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See detailHigh Multiplicity Scheduling Problems and Just-In-Time Scheduling
Crama, Yves ULg

Conference (2010, April 22)

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See detailHigh neuron specific enolase levels in bronchoalveolar lavage fluid of patients with lung carcinoma: diagnostic value, relation to serum neuron specific enolase, and staging.
Dowlati, A; Bury, Thierry ULg; CORHAY, Jean-Louis ULg et al

in Cancer (1996), 77(10), 2039-43

BACKGROUND: High levels of neuron specific enolase (NSE) have recently been described in the bronchoalveolar lavage (BAL) fluid of patients with lung carcinoma. Although its value in serum has been ... [more ▼]

BACKGROUND: High levels of neuron specific enolase (NSE) have recently been described in the bronchoalveolar lavage (BAL) fluid of patients with lung carcinoma. Although its value in serum has been extensively studied, its diagnostic value in BAL fluid in terms of sensitivity, specificity, and predictive value have not been evaluated. In addition, its value in staging and relation to serum NSE are yet unknown. METHODS: NSE levels were determined on the same day in the BAL fluid and the sera of two groups of patients: those with newly diagnosed lung carcinoma and those with smoking related chronic obstructive pulmonary disease (COPD). Clinical TNM staging was also performed. Levels of NSE in BAL fluid were expressed as nanograms per 100 international units of lactate dehydrogenase. BAL fluid NSE levels of the two groups were compared with staging and serum NSE. RESULTS: A highly significant difference exists in BAL NSE in the two groups. For diagnostic purposes, the simultaneous measurements of serum NSE increases its sensitivity, but specificity remains unchanged. No correlation exists between BAL NSE and serum NSE, tumor size, nodal status, or the presence of metastases. BAL NSE is a better predictor of malignancy than serum NSE. CONCLUSION: BAL fluid measurements of NSE may have diagnostic value, specially if it is simultaneously measured in the serum. However, our study does not show any value for this technique in staging of lung carcinoma. Also it has no correlation with serum NSE. Studies will have to be performed to determine if BAL NSE can predict chemotherapeutic sensitivity. [less ▲]

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See detailHigh numbers of mobilized CD34+ cells collected in AML in first remission are associated with high relapse risk irrespective of treatment with autologous peripheral blood SCT or autologous BMT
Hengeveld, M.; Suciu, S.; Chelgoum, Y. et al

in Bone Marrow Transplantation (2015), 50

The faster hematopoietic recovery after autologous peripheral blood SCT (APBSCT) in patients with AML may be offset by an increased relapse risk as compared with autologous BMT (ABMT). The EORTC and ... [more ▼]

The faster hematopoietic recovery after autologous peripheral blood SCT (APBSCT) in patients with AML may be offset by an increased relapse risk as compared with autologous BMT (ABMT). The EORTC and GIMEMA Leukemia Groups conducted a trial (AML-10) in which they compared, as second randomization, APBSCT and ABMT in first CR patients without an HLA compatible donor. A total of 292 patients were randomized. The 5-year DFS rate was 41% in the APBSCT arm and 46% in the ABMT arm with a hazard ratio (HR) of 1.17; 95% confidence interval = 0.85–1.59; P = 0.34. The 5-year cumulative relapse incidence was 56% vs 49% (P = 0.26), and the 5-year OS 50% and 55% (P = 0.6) in the APBSCT and ABMT groups, respectively. APBSCT was associated with significantly faster recovery of neutrophils and platelets, shorter duration of hospitalization, reduced need of transfusion packed RBC and less days of intravenous antibiotics. In both treatment groups, higher numbers of mobilized CD34+ cells were associated with a significantly higher relapse risk irrespective of the treatment given after the mobilization. Randomization between APBSCT and ABMT did not result in significantly different outcomes in terms of DFS, OS and relapse incidence. [less ▲]

