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See detailIl killer malinconico
Emmanuel, François; Ricciardi, Stefania ULg

Book published by Carte Scoperte (2008)

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See detailKilling kinetics of clinical isolates of group B streptococci isolated in Belgium for penicillin alone or in combination with gentamicin
MELIN, Pierrette ULg; Lorquet, Sophie; HAYETTE, Marie-Pierre ULg et al

Poster (2005, September)

BACKGROUND: Associated with high morbidity and mortality, severe GBS infections should be treated with antimicrobial agents alone or in combination characterized by both a good diffusion at the site of ... [more ▼]

BACKGROUND: Associated with high morbidity and mortality, severe GBS infections should be treated with antimicrobial agents alone or in combination characterized by both a good diffusion at the site of infection and a short bactericidal lag time. Penicillin (P) or another blactam used in combination with an aminoglycoside is usually recommended to start the therapy. MICs to gentamicin (G) of GBS recently isolated in Belgium range from 16 to 256 mg/L (> or = MICs of E.faecalis with low level resistance to G, LLR). OBJECTIVES: To investigate in vitro, the potential synergism of P+G on strains of GBS isolated in Belgium. METHODS: According to Etest-AB Biodisk original procedures, for 6 Belgian strains of GBS (G MICs: 16-128 mg/L), we investigated the potential synergism, MICs and time killing curves, between P and G (ratio1:1). In the killing kinetic assays, surviving organisms were enumerated initially and repeatedly after 2, 4, 8 and 20 hours (T2, T4, T8 and T20) at concentrations of P equal to 4 and 16x MICs. Two strains of E.faecalis (1 HighLR and 1 LLR to G) were used as negative and positive control. Each isolate was tested twice. RESULTS: For GBS the P MICs in the combination were within +/- 1 dilution compared with single drug. As expected, P+G produced enhanced killing at T2 and T4 compared with P alone for G LLR E.faecalis and there was no difference for the G HLR E.faecalis. On the contrary, no accelerated killing was observed for any GBS isolate with the combination even for a concentration of 16xMIC of P; moreover for 3 isolates a reduced killing was observed at T2 in the combination tests compared with P alone. CONCLUSION: This limited in vitro testing of the combination P+G compared with P alone for Belgian GBS isolates did not show any synergism or accelerated killing. Moreover the killing was reduced at T2 for half of the isolates. Further evaluation should be performed on these strains with other ratio or other b-lactams as ampicillin in combination with G. [less ▲]

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See detailKilling Kinetics of Group B Streptococci for Penicillin in Combination with Gentamicin
Melin, Pierrette ULg; Lorquet, Sophie ULg; Hayette, Marie-Pierre ULg et al

in Sriprakash, Kabada S (Ed.) "Streptococci: New Insights into an Old Enemy", Proceedings of the XVI Lancefield International Symposium on Streptococci and Streptococcal Diseases (2006)

In vitro synergism and killing kinetics studies of penicillin in combination with gentamicin were performed with group B streptococci recently isolated in Belgium. The expected accelerated killing was not ... [more ▼]

In vitro synergism and killing kinetics studies of penicillin in combination with gentamicin were performed with group B streptococci recently isolated in Belgium. The expected accelerated killing was not observed when compared with penicillin alone. D 2005 Elsevier B.V. All rights reserved. [less ▲]

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See detailKimbangu
Melice, Anne ULg

in Poddar, Prem; Patke, Rajeev S.; Jensen, Lars (Eds.) A Historical Companion to Postcolonial Literatures. Continental Europe and its Empires (2008)

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See detailLe kimbanguisme : un millénarisme dynamique de la terre aux Cieux
Melice, Anne ULg

Scientific conference (2000, December 01)

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See detailLe kimbanguisme : un millénarisme dynamique de la terre aux Cieux
Melice, Anne ULg

in Bulletin des Séances de l’Académie Royale des Sciences d’Outre-Mer = Mededelingen der Zittingen van de Koninklijke Academie voor Overzeese Wetenschappen (2001), 47 (suppl.)

