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See detailImportance et dynamique du complexe parasitaire du cotonnier dans la région de Gandajika au Zaïre
Delhove, G.; Mergeai, Guy ULg; Mulamba, K.

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), (35), 379-387

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See detailImportance et rôle de l’investissement…
Choffray, Jean-Marie ULg

E-print/Working paper (2015)

Quelques observations et réflexions en réponse à une question qui m’est souvent posée sur l’importance et le rôle des investisseurs. Ces « Charognards », particulièrement visés au cours des périodes de ... [more ▼]

Quelques observations et réflexions en réponse à une question qui m’est souvent posée sur l’importance et le rôle des investisseurs. Ces « Charognards », particulièrement visés au cours des périodes de tension géopolitique, de populisme ou de débauche monétaire, semblables à celle que nous vivons aujourd’hui. Ma réponse en peu de mots : les investisseurs sont des défenseurs de la valeur du travail par temps calme et des vigies dans la tempête ! [less ▲]

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See detailImportance nutritionnelle du manioc et perspectives pour l’alimentation de base au Sénégal (synthèse bibliographique)
Diallo, Younoussa; Gueye, Momar Talla; Sakho, Mama et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2013), 17(4), 634-643

Cassava is one of the main plants and starchy roots grown in the world. In 2008, the total yield of cassava in West Africa represented 29% of the world production. However, in many West African countries ... [more ▼]

Cassava is one of the main plants and starchy roots grown in the world. In 2008, the total yield of cassava in West Africa represented 29% of the world production. However, in many West African countries such as Senegal, cassava is not used as a staple food. In fact, the processing techniques used for cassava are poorly known. In addition, the chemical composition of local cassava varieties has not yet been determined, nor has their toxicity been assessed. In 2004, showing an aggressive agricultural policy and revived interest, the Senegalese government launched a major program for intensifying the production of cassava for food security purposes. Cassava is an important source of calories and can be an interesting option for imported rice and wheat. Although many food products made from cassava are well known in the region, their use in the Senegalese diet is rare. Nevertheless, these cassava products are found as delicacies in some restaurants, and are consumed by the Senegalese and many other Africans. The objective of the present study is to demonstrate the nutritional value and the dietary possibilities of using cassava as a staple food in Senegal. [less ▲]

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See detailImportance of a Well-distributed Frequency of Measurements in the Senescence Monitoring of Winter Wheat and Yield Estimates
Kouadio, Louis; Djaby, Bakary ULg; El Jarroudi, Moussa ULg et al

in Journal of Agricultural Science and Technology (2012), 2

Theoretical frequencies of green area index (GAI) measurements were assessed in order to bring out the optimum frequencies for the monitoring of the senescence of winter wheat as well as the relationships ... [more ▼]

Theoretical frequencies of green area index (GAI) measurements were assessed in order to bring out the optimum frequencies for the monitoring of the senescence of winter wheat as well as the relationships between metrics which could be derived and the final grain yield. Several profiles of GAI decreasing curves were elaborated based on field measurements. Two functions, usually employed in green leaf area decreasing curves fitting (i.e., modified Gompertz and logistic functions) were then used to characterize the senescence phase and to calculate their metrics. These analyses showed that the two curve fitting functions satisfactorily described the senescence phase on frequencies of four to six GAI measurements, well distributed throughout a period of 30-35 days. The regression-based modeling showed that those involving metrics from logistic function (i.e., maximum value of GAI, green area duration and senescent rate) were more suitable than that of the modified Gompertz function for wheat yield estimates. Such results could be useful for studies at larger scales (involving remote sensing airplane or satellite data) and focused on the senescence in terms of optimum number of measurements and frequencies for developing models for yield estimates. [less ▲]

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See detailThe importance of accurate lymph node staging in early and locally advanced non-small cell lung cancer: An update on available techniques
Kim, E. S.; Bosquee, Léon ULg

in Journal of Thoracic Oncology (2007), 2(6, Suppl. S), 59-67

Medical oncologists are faced with multiple factors to consider when staging a patient with suspected or confirmed non-small cell lung cancer (NSCLC). Identifying pathological nodal (N2) disease is ... [more ▼]

