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See detailFocus cardiac ultrasound: the European Association of Cardiovascular Imaging viewpoint.
Neskovic, Aleksandar N.; Edvardsen, Thor; Galderisi, Maurizio et al

in European heart journal cardiovascular Imaging (2014)

The concept of point-of-care, problem-oriented focus cardiac ultrasound examination (FoCUS) is increasingly applied in the settings of medical emergencies, including cardiac diseases. The European ... [more ▼]

The concept of point-of-care, problem-oriented focus cardiac ultrasound examination (FoCUS) is increasingly applied in the settings of medical emergencies, including cardiac diseases. The European Association of Cardiovascular Imaging (EACVI) recognizes that cardiologists are not the only medical professionals dealing with cardiovascular emergencies. In reality, emergency cardiac diagnostics and treatment are also carried out by a wide range of specialists. For the benefit of the patients, the EACVI encourages any medical professional, sufficiently trained to obtain valuable information from FoCUS, to use it in emergency settings. These medical professionals need to have the necessary knowledge to understand the obtained information entirely, and to use it correctly, thoughtfully and with care. In this document, the EACVI underlines major differences between echocardiography and FoCUS, and underscores the need for specific education and training in order to fully utilize advantages and minimize drawbacks of this type of cardiac ultrasound examination in the critically ill patients. [less ▲]

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See detailFocus on skin cancer association and progression under TNF antagonist therapy.
PIERARD-FRANCHIMONT, Claudine ULiege; PIERARD, Gérald ULiege; QUATRESOOZ, Pascale ULiege

in Expert Opinion on Biological Therapy (2011), 11(9), 1215-22

INTRODUCTION: Basal and squamous cell carcinomas are the most common non-melanoma skin cancers (NMSC) in humans. Their prevalence is higher in immunocompromized patients. Results of some animal ... [more ▼]

INTRODUCTION: Basal and squamous cell carcinomas are the most common non-melanoma skin cancers (NMSC) in humans. Their prevalence is higher in immunocompromized patients. Results of some animal experiments have indicated that TNF acts both as a tumour promotor and an inductor of apoptosis. AREAS COVERED: Peer-reviewed articles about human skin cancers possibly related to TNF antagonists. The occurrence and growth kinetics of NMSC are possibly increased in some patients under TNF antagonist therapy. Other issues of such biological treatment suggested include the activation of other distinct skin malignancies, including malignant melanoma. Benign melanocytic tumours appear to be boosted as well. At present, most of the reported findings only represent anecdotal case reports. The influence of cumulative co-factors must not be neglected, particularly the effect of other therapies administered to the patients. The occurrence of antibodies to some TNF antagonists may decrease both the treatment efficacy and the risk of skin cancer progression. EXPERT OPINION: More research needs to be performed in order to firmly establish and understand the risk of anti-TNF biologicals in the area of human skin cancers. At present, NMSC progression appears to be boosted on areas of skin field cancerization. Benign melanocytic naevi may develop as well. [less ▲]

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See detailFocus on the epidemiology of metabolic syndrome in Luxembourg. Data from ORISCAV-LUX study
Alkerwi, A; Lair, ML; Guillaume, Michèle ULiege

Conference (2010)

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See detailFocus sur les astrocytes: cellules de la glie aux rôles multiples et importants dans le SNC. Le mouton est-il un excellent modèle animal ?
Salouci, Moustafa ULiege; Gabriel, Annick ULiege

in Revue de Médecine Vétérinaire (2016)

Les astrocytes représentent la population la plus importante de cellules gliales au sein du système nerveux central (SNC). Leur participation au fonctionnement du système nerveux central et leurs contacts ... [more ▼]

