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See detailGonadal pathology and tumor risk in relation to clinical characteristics in patients with 45,X/46,XY mosaicism
Cools, M.; Pleskacova, J.; Stoop, H. et al

in Journal of Clinical Endocrinology and Metabolism (2011), 96(7), 1171-1180

Detailed reference viewed: 20 (2 ULg)
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See detailGonadal-Independent Developmental Changes in Activation of N-Methyl-D-Aspartate Receptors Involved in Gonadotropin-Releasing Hormone Secretion
Bourguignon, Jean-Pierre ULg; Gerard, Arlette ULg; Alvarez Gonzalez, Maria-Luz ULg et al

in Neuroendocrinology (1992), 55(6), 634-41

Using hypothalamic explants of male rats, we have shown that the N-methyl-D-aspartate (NMDA) receptors involved in a stimulatory control of gonadotropin-releasing hormone (GnRH) secretion were transiently ... [more ▼]

Using hypothalamic explants of male rats, we have shown that the N-methyl-D-aspartate (NMDA) receptors involved in a stimulatory control of gonadotropin-releasing hormone (GnRH) secretion were transiently activated at 25 days around the time of onset of puberty. This was evidenced by studying the dose-related inhibition of veratridine-induced GnRH secretion by MK-801, a use dependent antagonist of NMDA receptors. An increase in sensitivity of GnRH secretion to the inhibitory effect of MK-801 was used as a marker of increased activation of NMDA receptors involved in stimulation of GnRH secretion. Here, we report on data obtained in intact and castrated rats at different ages. The aim was to determine whether the absence of gonads would affect the developmental changes in activation of NMDA receptors that we described recently. In pubertal (50-day-old) rats, orchidectomy resulted in an activation of NMDA receptors which was nonsignificant after 4 days but significant after 13 days. In prepubertal rats orchidectomized at 5 or 10 days and studied 10 days later, the NMDA receptors involved in GnRH secretion were also more activated than in intact animals. Using explants of intact and castrated animals, a similar increase in activation of NMDA receptors was observed between 15 and 25 days of age, a period preceding onset of puberty. Subsequently, between 25 and 50 days, a reduction in NMDA receptor activation was seen. This decrease was observed in intact rats showing normal sexual development and in castrated rats as well.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

Detailed reference viewed: 16 (1 ULg)
See detailLes gonadotrophinomes
Beckers, Albert ULg

Scientific conference (1988, May)

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See detailGonadotropin Releasing Hormone Inhibitory Autofeedback by Subproducts Antagonist at N-Methyl-D-Aspartate Receptors: A Model of Autocrine Regulation of Peptide Secretion
Bourguignon, Jean-Pierre ULg; Alvarez Gonzalez, Maria-Luz ULg; Gerard, Arlette ULg et al

in Endocrinology (1994), 134(3), 1589-92

The secretion of Gonadotropin-releasing Hormone (GnRH) involves activation of N-methyl-D-aspartate (NMDA) receptors. Here, we show that pulsatile GnRH secretion from hypothalamic explants is suppressed by ... [more ▼]

The secretion of Gonadotropin-releasing Hormone (GnRH) involves activation of N-methyl-D-aspartate (NMDA) receptors. Here, we show that pulsatile GnRH secretion from hypothalamic explants is suppressed by 1-5GnRH, an endogenous breakdown product of GnRH, while 2-10GnRH has no effect. GnRH secretion evoked by NMDA is selectively inhibited by 1-5GnRH and this effect is similar to that of AP-5, a competitive antagonist at NMDA receptors. In addition, 1-5GnRH accounts for a dose-related inhibition of tritiated glutamate binding to hypothalamic membrane preparations. Using GnRH secretion as a model of NMDA-receptor controlled system, the effect of different peptides has been studied. Growth Hormone Releasing Factor (GRF), Insulin-like Growth Factor-I (IGF-I) and Proinsulin result in inhibition of GnRH secretion. Bioactive subproducts of those peptides (1-29GRF, 4-701GF-I and insulin) do not show any effect, suggesting that their classical receptors are not involved. In contrast, GnRH secretion is inhibited by other subproducts (1-37GRF, 1-31GF-I and C-peptide) all terminating in a glutamate residue. These subproducts selectively suppress the NMDA-evoked secretion of GnRH. Protease inhibitors prevent the inhibitory effects of IGF-I on GnRH secretion. This, breakdown products of different peptide hormones are possible endogenous antagonists at NMDA receptors. This effect could account for an autocrine or paracrine limitation of NMDA-receptor-mediated secretion of peptides. [less ▲]

