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See detailIonospheric slab thickness - Analysis, modelling and monitoring
Stankov, Stanimir; Warnant, René ULg

in Advances in Space Research (2009), 44(10), 1295-1303

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See detailIonospheric slab thickness: analysis and monitoring applications
Stankov, Stanimir; Warnant, René ULg

in Proceedings of the 12th International Ionospheric Effects Symposium (IES2008) (2008, May)

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See detailThe Ionospheric Total Electron Content : Simulation of the measurement by the NEIGE/NETLANDER experiment
Cerisier, Jean-Claude; Warnant, René ULg; Morel, Laurent

Conference (2001)

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See detailIonospheric variability which degrades the precision of real time GNSS applications
Wautelet, Gilles ULg; Lejeune, Sandrine; Warnant, René ULg

Poster (2008, November 18)

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See detailIOT Overview: Optical Multi-Object Spectrographs
Schmidtobreick, L.; Bagnulo, S.; Jehin, Emmanuel ULg et al

in Kaufer, A. (Ed.) The 2007 ESO Instrument Calibration Workshop (2008)

We give an introduction to the several instruments that ESO operates and which are able to perform optical multi-object spectroscopy. We point out the standard ways of reducing these spectra, the problems ... [more ▼]

We give an introduction to the several instruments that ESO operates and which are able to perform optical multi-object spectroscopy. We point out the standard ways of reducing these spectra, the problems that occur, and the way we deal with them. A short introduction is given on how the quality control is performed. [less ▲]

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See detailThe Iowa Gambling Task in fMRI images.
Li, Xiang ULg; Lu, Z. L.; D'Argembeau, Arnaud ULg et al

in Human Brain Mapping (2010), 31

The Iowa Gambling Task (IGT) is a sensitive test for the detection of decision-making impairments in several neurological and psychiatric populations. Very few studies have employed the IGT in functional ... [more ▼]

The Iowa Gambling Task (IGT) is a sensitive test for the detection of decision-making impairments in several neurological and psychiatric populations. Very few studies have employed the IGT in functional magnetic resonance imaging (fMRI) investigations, in part, because the task is cognitively complex. Here we report a method for exploring brain activity using fMRI during performance of the IGT. Decision-making during the IGT was associated with activity in several brain regions in a group of healthy individuals. The activated regions were consistent with the neural circuitry hypothesized to underlie somatic marker activation and decision-making. Specifically, a neural circuitry involving the dorsolateral prefrontal cortex (for working memory), the insula and posterior cingulate cortex (for representations of emotional states), the mesial orbitofrontal and ventromedial prefrontal cortex (for coupling the two previous processes), the ventral striatum and anterior cingulate/SMA (supplementary motor area) for implementing behavioral decisions was engaged. These results have implications for using the IGT to study abnormal mechanisms of decision making in a variety of clinical populations. Hum Brain Mapp, 2009. (c) 2009 Wiley-Liss, Inc. [less ▲]

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See detailIP Geolocation Databases: Unreliable?
Poese, Ingmar; Uhlig, Steve; Kaafar, Mohamed Ali et al

in Computer Communication Review (2011), 41(2), 53-56

The most widely used technique for IP geolocation con- sists in building a database to keep the mapping between IP blocks and a geographic location. Several databases are available and are frequently used ... [more ▼]

The most widely used technique for IP geolocation con- sists in building a database to keep the mapping between IP blocks and a geographic location. Several databases are available and are frequently used by many services and web sites in the Internet. Contrary to widespread belief, geolo- cation databases are far from being as reliable as they claim. In this paper, we conduct a comparison of several current geolocation databases -both commercial and free- to have an insight of the limitations in their usability. First, the vast majority of entries in the databases refer only to a few popular countries (e.g., U.S.). This creates an imbalance in the representation of countries across the IP blocks of the databases. Second, these entries do not re- flect the original allocation of IP blocks, nor BGP announce- ments. In addition, we quantify the accuracy of geolocation databases on a large European ISP based on ground truth information. This is the first study using a ground truth show- ing that the overly fine granularity of database entries makes their accuracy worse, not better. Geolocation databases can claim country-level accuracy, but certainly not city-level. [less ▲]

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See detailIP Sustainable pig production : economic aspects
Berti, Fabio ULg

Scientific conference (2011)

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See detailIpad et Kindle sont sur un bateau
Habrand, Tanguy ULg

Article for general public (2011)

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See detailIPHAS and the symbiotic stars . II. New discoveries and a sample of the most common mimics
Corradi, R. L. M.; Valentini, Marica ULg; Munari, U. et al

in Astronomy and Astrophysics (2010), 509

Context. Knowledge of the total population of symbiotic stars in the Galaxy is important for understanding basic aspects of stellar evolution in interacting binaries and the relevance of this class of ... [more ▼]