Les astrocytes représentent la population la plus importante de cellules gliales au sein du système nerveux central (SNC). Leur participation au fonctionnement du système nerveux central et leurs contacts avec les éléments neuronaux impliquent pour ces cellules des rôles très importants lors du développement du système nerveux, dans le cadre de différentes fonctions vitales et également lors de processus pathologiques. En plus d’être un soutien structurel, ces cellules jouent un rôle dans le métabolisme, la production et la libération de différentes molécules, l'entretien et le remplacement des neurones ; elles assurent également des fonctions immunitaires. La similitude entre l’être humain et le mouton en ce qui concerne certains aspects développementaux et anatomiques a donné de l'importance à ce dernier en tant que modèle expérimental animal permettant de mieux comprendre les rôles joués par les astrocytes dans les processus vitaux et pathologiques. Le but de cet article est de réaliser une synthèse sur le développent et les fonctions des astrocytes et leurs interventions lors de pathologie du SNC chez l’homme et chez le mouton. Enfin, l’utilisation du mouton en tant que modèle animal dans le cadre d’études expérimentales concernant les astrocytes est abordée. [less ▲]

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See detailFocus sur les lymphocytes T dans la maladie du greffon contre l'hôte après allogreffe de cellules soucges hématopoïétiques: implications pour de nouvelles stratégies de prévention
Vrancken, L; Delens, Loïc ULiege; BEGUIN, Yves ULiege et al

in Oncol. Hematol. (2017), 11

Malgré les stratégies de prévention actuelles, la maladie du greffon contre l’hôte (greffe-versus-hôte, GVH) aiguë (GVHa) reste une complication sévère et fréquente de l’allogreffe de cellules souches ... [more ▼]

Malgré les stratégies de prévention actuelles, la maladie du greffon contre l’hôte (greffe-versus-hôte, GVH) aiguë (GVHa) reste une complication sévère et fréquente de l’allogreffe de cellules souches hématopoïétiques. Bien que la physiopathologie de celle-ci ne reste que partiellement élucidée à ce jour, il est classiquement admis que les lymphocytes T (LT) jouent un rôle important dans son processus biologique. Les progrès récents de l’immunologie des LT dans la GVHa ont permis de diversifier les pistes visant à prévenir la survenue de cette complication post-greffe. Plusieurs approches sont en cours d’exploration dans des essais cliniques avec des résultats encourageant tels que la manipulation ex vivo des LT avant leur transfert chez le patient afin de leur faire exprimer des gènes suicide, l’élimination in vivo des LT proliférant directement après la greffe, l’inhibition de l’activation des LT en interférant avec les voies de signalisation en aval du TCR ou celles induites par les cytokines, l’induction de l’anergie des LT en bloquant les signaux de costimulation, le blocage de l’adressage des LT vers les organes lymphoïdes secondaires et les tissus cibles, la promotion de l’immunotolérance par la perfusion de lymphocytes T régulateurs ou par l’utilisation d’agents favorisant leur différenciation et leurs fonctions in vivo et la modulation de l’expression génique des cellules immunitaires par des modulateurs épigénétiques. Outre la prévention de la GVHa, le défi des nouvelles stratégies consiste également à ne pas compromettre l’effet bénéfique de la greffe contre la tumeur ni la reconstitution des défenses anti-infectieuses. [less ▲]

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See detailFodder Biomass Monitoring in Sahelian Rangelands Using Phenological Metrics from FAPAR Time Series
Diouf, Abdoul Aziz; Brandt, Martin; Verger, Aleixandre et al

in Remote sensing (2015), 7(9122-9148),

Timely monitoring of plant biomass is critical for the management of forage resources in Sahelian rangelands. The estimation of annual biomass production in the Sahel is based on a simple relationship ... [more ▼]

Timely monitoring of plant biomass is critical for the management of forage resources in Sahelian rangelands. The estimation of annual biomass production in the Sahel is based on a simple relationship between satellite annual Normalized Difference Vegetation Index (NDVI) and in situ biomass data. This study proposes a new methodology using multi-linear models between phenological metrics from the SPOT-VEGETATION time series of Fraction of Absorbed Photosynthetically Active Radiation (FAPAR) and in situ biomass. A model with three variables—large seasonal integral (LINTG), length of growing season, and end of season decreasing rate—performed best (MAE = 605 kg·DM/ha; R2 = 0.68) across Sahelian ecosystems in Senegal (data for the period 1999–2013). A model with annual maximum (PEAK) and start date of season showed similar performances (MAE = 625 kg·DM/ha; R2 = 0.64), allowing a timely estimation of forage availability. The subdivision of the study area in ecoregions increased overall accuracy (MAE = 489.21 kg·DM/ha; R2 = 0.77), indicating that a relation between metrics and ecosystem properties exists. LINTG was the main explanatory variable for woody rangelands with high leaf biomass, whereas for areas dominated by herbaceous vegetation, it was the PEAK metric. The proposed approach outperformed the established biomass NDVI-based product (MAE = 818 kg·DM/ha and R2 = 0.51) and should improve the operational monitoring of forage resources in Sahelian rangelands. [less ▲]

