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See detailImpact of participatory risk assessment approaches on occupational health professional's attitutdes and practices Proceedings ICOH 2009
Mairiaux, Philippe ULg; Mazina, D. ULg; Roussel, Sandrine et al

Poster (2009, March)

In the last 10 years with the support of the Belgian Federal Public Service (FPS) for Employment and Labour and the European Social Fund, prevention advisors (PA) and occupational health physicians (OP ... [more ▼]

In the last 10 years with the support of the Belgian Federal Public Service (FPS) for Employment and Labour and the European Social Fund, prevention advisors (PA) and occupational health physicians (OP) have been invited to use new methods for risk assessment involving workers’ participation, namely the Sobane strategy, or the Risk/Toxtrainer methodology. This study aimed at evaluating these methods actual use among PA’s and OP’s, and its impact on representations and risk management practices. Methods A national postal survey was conducted in 2007 among a random sample (n=3340) of all professionals registered as PA (>6000) or OP (about 1000) by the FPS. The questionnaire explored those professionals’ familiarity with 12 different risk assessments methods, the nature of their interventions in enterprises, their representations about participation and collected demographic information. Results A total of 859 completed surveys (response rate: 25.7 %) could be analyzed. Among the methods studied, the Kinney-Wiruth accident risk analysis is the most familiar (54% regular users + 19% trained ones). The participatory methods are familiar (users + trained) to respectively 46 % (Sobane) and 11% (Risktrainer) of the respondents. When analyzing practices in enterprises, the professionals familiar with one of the participatory approaches are more often than the other professionals suggesting the use of participation in risk management to colleagues (84 vs 67.5% ; p<0.000) or to the employer (84 vs 73.5% ; p<0.000). Those professionals not familiar with the participatory approaches agree more often with the following statements: “PA role is more to inform than to listen” (p=0.005), “Participatory processes are raising unrealistic expectations among the staff” (p=0.002). Discussion This study shows that participatory risk assessment methods are gaining ground in Belgian enterprises. It also highlights the significant influence that information and training in those methods have had on risk management practices and the professionals’ representations. [less ▲]

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Peer Reviewed
See detailImpact of participatory risk assessment approaches on occupational health professional's attitudes and practices
Mairiaux, Philippe ULg; Mazina, D. ULg; Roussel, Sandrine et al

Poster (2009, March)

Introduction In the last 10 years with the support of the Belgian Federal Public Service (FPS) for Employment and Labour and the European Social Fund, prevention advisors (PA) and occupational health ... [more ▼]

Introduction In the last 10 years with the support of the Belgian Federal Public Service (FPS) for Employment and Labour and the European Social Fund, prevention advisors (PA) and occupational health physicians (OP) have been invited to use new methods for risk assessment involving workers’ participation, namely the Sobane strategy, or the Risk/Toxtrainer methodology. This study aimed at evaluating these methods actual use among PA’s and OP’s, and its impact on representations and risk management practices. Methods A national postal survey was conducted in 2007 among a random sample (n=3340) of all professionals registered as PA (>6000) or OP (about 1000) by the FPS. The questionnaire explored those professionals’ familiarity with 12 different risk assessments methods, the nature of their interventions in enterprises, their representations about participation and collected demographic information. Results A total of 859 completed surveys (response rate: 25.7 %) could be analyzed. Among the methods studied, the Kinney-Wiruth accident risk analysis is the most familiar (54% regular users + 19% trained ones). The participatory methods are familiar (users + trained) to respectively 46 % (Sobane) and 11% (Risktrainer) of the respondents. When analyzing practices in enterprises, the professionals familiar with one of the participatory approaches are more often than the other professionals suggesting the use of participation in risk management to colleagues (84 vs 67.5% ; p<0.000) or to the employer (84 vs 73.5% ; p<0.000). Those professionals not familiar with the participatory approaches agree more often with the following statements: “PA role is more to inform than to listen” (p=0.005), “Participatory processes are raising unrealistic expectations among the staff” (p=0.002). Discussion This study shows that participatory risk assessment methods are gaining ground in Belgian enterprises. It also highlights the significant influence that information and training in those methods have had on risk management practices and the professionals’ representations. [less ▲]