Context. Knowledge of the total population of symbiotic stars in the Galaxy is important for understanding basic aspects of stellar evolution in interacting binaries and the relevance of this class of objects in the formation of supernovae of type Ia. <BR /> Aims: In a previous paper, we presented the selection criteria needed to search for symbiotic stars in IPHAS, the INT Hα survey of the Northern Galactic plane. IPHAS gives us the opportunity to make a systematic, complete search for symbiotic stars in a magnitude-limited volume. <BR /> Methods: Follow-up spectroscopy at different telescopes worldwide of a sample of sixty two symbiotic star candidates is presented. <BR /> Results: Seven out of nineteen S-type candidates observed spectroscopically are confirmed to be genuine symbiotic stars. The spectral type of their red giant components, as well as reddening and distance, were computed by modelling the spectra. Only one new D-type symbiotic system, out of forty-three candidates observed, was found. This was as expected (see discussion in our paper on the selection criteria). The object shows evidence for a high density outflow expanding at a speed ≥65 km s[SUP]-1[/SUP]. Most of the other candidates are lightly reddened classical T Tauri stars and more highly reddened young stellar objects that may be either more massive young stars of HAeBe type or classical Be stars. In addition, a few notable objects have been found, such as three new Wolf-Rayet stars and two relatively high-luminosity evolved massive stars. We also found a helium-rich source, possibly a dense ejecta hiding a WR star, which is surrounded by a large ionized nebula. <BR /> Conclusions: These spectroscopic data allow us to refine the selection criteria for symbiotic stars in the IPHAS survey and, more generally, to better understand the behaviour of different Hα emitters in the IPHAS and 2MASS colour-colour diagrams. Based on observations obtained at; the 2.6 m Nordic Optical Telescope operated by NOTSA; the 2.5 m INT and 4.2 m WHT telescopes of the Isaac Newton Group of Telescopes in the Spanish Observatorio del Roque de Los Muchachos of the Instituto de Astrofísica de Canarias; the 2.3 m ANU telescope at Siding Spring Observatory, Australia; the Asiago 1.82 m telescope of the INAF Astronomical Observatory of Padova, Italy; and the 2.1 m telescope at San Pedro Martir, Mexico. Some of the INT spectra incorporated into this paper were obtained as part of a CCI International Time Programme awarded to the IPHAS collaboration. This publication makes use of data products from the Two Micron All Sky Survey, which is a joint project of the University of Massachusetts and the Infrared Processing and Analysis Center/California Institute of Technology, funded by the National Aeronautics and Space Administration and the National Science Foundation. This research has also made use of the SIMBAD database, operated at CDS, Strasbourg, France. [less ▲]

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See detailIpilimumab induces simultaneous regression of melanocytic naevi and melanoma metastases
LIBON, Florence ULg; ARRESE ESTRADA, Jorge ULg; RORIVET, A. et al

in Clinical & Experimental Dermatology (2012), (4452), 1-4

Background : Ipilimumab blocks cytotoxic T-lymphocyte-associated antigen (CTLA)-4, potentiating the antimelanoma T-cell host reponse. Ipilimumab has been shown to improve overall survival in patients with ... [more ▼]

Background : Ipilimumab blocks cytotoxic T-lymphocyte-associated antigen (CTLA)-4, potentiating the antimelanoma T-cell host reponse. Ipilimumab has been shown to improve overall survival in patients with previously treated metastatic melanoma. CTLA-4 antibodies generate immune responses to the melanoma-associated antigens Melan-A, NY-ESO-1 and glycoprotein (gp) 100 in metastatic melanoma. Digital epiluminescence microscopy (DELM) is a noninvasive method permitting the monitoring of the morphology of melanocytic lesions over time. Observation : A 50-year-old man with metastatic melanoma received four ipilimumab injections after failure of dacarbazine chemotherapy. Positron emission tomography revealed regression of pulmonary metastases, and simultaneously, DELM showed regression of several melanocytic naevi. On histological examination of the regressing naevi, prominent CD8+, CD4+ and CD45R0 lichenoid lymphohistiocytic infiltrates were seen, whereas nonregressing naevi were almost free of inflammatory infiltrate. Conclusion : Expression of melanoma-associated antigens in benign melanocytic naevi may explain the induction of naevus regression by ipilimumab. DELM could represent a valuable noninvasive method to monitor ipilimumab efficacy. [less ▲]

