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See detailHomogenization techniques in electromagnetics
Vazquez Sabariego, Ruth ULg

Scientific conference (2011, August)

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See detailHomogenization techniques in low frequency electromagnetics
Vazquez Sabariego, Ruth ULg

Scientific conference (2011, January 03)

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See detailHomogenization techniques in low frequency problems
V Sabariego, Ruth ULg

Scientific conference (2008, March)

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See detailHomogenization with propagation of instabilities through the different scales
Noels, Ludovic ULg; Wu, Ling ULg; Nguyen, Van Dung ULg et al

Scientific conference (2014, January 31)

In this work, multi-scale methods with strain softening are developed in the contexts of damage modeling for composite laminates and of buckling analyses in cellular materials. First, an anisotropic ... [more ▼]

In this work, multi-scale methods with strain softening are developed in the contexts of damage modeling for composite laminates and of buckling analyses in cellular materials. First, an anisotropic gradient–enhanced continuum damage model is embedded in a mean–field homogenization (MFH) process for elasto-plastic composites. The homogenization procedure is based on the newly developed incremental secant mean-field homogenization formulation, for which the residual stress and strain states reached in the phases upon a fictitious elastic unloading are considered as starting point to apply the secant method. The mean stress fields in the phases are then computed using isotropic secant tensors, which are naturally used to define the Linear Comparison–Composite The resulting multi– scale model is then applied to study the damage process at the meso–scale of laminates, and in particular the damaging of plies in a composite stack. By using the gradient–enhanced continuum damage model, the problem of losing uniqueness upon strain softening is avoided. Second, an efficient multi–scale finite element framework capturing the buckling instabilities in cellular materials is developed. As a classical multi–scale computational homogenization scheme loses accuracy with the apparition of the macroscopic localizations resulting from the micro–buckling, the second order multi–scale computational homogenization scheme is considered. This second–order computational framework is enhanced with the following novelties so that it can be used for cellular materials. At the microscopic scale, the periodic boundary condition is used because of its efficiency. As the meshes generated from cellular materials exhibit a large void part on the boundaries and are not conforming in general, the classical enforcement based on the matching nodes cannot be applied. A new method based on the polynomial interpolation2 without the requirement of the matching mesh condition on opposite boundaries of the representative volume element (RVE) is developed. Next, in order to solve the underlying macroscopic Mindlin strain gradient continuum of this second–order scheme by the displacement–based finite element framework, the treatment of high order terms is based on the discontinuous Galerkin (DG) method to weakly impose the C1-continuity. Finally, as the instability phenomena are considered at both scales of the cellular materials, the path following technique is adopted to solve both the macroscopic and microscopic problems. [less ▲]

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See detailHomogenizing clinical training through ‘à la carte’ self-directed learning
Maillart, Christelle ULg; Grevesse, Pascale; Wiot, Nathalie

Poster (2012, May 25)

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See detailHomoleptic Diphosphacyclobutadiene Complexes [M(4-P2C2R2)2]x- (M=Fe, Co; x=0, 1),
Wolf, Robert; Ehlers, Andreas W; Khusniyarov, Marat M et al

in Chemistry : A European Journal (2010), 16

The preparation and comprehensive characterization of a series of homoleptic sandwich complexes containing diphosphacyclobutadiene ligands is reported. Compounds [K([18]crown-6)(thf)2][Fe(h4- P2C2tBu2)2 ... [more ▼]