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See detailImpact of Percutaneous Oestradiol Gels in Postmenopausal Hormone Replacement Therapy on Clinical Symptoms and Endometrium
Foidart, Jean-Michel ULg; Beliard, Aude ULg; Hedon, B. et al

in British Journal of Obstetrics & Gynaecology (1997), 104(3), 305-10

OBJECTIVE: To compare the effects on endometrium, climacteric symptoms and the menstrual cycle, and the clinical and biological tolerance of two percutaneous oestradiol gels used as hormone replacement ... [more ▼]

OBJECTIVE: To compare the effects on endometrium, climacteric symptoms and the menstrual cycle, and the clinical and biological tolerance of two percutaneous oestradiol gels used as hormone replacement therapy. DESIGN: A large open randomised multicentre study. SETTING: France and Belgium. PARTICIPANTS: Two-hundred and fifty-four women with an intact uterus and who had experienced a natural menopause received either Oestrogel (n = 126) or Estreva, a new formulation of oestradiol gel (n = 128), (1.5 mg of oestradiol/day) for the 24 first days of each calendar month during six consecutive months. Nomegestrol acetate (Lutenyl), a norprogesterone derivative, was administered (5 mg/day) from day 11 to day 24 of each oestradiol cycle. MAIN OUTCOME MEASURES: Examination of endometrial biopsies taken before treatment and between days 18 and 24 of the last treatment cycle, climacteric symptoms assessed using a modified Kupperman index, control of menstrual cycle evaluated by diary cards, and clinical and biological tolerance. RESULTS: Both treatments lowered the frequency and intensity of hot flushes and the global Kupperman index. 96% of the cycles were followed by withdrawal bleeding. Breakthrough bleeding or spotting resulted in premature discontinuation of treatment in one volunteer. Mastodynia occurred in 20 women and contributed to the premature termination of treatment in three of them. Endometrial biopsies taken at the end of treatment showed identical histologies in both groups, with a secretory pattern in the majority of women, and absence of hyperplasia. CONCLUSIONS: This trial confirmed that, when the two oestradiol gels tested were administered cyclically with nomegestrol acetate to postmenopausal women, they were well tolerated, effective and suitable for the treatment of oestrogen deficiency syndrome. [less ▲]

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See detailImpact of performance anxiety on the accuracy of the singing voice among music students
Larrouy, Pauline ULg; Clijsters, Céline; Morsomme, Dominique ULg

Poster (2012, May 31)

Performance anxiety causes physical and cognitive symptoms. This emotional state can affect the vocal features thus the fundamental frequency which is the main parameter to evaluate the singing voice ... [more ▼]

Performance anxiety causes physical and cognitive symptoms. This emotional state can affect the vocal features thus the fundamental frequency which is the main parameter to evaluate the singing voice accuracy. The aim of this study is to observe the impact of performance anxiety on the singing voice accuracy. 31 music students from the Royal Conservatories of Belgium sang a melody three times. Twice in quiet situations and one time in a stress situation (the day of the examination). This performance was rated by a panel of teachers. The anxiety level was controlled by measuring the heart frequency. We analyzed errors concerning the interval accuracy and the respect of the tonal center. We observe that the heart frequency is significantly higher in the stress situation (F(2,28)=15,18 ; p<.001), especially for advanced students. The students have difficulty to maintain the tonal center (F(2,12)=7,17 ; p=.03), whereas the accuracy of the intervals is not altered (F(2,12)=1,1 ; p=.56). The rating of the jury correlates with interval accuracy (r=-.411; p=.03) and respect of the tonal center (r=-.452; p=.016), particularly at the beginning of the melody (r=-.516; p=.005). To conclude, performance anxiety leads to an increase of the heart frequency and alters the respect of the tonal center. This is particularly the case for advanced students for whom this situation is a real challenge. [less ▲]