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See detailLe kimbanguisme : une "société" en mutation ?
Melice, Anne ULg

Conference (2001, December 13)

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See detailLe kimbanguisme aujourd’hui : une Église prophétique entre dispersion et centralité
Melice, Anne ULg

Scientific conference (2013, April 30)

Dans mon exposé, je rends compte des mouvements disruptifs ou de dispersion qui animent l’imaginaire, c’est-à-dire les croyances partagées, et les pratiques de l’Église kimbanguiste (EJCSK) depuis les ... [more ▼]

Dans mon exposé, je rends compte des mouvements disruptifs ou de dispersion qui animent l’imaginaire, c’est-à-dire les croyances partagées, et les pratiques de l’Église kimbanguiste (EJCSK) depuis les années 1990. Il s’agit : premièrement, du surgissement de figures charismatiques en marge de l’Église (les Milimo), deuxièmement, de l’apparition d’une hétérodoxie doctrinale, et, troisièmement, de la dissidence à l’œuvre dans l’Église depuis 2002. Je montre que l’Église s’emploie à contenir son risque d’éclatement en multipliant les opérations de recentrages théologiques, institutionnels et charismatiques, voire politiques et cela jusqu’au sein de sa diaspora. [less ▲]

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See detailLe kimbanguisme et le politique au Congo belge
Melice, Anne ULg

Conference given outside the academic context (2011)

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See detailLe kimbanguisme et le pouvoir en RDC : entre apolitisme et conception théologico-politique
Melice, Anne ULg

in Civilisations (2009), LVIII(2), 59-80

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See detailKindliches Kriegserleben als autobiografischer Gegenstand. Der Erste Weltkrieg in den Autobiografien von Sebastian Haffner, Jean-Paul Sartre und Hilde Spiel
Viehöver, Vera ULg

in Schmitz, Helmut; Preußer, Heinz-Peter (Eds.) Autobiografie und historische Krisenerfahrung (2010)

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See detailLa kiné de qualité en cinq ans à l'unif
Henrotin, Yves ULg

Article for general public (2004)

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See detailKinematic analysis of swimming ontogeny in seabass (Dicentrarchus labrax).
Olivier, Damien ULg; Vandewalle, Nicolas ULg; Parmentier, Eric ULg et al

in Belgian Journal of Zoology (2013)

Swimming has been investigated in multiple species, but few studies consider the establishment of swimming through ontogeny. This study describes the establishment of cyclical swimming in Dicentrachus ... [more ▼]

Swimming has been investigated in multiple species, but few studies consider the establishment of swimming through ontogeny. This study describes the establishment of cyclical swimming in Dicentrachus labrax, a marine fish from cold, temperate waters. The data were compared with results from previous studies on two subtropical freshwater catfish species (Clarias gariepinus and Corydoras aeneus). The three species have different modes of locomotion during their adult stage (anguilliform, subacarangiform and carangiform). The swimming of Dicentrarchus labrax was recorded with a high-speed video camera (500 fps) from 0 to 288 hours and from 960 to 2496 hours post-hatching. Three indices, i.e. coefficient of determination (r²), coefficient of variation (CV), and Strouhal number (St), were used to investigate the establishment and efficiency of swimming. Important differences in the timing of swimming establishment were observed between the seabass and the two catfish species. The two catfish species display a sine-shape swimming mode immediately or soon after hatching, and the efficiency of movement substantially improves during the first days of life. For seabass, however, establishment of swimming is slower during the same developmental period. These differences may be related to a faster developmental rate in the catfishes that allows them to swim rapidly in an intermediate regime flow and to develop the required morphology to establish efficient movements earlier. [less ▲]

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See detailA kinematic model for hysteretic dissipation of vibration energy for torsional damper and detuner.
Danilin, Alexander; Vinogradov, Alexander; Lilien, Jean-Louis ULg

in Lilien, Jean-Louis (Ed.) Proceedings of the 7th International Conference on Cable Dynamics (2007, December)

A description of the damping properties and model of a low frequency damper for power lines galloping.