Medical oncologists are faced with multiple factors to consider when staging a patient with suspected or confirmed non-small cell lung cancer (NSCLC). Identifying pathological nodal (N2) disease is, however, of great importance because its presence significantly affects outcomes and potential treatment strategies. Recent data supporting the use of adjuvant or neoadjuvant therapies in these patients suggests that every reasonable effort should be made to assess the lymph node status accurately in patients with clinical early stage disease as well as in those with clinically staged N2 disease who have undergone preoperative treatments. Newer procedures such as integrated positron emission tomography computed tomography and esophageal or endobronchial endoscopic ultrasound with fine needle aspiration are mininially invasive techniques that may enhance the accuracy of mediastinal staging, traditionally devoted to mediastinoscopy. As their availability widens, they are likely to become an important part of staging and treatment paradigms. Intraoperatively, a growing body of evidence Suggests that lymph node dissection can be performed safely, and should replace sampling as a more effective means of identifying unsuspected N2 disease. This paper will review the current literature on staging NSCLC with regard to the detection of I nodal disease through preoperative staging of the mediastinum, the use of intraoperative lymph node sampling or dissection at the time of resection, and procedures for use in restaging patients with clinical stage IIIA N2 disease who have undergone preoperative chemotherapy (with or without radiotherapy). [less ▲]

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See detailImportance of acyl-coA oxidases in beta-decalactone production by Yarrowia lipolytica
Waché, Y.; Aguedo, Mario ULg; Wang, H.J. et al

in Abstracts of Papers of the 219th ACS national meeting (2000, March)

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See detailImportance of albumen during embryonic development in avian species, with emphasis on domestic chicken
Willems, E.; Decuypere, E.; Buyse, J. et al

in World's Poultry Science Journal (2014), 70

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See detailThe importance of albumen-proteins during embryonic development of layer-type chickens on quality of eggs laying in adult life
Willems, Els; Wang, Yufeng; Willemsen, Hilke et al

Scientific conference (2012)

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See detailImportance of alfacalcidol in clinical conditions characterized by high rate of bone loss
Reginster, Jean-Yves ULg; Lecart, M. P.; Richy, F.

in Journal of Rheumatology (2005), 32(Suppl. 76), 21-25

In postmenopausal osteoporosis, the administration of alfacalcidol to women resulted in an increase in trabecular bone mineral density (BMD), prevention of cortical bone loss, and a significant reduction ... [more ▼]

In postmenopausal osteoporosis, the administration of alfacalcidol to women resulted in an increase in trabecular bone mineral density (BMD), prevention of cortical bone loss, and a significant reduction in the incidence of further vertebral fractures. There is now robust evidence that alfacalcidol may be particularly active in conditions characterized by an increased rate of bone loss. Alfacalcidol 1 microg/day fully prevented vertebral bone loss over 3 years in women after the first year of menopause. In a large cohort of individuals starting treatment with high dose corticosteroid (CS, 46.6 mg equivalent prednisolone per day), the spinal bone loss observed in untreated patients was fully prevented by administration of 1 microg/day alfacalcidol. In patients with established CS-induced osteoporosis, with or without prevalent vertebral fractures, 1 microg/day of alfacalcidol, given for 3 years, increased lumbar spine density, reduced back pain, and showed a significant reduction in the rate of new vertebral fractures, compared to native vitamin D. In cardiac transplant recipients, alfacalcidol and calcium reduced spinal and femoral bone loss, compared to a control group treated with etidronate and calcium. Alfacalcidol-treated patients experienced fewer new vertebral fractures over the 2-year followup. When alfacalcidol and vitamin D3 were compared in elderly women with radiologic evidence of vertebral fracture, fractional calcium absorption was increased after 3 months with alfacalcidol but was unchanged with vitamin D3. In a recent metaanalysis of 14 studies of native vitamin D and 19 studies of D-hormone analogs (alfacalcidol and calcitriol), the D-analogs exerted a higher preventive effect on bone loss and fracture rates in patients with no exposure to CS. In head-to-head studies comparing D-analogs and native vitamin D in patients receiving CS, this metaanalysis identified significant effects favoring D-analogs for femoral neck BMD and spinal fractures. In conclusion, improvement in bone turnover, increase in BMD, and reduction in fracture rates have been described during alfacalcidol treatment in situations characterized by a high rate of bone loss, including CS-induced osteoporosis, early postmenopausal bone loss, and organ transplant. Compared to plain vitamin D, alfacalcidol exerts higher bone-protective effects, thus allowing the doses to be minimized and lowering the risk of adverse effects, including hypercalcemia. [less ▲]

