevalent in the TW of PAT group (P = 0.004), with the highest prevalence being for EHV-2 (P = 0.006). The EHV detection in BALs was not significantly different between groups. The EHVs detection in TW was correlated to the polymorphonuclear neutrophil (PMN) counts in the respiratory liquid but not with CCPh or ECAb. CCPh or ECAb were associated with both consensus PCR and EHV-2 and EHV-5 virus-type PCR in the BAL only. The significant detection of EHVs in the TWof PAT group in association with the PMN increased counts could lead to further investigations about their putative role in equine syndrome of tracheal inflammation [less ▲]

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See detailL'herpétofaune des bords de route en Wallonie: analyse de 101 stations
Graitson, Eric ULg

in Naturalistes Belges (Les) (2006), 87(3), 73-80

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See detail"Der Herr Etatsrat", eine Monsternovelle
Gerrekens, Louis ULg

in Schriften der Theodor-Storm-Gesellschaft (2012)

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See detailHerschel discovery of a new class of cold, faint debris discs
Eiroa, C.; Marshall, J. P.; Mora, A. et al

in Astronomy and Astrophysics (2011), 536

We present Herschel PACS 100 and 160 μm observations of the solar-type stars α Men, HD 88230 and HD 210277, which form part of the FGK stars sample of the Herschel open time key programme (OTKP) DUNES ... [more ▼]

We present Herschel PACS 100 and 160 μm observations of the solar-type stars α Men, HD 88230 and HD 210277, which form part of the FGK stars sample of the Herschel open time key programme (OTKP) DUNES (DUst around NEarby Stars). Our observations show small infrared excesses at 160 μm for all three stars. HD 210277 also shows a small excess at 100 μm, while the 100 μm fluxes of α Men and HD 88230 agree with the stellar photospheric predictions. We attribute these infrared excesses to a new class of cold, faint debris discs. Both α Men and HD 88230 are spatially resolved in the PACS 160 μm images, while HD 210277 is point-like at that wavelength. The projected linear sizes of the extended emission lie in the range from ~115 to ≤ 250 AU. The estimated black body temperatures from the 100 and 160 μm fluxes are ≲22 K, and the fractional luminosity of the cold dust is L[SUB]dust[/SUB]/L[SUB] ⋆ [/SUB] ~ 10[SUP]-6[/SUP], close to the luminosity of the solar-system's Kuiper belt. These debris discs are the coldest and faintest discs discovered so far around mature stars, so they cannot be explained easily invoking "classical" debris disc models. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA. [less ▲]

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See detailHerschel imaging and spectroscopy of the nebula around the luminous blue variable star WRAY 15-751
Vamvatira-Nakou, Chloi ULg; Hutsemekers, Damien ULg; Royer, P. et al

in Astronomy and Astrophysics (2013), 557

We have obtained far-infrared Herschel-PACS imaging and spectroscopic observations of the nebular environment of the luminous blue variable (LBV) WRAY 15-751. The far-infrared images clearly show that the ... [more ▼]

We have obtained far-infrared Herschel-PACS imaging and spectroscopic observations of the nebular environment of the luminous blue variable (LBV) WRAY 15-751. The far-infrared images clearly show that the main, dusty nebula is a shell of radius 0.5 pc and width 0.35 pc extending outside the Hα nebula. Furthermore, these images reveal a second, bigger and fainter dust nebula that is observed for the first time. Both nebulae lie in an empty cavity, very likely the remnant of the O-star wind bubble formed when the star was on the main sequence. The kinematic ages of the nebulae are calculated to be about 2 × 10^4 and 8 × 10^4 years, and we estimated that each nebula contains ~0.05 Msun of dust. Modeling of the inner nebula indicates a Fe-rich dust. The far-infrared spectrum of the main nebula revealed forbidden emission lines coming from ionized and neutral gas. Our study shows that the main nebula consists of a shell of ionized gas surrounded by a thin photodissociation region illuminated by an “average” early-B star. We derive the abundance ratios N/O = 1.0 ± 0.4 and C/O = 0.4 ± 0.2, which indicate a mild N/O enrichment. From both the ionized and neutral gas components we estimate that the inner shell contains 1.7 ± 0.6 Msun of gas. Assuming a similar dust-to-gas ratio for the outer nebula, the total mass ejected by WRAY 15-751 amounts to 4± 2 Msun. The measured abundances, masses and kinematic ages of the nebulae were used to constrain the evolution of the star and the epoch at which the nebulae were ejected. Our results point to an ejection of the nebulae during the red super-giant (RSG) evolutionary phase of an ~40 Msun star. The multiple shells around the star suggest that the mass-loss was not a continuous ejection but rather a series of episodes of extreme mass-loss. Our measurements are compatible with the recent evolutionary tracks computed for an ~40 Msun star with little rotation. They support the O–BSG–RSG–YSG–LBV filiation and the idea that high-luminosity and low-luminosity LBVs follow different evolutionary paths. [less ▲]

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