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See detailImpact of Pharyngo laryngeal Reflux on voice quality by using the RFS and RSI on 96 subjects.
Morsomme, Dominique ULg; Sugameli, Mélanie; Verduyckt, Ingrid

Conference (2010, June 05)

Pharyngo Laryngeal Reflux (PLR) influences the voice quality : hoarseness, vocal fatigue and hypertonia (Shaw et al, Hopkins et al). Our goal is to measure the influence of the PLR on the voice of 96 ... [more ▼]

Pharyngo Laryngeal Reflux (PLR) influences the voice quality : hoarseness, vocal fatigue and hypertonia (Shaw et al, Hopkins et al). Our goal is to measure the influence of the PLR on the voice of 96 subjects by using the Belafsky’s reflux symptom index (RSI) and reflux finding score (RFS). 46 dysphonic patients (26M/24F) constitute the experimental group (EG) and 50 subjects (13 M/33F) without vocal or gastric complaint the control group (CG). All are evaluated by subjective measures (RSI), D-type scale (DS-16, Denollet et al) and objective measures (Video Laryngo Stroboscopy, RFS). The EG shows a RSI score significantly higher on test than on the retest (p=0.002). The specificity of the RSI calculated on the CG amounts to 98 % (chi ²: p < 0,05, Cramer: 0,678). The EG scores are significantly higher than those of the CG (p=0,000) although the CG obtains scores significantly higher as for the eating risk habits (p=0,001). In the EG, we note a correlation between the coffee consumption, the item 9 (pyrosis) (rho: 0,32; p < 0,05 ) and the global RSI score (rho: 0,35; p < 0,05). In the CG, alcohol consumption influences significantly the item 9 (rho: 0,47). The correlations between RSI and RFS are not significant (p < 0.05). The ENT evaluation is severe and probably influences the result. We observe no influence of the gender and of the D-type scale on the RSI scores (p <0.05). The RSI scale is an interesting tool for the detection of RPL. [less ▲]

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See detailImpact of phenotypic heterogeneity and metabolic specialisation on metabolic engineering strategies: case of study of E.coli as a representative microbial cell factory
Brognaux, Alison ULg; Delepierre, Anissa ULg; Pecheux, Hélène ULg et al

Conference (2015, July 21)

The goal of this research is to directly highlight the simultaneous occurrence of several phenotypes with distinct metabolic function among clonal population of E. coli., often used for recombinant ... [more ▼]

The goal of this research is to directly highlight the simultaneous occurrence of several phenotypes with distinct metabolic function among clonal population of E. coli., often used for recombinant protein and pDNA production in bioprocesses. This phenotypic heterogeneity, first due to the noise, is reinforced by environmental heterogeneities occurring at large scale during fed-batch processes. This phenotypic heterogeneity has been tracked according to GFP reporter strains (biosensors) that circulate in the bioreactor and encounter environmental heterogeneities. First, we have highlighted the simultaneous occurrence of several phenotypes with distinct metabolic functions. Indeed, a diversity of glucose uptake strategies has recently been noticed with the PtsG and MglABC transporters. Moreover, when E.coli encounters zones of glucose excess, acetate is produced through the overflow metabolism. Only the sub-population with high acs expression (acetate transporter) could consume this acetate. GFP reporter strains have thus been constructed for PtsG, MgIABC and acs genes. In addition of the stable GFP, two destabilized GFP variants for each gene have been used to obtain more instantaneous responses. The response of these biosensors have been followed by on-line flow cytometry. In the end, this experimental strategy for direct phenotyping at the single cell level will also be used to investigate the impact of metabolic engineering strategies on phenotypic heterogeneity, robustness and fitness of microbial population in industrial conditions. [less ▲]

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See detailImpact of phonological awareness on reading and writing in Down’s syndrome
Frenkel, Stéphanie ULg; Vicari, Stefano

Conference (2010, June)