Detailed reference viewed: 28 (4 ULg)
See detailGonadotropin secreting tumors
Beckers, Albert ULg; Ciccarelli, A.; Valdes Socin, Hernan Gonzalo ULg et al

in The Encyclopedia of Endocrinology and Endocrine Diseases (2004)

Detailed reference viewed: 27 (1 ULg)
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See detailGonadotropin secretion in the bovine : localization of LH and FSH in pituitaries by electron microscopy.
Bastings, E.; Beckers, Albert ULg; Reznik, M. et al

in Journal of Endocrinological Investigation (1990)

Detailed reference viewed: 5 (0 ULg)
See detailGonarthrose: intérêt de l'évaluation isocinétique
Croisier, Jean-Louis ULg; Henrotin, Yves ULg; Dumont, R. et al

in KINE 2000 (1998, December), 9(98/5), 90

Detailed reference viewed: 60 (6 ULg)
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See detailGoncourt des lycéens et roman adressé à la jeunesse: quels points communs ?
Delbrassine, Daniel ULg

in Lecture Jeune (2011), 137

Comparaison thématique et formelle entre les 6 derniers romans primés au Goncourt des lycéens français et le roman adressé aux adolescents

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See detailGondwanan Palaeozoic plant spores: A review
Steemans, Philippe ULg; Gerrienne, Philippe ULg

Conference (2016, April 15)

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See detailGoniocysts, goniocystangia and Opegrapha lambinonii and related species
Sérusiaux, Emmanuël ULg

in Lichenologist (1985), 17

Detailed reference viewed: 10 (0 ULg)
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See detailGood interpretation of a biological result: generality and specificity to Nephrology
CAVALIER, Etienne ULg

in DELANAYE, Pierre (Ed.) Clinical Chemistry and Nephrology: the essential link (2012)

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See detailGood Laboratory Practice: How to avoid pitfalls of quantitative analysis
Ziemons, Eric ULg; Hubert, Philippe ULg

Learning material (2009)

The objective of a quantitative analytical method is to be able to quantify accurately as possible each unknown that the laboratory will have to determine according to the analytical procedure. The ... [more ▼]

The objective of a quantitative analytical method is to be able to quantify accurately as possible each unknown that the laboratory will have to determine according to the analytical procedure. The analytical procedure refers to the way of performing the analysis. It should describe in detail the steps necessary to perform each analytical test. This may included but is not limited to samples, reference standards and reagents preparation: weighing, quantitative transfer and dispensing an aliquot. The choice of the laboratory material and also the way to use it have a dramatic influence on the accuracy of an analytical method. [less ▲]

Detailed reference viewed: 64 (2 ULg)
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See detailGood OA practices from Funders: FRS/FNRS, Belgium
Rentier, Bernard ULg

Scientific conference (2015, October 29)

The FRS/FNRS is the major funding agency for basic research in the French-speaking Community of Belgium. In 2013, it passed an internal regulation mandating, for researchers receiving salaries and/or ... [more ▼]

The FRS/FNRS is the major funding agency for basic research in the French-speaking Community of Belgium. In 2013, it passed an internal regulation mandating, for researchers receiving salaries and/or grant money fron the Fund, the deposit in their institutional OA repository of all their scientific production in full text. The FRS/FNRS supports APCs, up to 500 € per article, but not in "hybrid" journals. [less ▲]

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See detailGood practices from Universities: University of Liège, Belgium - Impact of Open Archives on Research Communication Efficiency : The ORBi Experience
Rentier, Bernard ULg

Scientific conference (2015, October 30)

ORBi, the institutional repository at the University of Liège (ULg), Belgium, is currently the most successful "green OA" tool, with a compliance rate close to 90%. This is due to a strongly enforced ... [more ▼]