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See detailFoedera aequa entre Rome et les cités grecques : nouveaux documents, nouvelles perspectives
Famerie, Etienne ULiege

Conference (2011, September 21)

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See detailFoetus et nouveau-né: deux poids, deux mesures
Battisti, Oreste ULiege

Conference (1999)

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See detailA fog forecasting method in a deeply embanked valley.
Boreux, Jean-Jacques ULiege; Guiot, Joël

in Atmospheric Environment, Part A : General Topics (1992), 26(5), 759-764

This paper presents a statistical model used to forecast fog in the Meuse Valley in Belgium. The method is a bootstrap discriminant analysis using eight predictors: river surface temperature, air pressure ... [more ▼]

This paper presents a statistical model used to forecast fog in the Meuse Valley in Belgium. The method is a bootstrap discriminant analysis using eight predictors: river surface temperature, air pressure, air temperature at two elevations, wind speed and relative humidity at the same two locations. These data are measured from November 1989 to April 1990. Tests are done to determine the number of resampling needed for this data set and the optimum projection delay for prediction from the meteorological data. The best results are obtained for the prediction at 0700h UT using meteorological data at 0400 h UT. [less ▲]

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See detailLa foi de Charlemagne
Close, Florence ULiege

Scientific conference (2013, January 24)

En 2000, Henri Mayr-Harting contesta l’idée qu’Arnold Angenendt se faisait de la religion de Charlemagne . Au modèle d’une religion magique, essentiellement propitiatoire, il opposa un certain génie ... [more ▼]

En 2000, Henri Mayr-Harting contesta l’idée qu’Arnold Angenendt se faisait de la religion de Charlemagne . Au modèle d’une religion magique, essentiellement propitiatoire, il opposa un certain génie éthique carolingien teinté de quelques supports quasi-magiques et posa les jalons d’une enquête sur le sens profond de la religion de Charlemagne, son contenu éthique et son objet. Tout en admettant qu’on ne connaîtrait jamais les convictions personnelles de Charlemagne, il a avancé l’hypothèse qu’on était en mesure d’entendre sa voix dans certains documents faisant échos à un débat qui aurait opposé différents membres de la cour. Confortée par les recherches d’Henry Mayr-Harting, cette conférence visait à évaluer la sincérité des convictions religieuses de celui qui déploya tous les moyens matériels, militaires et humains qu’il avait à sa disposition, pour enseigner à son peuple ce qu’il était nécessaire de croire pour être sauvé. [less ▲]

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See detailFoi et démocratie. Débat contradictoire avec le R.P. Ignace Berten, O.P.
Seba, Jean-Renaud ULiege

Conference given outside the academic context (2008)

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See detailFoi et Modernité aux XIXe-XXe s. : quelle(s) transaction(s) ?
Jadoulle, Jean-Louis ULiege

Scientific conference (1993, September 15)

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See detailFoie et maladies inflammatoires du tube digestif
Belaiche, Jacques ULiege; Houbiers, G.; Louis, Edouard ULiege

in Médecine et Hygiène (1995), 53

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See detailLe foie, laboratoire des réserves alimentaires
Fredericq, Léon ULiege

in Revue Générale des Sciences Pures et Appliquées (1892), (11), 400-407

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See detailLa Foire du livre, terrain d'enquête
Barnabé, Fanny ULiege; Bertrand, Charlotte ULiege; Duchesne, Laurence

Article for general public (2012)

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See detail"Une fois devant, ils aimeront": médiation culturelle, appropriation et non-publics en banlieue parisienne
Ghebaur, Cosmina ULiege

in Derlon, Brigitte; Jeudy-Ballini, Monique (Eds.) L'art en transfert (2015)