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See detailImpact of physical properties of inulin on stability during moisture sorption.
Ronkart, Sébastien; Paquot, Michel ULg; Fougnies, C. et al

Poster (2008, July)

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See detailImpact of place of residence on relationship between quality of life and cognitive decline in dementia
Missotten, Pierre ULg; Thomas, Philippe; Squelard, Gilles ULg et al

in Alzheimer Disease and Associated Disorders (2009), 23(4), 395-400

The aim of this descriptive study was to estimate and compare the association between cognitive decline and quality of life (QOL) for 2 groups of dementia patients differing by place of residence: home or ... [more ▼]

The aim of this descriptive study was to estimate and compare the association between cognitive decline and quality of life (QOL) for 2 groups of dementia patients differing by place of residence: home or institution. Each subject was placed within a specific subgroup according to their Mini-Mental State Examination (MMSE) score and was evaluated by a QOL proxy-assessment [Alzheimer Disease Related Quality of Life (ADRQL)] and a dependency assessment (Katz Activities of Daily Living classification). For the ‘‘at home’’ and ‘‘institution’’ groups, global and subscale ADRQL scores showed significant differences between the 5 MMSE subgroups. Place of residence and MMSE subgroups significantly affected global and subscale ADRQL scores. The MMSE 4 to 8, 9 to 13, and 14 to 18 subgroups had ADRQL global scores significantly better in the institution group than the at home group. In contrast, the MMSE 19 to 23 and 0 to 3 subgroups had similar ADRQL global scores in both places of residence. In conclusion, there is no direct relationship between cognitive decline and QOL, and QOL does not seem to be better at home compared with the institution. [less ▲]

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See detailImpact of polyunsaturated fatty acid degradation on survival and acidification activity of freeze-dried Weissella paramesenteroides LC11 during storage
Yao, Amenan Anastasie ULg; Coulibaly, Ibourahema ULg; Lognay, Georges ULg et al

in Applied Microbiology & Biotechnology (2008), 79(6), 1045-1052

Abstract The impact of polyunsaturated fatty acid (PUFA) degradation on the survival and acidification activity of freeze-dried Weissella paramesenteroides LC11 was investigated over 90-days storage at 4 ... [more ▼]

Abstract The impact of polyunsaturated fatty acid (PUFA) degradation on the survival and acidification activity of freeze-dried Weissella paramesenteroides LC11 was investigated over 90-days storage at 4 °C or 20 °C in vacuumsealed aluminium foil or glass tubes with two water activities (aw=0.11 or 0.23). Colony counts, acidification activity (% lactic acid/g), linoleic/palmitic (18:2/16:0) or linolenic/palmitic (18:3/16:0) ratio by gas chromatography and 18:2 or 18:3 oxylipins by reversed phase-high performance liquid chromatography were determined. The viable cells, acidification activity and 18:2/16:0 or 18:3/ 16:0 ratio decreased as the storage time increased. The survival, acidification activity and 18:2/16:0 or 18:3/16:0 ratio were greatest for the freeze-dried strain held in vacuum-sealed aluminium foil at 4 °C. The 18:2/16:0 or 18:3/16:0 ratio decrease was correlated with the accumulation of 18:2 or 18:3 oxylipins during storage in glass tubes. Hydroperoxy PUFAs, hydroxy PUFAs, divinyl ether PUFAs and oxo PUFAs were the main oxylipins identified. A large decrease in the 18:2/16:0 or 18:3/16:0 ratio and a rapid accumulation of oxylipins during storage might be enough to cause high cell death and loss of metabolic activity. These results provide further experimental support for the hypothesis that lipid oxidation and survival or activity of freeze-dried bacteria might be related. [less ▲]

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See detailImpact of poor adherence to bisphosphonates therapy on hip fracture risk in osteoporotic women
Rabenda, Véronique ULg; Fabri, Véronique; Mertens, Raf et al

in Arthritis and Rheumatism (2007, September), 56(number 9 (suppl.)), 271

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See detailImpact of population history on Viola calaminaria conservation, an endemic species of calamine sites
Bizoux, Jean-Philippe ULg; Mahy, Grégory ULg

