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See detailHemicolectomie droite par laparoscopic
COIMBRA MARQUES, Carla ULg

Conference (2013, November 21)

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See detailHéminégligence par lésion frontale droite: A propos de trois observations
Van der Linden, Martial ULg; Seron, X.; Gillet, J. et al

in Acta Neurologica Belgica (1980), 80

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See detailHemipteran - host plant interactions: focus on some model insect saliva
Serteyn, Laurent ULg; Moreau, Sophie; Delatour, Anaïs et al

Poster (2015, November)

Insect salivary components play important roles in plant-insect interactions, stimulating the plant defence or promoting infestation by manipulating plant physiology. Indeed, a variety of enzymes and ... [more ▼]

Insect salivary components play important roles in plant-insect interactions, stimulating the plant defence or promoting infestation by manipulating plant physiology. Indeed, a variety of enzymes and organic components in saliva of herbivory insects can induce series of biochemical responses in damaged plants. In our lab, several studies have been screening proteins in different aphid species saliva. The purpose of our current and future works is to widen that field of study to other piercing-sucking pests and host plants models. Three models will be compared: the pea aphid (Acyrtosiphon pisum Harris), the invasive Asian brown marmorated stink bug (Halyomorpha halys Stål) and the invasive South American green vegetable stink bug (Nezara viridula L.). A preliminary study showed differential expressions in bacterial proteins in salivary glands when N. viridula were exposed to tomato with or without glandular trichomes. This led to questioning whether the internal symbionts influence the adaptability of the pest to the host by manipulating saliva compounds. Then, a study can be led to assess the impact of symbiont profiles on pea aphid saliva proteins. We also began to analyse the impact of several diets on stink bugs salivary glands proteome. We use especially proteomic techniques, such as SDS-PAGE and 2D-DIGE followed by LC-MS/MS and MALDI-TOF analysis, but also liquid chromatography gel free approaches. The perspective would be applying saliva or salivary glands extracts on plant in order to screen its defensive responses by complementary “omic” approaches and, in term, to identify candidate proteins playing a role in plant defence induction or bypass. [less ▲]

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See detailHemispheric specialization during mental imagery of brisk walking.
Cremers, Julien ULg; Dessoullieres, Aurélie; Garraux, Gaëtan ULg

in Human Brain Mapping (2011)

OBJECTIVES: Brisk walking, a sensitive test to evaluate gait capacity in normal and pathological aging such as parkinsonism, is used as an alternative to classical fitness program for motor rehabilitation ... [more ▼]

OBJECTIVES: Brisk walking, a sensitive test to evaluate gait capacity in normal and pathological aging such as parkinsonism, is used as an alternative to classical fitness program for motor rehabilitation and may help to decrease the risk of cognitive deterioration observed with aging. In this study, we aimed to identify brain areas normally involved in its control. METHODS: We conducted a block-design blood oxygen level dependent function magnetic resonance imaging (BOLD fMRI) experiment in 18 young healthy individuals trained to imagine themselves in three main situations: brisk walking in a 25-m-long corridor, standing or lying. Imagined walking time (IWT) was measured as a control of behavioral performance during fMRI. RESULTS: The group mean IWT was not significantly different from the actual walking time measured during a training session prior to the fMRI study. Compared with other experimental conditions, mental imagery (MI) of brisk walking was associated with stronger activity in frontal and parietal regions mainly on the right, and cerebellar hemispheres, mainly on the left. Presumed imagined walking speed (2.3 +/- 0.4 m/s) was positively correlated with activity levels in the right dorsolateral prefrontal cortex and posterior parietal lobule along with the vermis and the left cerebellar hemisphere. INTERPRETATIONS: A new finding in this study is that MI of brisk walking in young healthy individuals strongly involves processes lateralized in right fronto-parietal regions along with left cerebellum. These results show that brisk walking might be a non automatic locomotor activity requiring a high-level supraspinal control. Hum Brain Mapp, 2011. (c) 2011 Wiley-Liss, Inc. [less ▲]

