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See detailFibres alimentaires chez le chien : influence de l'incorporation de pulpes de betterave ou de chicorée sur la digestibilité des nutriments et les concentrations plasmatiques de plusieurs métabolites
Diez, Marianne ULiege; Hornick, Jean-Luc ULiege; Van Eenaeme, Christian ULiege et al

in Revue de Médecine Vétérinaire (1997), 148

Cette étude relate les effets de la distribution de deux rations enrichies en pulpes de betterave ou de chicorée (7 p.100 ADF dans la matière sèche) en comparaison à une ration témoin sur les paramètres ... [more ▼]

Cette étude relate les effets de la distribution de deux rations enrichies en pulpes de betterave ou de chicorée (7 p.100 ADF dans la matière sèche) en comparaison à une ration témoin sur les paramètres fécaux, la digestibilité des principaux nutriments et plusieurs paramètres biochimiques (glucose, insuline, azote alpha-aminé, urée, cholestérol et triglycérides) mesurés à jeun ou pendant six heures après le repas chez huit chiens adultes en bonne santé. Les régimes enrichis en pulpes ont entraîné une augmentation significative de l'excrétion fécale totale, de l'excrétion de MS dans les matières fécales, une diminution de la teneur en MS des fèces ainsi qu'une diminution des coefficients de digestibilité des principaux nutriments. Le régime contenant la pulpe de betterave a entraîné une diminution de la glycémie à jeun, de l'insulinémie et des concentrations en triglycérides postprandiales, des concentrations en urée et en cholestérol mesurées avant et après le repas. Le régime contenant la pulpe de chicorée a provoqué une diminution de l'insulinémie postprandiale, des concentrations en urée et en cholestérol à jeun et après le repas. Ces deux types de pulpes, semblables par leur composition, induisent les mêmes types d'effets sur les paramètres fécaux et la digestibilité des nutriments, mais les effets systémiques sont plus importants lors de la distribution de pulpes de betterave. [less ▲]

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See detailFibres alimentaires chez le chien : VII. Intérêt dans le traitement diététique de l'animal obèse
Diez, Marianne ULiege; Istasse, Louis ULiege

in Annales de Médecine Vétérinaire (1997), 141

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with ... [more ▼]

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with particular emphasis on the incorporation of large quantities of dietary fibres in low-energy specific purpose food. At present time, no conclusions can be drawn from published studies [less ▲]

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See detailFibres alimentaires chez le chien II. Effets sur la vidange gastrique et le transit gastro-intestinal
Diez, Marianne ULiege; Istasse, Louis ULiege

in Annales de Médecine Vétérinaire (1997), 141

The aim of this second review is to summarize data on the duration of gastric emptying and on the transit time in the gastrointestinal tract of healthy dogs. An overview of the investigation techniques is ... [more ▼]

The aim of this second review is to summarize data on the duration of gastric emptying and on the transit time in the gastrointestinal tract of healthy dogs. An overview of the investigation techniques is also given. The incorporation of fibres in the diet is one of many other factors which influence the mechanisms of emptying in the gastrointestinal tract. The effect of dietary fibres is also discussed in other monogastric species [less ▲]

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See detailFibres alimentaires chez le chien III. Effets sur les structures intestinales et les fermentations. Applications dans le traitement de certains dysfonctionnements intestinaux
Diez, Marianne ULiege; Istasse, Louis ULiege

in Annales de Médecine Vétérinaire (1997), 141

Dietary fibres can modify the intestinal structure in dogs and other animal species. The main changes concern not only the morphology of the gastrointestinal tract but also the ultrastructures ... [more ▼]

Dietary fibres can modify the intestinal structure in dogs and other animal species. The main changes concern not only the morphology of the gastrointestinal tract but also the ultrastructures. Furthermore, soluble and partly-soluble fibres are fermented in the large bowel; the fermentation products have different metabolic effects. The physical and chemical properties of fibres can be used for the dietary therapy of some intestinal pathologies [less ▲]

