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See detailIntérêt d'une procédure de rappel indicé à 48 items dans le diagnostic précoce de la maladie d'Alzheimer
Ivanoiu, Adrian; Adam, Stéphane ULg; Béchet, Sophie et al

in Revue Neurologique (1999), 155

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See detailIntérêt d’une seconde infiltration de plasma riche en plaquettes dans le traitement des tendinopathies patellaires ?
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Buhler, Frédéric et al

in 7ème Congrès National SFMES & SFTS 2014 (2014, September)

Introduction : Des études cliniques ont évalué l’effet du plasma riche en plaquettes (PRP) dans le traitement de la tendinopathie patellaire. Même si une seule infiltration peut améliorer les symptômes du ... [more ▼]

Introduction : Des études cliniques ont évalué l’effet du plasma riche en plaquettes (PRP) dans le traitement de la tendinopathie patellaire. Même si une seule infiltration peut améliorer les symptômes du sportif dans cette indication, la majorité des études évaluent les effets de 3 infiltrations successives. Le but de notre étude était donc de comparer l’efficacité d’une et de 2 infiltrations (rapprochées) de PRP dans le cade de tendinopathies patellaires chroniques, rebelles aux traitements conservateurs. Matériel et méthode : Vingt sportifs souffrant de tendinopathie patellaire depuis plus de 3 mois ont été inclus et randomisés en 2 groupes, respectivement 1 ou 2 infiltrations de PRP (15 jours d’intervalle). Le PRP a été obtenu à l’aide d’une machine d’aphérèse permettant d’obtenir une concentration plaquettaire identique pour tous les sujets. Ils ont bénéficié ensuite d’une rééducation excentrique sous-maximale standardisée. Le suivi a été réalisé à l’aide d’une échelle visuelle analogique de la douleur, de scores algo-fonctionnels (IKDC et VISA-P), ainsi qu’un questionnaire « mode de vie » avant l’infiltration, 3 et 12 mois post-infiltration. Résultats: La concentration de PRP employée était la même au sein des 2 groupes (9x106/µL), et ne contenait pas d’érythrocyte ni de leucocyte. Au terme du suivi (1 an), les résultats montrent une amélioration des scores EVA dans les deux groupes et significative pour le groupe 1 (p=0,005). Les scores VISA-P et IKDC ont tous deux augmentés, significativement dans les deux groupes. Un sujet par groupe n’a pas repris d’activité physique tandis 67% ont repris le sport au niveau antérieur dans le groupe 1 et 78% dans le groupe 2. Conclusion: La comparaison entre 1 et 2 infiltrations rapprochées de PRP n’a pas permis de mettre en évidence de différence entre les 2 groupes sur un suivi d’un an. Une seconde infiltration rapprochée ne semble donc pas indiquée pour améliorer l’efficacité de ce traitement. Cependant, un suivi à plus long terme serait nécessaire. De même l’évaluation d’une seconde infiltration plus à distance (3 mois) de la première mériterait d’être explorée. [less ▲]

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See detailIntérêt d'une stratification pédologique pour la constitution de référentiels régionaux sur les teneurs en éléments traces métalliques dans les sols de Wallonie
Colinet, Gilles ULg; Laroche, Jean; Etienne, Marie et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2004), 8(2)

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See detailIntérêt de l'acide rétinoïque "tous trans" dans le traitement de la leucémie aiguë promyélocytaire
Hermanne, J.-P.; Tassin, F.; Bours, Vincent ULg et al

in Médecine et Hygiène (1996), 54

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See detailIntérêt de l'EEG de sommeil dans les états dépressifs
PITCHOT, William ULg

in Revue Médicale de Liège (1989), 34

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See detailIntérêt de l'effort excentrique dans la rééducation des tendinopathies
Croisier, Jean-Louis ULg

in Actes du colloque «La pathologie du tendon d'Achille» (1997, November)

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See detailIntérêt de l'eLearning en contexte universitaire
Poumay, Marianne ULg

Scientific conference (2011, September 29)

