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See detailInterférométrie de speckle en infrarouge thermique
Vandenrijt, Jean-François ULg; Georges, Marc ULg

in Résumés du Huitième colloque francophone Méthodes et Techniques Optiques pour l'Industrie (2007, November)

L’utilisation de l'interférométrie de speckle (ESPI) sur des objets opaques diffusants à une longueur d’onde de 10 µm en utilisant une caméra thermographique commerciale est présentée pour la première ... [more ▼]

L’utilisation de l'interférométrie de speckle (ESPI) sur des objets opaques diffusants à une longueur d’onde de 10 µm en utilisant une caméra thermographique commerciale est présentée pour la première fois à notre connaissance. L’idée d’utiliser une longueur d’onde plus grande que les longueurs d’onde visibles habituelles est de rendre les mesures de déplacements par des techniques holographiques moins sensibles aux perturbations extérieures. Dans cet article, nous discutons certains aspect particuliers dûs à l’accroissement de la longueur d’onde dans le domaine thermique de 10 µm. Nous montrons ensuite les résultats de mesures de rotations dans le plan d’une plaque métallique. Nous avons utilisé la technique du décalage de phase pour obtenir des mesures quantitatives qui sont corrélées par des mesures menées en parallèle avec un théodolite. [less ▲]

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See detailInterférométrie destructive: du sol à l’espace
Absil, Olivier ULg

Scientific conference (2005, March 22)

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See detailInterférométrie holographique avec cristaux photoréfractifs en régime impulsionnel. Développements et résultats préliminaires
Georges, Marc ULg; Pauliat, Gilles; Lemaire, Philippe et al

in Actes du 10e séminaire SFO/HOLO3 : Nouveaux moyens optiques pour l'industrie (1998, November)

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See detailInterférométrie holographique et de speckle en infrarouge thermique : développements actuels, applications et perspectives
Georges, Marc ULg

in Smigielski, P. (Ed.) Actes du Onzième colloque francophone Méthodes et Techniques Optiques pour l'Industrie (2010, November)

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See detailInterférométrie holographique photoréfractive : nouveaux développements et applications récentes
Thizy, Cédric ULg; Georges, Marc ULg; Hustinx, Guy-Michel et al

Conference (2008, November)

Les cristaux photoréfractifs permettent l'enregistrement holographique dynamique in-situ et une réutilisabilité infinie. Aussi ils possèdent des propriétés spécifiques que d'autres matériaux ... [more ▼]

Les cristaux photoréfractifs permettent l'enregistrement holographique dynamique in-situ et une réutilisabilité infinie. Aussi ils possèdent des propriétés spécifiques que d'autres matériaux holographiques n'ont pas et qui peuvent être utilisées de manière avantageuse en interférométrie holographique. Depuis 15 ans, le CSL développe des techniques d'interférométrie holographique et des instruments basés sur des cristaux de Bi12SiO20 (BSO). Le comportement dynamique de ces derniers permet une grande souplesse d'utilisation de l'interférométrie holographique, à l'instar des techniques basées sur l'enregistrement numérique, tout en fournissant des interférogrammes de meilleure résolution que celles-ci (pas de bruit de speckle, pas de filtrage nécessaire). Par le passé, nous avons déjà présenté une large gamme d'applications en métrologie, contrôle non destructif et mesures vibratoires. Ici nous présentons des applications industrielles récentes obtenue avec une caméra holographique photoréfractive commercialisée. Cette dernière a été utilisée avec succès dans des applications très demandeuses, notamment en terme de résolution. [less ▲]

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See detailInterférométrie holographique sur base de cristaux photoréfractifs dynamiques et lasers à double impulsion : le projet européen PHIFE
Georges, Marc ULg; Thizy, Cédric ULg; Lemaire, Philippe et al

in Smigielski, P. (Ed.) Actes du Cinquième colloque francophone Méthodes et Techniques Optiques pour l'Industrie (2004, November)

Les cristaux photoréfractifs sont des supports holographiques dynamiques (auto-enregistrables, effaçables et indéfiniment réutilisables) qui permettent l'acquisition rapide d'hologrammes utilisables en ... [more ▼]