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See detailIpilimumab, a promising immunotherapy with increased overall survival in metastatic melanoma?
PIERARD, Gérald ULg; Aubin, Francois; Humbert, Philippe

in Dermatology Research and Practice (2012), 2012

Malignant melanoma (MM) is one of the most aggressive skin cancer. The therapeutic options remain limited for advanced MM, and those directed to the neoplastic cells have not brought major survival ... [more ▼]

Malignant melanoma (MM) is one of the most aggressive skin cancer. The therapeutic options remain limited for advanced MM, and those directed to the neoplastic cells have not brought major survival advantage so far. Immunotherapy is another targeted option. Ipilimumab, a monoclonal antibody directed to CTLA-4 present on cytotoxic T cells boosts immunity, particularly its anti-MM activity. Under treatment, the overall survival of patients with MM metastases is moderately but significantly increased. The immuno-related adverse effects may be severe and life threatening. [less ▲]

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See detailIPM in Asia - A review of existing projects in the Philippines and Indonesia
Wynn, Nigel R.; Schiffers, Bruno ULg; Seghers, N. et al

in Agro-Chemicals News in Brief (1997), XX(2), 1-18

Integrated Pest Management means a pest management system that, in the context of the associated environment and the population dynamics of the pest species, utilizes ail suitable techniques and methods ... [more ▼]

Integrated Pest Management means a pest management system that, in the context of the associated environment and the population dynamics of the pest species, utilizes ail suitable techniques and methods in as compatible a manner as possible and maintains the pest populations at levels below those causing economically unacceptable damage or 1055. FAO-Code- of Conduct 1984. [less ▲]

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See detailIpNose : Electronic nose for remote bad odour monitoring system in landfill sites.
Perera, A.; Pardo, T.; Sundi, T. et al

in Proceedings of the 8th conference Eurodeur (2001)

Electronic noses are intelligent instruments that are able to classify and quantify different gas/odours. Here we suggest the integration of a small form factor computer inside the electronic nose. This ... [more ▼]

Electronic noses are intelligent instruments that are able to classify and quantify different gas/odours. Here we suggest the integration of a small form factor computer inside the electronic nose. This concept allows us to easily provide remote connectivity, large data storage and complex signal processing. The evolution of this technology will permit distributed sensing with applications to agriculture and environment. Proposed instrument allows incoming connections for remote control of bad odours in landfill sites. Preliminary approach to this application using commercial sensors and mixture model pattern recognition scheme is exposed. [less ▲]

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See detailLes IPP au très long cours: le problème est-il uniquement économique?
Vanmeerbeek, Marc ULg; Louis, Edouard ULg

in Revue Médicale de Liège (2006), 61(5-6), 483-7

Proton pump inhibitors are among the most prescribed drugs in Belgium, due to the high prevalence of gastrooesophageal reflux disease and significant impairment of health-related well-being. Short-term ... [more ▼]

Proton pump inhibitors are among the most prescribed drugs in Belgium, due to the high prevalence of gastrooesophageal reflux disease and significant impairment of health-related well-being. Short-term and long-term efficacy is superior to that of H2-receptor antagonists. Long-term safety is established. Empirical short-term treatment of symptomatic patients under 50 years of age without alarm signs is acceptable, but endoscopic investigation should always be performed before starting a long-term treatment. Doses for management of low-grade oesophagitis may be tailored to the patient's response. Continuous maintenance of full-dose is recommended for high grade oesophagitis. Surgical alternative is to be discussed with patients. Efficacy and mean cost for insurance plans are comparable. Endoscopic procedures are not yet sufficiently evaluated to be considered. Simple lifestyle advice is still useful. The burden of proton pump inhibitors cost is acceptable if they are prescribed at adequate doses. Cost-effective drugs should be chosen first. [less ▲]

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See detailIpriflavone has no effect on bone metabolism and causes lymphopenia in osteopenic women
Alexandersen, P; Toussaint, A; Reginster, Jean-Yves ULg et al

in Journal of Bone and Mineral Research (2000), 15(S1), 198

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See detailIpriflavone in prevention and treatment of postmenopausal and senile osteoporosis
Reginster, Jean-Yves ULg

in Osteoporosis News (1996), 4

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See detailIpriflavone in the treatment of postmenopausal osteoporosis: a randomized controlled trial.
Alexandersen, P; Toussaint, André ULg; Christiansen, C et al

in JAMA : Journal of the American Medical Association (2001), 285(11), 1482-8

CONTEXT: Data on the efficacy and safety of ipriflavone for prevention of postmenopausal bone loss are conflicting. OBJECTIVES: To investigate the effect of oral ipriflavone on prevention of ... [more ▼]

