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See detailInvolvement of phenolic compounds in the susceptibility of bananas to crown rot. A review.
Ewane, Cécile Annie; Lepoivre, Philippe ULg; de Lapeyre de Bellaire, Luc et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2012), 16(3), 393-404

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See detailInvolvement of Placental growth factor in Wallerian degeneration
Chaballe, Linda ULg; Close, Pierre ULg; Sempels, Maxime ULg et al

Poster (2010, September)

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See detailInvolvement of placental growth factor in Wallerian degeneration
Chaballe, Linda ULg; Close, Pierre ULg; SEMPELS, Maxime ULg et al

in Glia (2011), 59(3), 379-396

Wallerian degeneration (WD) is an inflammatory process of nerve degeneration, which occurs more rapidly in the peripheral nervous system compared with the central nervous system, resulting, respectively ... [more ▼]

Wallerian degeneration (WD) is an inflammatory process of nerve degeneration, which occurs more rapidly in the peripheral nervous system compared with the central nervous system, resulting, respectively in successful and aborted axon regeneration. In the peripheral nervous system, Schwann cells (SCs) and macrophages, under the control of a network of cytokines and chemokines, represent the main cell types involved in this process. Within this network, the role of placental growth factor (PlGF) remains totally unknown. However, properties like monocyte activation/attraction, ability to increase expression of pro-inflammatory molecules, as well as neuroprotective effects, make it a candidate likely implicated in this process. Also, nothing is described about the expression and localization of this molecule in the peripheral nervous system. To address these original questions, we decided to study PlGF expression under physiological and degenerative conditions and to explore its role in WD, using a model of sciatic nerve transection in wild-type and Pgf(-/-) mice. Our data show dynamic changes of PlGF expression, from periaxonal in normal nerve to SCs 24h postinjury, in parallel with a p65/NF-κB recruitment on Pgf promoter. After injury, SC proliferation is reduced by 30% in absence of PlGF. Macrophage invasion is significantly delayed in Pgf(-/-) mice compared with wild-type mice, which results in worse functional recovery. MCP-1 and proMMP-9 exhibit a 3-fold reduction of their relative expressions in Pgf(-/-) injured nerves, as demonstrated by cytokine array. In conclusion, this work originally describes PlGF as a novel member of the cytokine network of WD. [less ▲]

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See detailInvolvement of polyamines in the adventitious rooting of micropropagated shoots of the apple rootstock MM106
Naija, Sélima; Elloumi, Nadhra; Ammar, Saida et al

in In Vitro Cellular & Developmental Biology-Plant (2009), 45

Apple rootstock MM106 shoots, raised in vitro, rooted at 96.7% after culture on a medium supplemented with an auxin for 5 d in darkness followed by culture on a second medium without growth regulators for ... [more ▼]

Apple rootstock MM106 shoots, raised in vitro, rooted at 96.7% after culture on a medium supplemented with an auxin for 5 d in darkness followed by culture on a second medium without growth regulators for 25 d in light. In control conditions (in absence of auxin in the first medium), these shoots did not root. Putrescine (PUT), spermidine (SPD), cyclohexylamine (CHA), and aminoguanidine (AG) enhanced rooting when applied during the first d of culture in the absence of IBA; on the contrary, α-difluoromethylornithine (DFMO) added to the first medium with IBA inhibited rooting. The endogenous levels of indole 3-acetic acid (IAA) and indole 3-acetylaspartic acid (IAAsp) increased up to a maximum concentration at days 2 and 3, respectively, in initial rooting conditions. PUT, when added with IBA, did not affect the typical IAA and IAAsp increase; when applied alone, it provoked an increase of their levels. Similar results were recorded with CHA. SPD, AG, and DFMO did not induce an increase of IAA and IAAsp in nonrooting conditions. The levels of endogenous PUT increased to a maximum at day 2 in rooting conditions; it was slightly affected by exogenous PUT and CHA application but reduced by SPD, AG, and DFMO. In rooting conditions, if the first medium was supplemented with SPD or AG, a small increase in peroxidase activity was observed, similar to that obtained with PUT treatment. The present work indicates an involvement of polyamines in the control of rooting and an interaction with auxins during the physiological phase of rooting. The consequence of this relationship was a different rooting expression, according especially to the content of these regulators in the culture medium. [less ▲]