Les cristaux photoréfractifs sont des supports holographiques dynamiques (auto-enregistrables, effaçables et indéfiniment réutilisables) qui permettent l'acquisition rapide d'hologrammes utilisables en interférométrie holographique. De plus, certaines de leurs propriétés cristallines permettent l'obtention d'interférogrammes de qualité incomparable. Nous avons déjà présenté à maintes reprises les développements et applications d'instruments de métrologie basés sur ces cristaux avec des lasers continus. Des expériences préliminaires sur base de lasers à simple impulsion avaient aussi été montrées. Nous présentons ici la suite de ces expériences et qui ont lieu dans le cadre du projet européen PHIFE "Pulsed Holographic Interferometer for the analysis of Fast Events". PHIFE a pour objectif le développement d'un instrument à champ complet fonctionnant avec un laser YAG Q-switch à double impulsion. [less ▲]

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See detailInterférométrie RSO et analyses géomorphométriques à caractère tectonique en Jordanie.
Cornet, Yves ULg; De Rauw, Dominique ULg; Ozer, André ULg et al

in Dubois, J. M.; Bernier, M.; Fortin, J. P. (Eds.) et al Série Actualité scientifique - La réalité de terrain en télédétection: pratiques et méthodes (1998)

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See detailInterferon Response Factor 3 is essential for house dust mite-induced airway allergy
Marichal, Thomas ULg; Bedoret, Denis; Mesnil, Claire ULg et al

in Journal of Allergy and Clinical Immunology (The) (2010), 126(4), 836-844

IRF3, mainly known as a central orchestrator of antiviral responses, is required for proallergic functions of dendritic cells in response to aeroallergens. Thus, this study demonstratively identifies a ... [more ▼]

IRF3, mainly known as a central orchestrator of antiviral responses, is required for proallergic functions of dendritic cells in response to aeroallergens. Thus, this study demonstratively identifies a new pathway potentially implicated in the etiology of airway allergy [less ▲]

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See detailInterferon Response Factor 3 is essential for house dust mite-induced airway allergy
Marichal, Thomas ULg; Bedoret, Denis; Mesnil, Claire et al

Conference (2011, May)

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See detailInterferon Response Factor 3 is required for airway allergy to house dust mite in mice
Marichal, Thomas ULg; Bedoret Denis; Mesnil, Claire ULg et al

in Short Book of the Annual Congress of the Euopean Respiratory Society (ERS), Barcelone (2010, September)

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See detailInterferon Response Factor-3 is essential for house dust mite-induced airway allergy
Marichal, Thomas ULg; Bedoret Denis; Mesnil Claire et al

in Proceedings of the Belgian Thoracic Society Annual Meeting (2011, May 23)

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See detailInterferon-induced Sus scrofa Mx1 blocks endocytic traffic of incoming influenza A virus particles
Palm, Mélanie; Garigliany, Mutien-Marie ULg; Cornet, François ULg et al

in Veterinary Research (2010), 41(3), 29

The interferon-induced Mx proteins of vertebrates are dynamin-like GTPases, some isoforms of which can additionally inhibit the life cycle of certain RNA viruses. Here we show that the porcine Mx1 protein ... [more ▼]

The interferon-induced Mx proteins of vertebrates are dynamin-like GTPases, some isoforms of which can additionally inhibit the life cycle of certain RNA viruses. Here we show that the porcine Mx1 protein (poMx1) inhibits replication of influenza A virus and we attempt to identify the step at which the viral life cycle is blocked. In infected cells expressing poMx1, the level of transcripts encoding the viral nucleoprotein is significantly lower than normal, even when secondary transcription is prevented by exposure to cycloheximide. This reveals that a pretranscriptional block participates to the anti-influenza activity. Binding and internalization of incoming virus particles are normal in the presence of poMx1 but centripetal traffic to the late endosomes is interrupted. Surprisingly but decisively, poMx1 significantly alters binding of early endosome autoantigen 1 to early endosomes and/or early endosome size and spatial distribution. This is compatible with impairment of traffic of the endocytic vesicles to the late endosomes. [less ▲]

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See detailLes interférons de type 1 et leur fonction antivirale
Leroy, Michael; Desmecht, Daniel ULg

in Annales de Médecine Vétérinaire (2006), 150(2), 73-107

Type I interferons are part of the innate immune system involved in the first line defense against invasion, replication and spreading of pathogens such as viruses. Through specific membrane or ... [more ▼]