The preparation and comprehensive characterization of a series of homoleptic sandwich complexes containing diphosphacyclobutadiene ligands is reported. Compounds [K([18]crown-6)(thf)2][Fe(h4- P2C2tBu2)2] (K1), [K([18]crown-6)-(thf)2][Co(h4-P2C2tBu2)2] (K2), and [K([18]crown-6)(thf)2][Co(h4- P2C2Ad2)2] (K3, Ad=adamantyl) were obtained from reactions of [K([18]crown-6)(thf)2][M(h4-C14H10)2] (M=Fe, Co) with tBuC P (1, 2), or with AdC P (3). Neutral sandwiches [M(h4-P2C2tBu2)2] (4: M=Fe 5: M= Co) were obtained by oxidizing 1 and 2 with [Cp2Fe]PF6. Cyclic voltammetry and spectro-electrochemistry indicates that the pairs [M(h4-P2C2tBu2)2] / [M(h4-P2C2tBu2)2] can be reversibly interconverted by one electron oxidation and reduction, respectively. Complexes 1–5 were characterized by multinuclear NMR, EPR (1 and 5), UV/Vis, and Mçssbauer spectroscopies (1 and 4), mass spectrometry (4 and 5), and microanalysis (1–3). The molecular structures of 1–5 were determined by usingX-ray crystallography. Essentially D2dsymmetric structures were found for all five complexes, which show the two 1,3-diphosphacyclobutadiene rings in a staggered orientation. Density functional theory calculations revealed the importance of covalent metal–ligand p bonding in 1–5. Possible oxidation state assignments for the metal atoms are discussed. [less ▲]

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See detailL'homologation judiciaire des conventions. Essai d'une théorie générale.
Moreau, Pierre ULg

Doctoral thesis (2007)

Lorsqu’il recourt à la technique de l’homologation en matière contractuelle, le législateur permet ou impose aux parties qu’aucun litige n’oppose (plus), de soumettre leur convention au contrôle d’un juge ... [more ▼]

Lorsqu’il recourt à la technique de l’homologation en matière contractuelle, le législateur permet ou impose aux parties qu’aucun litige n’oppose (plus), de soumettre leur convention au contrôle d’un juge. Bien que la décision que le juge rend à l’issue de ce contrôle soit susceptible de modifier le rapport contractuel de base, le législateur n’a pas défini le régime et les effets de l’homologation. L’auteur tente de mettre au jour le corps des règles communes aux différentes homologations de contrats et de préciser, eu égard à ces règles, l’incidence de l’intervention judiciaire sur les relations des parties entre elles et vis-à-vis des tiers. Dans la première partie de l’étude, est développé le contexte dans lequel s’inscrit l’homologation judiciaire des conventions. Cette partie est axée sur les deux aspects que comporte ce contexte; le premier titre est consacré au rôle du juge face au litige et le second au rôle du juge face au contrat. La seconde partie de l’étude contient les développements propres à la théorie de l’homologation judiciaire des conventions. Pour construire cette théorie, l’auteur est amené à conjuguer la nature contractuelle de la convention soumise à homologation et la nature judiciaire de cette dernière. En définitive, il s’agit de répondre à la question qui sous-tend le concept : l’homologation transmue-t-elle la convention qui lui est soumise ? Par l’élaboration de la théorie générale, l’auteur a cherché à faciliter la tâche des magistrats appelés, dans nombre d’hypothèses, à homologuer des conventions, comme à éclairer les praticiens, sur les effets de l’homologation judiciaire des conventions. [less ▲]

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See detailHomologies entre les deux retrovirus BLV et HTLV-1 et developpement d'une nouvelle approche therapeutique basee sur la levee de la latence virale.
Gillet, Nicolas ULg; Kettmann, Richard ULg; Willems, Luc ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(2),

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See detailHomologies to plastid DNA in the nuclear and mitochondrial genomes of potato.
Du Jardin, Patrick ULg

in Theoretical and Applied Genetics (1990), 79(6),

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See detailHomologous and hybrid calcium complexes of A23187 and hypoglycemic sulfonylureas: nuclear magnetic resonance and conformational analysis.
Deleers, M.; Brasseur, Robert ULg; Gelbcke, M. et al

in Journal of Inorganic Biochemistry (1982), 16(3), 215-25

Hypoglycemic sulfonylureas (e.g., gliclazide) are able to transport calcium across hydrophobic domains. Gliclazide and the ionophore A23187 act synergistically upon calcium transport. One calcium atom is ... [more ▼]

Hypoglycemic sulfonylureas (e.g., gliclazide) are able to transport calcium across hydrophobic domains. Gliclazide and the ionophore A23187 act synergistically upon calcium transport. One calcium atom is complexed by either two molecules of sulfonylureas (or A23187) or one molecule each of sulfonylurea and A23187; the existence of such hybrid complexes has been documented by nuclear magnetic resonance. Conformation analysis of the calcium-gliclazide complex suggests close apposition of the toluyl groups in the gliclazide molecules. [less ▲]