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See detailKinematical Optimization of Closed-Loop Multibody Systems
Collard, Jean-François; Duysinx, Pierre ULg; Fisette, Paul

in Botasso, Carlo (Ed.) Multibody Dynamics - Computational Methods and Applications (2009)

Applying optimization techniques in the field of multibody systems (MBS) has become more and more attractive considering the increasing development of computer resources. One of the main issues in the ... [more ▼]

Applying optimization techniques in the field of multibody systems (MBS) has become more and more attractive considering the increasing development of computer resources. One of the main issues in the optimization of MBS concerns closed-loop systems which involve non-linear assembly constraints that must be solved before any analysis of the system. The addressed question is: how to optimize such closed-loop topologies when the objective evaluation relies on the assembly of the system? The authors have previously proposed to artificially penalize the objective function when those assembly constraints cannot be exactly fulfilled. However, the method suffers from some limitations especially due to the difficulty to get a differentiable objective function. Therefore, the key idea of this paper is to improve the penalty approach. Practically, instead of solving the assembly constraints, their norm is minimized and the residue is taken as a penalty term instead of an artificial value. Hence, the penalized objective function becomes differentiable throughout the design space, which enables the use of efficient gradient-based optimization methods such as the sequential quadratic programming (SQP) method. To illustrate the reliability and generality of the method, two applications are presented. They are related to the isotropy of parallel manipulators. The first optimization problem concerns a 3-dof Delta robot with 5 design parameters and the second one deals with a more complex 6-dof model of the Hunt platform involving 10 design variables. [less ▲]

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See detailKinematics-Based Macro Models for Deep Beams
Mihaylov, Boyan ULg

Scientific conference (2012, June 14)

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See detailKinetic and binding properties of the oxoglutarate translocator of rat-heart mitochondria.
Sluse, Francis ULg; Duyckaerts, Claire ULg; Sluse-Goffart, Claudine et al

in European Journal of Biochemistry (1979), 100

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See detailKinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 β-lactamases.
Delbrück, Heinrich; Bogaerts, Pierre; Kupper, Michaël et al

in Antimicrobial Agents and Chemotherapy (2012), 56(11)

GES-1 is a class A extended-spectrum β-lactamase conferring resistance to penicillins, narrow- and expanded-spectrum cephalosporins, and ceftazidime. However, GES-1 poorly hydrolyzes aztreonam and ... [more ▼]

GES-1 is a class A extended-spectrum β-lactamase conferring resistance to penicillins, narrow- and expanded-spectrum cephalosporins, and ceftazidime. However, GES-1 poorly hydrolyzes aztreonam and cephamycins and exhibits very low k(cat) values for carbapenems. Twenty-two GES variants have been discovered thus far, differing from each other by 1 to 3 amino acid substitutions that affect substrate specificity. GES-11 possesses a Gly243Ala substitution which seems to confer to this variant an increased activity against aztreonam and ceftazidime. GES-12 differs from GES-11 by a single Thr237Ala substitution, while GES-14 differs from GES-11 by the Gly170Ser mutation, which is known to confer increased carbapenemase activity. GES-11 and GES-12 were kinetically characterized and compared to GES-1 and GES-14. Purified GES-11 and GES-12 showed strong activities against most tested β-lactams, with the exception of temocillin, cefoxitin, and carbapenems. Both variants showed a significantly increased rate of hydrolysis of cefotaxime, ceftazidime, and aztreonam. On the other hand, GES-11 and GES-12 (and GES-14) variants all containing Ala243 exhibited increased susceptibility to classical inhibitors. The crystallographic structures of the GES-11 and GES-14 β-lactamases were solved. The overall structures of GES-11 and GES-14 are similar to that of GES-1. The Gly243Ala substitution caused only subtle local rearrangements, notably in the typical carbapenemase disulfide bond. The active sites of GES-14 and GES-11 are very similar, with the Gly170Ser substitution leading only to the formation of additional hydrogen bonds of the Ser residue with hydrolytic water and the Glu166 residue. [less ▲]

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