Type I interferons are part of the innate immune system involved in the first line defense against invasion, replication and spreading of pathogens such as viruses. Through specific membrane or intracellular receptors, virus entry induces the expression of type I interferons which stimulates the cells through an autocrine and paracrine manner. Interferons are polypeptides that stimulate cells through membrane receptors. They induce a cascade of events leading to the synthesis of many proteins some of which having specific antiviral properties. The most characterized are the MX proteins, the 2’5’ oligoadenylate synthetase/ ribonuclease L pathway and the double-stranded RNA-dependent protein kinase R system. Recently, the protein ISG20 has been involved in the specific antiviral function of type I interferons. The interferons act on multiple steps of the viral cycle including penetration, decapsidation, mRNA transcription, protein synthesis, genome replication, assembling and excretion of viral particles. Nowadays, due to their major efficiency, type I interferons are used in therapeutics against some viral infections and cancers. [less ▲]

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See detailInterfollicular fibrosis and organohalogens in the thyroid of the harbour porpoise (phocoena phocoena) of the British and Belgian coasts
Schnitzler, Joseph ULg; Das, Krishna ULg; Beineke, Andreas et al

Conference (2005, October 27)

Previous studies have described high levels of polychlorobiphenyls (PCB), p,p`-dichlordiphenyl-dichlorethen (DDT), p,p`-dichlordiphenyl-trichlorethan (DDE) and polybrominated diphenylether (PBDE) in the ... [more ▼]

Previous studies have described high levels of polychlorobiphenyls (PCB), p,p`-dichlordiphenyl-dichlorethen (DDT), p,p`-dichlordiphenyl-trichlorethan (DDE) and polybrominated diphenylether (PBDE) in the blubber of the harbour porpoise (Phocoena phocoena) from the North Sea raising the question of a potential endocrine disruption in this species. In the present study, the thyroids of 36 harbour porpoises from the British and the Belgian coast have been collected for histological and immunohistological investigations. The number and mean diameter of follicles and the relative distribution of follicular, connective and vascular tissues (%) were quantified in the thyroid of each individual. Then, the relationship between the thyroid morphometry data and previously described organic compounds (namely PCB, DDT, DDE and PBDE) was investigated using factor analysis and multiple regressions. The results of this work were compared to the previous study of harbour porpoises from the German (North and Baltic Seas), Norwegian and Icelandic coasts. Thyroid morphology was similar between the harbour porpoises from the British and Belgian coast. Compared to the previous study, the thyroids differed strongly between sampling sites. Porpoises from the German (North and Baltic Seas) and Norwegian coasts displayed a high percentage of connective tissues between 30 and 38% revealing severe inter-follicular fibrosis. The thyroids of Icelandic coasts displayed only a light inter-follicular fibrosis (percentage of connective tissue of 3%). The thyroids of the porpoises from the British and Belgian coasts occupied an intermediary place with a moderate fibrosis (percentage of connective tissue of 10%). A relation between mean diameter of follicles and the body size and mass suggesting a downward trend of activity of the thyroid with increasing body size and mass and thus, the age of the porpoises. A correlation-based principal component analysis (PCA) revealed one principal components explaining 69% of the total variance. The variables PCB, PBDE, DDT, and DDE compounds loaded highest on PC1. Our results pointed out a relationship between PCBs, PBDE, DDE and DDT (PC1) compounds and interfollicular fibrosis in the thyroids of harbour porpoises from the German coast of the Baltic Sea. The present report supports the hypothesis of a contaminant-induced thyroid fibrosis in harbour porpoises raising the question of the long term-viability in highly polluted areas [less ▲]

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See detailInterfollicular fibrosis in the thyroid of the harbour porpoise: An endocrine disruption?
Das, Krishna ULg; Vossen, Arndt; Tolley, Kristal et al

in Archives of Environmental Contamination & Toxicology (2006), 51

Previous studies have described high levels of polychlorobiphenyls (PCB), polybrominated diphenylether (PBDE), toxaphene, ,p0-dichlorodiphenyltrichloroethane (DDT), and ,p0 ... [more ▼]