Conference (2011, June)

The zinc violet, Viola calaminaria is a threatened species, endemic to calamine sites in Belgium and West Germany. Since the end of 19th century, the V. calaminaria habitat network have exhibited a huge ... [more ▼]

The zinc violet, Viola calaminaria is a threatened species, endemic to calamine sites in Belgium and West Germany. Since the end of 19th century, the V. calaminaria habitat network have exhibited a huge dynamics, with creation of new habitats resulting from industrial pollution and destruction of habitats by urbanisation and site remediation. In the present study, we analysed the effect of population history (recent/ancient population) on genetic diversity, fitness and reproductive success in order to discuss conservation strategies for the species. Recently founded populations exhibited similar level of genetic diversity (Hs) as ancient populations but showed a lower genetic differentiation among population (Fst). No indication of strong founder effects in recently established populations was detected. Plant fitness (seed set and germination percentage) was higher in recent populations while other reproductive traits (vegetative density, flower density, fructification percentage) did not differ according to population history. Results suggest that the creation of habitats through human activities can provide new opportunities for conservation of this species. In increasingly disturbed environments, this indicates that, at least for some species, conservation strategies should not focus solely on traditional and natural habitats but also consider the potential benefits offered by modified landscapes. [less ▲]

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See detailImpact of pre-treatment processing on cereal by-products valorisation through enzymatic extraction of ferulic acid.
Barberousse, Hélène; Roiseux, Olivier; Deroanne, Claude et al

Poster (2008, June)

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See detailImpact of pro-oxidant agents on the morula-blastocyst transition in bovine embryos.
Feugang, Jean-Magloire; Donnay, Isabelle; Mermillod, Pascal et al

in Molecular Reproduction and Development (2005), 71(3), 339-46

Exposing day 5 bovine morulae to reactive oxygen species induces a delayed degeneration of some blastocysts on day 8 post-insemination (pi) but without affecting the blastocyst rates. The aim of this ... [more ▼]

Exposing day 5 bovine morulae to reactive oxygen species induces a delayed degeneration of some blastocysts on day 8 post-insemination (pi) but without affecting the blastocyst rates. The aim of this study was to characterize the resisting and the degenerating population of blastocysts. The kinetics of degeneration of the embryos exposed to the two pro-oxidant agents: 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH) and buthionine sulfoximine (BSO) was evaluated using time-lapse cinematography. With both agents the first signs of degeneration appeared at day 7.5 pi but the duration of the degeneration process was shorter in presence of AAPH than BSO (4.2 vs. 12.5 hr, ANOVA, P < 0.05). The resisting blastocysts derived from morulae with a larger diameter (mean diameter: 161 vs. 154 microm, ANOVA, P < 0.05) and showed an earlier cavitation (135 vs. 142 hpi, P < 0.05) than the degenerating ones. The profile of protein neosynthesis at day 7 was not affected by the treatment. The proportion of male embryos was more important in the resisting than in the degenerating population (70 vs. 55%, chi2, P < 0.05) especially when the stress was induced by AAPH. The quality of the resisting embryos, measured by the total cell number and the rate of apoptosis, did not seem to be affected when compared to control embryos. In conclusion, resistance to oxidative stress seems related to the kinetics of development and/or the sex of the embryos. Resisting embryos apparently display a quality similar to untreated embryos. [less ▲]

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See detailImpact of prosthesis-patient mismatch on mitral regurgitation after aortic valve replacement
Unger, P.; Magne, Julien ULg; Vanden Eynden, F. et al

in Heart (2010), 96(20), 1627-1632

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See detailImpact of prosthesis-patient mismatch on short-term mortality following mitral valve replacement.
Magne, Julien ULg; Mathieu, P; Dumesnil, JG et al

Conference (2008)

Detailed reference viewed: 5 (0 ULg)