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See detailInvolvement of the brain histaminergic system in addiction and addiction-related behaviors: a comprehensive review with emphasis on the potential therapeutic use of histaminergic compounds in drug dependence
Brabant, Christian ULg; Alleva, Livia ULg; Quertemont, Etienne ULg et al

in Progress in Neurobiology (2010), 92

Neurons that produce histamine are exclusively located in the tuberomamillary nucleus of the posterior hypothalamus and send widespread projections to almost all brain areas. Neuronal histamine is ... [more ▼]

Neurons that produce histamine are exclusively located in the tuberomamillary nucleus of the posterior hypothalamus and send widespread projections to almost all brain areas. Neuronal histamine is involved in many physiological and behavioral functions such as arousal, feeding behavior and learning. Although conflicting data have been published, several studies have also demonstrated a role of histamine in the psychomotor and rewarding effects of addictive drugs. Pharmacological and brain lesion experiments initially led to the proposition that the histaminergic system exerts an inhibitory influence on drug reward processes, opposed to that of the dopaminergic system. The purpose of this review is to summarize the relevant literature on this topic and to discuss whether the inhibitory function of histamine on drug reward is supported by current evidence from published results. Research conducted during the past decade demonstrated that the ability of many antihistaminic drugs to potentiate addictionrelated behaviors essentially results from non-specific effects and does not constitute a valid argument in support of an inhibitory function of histamine on reward processes. The reviewed findings also indicate that histamine can either stimulate or inhibit the dopamine mesolimbic system through distinct neuronal mechanisms involving different histamine receptors. Finally, the hypothesis that the histaminergic system plays an inhibitory role on drug reward appears to be essentially supported by place conditioning studies that focused on morphine reward. The present review suggests that the development of drugs capable of activating the histaminergic system may offer promising therapeutic tools for the treatment of opioid dependence. [less ▲]

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See detailInvolvement of the community in physical activity promotion. Analysis of the Wallonian context
Cloes, Marc ULg

Conference (2011, November)

Communities are in the center of the action aiming to promote physical activity. Their links with the schools are a determining factor for the global policy. This presentation is focused on the current ... [more ▼]

Communities are in the center of the action aiming to promote physical activity. Their links with the schools are a determining factor for the global policy. This presentation is focused on the current situation of this necessary collaboration in a European region: Wallonia (French speaking part of Belgium). Several studies conducted since the beginning of the 21st century are analyzed in order to point out the real relationships between the schools and the communities. Between the theory based on the official policies and the concrete actions implemented on the field, it seems that the vision is less enthusiastic than expected. [less ▲]

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See detailInvolvement Of The Cyclic Amp-Responsive Element-Binding Protein In Bovine Leukemia-Virus Expression In-Vivo
Adam, E.; Kerkhofs, P.; Mammerickx, M. et al

in Journal of Virology (1994), 68(9),

Detailed reference viewed: 7 (1 ULg)
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See detailInvolvement of the GABA-A sites in the inhibitive effects of nicotine on individual behaviors in mice
Mancuso, G.; Tirelli, Ezio ULg

in Pflügers Archiv : European Journal of Physiology (1995), 333

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See detailInvolvement of the lipoxygenase pathway in the systemic resistance induced by Plant Growth-Promoting Rhizobacteria in tomato
Mariutto, Martin ULg

Doctoral thesis (2013)

The treatment of plant roots with some Plant Growth Promoting Rhizobacteria (PGPR) results in the enhancement of the immune capacity of the host against phytopathogens. This phenomenon called Induced ... [more ▼]