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See detailThe Importance of Awareness for Veterinarians Involved in Cattle Tuberculosis Skin Testing
Humblet, Marie-France ULg; Moyen, Jean-Louis; Bardoux, Patrick et al

in Transboundary and Emerging Diseases (2011)

France is currently facing a re-emergence of bovine tuberculosis in several regions. To assess the knowledge of veterinary field practitioners concerning skin testing, a questionnaire-based methodology ... [more ▼]

France is currently facing a re-emergence of bovine tuberculosis in several regions. To assess the knowledge of veterinary field practitioners concerning skin testing, a questionnaire-based methodology developed in Belgium was adapted to the context of the French department of Dordogne. The veterinarians involved in herds skin testing were solicited to participate to the survey (N = 94), through an anonymous postal questionnaire including items related to each step of the skin test procedure. Each item of the questionnaire was allotted a compliance score by 5 experts in the field of bovine tuberculosis (0, 1 or 2 a correct, acceptable and unacceptable answer respectively). These scores were balanced over 30 criteria according to their potential impact on the non-detection of reactors, on the basis of 11 experts’ opinion. A global score was calculated for each participating veterinarian. In addition, the Departmental sanitary authorities held meetings in December 2005 and June 2006 to make the veterinarians aware of the importance of correctly performing the skin test. The participants to the study were asked to fill in the questionnaire in duplicate, one related to their practices before the meeting, and the other one focusing on their practices after the meeting. A comparison of both situations was carried out (pre- and post-awareness meeting), as well as a comparison with the Belgian situation, arbitrarily selected as reference for the methodology. The participation was representative and reached a 23.4% rate. A significant difference was noticed between the mean global score reached before and after the meeting. These results show the usefulness of an appropriate awareness campaign of veterinarians in relation with skin testing and the importance of frequently holding awareness meetings in areas remaining confronted with bovine tuberculosis problems. It also highlights the interest of a structured auto-assessment process of veterinary practices [less ▲]

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See detailThe importance of being small
Tharakan, Joseph ULg

Conference (1998, December)

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See detailThe importance of being small
Tharakan, Joseph ULg; Thisse, Jacques

in Regional Science & Urban Economics (2002), 32

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See detailThe importance of being small
Tharakan, Joseph ULg

Conference (1999, April)

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See detailThe importance of carbonic anhydrase II in red blood cells during exposure of chicken embryos to CO2.
Everaert, Nadia ULg; Willemsen, H.; Hulikova, A. et al

in Respiratory physiology & neurobiology (2010), 172(3), 154-61

The importance of carbonic anhydrase (CA) during exposure of chicken embryos to CO(2) during the second half of incubation was investigated. The protein abundance and activity of CAII in erythrocytes was ... [more ▼]

The importance of carbonic anhydrase (CA) during exposure of chicken embryos to CO(2) during the second half of incubation was investigated. The protein abundance and activity of CAII in erythrocytes was significantly higher in CO(2)-exposed embryos compared to normal conditions. Daily injections of acetazolamide (ATZ), an inhibitor of CA, increased blood P(CO2) and decreased blood pH in both control and CO(2)-incubated embryos. ATZ increased blood bicarbonate concentration in embryos exposed to normal atmosphere and in day-12 embryos exposed to high CO(2). The tendency of an increased blood potassium concentration in ATZ-injected embryos under standard atmospheric conditions might indicate that protons were exchanged with intracellular potassium. However, there was no evidence for such an exchange in CO(2)-incubated ATZ-treated embryos. This study shows for the first time that chicken embryos adapt to CO(2) during the second half of incubation by increasing CAII protein expression and function in red blood cells. This response may serve to "buffer" elevated CO(2) levels. [less ▲]

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See detailImportance of Cell Kinetics Rhythmicity for the Control of Cell Proliferation and Carcinogenesis in Rat Liver (Review)
Barbason, Hervé ULg; Herens, Christian ULg; Robaye, B. et al

in In Vivo (Athens, Greece) (1995), 9(6, Nov-Dec), 539-48

The circadian control of cell Proliferation and Differentiation has been studied principally in rat liver. The comparison between the differentiation by hepatic enzymes and the division by the cell cycle ... [more ▼]