La politique de décentralisation menée en France depuis une quinzaine d’années s’est notamment traduite par l’investissement croissant des villes dans le secteur culturel. On observe cependant que ... [more ▼]

La politique de décentralisation menée en France depuis une quinzaine d’années s’est notamment traduite par l’investissement croissant des villes dans le secteur culturel. On observe cependant que certains des dispositifs institutionnellement mis en place pour créer du lien entre des publics et des œuvres produisent au contraire des résistances ou des réticences. L’article s’attachera à montrer le rôle que joue, sur ce point, la vision de l’appropriation sous-tendant de tels dispositifs. A travers un exemple (la réception d’une pièce de théâtre classique dans un centre social d’une cité de la banlieue parisienne), il s’agira de réfléchir sur l’idée que les acteurs institutionnels se font d’une appropriation réussie. On s’interrogera aussi sur les normes, registres de valeurs et critères d’évaluation mobilisés ou encore sur les espaces sociaux dans lesquels l’évaluation est menée. [less ▲]

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See detailFolate receptor autoantibodies and spinal fluid 5-methyltetrahydrofolate deficiency in Rett syndrome
Ramaekers, Vincent ULiege; Sequeira, J. M.; Artuch, R. et al

in Neuropediatrics (2007), 38(4), 179-183

Rett syndrome was associated with low cerebrospinal fluid (CSF) 5-methyltetrahydrofolate (5MTHF) in 42-50% of European patients whereas approximately 93% of the patients from North-America had a normal ... [more ▼]

Rett syndrome was associated with low cerebrospinal fluid (CSF) 5-methyltetrahydrofolate (5MTHF) in 42-50% of European patients whereas approximately 93% of the patients from North-America had a normal CSF 5MTHF status. We determined the CSF folate status in Rett patients living in North- and South-Western Europe and measured serum folate receptor (FR) autoantibodies of the blocking type to explain the reduced folate transport across the choroid plexus. Irrespective of their MECP2 genotype and despite normal plasma folate values, 14 of 33 Rett patients (42%) had low CSF folate levels. Blocking FR autoantibodies were found in 8 of the Rett patients (24%), 6 of whom had low CSF folate levels. FR autoimmunity was primarily found within the group of Rett patients with low CSF folate status with a higher incidence in North-Western Europe. In Rett patients from North-America 74 of 76 girls had higher folate values in both serum and CSF than European patients. The food folate fortification in North-America may account for the higher folate levels and may prevent CFD in these Rett patients. FR autoimmunity occurred predominantly in Rett patients from North-Western Europe and may contribute to cerebral folate deficiency (CFD). © Georg Thieme Verlag KG Stuttgart. [less ▲]

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See detailFolate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits
RAMAEKERS, Vincent ULiege; Blau, N.; Sequeira, J. M. et al

in Neuropediatrics (2007), 38(6), 276-281

Reduced folate transport to the CNS was identified in two autism spectrum disorders, i.e., Rett syndrome and infantile low-functioning autism with neurological abnormalities. Twenty-five patients with ... [more ▼]

Reduced folate transport to the CNS was identified in two autism spectrum disorders, i.e., Rett syndrome and infantile low-functioning autism with neurological abnormalities. Twenty-five patients with early-onset low-functioning autism with or without neurological deficits, were evaluated for serum folate, cerebrospinal fluid (CSF) 5-methyltetrahydrofolate (5MTHF), and serum FR autoantibodies of the blocking type to determine the significance of folate receptor (FR) autoantibodies with respect to folate transport across the blood-CSF barrier. In spite of normal serum folate, CSF 5MTHF was low in 23 of 25 patients. The reduced CSF folate in 19 of these 23 patients could be explained by serum FR autoantibodies blocking the folate binding site of the membrane-attached FR on the choroid epithelial cells. Oral folinic acid supplements led to normal CSF 5MTHF and partial or complete clinical recovery after 12 months. Serum FR autoimmunity appears to represent an important factor in the pathogenesis of reduced folate transport to the nervous system among children with early-onset low-functioning autism associated with or without neurological deficits. Early detection of FR autoantibodies may be a key factor in the prevention and therapeutic intervention among this subgroup of patients with autism. © Georg Thieme Verlag KG Stuttgart. [less ▲]

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