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See detailFibres alimentaires chez le chien IV. Effets sur les ingestions, le poids, les matières fécales et sur la digestibilité des nutriments
Diez, Marianne ULiege; Istasse, Louis ULiege

in Annales de Médecine Vétérinaire (1997), 141

The present paper summarizes the influence of diets enriched with fibres on voluntary feed intakes, bodyweight changes of dogs and feces. Fibres affect nutrients digestibility by different mechanisms. The ... [more ▼]

The present paper summarizes the influence of diets enriched with fibres on voluntary feed intakes, bodyweight changes of dogs and feces. Fibres affect nutrients digestibility by different mechanisms. The induced changes vary according to the types of fibre-soluble, insoluble or both- and are, on the whole, quite similar with dogs as in other monogastric species. [less ▲]

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See detailFibres alimentaires chez le chien V. Effets sur le métabolisme glucidique. Application dans le traitement du diabète
Diez, Marianne ULiege; Istasse, Louis ULiege

in Annales de Médecine Vétérinaire (1997), 141

Some dietary fibres are characterized by hypoglycaemic and hypoinsulinemic effects in humans and in carnivores. At present, these properties are used in the treatment of diabetes mellitus in both species ... [more ▼]

Some dietary fibres are characterized by hypoglycaemic and hypoinsulinemic effects in humans and in carnivores. At present, these properties are used in the treatment of diabetes mellitus in both species. Finally, the dietary treatment of the diabetic dog is presented with a particular emphasis on the use of dietary fibres. [less ▲]

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See detailFibres alimentaires chez le chien VI. Effets sur le métabolisme lipidique, les sécrétions biliaires et application dans le traitement de l'obésité
Diez, Marianne ULiege; Istasse, Louis ULiege

in Annales de Médecine Vétérinaire (1997), 141(5), 363-372

Dietary fibres are able to affect lipids profiles in humans. The soluble and partly soluble fibres have mainly been studied in this purpose. Although hyperlipidaemia are known in dogs, there are few ... [more ▼]

Dietary fibres are able to affect lipids profiles in humans. The soluble and partly soluble fibres have mainly been studied in this purpose. Although hyperlipidaemia are known in dogs, there are few studies on the subject. The mechanisms by which fibres are involved are discussed with a particular emphasis on bile secretion. [less ▲]

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See detailFibres et diabète.
Diez, Marianne ULiege

in Congrès CNVSPA-AFVAC-SAVAB, Les grands syndromes (2001, November)

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See detailFibril formation by human lysozyme
Dumoulin, Mireille ULiege

Conference (2010, April 08)

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See detailThe fibrillar centres and their relationships with the other nucleolar components
Goessens, Guy ULiege; Lepoint, Alain; Thiry, Marc ULiege

Poster (1985)

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See detailFibrillar type I collagens enhance platelet-dependent thrombin generation via glycoprotein VI with direct support of alpha2beta1 but not alphaIIbbeta3 integrin.
Lecut, Christelle ULiege; Feijge, Marion A H; Cosemans, Judith M E M et al

in Thrombosis and Haemostasis (2005), 94(1), 107-14

The role of collagens and collagen receptors was investigated in stimulating platelet-dependent thrombin generation. Fibrillar type-I collagens, including collagen from human heart, were most potent in ... [more ▼]

