Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailJuxtamembrane Protein Segments That Contribute To Recruitment Of Cholesterol Into Domains
Epand, Rf.; Thomas, Annick ULg; Brasseur, Robert ULg et al

in Biochemistry (2006), 45(19), 6105-14

We investigated the properties of several peptides with sequences related to LWYIK, a segment found in the gp41 protein of HIV and believed to play a role in sequestering this protein to a cholesterol ... [more ▼]

We investigated the properties of several peptides with sequences related to LWYIK, a segment found in the gp41 protein of HIV and believed to play a role in sequestering this protein to a cholesterol-rich domain in the membrane. This segment fulfills the requirements to be classified as a CRAC motif that has been suggested to predict those proteins that will partition into cholesterol-rich regions of the membrane. All of the peptides were studied with the terminal amino and carboxyl groups blocked, i.e., as N-acetyl-peptide-amides. Effects of cholesterol on the intensity of W emission generally parallel DSC evidence of sequestration of cholesterol. Modeling studies indicate that all of these peptides tend to partition with their mass center at the membrane interface at the level of the hydroxyl of cholesterol. Interaction with cholesterol is dual: van der Waals interactions between mainly hydrophobic surfaces and electrostatic stabilization of the cholesterol OH group. Thus, both experiments and modeling studies indicate that the preference of CRAC motifs for cholesterol-rich domains might be related to a membrane interfacial preference of the motif, to a capacity to wrap and block the cholesterol polar OH group by H-bond interactions, and to a capacity for peptide aromatic side chains to stack with cholesterol. These results were supported by studies of single mutations in the gp41 protein of HIV-1, in which L(679) is replaced with I. Despite the similarity of the properties of these amino acid residues, this single substitution resulted in a marked attenuation of the ability of JC53-BL HeLa-based HIV-1 indicator cells to form syncytia. [less ▲]

Detailed reference viewed: 7 (0 ULg)
See detailJuxtaposition des modes d'habiter dans les campagnes belges
Schmitz, Serge ULg

in Lugimbül, Yves (Ed.) Nouvelles urbanités, nouvelles ruralités en Europe (2007)

Detailed reference viewed: 43 (9 ULg)
Full Text
See detailThe JWST MIRI Double-Prism, Design and Science Drivers
Fisher, Sebastian; Rossi, Laurence ULg; Renotte, Etienne ULg et al

in Proceedings of SPIE (2008, July 12), 7010

We present how it is achieved to mount a double prism in the filter wheel of MIRIM - the imager of JWST’s Mid Infrared Instrument. In order to cope with the extreme conditions of the prisms’ surroundings ... [more ▼]

We present how it is achieved to mount a double prism in the filter wheel of MIRIM - the imager of JWST’s Mid Infrared Instrument. In order to cope with the extreme conditions of the prisms’ surroundings, the low resolution double prism assembly (LRSDPA) design makes high demands on manufacturing accuracy. The design and the manufacturing of the mechanical parts are presented here, while ’Manufacturing and verification of ZnS and Ge prisms for the JWST MIRI imager’ are described in a second paper [1]. We also give insights on the astronomical possibilities of a sensitive MIR spectrometer. Low resolution prism spectroscopy in the wavelength range from 5-10 microns will allow to spectroscopically determine redshifts of objects close to/at the re-ionization phase of the universe. [less ▲]

Detailed reference viewed: 12 (1 ULg)
See detailK voprosou bidelenii fatsii zoubtchatogo moustié na materialakh pamyatnikov sredneï azii
Krivoshapkin, A.; Kolobova, K.; Pavlenok, K. et al

Scientific conference (2011)

Detailed reference viewed: 26 (0 ULg)
Peer Reviewed
See detailLe K-ABC utilisé avec des enfants trisomiques 21 : Un essai d’adaptation
Frenkel, Stéphanie ULg; Bourdin, Béatrice; Vandromme, Luc

Conference (2001)

Detailed reference viewed: 18 (1 ULg)
See detailLe K-ABC utilisé avec des enfants trisomiques 21 : Un essai d’adaptation
Frenkel, Stéphanie ULg; Bourdin, Béatrice; Vandromme, luc

in Vivicorsi, Bruno; Collet, R. (Eds.) Handicap, cognition et prise en charge individuelle : des aspects de la recherche au respect de la personne (2005)

Detailed reference viewed: 50 (3 ULg)
Full Text
See detailK-excess, an unexploited method for discovering red quasars
Nakos, T.; Willis, J.; Andreon, S. et al

Conference (2006, May 19)