ORBi, the institutional repository at the University of Liège (ULg), Belgium, is currently the most successful "green OA" tool, with a compliance rate close to 90%. This is due to a strongly enforced institutional mandate which has progressively but quickly led authors to realise all the benefits they could draw from it. A September 2015 survey has demonstrated the popularity of ORBi among the ULg research community. [less ▲]

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See detailGood prognosis factors after a platelet rich plasma (PRP) injection for tendinopathies ?
Kaux, Jean-François ULg; Sancerne, Audrey; Libertiaux, Vincent ULg

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(suppl. 1 No. 2), 251

Introduction : Platelet-rich plasma injections are a recent treatment for chronic tendinopathies. However, this theraeutic remains controversed in litterature. Up to now, there is no prognosis factors ... [more ▼]

Introduction : Platelet-rich plasma injections are a recent treatment for chronic tendinopathies. However, this theraeutic remains controversed in litterature. Up to now, there is no prognosis factors identified to predict a good evolution after injection of PRP. Purpose: The aims of this study were to evaluate the effect of PRP injection followed by a standardized reeducation protocol among patients suffering from different tendinopathies and to determine the good prognosis factors, if any. Methods : 51 patients suffering from different tendinopathies and refractory to conventional physiotherapy were treated with a PRP injection. Prior to the injection, a blood sample was drawn and some biological parameters (glycemia, cholesterol level, …). A pain assessment was then made using a visual analog scale (VAS) and a pressure algometer. The same assessment was carried out after 6 weeks and 12 weeks when possible. Results : There is an overall significant improvement VAS score at the end of the 12 weeks follow- up. However, no correlation was found between the evolution of the clinical scores and the biological parameters measured. Discussion and Conclusions : A PRP injection followed by a program of eccentric rehabilitation positively affects the algo-functional scores of patients with tendinopathie who were refractory to conventional physiotherapy, whatever their initial biological parameters. [less ▲]

Detailed reference viewed: 64 (4 ULg)
See detailThe Good, The Bad and the Ugly: integrating multiple frames in Flanders and Wallonia air policies by using the Delphi method
Fallon, Catherine ULg; Hendrickx, Kim ULg; Vanhaeren, Stéphanie ULg

Conference (2010, June 21)

A new European frame has developed stepwise to manage the health effect of air pollution from particulate matter (PM 10 and PM 2,5), backed by an international body of scientific knowledge and OMS reports ... [more ▼]

A new European frame has developed stepwise to manage the health effect of air pollution from particulate matter (PM 10 and PM 2,5), backed by an international body of scientific knowledge and OMS reports. The European Union CAFE Directive (2008) leaves the Member States with an important margin to translate the air quality objectives into action plans. In Belgium this policy is entirely left to the regions which developed different frames and decisional spaces. Belgium is a pollution 'hot spot' because of the variety of pollution sources it is faced with (traffic density, industrial density, transboundary pollution). As such, it provides an interesting ground for comparative research. We conducted a comparative research in the two largest Belgian regions and identified two decisional spaces that differ on a political, administrative and technical levels. Earlier research on risk management has pointed out that transversality, openness, and interdisciplinarity positively affect the quality of decision making under uncertainty. In that perspective, can specific tools help foster a transversal and integrative approach in air policy? In the Scope-project, a web-based tool using the Delphi method has been tested in the two regions. This allowed to put forward some hypotheses concerning the potential for transversality, interdisciplinary and openness in these different structures and decisional spaces. The results of the experiment and its potential for generalisation will be discussed at length. [less ▲]

Detailed reference viewed: 84 (18 ULg)
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See detailGoodness of fit testing and data set stability with respect to misclassification
Magis, David ULg

Conference (2004, October)

Detailed reference viewed: 9 (1 ULg)
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See detailGoodness-of-fit tests for censored regression based on artificial data points
González Manteiga, Wenceslao; Heuchenne, Cédric ULg; Sánchez Sellero, Cesar

Report (2008)

Detailed reference viewed: 74 (3 ULg)
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See detailGoodness-of-fit tests for the error distribution in nonparametric regression
Heuchenne, Cédric ULg; Van Keilegom, Ingrid

in Computational Statistics & Data Analysis (2010), 54

Detailed reference viewed: 49 (21 ULg)