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See detailHigh order asymptotic analysis of twisted electrostatic problems
Nicolet, A.; Movchan, A. B.; Geuzaine, Christophe ULg et al

in Physica B: Condensed Matter (2007), 394(2), 335--338

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See detailHigh order asymptotic analysis of twisted electrostatic problems
Nicolet, A.; Movchan, A. B.; Geuzaine, Christophe ULg et al

in Proceedings of the 7th conference on Electrical, Transport and Optical Properties of Inhomogeneous Media (ETOPIM 7) (2006, July)

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See detailHigh order bandpass sigma delta interfaces for vibratory gyroscopes
Kraft, Michael ULg; Dong, Y; Redman-White, W

in Proc. IEE Sensors (2005)

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See detailHigh output [18F]FDOPA on AllInOne (Trasis) at commercial scale
Otabashi, Muhammad; Cascione, Christian; Lemaire, Christian ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (2015, May), 58

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See detailHigh Pathogenic Avian Influenza in Poultry Production Systems in Vietnam: Tentative Approach for an HACCP-like Risk Scoring Methodology
Le Bas, Cedric; Phan Dang, Thang ULg; Desvaux, Stéphanie et al

Scientific conference (2008, December 04)

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See detailHigh Performance Algorithms for High-Order High-Frequency Electromagnetic Scattering
Geuzaine, Christophe ULg

Scientific conference (2010, April 28)

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See detailHigh Performance DSSC Based on Semiconducting Oxides Prepared Through Soft Chemistry Processes
Dewalque, Jennifer ULg; Schrijnemakers, Audrey ULg; Thalluri, Venkata Visveswara Gopala Kris ULg et al

Conference (2013, July)

DSSCs have been reported by O’Regan and Grätzel in the early nineties as a very promising alternative to conventional photovoltaic silicon devices. Main benefits of these cells are their low cost as well ... [more ▼]

DSSCs have been reported by O’Regan and Grätzel in the early nineties as a very promising alternative to conventional photovoltaic silicon devices. Main benefits of these cells are their low cost as well as their mild manufacturing process. In most of the specific literature, DSSCs are made of TiO2 films prepared by doctor-blade or screen-printing of anatase nanoparticles paste. However, due to the random organization of the nanoparticles, pore accessibility by the dye and electrolyte could be incomplete. Moreover, some anatase crystallites could suffer from a lack of connectivity, leading to electron transfer issues. The strategy adopted by our group to improve photovoltaic efficiencies involves a templating-assisted process allowing the preparation of highly porous layers with well-ordered and accessible pores as well as improved crystallites connectivity. The main goal is to increase the film surface area and to perfectly control the mesostructure in order to maximize the adsorption of active dye and the electrolyte infiltration inside the porous network. This talk especially focuses on the templating-assisted synthesis of TiO2 and ZnO semiconducting layers used as photoelectrode in DSSCs. Besides, due to the surface area improvement as well as the perfect control of the pore organization and the pore size, the templating strategy can be an effective solution to overcome light harvesting and solid electrolyte filling limitations encountered in solid-state DSSCs. Special effort is paid to the tuning of the TiO2 and ZnO semiconducting layers mesostructure in order to match with solid-state DSSC applications. [less ▲]

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See detailHigh performance gel filtration as a tool for the monitoring of the purification steps of the Na channel protein
Bontemps, J; Grandfils, Christian ULg; Bettendorff, Lucien ULg et al

in Archives Internationales de Physiologie et de Biochimie (1985), 93

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See detailHigh performance of Booroola X Romanov ewes as permanent embryos donors
Brebion, P.; Beckers, Jean-François ULg; Guerin, Y. et al

in Elsen, J. M.; Thimonier, J.; Bodin, L. (Eds.) Les Colloques de l'I.N.R.A. (1990, July 16)

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See detailHigh plasma concentrations of sclerostin, an inhibitor of the Wnt signaling pathway in young horses affected by osteochondrosis
Serteyn, Didier ULg; Mendoza García, Luis ULg; Sandersen, Charlotte ULg et al

in Open journal of orthepedics (2014)

Osteochondrosis (OC) is a developmental disease in horses with a significant impact on the horse’s welfare and performance. The early disturbance of enchondral ossification progresses to inflammatory and ... [more ▼]