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See detailHemiurothorax following diaphragmatic hernia and kidney prolapse in a cat.
Stork, Christoph; Hamaide, Annick ULg; Schwedes, Claudia et al

in Journal of Feline Medicine and Surgery (2003), 5(2), 91-96

A 3-year-old cat was presented with increasing dyspnoea over the past four days. Unilateral pleural effusion was diagnosed and a modified transudate was drained several times. Surgical exploration ... [more ▼]

A 3-year-old cat was presented with increasing dyspnoea over the past four days. Unilateral pleural effusion was diagnosed and a modified transudate was drained several times. Surgical exploration revealed intra-thoracic prolapse of the left kidney and partial herniation of the spleen through a dorsal, circumferential diaphragmatic tear. Biochemical analysis of the pleural fluid confirmed urothorax. Due to excessive fibrin deposit on the well-vascularised kidney it was impossible to re-establish left urinary pathways. Left-sided nephrectomy and diaphragmatic herniorrhaphy were performed. Postoperative recovery was uneventful and complete. This is the first report of an urothorax in veterinary medical literature. (C) 2002 ESFM and AAFP. Published by Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailHemochromatose et diabete sucre: approche diagnostique et evolution clinique.
Thielen, Vinciane ULg; Radermecker, Régis ULg; Philips, Jean-Christophe ULg et al

in Revue Médicale de Liège (2005), 60(5-6), 448-54

We report the characteristics of diabetes mellitus in 10 patients with a suspicion of hereditary hemochromatosis. The results of this personal series were compared to literature's data described in a ... [more ▼]

We report the characteristics of diabetes mellitus in 10 patients with a suspicion of hereditary hemochromatosis. The results of this personal series were compared to literature's data described in a recent article. Early diagnosis and treatment by phlebotomy can improve blood glucose control in the early stages of the disease. If diagnosis occurs later, when the patient already needs insulin therapy, diabetes will not be improved by phlebotomy anymore. [less ▲]

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See detailHemochromatose et diabete.
Thielen, Vinciane ULg; Paquot, Nicolas ULg; Scheen, André ULg

in Revue Médicale de Liège (2004), 59(1), 29-31

Nowadays, haemochromatosis is often diagnosed when the patient is monosymptomatic. Diabetes is frequently the first expression of the disease. So, it is important to know the clinical and biologic ... [more ▼]

Nowadays, haemochromatosis is often diagnosed when the patient is monosymptomatic. Diabetes is frequently the first expression of the disease. So, it is important to know the clinical and biologic characteristics to evoke diagnosis as early as possible. Uncommon presentations request systematic screening. [less ▲]

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See detailHemocompatibility and biofunctionality of two poly(2- (dimethylamino)ethyl methacrylate-co-poly(ethyleneglycol) copolymers
Riquelme, Bibiana D.; Dumas, Dominique; Fontana, Alicia et al

in Journal of Biomedical Materials Research (2011), 99A (3)

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See detailHemocompatibility assessment of poly(2-dimethylamino ethylmethacrylate) (PDMAEMA)-based polymers
Cerda Cristerna, Bernardino Isaac ULg; Flores, Héctor; Pozos-Guillén, Amaury et al

in Journal of Controlled Release (2011), 153(3), 269-77

Poly(2-dimethylamino-ethylmethacrylate) (PDMAEMA), a cationic polymer, has been widely reported as a nonviral carrier. Despite the fact that the cytotoxicity of this polymer has been extensively studied ... [more ▼]

Poly(2-dimethylamino-ethylmethacrylate) (PDMAEMA), a cationic polymer, has been widely reported as a nonviral carrier. Despite the fact that the cytotoxicity of this polymer has been extensively studied, there is a lack of information about its blood compatibility. Hence, this work evaluates the hemocompatibility of free-form PDMAEMA homopolymers differing in molecular weight (Mw) with or without a poly(ethylene glycol) (PEG) sequence in the form of a palm tree-like structure. Poly(ethylenimine) (PEI) was used as a reference in order to compare its hemoreactivity. Hemagglutination, hemolysis, platelet number, blood coagulation, and the complement systems were assessed in normal human whole blood according to the ISO 10993-4. Results showed that Mw, concentration, and incubation time strongly affected the hemocompatibility of the polymers evaluated. Our in vitro observations highlight that PDMAEMA homopolymers interacted strongly with the surface of the red blood cells but not with the inner structure of the membrane, while PEI behaved in the opposite way. No clear correlation has been evidenced between PDMAEMA-induced hemagglutination, PEI-induced hemagglutination, and hemolysis. Interestingly, if these polyelectrolytes strongly affect the platelets and blood coagulation cascades in a dose dependent way, none of them significantly affects the complement system. Our work reveals new knowledge on the toxicology of 2 families of polycations largely explored for gene delivery and on their mechanisms of cellular and humoral interactions. [less ▲]