The treatment of plant roots with some Plant Growth Promoting Rhizobacteria (PGPR) results in the enhancement of the immune capacity of the host against phytopathogens. This phenomenon called Induced Systemic Resistance (ISR) is observed in the whole plant and is effective against a broad spectrum of diseases. Many previous studies showed that this resistance is associated, in some pathosystems, with the stimulation of the key enzyme of the lipoxygenase (LOX) pathway. This defense pathway synthesizes antibiotic and signal compounds called oxylipins from poly unsaturated fatty acids. The main goal of our work was to analyse the involvement of the LOX pathway during the ISR in tomato plants The different steps of the pathway were analyzed at the transcriptional, enzymatic and metabolic levels in leaves of tomato plants elicited with the PGPR Pseudomonas putida BTP1, before and after infection by the fungal pathogen Botrytis cinerea. Our study showed that the bacterial treatment reprogrammed the LOX pathway. Before infection, the activity of the key enzyme of the pathway, the LOX, was higher in P. putida BTP1-treated plants compared to control plants. This stimulation resulted in the accumulation 13-hydroperoxy fatty acids and 13-hydroxyfatty acids conjugated to phospholipids and galactolipids. These products could constitute a pool of antifungal compounds that can be used during the pathogen attack. During the first days after B. cinerea inoculation, the LOX activity, the accumulation of one of its substrate (linolenic acid) and of its products were stimulated in treated plants as compared to control plants. The increase of LOX activity was caused by the induction of the expression level of two Lox genes: TomLoxD and TomLoxF. We observed a decrease of the pool of conjugated oxylipins and a concomitant increase of non conjugated oxylipins, associated with the stimulation of the phospholipase A2 activity. The branches of the pathway which can use the products of the LOX as substrate were differentially regulated resulting in the accumulation of fungitoxic oxylipins against B. cinerea. In order to determine if the induction of the LOX pathway is a general feature of the ISR in tomato, the effect of other PGPR and resistance elicitors produced by PGPR was analysed. Three pure bacterial elicitors sharing common biosurfactant features (the n-alkylated benzylamine derivative (NABD) produced by P. putida BTP1, the surfactin synthesized by many Bacillus strains and rhamnolipids purified from P. aeruginosa) and six Bacillus strains including strong, medium and non producers of surfactin were applied onto tomato roots. The analysis of the key points of the modulation of the LOX pathway showed that the plant molecular response depended on the studied organ (root / leaf), the nature of the elicitor and the amount of elicitor produced by the PGPR. In addition to our study on the involvement of the LOX pathway, we searched other mechanisms potentially induced in ISR-expressing plants. The combination of histological staining, quantification of enzymatic activities and analysis of the genome expression by hybridization on DNA gene chips showed additional defense genes and pathways involved in the resistance in tomato. In conclusion, our work showed that the LOX pathway is one of the defense mechanisms which can be involved in ISR in tomato. The elicitation of the resistance allows the plant to prepare to a future infection, and to respond faster and in a more effective way to a subsequent pathogen invasion. [less ▲]

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See detailInvolvement of the secreted serine protease Sub3 of Microsporum canis in adherence to feline epidermis
Mathy, Anne ULg; Tabart, J.; Vermout, S. et al

Conference (2009)

Detailed reference viewed: 28 (9 ULg)
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See detailInvolvement of thyroid hormones in the regulation of mitochondrial oxidations in mammals and birds
Collin, A.; Joubert, R.; Swennen, Q. et al

in Thyroid Hormones: Functions, Related Diseases and Uses (2009)

Detailed reference viewed: 7 (0 ULg)
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See detailInvolvement of z-MMP-2 in Zebrafish lymphangiogenesis
Paupert, Jenny ULg; Pendeville, Hélène; Detry, Benoît ULg et al

Poster (2011, May)

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See detailInvolvement of z-MMP-2 in Zebrafish lymphangiogenesis
Paupert, Jenny ULg; Pendeville, Hélène; Detry, Benoît ULg et al

Conference (2011)

Detailed reference viewed: 16 (2 ULg)
See detailInvolving Students in planning the learning process
Schillings, Patricia ULg

in Garbe, C.; Holle, K.; Weinhold, S. (Eds.) Adore-Teaching struggling adolescent readers in European Countries. Key elements of good practices (2010)

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See detailInvolving Students in texts
Schillings, Patricia ULg; Gabelica, C.

in Garbe, C.; Holle, K.; Weinhold, S. (Eds.) Adore-Teaching struggling adolescent readers in European Countries. Key elements of good practices (2010)

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See detailInżyneria powierzchni betonu. Część 1. Struktura geometryczna powierzchni.
Garbacz, Andrzej; Piotrowski, Tomasz; Courard, Luc ULg

in Materialy Budowlane (2006), 9

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See detailInżyneria powierzchni betonu. Część 1. Struktura geometryczna powierzchni.
Garbacz, Andrzej; Piotrowski, Tomasz; Courard, Luc ULg

in Materialy Budowlane (2006), 9

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See detailInżyneria powierzchni betonu. Część 2. Wpływ obrobki na powstawanie rys
Courard, Luc ULg; Garbacz, Andrzej; Nieweglowska, Anna et al

in Materialy Budowlane (2006), 12

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See detailInżynieria powierzchni betonu. Część 3. Termodynamiczne uwarunkowania adhezji
Courard, Luc ULg; Garbacz, Andrzej; Piotrowski, Tomasz

in Materialy Budowlane (2007), 2

Detailed reference viewed: 24 (1 ULg)