Osteochondrosis (OC) is a developmental disease in horses with a significant impact on the horse’s welfare and performance. The early disturbance of enchondral ossification progresses to inflammatory and healing process in older horses. Metabolic pathway analysis showed an obvious dysregulation of several signaling pathways related to cartilage formation and cartilage repair such as Wnt/β-catenin, Indian hedgehog and TGF-β signaling pathways. Other regulated genes appeared to be involved in high carbohydrate diet, abnormal insulin metabolism or inflammation. Sclerostin is an osteocyte-secreted soluble antagonist of the Wnt/β-catenin signaling pathway. It is crucial for osteoblast development and activity and is increased in naturally occurring lesions of equine osteochondrosis. The aim of this study is to compare the circulating sclerostin levels between OC-affected (n = 20) and healthy horses (n = 19). A significant linear regression between plasma sclerostin and age is observed especially in the healthy young horses. The mean plasma sclerostin concentration is significantly higher in young horses suffering from osteochondrosis compared to the control horses. These results reinforce the possible role of the Wnt/β-catenin signaling pathway in the OC pathogeny. The inhibition of this essential pathway could disturb the osteo-chondral differentiation. More studies are currently needed to define the eventual clinic interest of plasma sclerostin as future biomarker in bone and cartilage diseases. [less ▲]

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See detailHigh precision astrometry mission for the detection and characterization of nearby habitable planetary systems with the Nearby Earth Astrometric Telescope (NEAT)
Malbet, Fabien; Léger, Alain; Shao, Michael et al

in Experimental Astronomy (2012), 34(2), 385-413

A complete census of planetary systems around a volume-limited sample of solar-type stars (FGK dwarfs) in the Solar neighborhood (d ≤ 15 pc) with uniform sensitivity down to Earth-mass planets within ... [more ▼]

A complete census of planetary systems around a volume-limited sample of solar-type stars (FGK dwarfs) in the Solar neighborhood (d ≤ 15 pc) with uniform sensitivity down to Earth-mass planets within their Habitable Zones out to several AUs would be a major milestone in extrasolar planets astrophysics. This fundamental goal can be achieved with a mission concept such as NEAT—the Nearby Earth Astrometric Telescope. NEAT is designed to carry out space-borne extremely-high-precision astrometric measurements at the 0.05 μas (1 σ) accuracy level, sufficient to detect dynamical effects due to orbiting planets of mass even lower than Earth's around the nearest stars. Such a survey mission would provide the actual planetary masses and the full orbital geometry for all the components of the detected planetary systems down to the Earth-mass limit. The NEAT performance limits can be achieved by carrying out differential astrometry between the targets and a set of suitable reference stars in the field. The NEAT instrument design consists of an off-axis parabola single-mirror telescope (D = 1 m), a detector with a large field of view located 40 m away from the telescope and made of 8 small movable CCDs located around a fixed central CCD, and an interferometric calibration system monitoring dynamical Young's fringes originating from metrology fibers located at the primary mirror. The mission profile is driven by the fact that the two main modules of the payload, the telescope and the focal plane, must be located 40 m away leading to the choice of a formation flying option as the reference mission, and of a deployable boom option as an alternative choice. The proposed mission architecture relies on the use of two satellites, of about 700 kg each, operating at L2 for 5 years, flying in formation and offering a capability of more than 20,000 reconfigurations. The two satellites will be launched in a stacked configuration using a Soyuz ST launch vehicle. The NEAT primary science program will encompass an astrometric survey of our 200 closest F-, G- and K-type stellar neighbors, with an average of 50 visits each distributed over the nominal mission duration. The main survey operation will use approximately 70% of the mission lifetime. The remaining 30% of NEAT observing time might be allocated, for example, to improve the characterization of the architecture of selected planetary systems around nearby targets of specific interest (low-mass stars, young stars, etc.) discovered by Gaia, ground-based high-precision radial-velocity surveys, and other programs. With its exquisite, surgical astrometric precision, NEAT holds the promise to provide the first thorough census for Earth-mass planets around stars in the immediate vicinity of our Sun. [less ▲]