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailK-shell photoionization and photoabsorption of Ne, Mg, Si, S, Ar and Ca
Witthoeft, M; Bautista, M A; Mendoza, C et al

in Astrophysical Journal Supplement Series (2009), 182

Detailed reference viewed: 2 (0 ULg)
Full Text
Peer Reviewed
See detailK-shell photoionization of Na-like to Cl)like ions of Mg, Si, S, Ar and Ca
Witthoeft, M; Garcia, J; Kallman, T R et al

in Astrophysical Journal Supplement Series (2011), 192

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailK-shell photoionization of Nickel ions using R-matrix
Witthoeft, M C; Bautista, M A; Garcia, J et al

in Astrophysical Journal Supplement Series (2011), 196

Full Text
Peer Reviewed
See detailK-type geomagnetic index nowcast with data quality control
Stankov, Stanimir; Stegen, Koen; Warnant, René ULg

in Annals of Geophysics = Annali di Geofisica (2011), 54(3), 285-295

Detailed reference viewed: 39 (7 ULg)
Full Text
Peer Reviewed
See detailThe K1 beta-lactamase of Klebsiella pneumoniae.
Joris, Bernard ULg; De Meester, F; Galleni, Moreno ULg et al

in Biochemical Journal (1987), 243(2), 561-7

beta-Lactamase K1 was purified from Klebsiella pneumoniae SC10436. It is very similar to the enzyme produced by Klebsiella aerogenes 1082E and described by Emanuel, Gagnon & Waley [Biochem. J. (1986) 234 ... [more ▼]

beta-Lactamase K1 was purified from Klebsiella pneumoniae SC10436. It is very similar to the enzyme produced by Klebsiella aerogenes 1082E and described by Emanuel, Gagnon & Waley [Biochem. J. (1986) 234, 343-347]. An active-site peptide was isolated after labelling of the enzyme with tritiated beta-iodopenicillanate. A cysteine residue was found just before the active-site serine residue. This result could explain the properties of the enzyme after modification by thiol-blocking reagents. The sequence of the active-site peptide clearly established the enzyme as a class A beta-lactamase. [less ▲]

Detailed reference viewed: 15 (0 ULg)
See detailKaberdoes
Vromans, Joseph ULg

in Nederlands Van Nu (1993), 41(5),

Detailed reference viewed: 16 (2 ULg)
Full Text
See detail"Kadenzen des ganzen Körpers" - Das Sich-Bewegen des Musikers.
Viehöver, Vera ULg; Wunsch, Stephan

in Görling, Reinhold; Skrandies, Timo; Trinkaus, Stephan (Eds.) Geste - Bewegungen zwischen Film und Tanz (2009)

Detailed reference viewed: 80 (4 ULg)
Full Text
Peer Reviewed
See detailKainate and Nmda Toxicity for Cultured Developing and Adult Rat Spiral Ganglion Neurons: Further Evidence for a Glutamatergic Excitatory Neurotransmission at the Inner Hair Cell Synapse
Lefèbvre, Philippe ULg; Weber, T.; Leprince, Pierre ULg et al

in Brain Research (1991), 555(1), 75-83

In the inner ear, the excitatory amino acid glutamate is a proposed neurotransmitter acting at the synapse between hair cells and afferent auditory neurons. Using cultures of 5-day-old rat auditory ... [more ▼]

In the inner ear, the excitatory amino acid glutamate is a proposed neurotransmitter acting at the synapse between hair cells and afferent auditory neurons. Using cultures of 5-day-old rat auditory neurons, we show that the afferent auditory neuronal population can be divided, on the basis of its sensitivity to the neuronotoxic effect of glutamate and its analogs, in at least 3 subpopulations, one responding to N-methyl-D-aspartate (NMDA), one responding to kainate and a third minor one unresponsive to NMDA, kainic acid and glutamate. No toxic effect of quisqualate is observed. The use of specific antagonists (kynurenate and 2-amino-5-phosphonovalerate (DAP-5) demonstrates the specificity of the receptors to the excitatory amino acids on the afferent auditory neurons. Afferent auditory neurons from adult rats can also be cultured and in these preparations only the large neurons are sensitive to glutamate, kainate and NMDA while the small neurons are not responsive, suggesting that a glutamatergic neurotransmission occurs only at this synapse between the inner hair cells and the large radial afferent auditory neurons. We also show that, in vitro, the organ of Corti releases, in response to an increased potassium concentration and in the presence of calcium, a toxic activity for the afferent auditory neurons that is antagonized by kynurenate and DAP-5. Pathophysiological implications are discussed. [less ▲]

Detailed reference viewed: 24 (14 ULg)
Peer Reviewed
See detailKainic acid sensitivity of mammalian Purkinje cells in monolayer cultures.
Gibbs, W.; Neale, E. A.; Moonen, Gustave ULg

in Brain Research (1982), 256(1), 103-108

Detailed reference viewed: 12 (0 ULg)
Full Text
See detailKaiserschnitt beim Rind. Resultate einer internationalen Studie mit Beteiligung von gegen 700 Tierärzten
Hanzen, Christian ULg; Hirsbrunner Gaby

Scientific conference (2011, June 09)

Detailed reference viewed: 53 (3 ULg)