The circadian control of cell Proliferation and Differentiation has been studied principally in rat liver. The comparison between the differentiation by hepatic enzymes and the division by the cell cycle under various experimental conditions (postnatal maturation, regeneration after partial hepatectomy, adrenalectomy, corticosterone treatments etc.) leads to the following conclusions: Under physiological conditions, proliferation and differentiation activities present a mutually exclusive relationship with a specific circadian rhythm. For both functions, the circadian variation of corticosterone plays the role of synchronizer, each evening (peak) it induces the synthesis of tissue specific enzymes in G0 cells and simultaneously inhibits the DNA synthesis in cycling cells. The same parameters have been studied during the different stages of hepatocarcinogenesis induced by Diethylnitrosamine (DEN). After initiation alone, (DEN for 2 weeks) circadian control is unchanged and precancerous cells are not able to reach malignancy. Promotion (DEN for 6 weeks) consists of disturbing the circadian synchronization to liberate the selective growth of initiated precancerous cells. This proliferation advantage favours the accumulation of chromosomal aberrations including those implicated in malignant transformation: i.e. activation of oncogenes or inhibition of antioncogenes. [less ▲]

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See detailImportance of clean-up for comparison of TEQ-values obtained by CALUX and chemo-analysis
Van Wouwe, N.; Windal, I.; Vanderperren, H. et al

in Talanta (2004), 63(5), 1269-1272

This paper presents Chemically Activated LUciferine gene eXpression (CALUX) TEQ-values obtained for nine plasma samples following two different purification procedures, one of them involving fractionation ... [more ▼]

This paper presents Chemically Activated LUciferine gene eXpression (CALUX) TEQ-values obtained for nine plasma samples following two different purification procedures, one of them involving fractionation. CALUX results obtained for the dioxin (DX) and dioxin + PCB (DX + PCB) fractions were then compared to the GC-HRMS TEQ-values calculated for the 17 polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (17 PCDD/F) and 17 PCDD/F + 4 cPCB congeners, respectively. The overestimation of the CALUX (DX fraction) TEQ-values in comparison with the chemo-analyses of the 17 PCDD/F is mainly explained by the presence of other AhR agonists, like brominated compounds. Otherwise, the constancy of the CALUX (DX + PCB fraction) TEQ-value which compares to increasing the GC-HRMS (17 PCDD/F + 4 cPCB) TEQ results raises questions concerning (1) the significance of CALUX results obtained without fractionation as well as (2) the toxicological effect of a cocktail of contaminants on the human health. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]

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See detailImportance of concomitant local and systemic eosinophilia in uncontrolled asthma - Letter from the authors to editor
SCHLEICH, FLorence ULg; LOUIS, Renaud ULg

in The European respiratory journal (2014), 44(4), 1098-9

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See detailImportance of concomitant local and systemic eosinophilia in uncontrolled asthma.
SCHLEICH, FLorence ULg; Chevremont, Anne; Paulus, Virginie et al

in The European respiratory journal (2014), 44

Systemic and airway eosinophilia are recognised features of asthma. There are, however, patients who exhibit discordance between local and systemic eosinophilia. In this study, we sought to determine the ... [more ▼]

Systemic and airway eosinophilia are recognised features of asthma. There are, however, patients who exhibit discordance between local and systemic eosinophilia. In this study, we sought to determine the prevalence and characteristics of patients with concordant and discordant systemic and bronchial eosinophilia.We conducted a retrospective study on 508 asthmatics with successful sputum induction. We assessed the relationship between blood and sputum eosinophils by breaking down the population into four groups according to blood (>/=400 cells per mm3) and sputum (>/=3%) eosinophils. Then, we prospectively reassessed the link between eosinophils and asthma control (Asthma Control Questionnaire (ACQ)) and exacerbation rate in a new cohort of 250 matched asthmatics.In our retrospective cohort, asthmatics without eosinophilic inflammation were the largest group (49%). The group with isolated sputum eosinophilia (25%) was, compared with noneosinophilic asthma, associated with lower forced expiratory volume in 1 s (FEV1) and FEV1/forced vital capacity ratio and higher bronchial hyperresponsiveness and exhaled nitric oxide fraction (FeNO). Asthmatics exhibiting isolated systemic eosinophilia (7%) had similar characteristics as noneosinophilic asthmatics. The group with concordant systemic and airway eosinophilia (19%) showed remarkable male predominance, and had the lowest airway calibre, ACQ score and quality of life, and the highest bronchial hyperresponsiveness, FeNO and exacerbation rate. The prospective cohort confirmed the different subgroup proportions and the higher ACQ and exacerbation rates in cases of diffuse eosinophilia compared with noneosinophilic asthmatics.Concomitant systemic and bronchial eosinophilic inflammation contribute to poor asthma control. [less ▲]

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