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See detailHigh precision determination of the atmospheric parameters and abundances of the COROT main targets
Gillon, Michaël ULg; Magain, Pierre ULg

in Astronomy and Astrophysics (2006), 448

Context: .One of the main goals of the COROT mission is to get precise photometric observations of selected bright stars in order to allow the modelling of their interior through asteroseismology. However ... [more ▼]

Context: .One of the main goals of the COROT mission is to get precise photometric observations of selected bright stars in order to allow the modelling of their interior through asteroseismology. However, in order to interpret the asteroseismological data, the effective temperature, surface gravity, and chemical composition of the stars must be known with sufficient accuracy.Aims.To carry out this task, we have developed a spectroscopic method called APASS (Atmospheric Parameters and Abundances from Synthetic Spectra) which allows precise analysis of stars with a moderate to high rotational velocity, which is the case for most primary COROT targets.Methods.Our method is based on synthetic spectra in which individual lines are replaced by analysis units (isolated lines or line blends, depending on the crowding of the spectral region and on the rotational broadening). It works differentially with respect to the Sun and allows the atmospheric parameters and chemical abundances to be determined by considering analysis units with different sensitivities to these various parameters.Results.Using high signal-to-noise spectra and the APASS method, we determined the atmospheric parameters and chemical abundances of 13 primary COROT targets. Our results agree well with those obtained by Bruntt using his software VWA and with those obtained with the software TEMPLOGG. However, in both cases, our error bars are significantly smaller than those of other methods. Our effective temperatures are also in excellent agreement with those obtained with the IR photometry method. For five stars with relatively low rotational velocity, we also performed an analysis with a classical equivalent-width method to test agreement with APASS results. We show that equivalent-width measurements by Gaussian or Voigt profile-fitting are sensitive to the rotational broadening, leading to systematic errors whenever the projected rotation velocity is non-negligible. The APASS method appears superior in all cases and should thus be preferred. [less ▲]

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See detailHigh precision photometry in crowded stellar fields
Magain, Pierre ULg; Courbin, Frédéric; Gillon, Michaël ULg et al

in SPIE Newsroom (2006)

A deconvolution-based method which allows to derive high-precision photometry of stars in crowded fields, proves very useful for a variety of astronomical projects, including transit searches for ... [more ▼]

A deconvolution-based method which allows to derive high-precision photometry of stars in crowded fields, proves very useful for a variety of astronomical projects, including transit searches for extrasolar planets. [less ▲]

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See detailHigh predictive value of LDH in acute myocardial infarction
Chapelle, Jean-Paul ULg

Conference (1980, February 04)

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See detailA high pressure cell for supercritical CO2 on-line chemical reactions studied with x-ray techniques
Hermida-Merino, Daniel; Portale, Giuseppe; Fields, Peter et al

in Review of Scientific Instruments (2014), 85

A versatile high pressure X-ray sample cell has been developed for conducting in situ time-resolved X-ray scattering experiments in the pressure and temperature regime required (pressures up to 210 bars ... [more ▼]

A versatile high pressure X-ray sample cell has been developed for conducting in situ time-resolved X-ray scattering experiments in the pressure and temperature regime required (pressures up to 210 bars and temperatures up to 120 °C) for chemical reactions in supercritical fluids. The large exit opening angle of the cell allows simultaneous performance of SAXS-WAXS experiments. Diamond windows are used in order to benefit from the combination of maximum strength, minimal X-ray absorption and chemical inertia. The sample cell can also be utilised for X-ray spectroscopy experiments over a wide range of photon energies. Results of the online synthesis of a block copolymer, poly(methyl methacrylate-block-poly(benzyl methacrylate), by Reversible Addition-Fragmentation Chain Transfer (RAFT) in a supercritical CO2 dispersion polymerisation will be discussed. The contribution of the density fluctuations, as function of temperature, to the X-ray scattering signal has been quantified in order to allow appropriate background subtractions [less ▲]

Detailed reference viewed: 105 (6 ULg)