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See detailHomologous radioimmunoassay for bovine insulin-like growth factor-binding protein-2 (IGFBP-2)
Portetelle, Daniel ULg; Vleurick, Live; Massart, Serge et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1998), 2(special issue), 13

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See detailHomologous radioimmunoassay for bovine insulin-like growth factor-binding protein-2 (IGFBP-2).
Vleurick, Lieve; Portetelle, Daniel ULg; Massart, Serge et al

in 3° Internat. Conf. farm Anim. Endocrinol. (1998)

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See detailA homologous radioimmunoassay for canine prolactin: plasma levels during the reproductive cycle
De Coster, R.; Beckers, Jean-François ULg; Beerens, D. et al

in Acta Endocrinologica (1983), 103

A method is described for the purification of canine prolactin, involving preparative isoelectrofocusing. Canine prolactin has a molecular weight of 23 000 daltons, an isoelectric point of 5.7 and ... [more ▼]

A method is described for the purification of canine prolactin, involving preparative isoelectrofocusing. Canine prolactin has a molecular weight of 23 000 daltons, an isoelectric point of 5.7 and exhibits a high degree of homogeneity in polyacrylamide gels stained by means of a silver method. A specific, homologous radioimmunoassay is described using the Bolton-Hunter method for preparation of the labelled ligand, with a sensitivity of 1.1 ng/tube. Basal plasma prolactin levels of 2-4 ng/ml obtained through the oestrous cycle remained fairly constant but a rise of 9 ng/ml was found at the end of disoetrus in nonpregnant bitches. Level also rose 30 days after mating to reach a peak of about 50 ng/ml near parturition and during early lactation. [less ▲]

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See detailA homologous radioimmunoassay for quantification of insulin-like growth factor-binding protein-2 in blood from cattle.
Vleurick, Lieve; Renaville, Robert ULg; VandeHaar, M. et al

in Journal of Dairy Science (2000), 83(3), 452-8

Insulin-like growth factor-I and -II (IGF-I, IGF-II) circulate in biological fluids bound to six different IGF-binding proteins that regulate IGF bioactivity. The IGF-binding protein-2 is regulated by ... [more ▼]

Insulin-like growth factor-I and -II (IGF-I, IGF-II) circulate in biological fluids bound to six different IGF-binding proteins that regulate IGF bioactivity. The IGF-binding protein-2 is regulated by growth hormones, and its concentration depends on nutrition and physiological state. Specific antibodies directed against bovine IGF-binding protein-2 were produced, and IGF-binding protein-2 levels in bovine blood samples were quantified by radioimmunoassay. Parallel displacement curves showed strong cross-reactivity with bovine and ovine plasma, were low with porcine plasma, and no cross-reactivity with rat or chicken plasma. Addition of IGF-I or -II to a control pool of bovine plasma did not significantly alter control IGF-binding protein-2 values in a radioimmunoassay. Six nycthemeral periods, determined for three young bulls bled on two occasions, showed that IGF-binding protein-2 plasma levels were stable throughout the day; two or three samples were sufficient to characterize the animal. Cows treated with recombinant bovine somatotropin (bST) had significantly lower serum levels of IGF-binding protein-2 than did control cows. Furthermore, IGF-binding protein-2 levels were dramatically increased at the onset of lactation. This radioimmunoassay for bovine IGF-binding protein-2, which enables quantitative assessment of IGF-binding protein-2 concentration in cattle, confirmed that IGF-binding protein-2 concentrations are depressed by administration of bST, enhanced after calving, and showed absence of diurnal variation. [less ▲]

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See detailA homologous radioimmunoassay for quantification of insulin-like growth factor-binding protein-3 in blood from cattle.
Renaville, Robert ULg; Bertozzi, Carlo; Hornick, J. L. et al

in Proceedings of the 2nd Belgian Workshop on Animal Endocrinology. (2000, November 15)

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See detailHomologous recombinant growth hormone and calcium metabolism in the tilapia oreochromis mossambicus, adapted to freshwater
Flik, G.; Atsma, W.; Fenwick, J. C. et al

in Journal of Experimental Biology (1993)