The role of collagens and collagen receptors was investigated in stimulating platelet-dependent thrombin generation. Fibrillar type-I collagens, including collagen from human heart, were most potent in enhancing thrombin generation, in a way dependent on exposure of phosphatidylserine (PS) at the platelet surface. Soluble, non-fibrillar type-I collagen required pre-activation of integrin alpha2beta1 with Mn2+ for enhancement of thrombin generation. With all preparations, blocking of glycoprotein VI (GPVI) with 9O12 antibody abrogated the collagen-enhanced thrombin generation, regardless of the alpha2beta 1 activation state. Blockade of alpha2beta1 alone or antagonism of autocrine thromboxane A2 and ADP were less effective. Blockade of alphaIIbbeta3 with abciximab suppressed thrombin generation in platelet-rich plasma, but this did not abolish the enhancing effect of collagens. The high activity of type-I fibrillar collagens in stimulating GPVI-dependent procoagulant activity was confirmed in whole-blood flow studies, showing that these collagens induced relatively high expression of PS. Together, these results indicate that: i) fibrillar type-I collagen greatly enhances thrombin generation, ii) GPVI-induced platelet activation is principally responsible for the procoagulant activity of fibrillar and non-fibrillar collagens, iii) alpha2beta1 and signaling via autocrine mediators facilitate and amplify this GPVI activity, and iv) alphaIIbbeta3 is not directly involved in the collagen effect. [less ▲]

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See detailFibrillation auriculaire et anticoagulation chez le patient hémodialysé : une décision difficile
DELANAYE, Pierre ULiege; BOUQUEGNEAU, Antoine ULiege; DUBOIS, Bernard ULiege et al

in Néphrologie & Thérapeutique (2017)

Cardiovascular mortality of hemodialysis patients remains a major problem. The prevalence and incidence of atrial fibrillation in this population are more important than in the general population. The ... [more ▼]

Cardiovascular mortality of hemodialysis patients remains a major problem. The prevalence and incidence of atrial fibrillation in this population are more important than in the general population. The indication of antivitamin K therapy (AVK) in this context of atrial fibrillation must be weighted against the increased risk of bleeding. Unfortunately, and contrary to the general population, an indication of anticoagulation based on embolic or hemorrhagic risk scores is not as clearly established in the hemodialysis population. No prospective randomized study has investigated the benefit/risk balance of anticoagulant treatment in hemodialysis subjects. This article is a review of the current literature on this topic, showing the prevalence of thromboembolic but also bleeding events in the hemodialysis population. The impact of AVK treatment in this specific population is also reviewed. To the best of our knowledge, the indication of treatment must be individualized. [less ▲]

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See detailLa fibrillation auriculaire: une epidemie du troisieme age?
Kulbertus, Henri ULiege; Lancellotti, Patrizio ULiege

in Revue medicale de Liege (2014), 69(5-6), 301-8

Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. In its non valvular form, it appears as a disorder of the aged. Surprisingly, its incidence and prevalence have ... [more ▼]

Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. In its non valvular form, it appears as a disorder of the aged. Surprisingly, its incidence and prevalence have constantly been on the rise over the last decades to the extent that some authors nowadays call this phenomenon an "emerging epidemic". The reasons for that proliferation are not entirely elucidated. Obesity, which has simultaneously and similarly increased in frequency, might have played a significant role. AF is frequently pauci-symptomatic in the aged and can easily go unrecognized. Yet, it entails a higher mortality rate, carries a significant risk of thrombo-embolic events, in particular strokes, and may lead to heart failure. We shall briefly review the current epidemiologic aspects of AF and evoke the possible role of obesity. We shall then discuss the therapy of this disorder with a particular attention to the new oral anticoagulants. [less ▲]

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See detailFibrin glue is effective healing perianal fistulas in patients with Crohn's disease.
Grimaud, Jean-Charles; Munoz-Bongrand, Nicolas; Siproudhis, Laurent et al

in Gastroenterology (2010), 138(7), 2275-8122811

BACKGROUND & AIMS: Fibrin glue is a therapeutic for fistulas that activates thrombin to form a fibrin clot, which mechanically seals the fistula tract. We assessed the efficacy and safety of a ... [more ▼]