CONTEXT: Data on the efficacy and safety of ipriflavone for prevention of postmenopausal bone loss are conflicting. OBJECTIVES: To investigate the effect of oral ipriflavone on prevention of postmenopausal bone loss and to assess the safety profile of long-term treatment with ipriflavone in postmenopausal osteoporotic women. DESIGN AND SETTING: Prospective, randomized, double-blind, placebo-controlled, 4-year study conducted in 4 centers in Belgium, Denmark, and Italy from August 1994 to July 1998. PARTICIPANTS: Four hundred seventy-four postmenopausal white women, aged 45 to 75 years, with bone mineral densities (BMDs) of less than 0.86 g/cm(2). INTERVENTIONS: Patients were randomly assigned to receive ipriflavone, 200 mg 3 times per day (n = 234), or placebo (n = 240); all received 500 mg/d of calcium. MAIN OUTCOME MEASURES: Efficacy measures included spine, hip, and forearm BMD and biochemical markers of bone resorption (urinary hydroxyproline corrected for creatinine and urinary CrossLaps [Osteometer Biotech, Herlev, Denmark] corrected for creatinine), assessed every 6 months. Laboratory safety measures and adverse events were recorded every 3 months. RESULTS: Based on intent-to-treat analysis, after 36 months of treatment, the annual percentage change from baseline in BMD of the lumbar spine for ipriflavone vs placebo (0.1% [95% confidence interval (CI), -7.9% to 8.1%] vs 0.8% [95% CI, -9.1% to 10.7%]; P =.14), or in any of the other sites measured, did not differ significantly between groups. The response in biochemical markers was also similar between groups (eg, for hydroxyproline corrected for creatinine, 20.13 mg/g [95% CI, 18.85-21.41 mg/g] vs 20.67 mg/g [95% CI, 19.41-21.92 mg/g]; P =.96); urinary CrossLaps corrected for creatinine, 268 mg/mol (95% CI, 249-288 mg/mol) vs 268 mg/mol (95% CI, 254-282 mg/mol); P =.81. The number of women with new vertebral fracture was identical or nearly so in the 2 groups at all time points. Lymphocyte concentrations decreased significantly (500/microL (0.5 x 10(9)/L]) in women treated with ipriflavone. Thirty-one women (13.2%) in the ipriflavone group developed subclinical lymphocytopenia, of whom 29 developed it during ipriflavone treatment. Of these, 15 (52%) of 29 had recovered spontaneously by 1 year and 22 (81%) of 29 by 2 years. CONCLUSIONS: Our data indicate that ipriflavone does not prevent bone loss or affect biochemical markers of bone metabolism. Additionally, ipriflavone induces lymphocytopenia in a significant number of women. [less ▲]

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See detailIpriflavone inhibits interleukin-I stimulated neutral metalloprotease synthesis in human chondrocytes cultivated in clusters
Franchimont, P; Bassleer, C; Henrotin, Yves ULg et al

in Osteoarthritis and Cartilage (1994), 2(S1), 52

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See detailIpriflavone: Pharmacological Properties and Usefulness in Postmenopausal Osteoporosis
Reginster, Jean-Yves ULg

in Bone and Mineral (1993), 23(3), 223-32

Ipriflavone (IP) is an isoflavone derivative available in several countries for investigational and/or therapeutic use. Inhibition of bone resorption was demonstrated in several models, both in vitro and ... [more ▼]

Ipriflavone (IP) is an isoflavone derivative available in several countries for investigational and/or therapeutic use. Inhibition of bone resorption was demonstrated in several models, both in vitro and in vivo for IP and its metabolites. Their mechanisms of action on bone are not yet fully elucidated but some of them are widely accepted. IP does not possess, per se, any estrogenic activity. It appears that IP-related inhibition of bone resorption might be mediated by an indirect effect on osteoclast and related to an inhibition of recruitment and/or differentiation of pre-osteoclast, maybe through a modulation of osteoblast response to PTH. Clinical studies in Paget's disease of bone or primary hyperparathyroidism have confirmed preferential inhibition of bone resorption suggesting a clinical interest in postmenopausal osteoporosis. Preliminary (1 year) results of double blind placebo controlled studies designed in postmenopausal and senile osteoporosis confirm a reduction in bone turnover rate in patients treated with 600 mg/day of IP, resulting in a significant bone-sparing effect both at lumbar and radial levels. All clinical and pharmacological trials confirm a very good tolerance of IP with a frequency of adverse reactions equal to that observed during administration of a placebo. Providing ongoing studies will confirm the actual promising preliminary results, IP seems a very interesting new non hormonal approach for prevention and treatment of postmenopausal and senile osteoporosis. [less ▲]

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