Homologous recombinant tilapia growth hormoe was tested for its effect on calcium metabolism in freshwater tilapia Oreochromis mossambicus. A comparison of the role of GH and prolactin in calcium ... [more ▼]

Homologous recombinant tilapia growth hormoe was tested for its effect on calcium metabolism in freshwater tilapia Oreochromis mossambicus. A comparison of the role of GH and prolactin in calcium regulation of the tilapia led to the conclusion that GH has specific calciopropic effects on freshwater Tilapia that differ from those of prolactin. [less ▲]

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See detailHomology and Cohomology Computation in Finite Element Modeling
Pellikka, M.; Suuriniemi, S.; Kettunen, L. et al

in SIAM Journal on Scientific Computing (2013), 35(5), 1195--1214

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See detailHomology modeling of MT(1) and MT(2) receptors
Farce, Amaury; Chugunov, Anton O.; Logé, Cédric et al

in European Journal of Medicinal Chemistry (2008), 43

Melatonin is a neurohormone synthesized and secreted mainly during the dark period of the circadian cycle by the pineal gland. It has already been proved to be involved in a number of chronobiological ... [more ▼]

Melatonin is a neurohormone synthesized and secreted mainly during the dark period of the circadian cycle by the pineal gland. It has already been proved to be involved in a number of chronobiological processes, most of them being mediated by its membranar receptors MT1 and MT2. Both are members of the GPCR class and, despite the interest they elicit, their 3D structure is still to be described. Models for both human MT1 and MT2 receptors have been constructed by homology modeling, using the X-ray structure of bovine rhodopsin as template. These models have been evaluated in terms of hydrophobic properties of the helices and refined to take into account the rearrangement of GPCRs necessary for their activation, thus leading to a putative activated model for each subtype. [less ▲]

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See detailHomology modeling of the serotoninergic 5-HT2c receptor
Farce, Amaury; Dilly, Sébastien ULg; Yous, Said et al

in Journal of Enzyme Inhibition and Medicinal Chemistry (2006), 21

Since its discovery, 5-hydroxytryptamine, more usually called serotonin, has been an elusive candidate as a major mood regulator. This capacity gives it a great importance in the treatment of depression ... [more ▼]

Since its discovery, 5-hydroxytryptamine, more usually called serotonin, has been an elusive candidate as a major mood regulator. This capacity gives it a great importance in the treatment of depression. It is within this framework that our work takes place, as it is related more particularly to a new therapeutic class whose leader is agomelatine. This compound binds to the melatoninergic receptors and to the serotoninergic 5-HT2c receptor, giving rise to the MASSA concept (Melatonin Agonist and Selective Serotonin Antagonist). Like the majority of the serotoninergic receptors, the sub-type 5-HT2c is a G-protein coupled receptor (GPCR). The three-dimensional structure of 5-HT2c is not experimentally known, and we thus resorted to comparative homology modelling to build a model allowing us to study its interactions with agomelatine. [less ▲]

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See detailThe Homolytic And Heterolytic Fatty Acid Hydroperoxide Lyase-Like Activities Of Hematin
Delcarte, J.; Jacques, Philippe ULg; Fauconnier, Marie-Laure ULg et al

in Biochemical and Biophysical Research Communications (2001), 286(1),

Pentenols and pentene dimers are biosynthetized in plants by homolytic fatty acid hydroperoxide lyase (HPL) or HPL-like enzymes. It has been found that these compounds can modify the flavor of olive oil ... [more ▼]

Pentenols and pentene dimers are biosynthetized in plants by homolytic fatty acid hydroperoxide lyase (HPL) or HPL-like enzymes. It has been found that these compounds can modify the flavor of olive oil. Reactions between hematin and 13-hydroperoxyoctadecatrienoic acid resulted in the formation of the same compounds via a free radical reaction in which an alkoxyl radical derived from linolenic acid hydroperoxide undergoes a β-scission. (Z)-3-Hexenal has also been detected as a minor product of the reaction. It is bioconversed from the same substrate in plants by heterolytic HPL. Thanks to the redox cycle of its central iron, hematin has both homolytic and heterolytic HPL-like activities. [less ▲]

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