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See detailHemocompatibility of liposomes loaded with lipophilic prodrugs of methotrexate and melphalan in the lipid bilayer
Kuznetsova, Natalia R.; Sevrin, Chantal ULg; Lespineux, David et al

in Journal of Controlled Release (2012)

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See detailHemocompatibility of nanocarriers designed to transport biopharmaceutical drugs
Sevrin, Chantal ULg; Cerda, Bernardino; Lombart, François ULg et al

Poster (2012, April 18)

The optimization of nanoparticles (NP) for drug delivery, in particular to target the BBB, imposes to verify their hemocompatibility both for toxicological and efficiency of targeting perspectives. Indeed ... [more ▼]

The optimization of nanoparticles (NP) for drug delivery, in particular to target the BBB, imposes to verify their hemocompatibility both for toxicological and efficiency of targeting perspectives. Indeed the large surface they are able to expose to the biological environment promotes their interaction with various biochemicals, in particular proteins which can after adsorption elicit the activation of biological cascades either responsible from NP clearance or/and harmful body reaction (inflammatory / coagulation). In the frame of the European Integrated Project : “Nanobiopharmaceutics”, we have the opportunity to compare the hemoreactivity of about 145 different NP samples differing in core and surface chemistry and classified according to their expected difference in hydrophobicity based on the nature of their core materials. According to this classification, PLGA nanoparticles, polyglycidol-polyethyethylene oxide nanoparticles, polyglycidol thyolated or polyacrylamide nanogels, and polyelectrolyte complexes either based on polyamidoamine or poly(N,N-dimethylamino-2-ethylmethacrylate) have been evaluated within a concentration ranging from 0.3 to 1000 =g/mL. These in vitro tests have been realized for screening purpose adopting normal human bloods and according to Iso 10993. As a summary of this extensive study, our results clearly highlight that most of the polymeric nanoparticles evaluated give rise to some alterations of the blood components. In particular the platelets, intrinsic pathway of coagulation and complement activation are the most reactive biological parameters in the presence of these nanostuctures. Although not strictly related to the surface chemistry our classification has also allowed us to derive some clear correlations between nanomaterial properties and their hemoreactivity. Within the class of polyelectrolyte electrolyte complexes, the modifications brought in the surface chemistry has drastically improved their hemoreactivity. [less ▲]

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See detailHemocompatibility of nanoparticles designed for drug delivery
Grandfils, Christian ULg; Sevrin, Chantal ULg; Cerda, Bernardino

Conference (2010, November 24)

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See detailHemocompatibility study of new functionalized polycations tailored to modify the surface properties of red blood cells
Grandfils, Christian ULg; Riquelme, B; Foresto, P et al

Conference (2007, June 19)

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See detailHemocompatibility study of new polycations tailored to mask the antigens of the red blood cells
Grandfils, Christian ULg; Sevrin, Chantal ULg; Foresto, P et al

in Proceeding of the International Conference on Nanomedicine (2007)

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See detailHemocompatible polyelectrolyte microparticles loaded with synthetic glycoconjugates as novel immunosorbents
Markvicheva, E; Selina, O; Bartkowiak, A et al

Conference (2010, October 01)

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See detailHemodiafiltration does not improve haemodynamics in a porcine model of endotoxin shock.
LAMBERMONT, Bernard ULg; Moonen, Martial; KOLH, Philippe ULg et al

in Intensive Care Medicine (2001), 27(2),

Detailed reference viewed: 24 (2 ULg)