Previous studies have described high levels of polychlorobiphenyls (PCB), polybrominated diphenylether (PBDE), toxaphene, ,p0-dichlorodiphenyltrichloroethane (DDT), and ,p0-dichlorodiphenyldichloroethylene (DDE) in the blubber of the harbour porpoise from the North Sea raising the question of a potential endocrine disruption in this species. In the present study, the thyroids of 57 harbour porpoises from the German and Danish (North and Baltic Seas), Norwegian, and Icelandic coasts have been collected for histological and immunohistological investigations. The number of follicles and the relative distribution of follicles, connective, and solid tissues (%) were quantified in the thyroid of each individual. Then, the potential relationship between the thyroid morphometry data and previously described organic compounds (namely, PCB, PBDE, toxaphene, DDT, and DDE) was investigated using factor analysis and multiple regressions. Thyroid morphology differed strongly between ampling sites. Porpoises from the German (North and Baltic Seas) and Norwegian coasts displayed a high percentage of connective tissues between 30 and 38% revealing severe interfollicular fibrosis and a high number of large follicles (diameter >200 lm). A correlation-based principal component analysis (PCA) revealed two principal components explaining 85.9% of the total variance. The variables PCB, PBDE, DDT, and DDE compounds loaded highest on PC1 whereas toxaphene compound loaded most on PC2. Our results pointed out a relationship between PC1 (PCBs, PBDE, DDE, and DDT compounds) and interfollicular fibrosis in the harbour porpoise thyroids. Such an association is not alone sufficient for a cause–effect relationship but supports the hypothesis of a contaminant-induced thyroid fibrosis in harbour porpoises raising the question of the longterm viability in highly polluted areas. [less ▲]

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See detailIntergenerational conflict in the first trilogy of Nuruddin Farah
Bajou, Issam ULg

Conference (2014, April)

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See detailThe interglacial carbon cycle
Kleinen, Thomas; Brovkin, Victor; Munhoven, Guy ULg et al

Poster (2011, April 07)

Explaining the difference in carbon cycle dynamics (and hence atmospheric CO2) between various interglacials is an elusive issue. Several biogeochemical mechanisms of different origin are involved in ... [more ▼]

Explaining the difference in carbon cycle dynamics (and hence atmospheric CO2) between various interglacials is an elusive issue. Several biogeochemical mechanisms of different origin are involved in interglacial CO2 dynamics, leading to a CO2 release from the ocean (carbonate compensation, coral growth) compensated by a land carbon uptake (biomass and soil carbon buildup, peat accumulation). The balance between these fluxes of CO2 is delicate and time-dependent, and it is not possible to provide firm constraints on these fluxes from proxy data. The best framework for quantification of all these mechanisms is an Earth System model that includes all necessary physical and biogeochemical components of the atmosphere, ocean, and land. To perform multi-millennial model integrations through the Holocene, Eemian, and MIS11, we use an earth system model of intermediate complexity, CLIMBER-2, coupled to the dynamic global vegetation model LPJ with a recently implemented module for boreal peatland dynamics. During glacial-interglacial cycles, the carbon cycle never is in complete equilibrium due to a number of small but persistent fluxes such as terrestrial weathering. This complicates setting up interglacial experiments as the usual approach to start model integrations from an equilibrium state is not valid any more. In order to circumvent the problem of non-equilibrium initial conditions, the model is initialised with the oceanic biogeochemistry state taken from a transient simulation through the last glacial cycle with CLIMBER-2 only. In this simulation, the CLIMBER-2 model was run through the last glacial cycle with carbon cycle in “offline mode” as interactive components of the physical climate system (atmosphere, ocean, ice sheets) were driven by concentration of greenhouse gases reconstructed from ice cores. Using these initial conditions, we performed coupled climate carbon cycle experiments for the Holocene, the Eemian and MIS11, driven by orbital forcing. Contrary to the results we published previously (Kleinen et al. 2010), peat accumulation was not prescribed, but rather determined dynamically, making this model setup applicable to previous interglacials as well. For the Holocene, our results resemble the carbon cycle dynamics as reconstructed from ice cores quite closely, both for atmospheric CO2 and delta13CO2. These experiments will be presented, analysing the role of different forcing mechanisms. The land surface appears to be an overall sink for CO2, due to carbon accumulation in the soil, as well as peat accumulation, and oceanic contributions due to temperature and circulation changes are quite small. Finally, results for MIS11 and the Eemian will be shown. [less ▲]

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