BACKGROUND & AIMS: Fibrin glue is a therapeutic for fistulas that activates thrombin to form a fibrin clot, which mechanically seals the fistula tract. We assessed the efficacy and safety of a heterologous fibrin glue that was injected into the fistula tracts of patients with Crohn's disease (ClinicalTrials.gov No. NCT00723047). METHODS: This multicenter, open-label, randomized controlled trial included patients with a Crohn's disease activity index < or =250 and fistulas between the anus (or low rectum) and perineum, vulva, or vagina, that drained for more than 2 months. Magnetic resonance imaging or endosonography was performed to assess fistula tracts and the absence of abscesses. Patients were stratified into groups with simple or complex fistulas and randomly assigned to receive fibrin glue injections (n = 36) or only observation (n = 41) after removal of setons. The primary end point was clinical remission at week 8, defined as the absence of draining, perianal pain, or abscesses. At week 8, a fibrin glue injection was offered to patients who were not in remission. RESULTS: Clinical remission was observed in 13 of the 34 patients (38%) of the fibrin glue group compared with 6 of the 37 (16%) in the observation group; these findings demonstrate the benefit of fibrin glue (odds ratio, 3.2; 95% confidence interval: 1.1-9.8; P = .04). The benefit seemed to be greater in patients with simple fistulas. Four patients in the fibrin glue group and 6 in the observation group had adverse events. CONCLUSIONS: Fibrin glue injection is a simple, effective, and well-tolerated therapeutic option for patients with Crohn's disease and perianal fistula tracts. [less ▲]

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See detailFibrine
Fredericq, Léon ULiege

in Richet, Charles (Ed.) Dictionnaire de physiologie. 006. Tome VI (1904)

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See detailFibrinogène
Fredericq, Léon ULiege

in Richet, Charles (Ed.) Dictionnaire de physiologie. 006. Tome VI (1904)

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See detailFibrinolyse intra-artérielle in situ des membres inférieurs
Van Damme, Hendrik ULiege; Trotteur, Geneviève ULiege; Jamblain, P. et al

in Revue Médicale de Liège (1992), 47(1), 25-41

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See detailFibrinolysis Shutdown in Severely Injured Trauma Patients: A New World to Explore.
TONGLET, Martin ULiege; D'ORIO, Vincenzo ULiege; GHUYSEN, Alexandre ULiege et al

in Journal of the American College of Surgeons (2017), 225(6), 831-832

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See detailFibroblast growth factor 23 in acute burn patients: Novel insights from an intact-form assay.
ROUSSEAU, Anne-Françoise ULiege; SOUBERBIELLE, Jean-Claude; DELANAYE, Pierre ULiege et al

in Burns : Journal of the International Society for Burn Injuries (2016)

INTRODUCTION: Fibroblast growth factor 23 (FGF23) is a key regulator in phosphate and vitamin D metabolism When measured with c-terminal assay, it has been shown to be increased following burn. Progress ... [more ▼]

INTRODUCTION: Fibroblast growth factor 23 (FGF23) is a key regulator in phosphate and vitamin D metabolism When measured with c-terminal assay, it has been shown to be increased following burn. Progress in understanding FGF23 physiology has emphasized the importance of assessing the intact form of FGF23. METHODS: The present cohort study is a complementary analysis of a previously published work. Patients >18 years, admitted within 24h after injury with burn surface area (BSA) >10% were included. C-terminal (c-term) and intact (i) FGF23 assay were performed at admission and every week during 4 weeks of follow-up. Inflammation and iron status were assessed at the same time points. RESULTS: Twenty patients were initially included and 12 were followed until day 28. The c-term FGF23 tended to gradually increase during the 4 weeks of follow-up while iFGF23 was quite stable into normal ranges. Iron status showed a typical inflammatory profile. C-term FGF23 was significantly positively correlated with c-reactive protein (CRP) and negatively correlated with iron levels. iFGF23 was not correlated with CRP or iron. CONCLUSION: FGF23 status following burn is characterized by a dissociation between c-term FGF23 and iFGF23. The hypothesis of an increased cleavage may be raised. Respective role of inflammation and iron levels in such deregulation need to be specified. Both c-term and intact assays should be performed in further studies aiming to increase knowledge on FGF23 regulation and effects in burn patients. [less ▲]

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