Cette conférence aborde essentiellement les plus-values potentielles de l’eLearning. Elle liste des outils sans s’y étendre et montre de nombreux exemples d’activités intéressantes pour les étudiants au ... [more ▼]

Cette conférence aborde essentiellement les plus-values potentielles de l’eLearning. Elle liste des outils sans s’y étendre et montre de nombreux exemples d’activités intéressantes pour les étudiants au sein de cours en ligne. Vu le contexte particulier du Congo, elle aborde en fil rouge les questions de faisabilité de telles mises en œuvre et s'attarde sur quelques méthodes dont l'adaptation à l'UNILU pourrait être immédiate. [less ▲]

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See detailIntérêt de l'électrodermographie en psychopathologie
Gernay, Pierre; Mormont, Christian ULg

in Psychologie Médicale (1981), 13(12), 1939-1941

Tested 37 former female prisoners of war to determine if a correlation exists between the level of electrodermal activity and depression/anxiety. Four tests were administered, including some word ... [more ▼]

Tested 37 former female prisoners of war to determine if a correlation exists between the level of electrodermal activity and depression/anxiety. Four tests were administered, including some word-recognition exercises and a measure of Ss' response time. Although the results were not sufficient to warrant a diagnosis, some significant correlations of at least .05 were recognized. It is suggested that electrodermal assessment should continue to be a part of the diagnostic process. [less ▲]

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See detailIntérêt de l'électromyostimulation de basse fréquence dans la rééducation du quadriceps
Vanderthommen, Marc ULg; Constant, T.; Crielaard, Jean-Michel ULg

in Abstract book des Journées Internationales d'Electrostimulation de l'ACAPS (1990)

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See detailIntérêt de l'électromyostimulation de basse fréquence dans la rééducation du quadriceps
Constant, T.; Vanderthommen, Marc ULg

in STAPS : Revue Internationale des Sciences du Sport et de l'Education Physique (1991), 24

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See detailIntérêt de l'électromyostimulation de basse fréquence dans la rééducation du quadriceps
Vanderthommen, Marc ULg; Constant, T.; Crielaard, Jean-Michel ULg

in Abstract book du Congrès International de Médecine et de Traumatologie du Sport de Charleroi (1991)

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See detailIntérêt de l'électromyostimulation de basse fréquence dans le cadre d'un alitement prolongé
Vanderthommen, Marc ULg; COHNEN, Annette ULg; Crielaard, Jean-Michel ULg

in Pelissier, J.; Roques, C.F. (Eds.) Electrostimulation des nerfs et des muscles (1992)

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See detailIntérêt de l'enfant et paiement des pensions alimentaires après divorce en Belgique
Bawin-Legros, Bernadette; Gauthier, Anne; Guillaume, Jean-François ULg

in Population : Revue Trimestrielle de l'Institut National d'Etudes Démographiques (1991), 4

This paper is a study of parental behaviour, and more particularly that of fathers, after divorce, in which findings from a national survey carried out in Belgium are used. The payment of alimony is ... [more ▼]

This paper is a study of parental behaviour, and more particularly that of fathers, after divorce, in which findings from a national survey carried out in Belgium are used. The payment of alimony is considered to be not solely a financial solution, but as an indication of a certain acceptance of parental responsibility which is rooted in the marriage and family background that existed before the couple separated. Legal practise, which generally gives care and control of the child to the mother, also results in the continuity of the traditional type of the division of labour between the parents after their marriage has broken down. This supports the moral principle of a privileged mother-child relationship, but may also lead to a deterioration in the living standards of the mothers' households. [less ▲]

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See detailIntérêt de l'épidémiologie et des modèles animaux expérimentaux dans l'étude des valvulopathies en cardiologie humaine et équine
Leroux, Aurélia ULg

Doctoral thesis (2013)

Valvular regurgitations are one of the most common causes of cardiac diseases in humans and in domestic animals. Clinical studies, epidemiological studies, and animal experimental models have been ... [more ▼]

Valvular regurgitations are one of the most common causes of cardiac diseases in humans and in domestic animals. Clinical studies, epidemiological studies, and animal experimental models have been developed to test new diagnostic and therapeutic techniques. Electrocardiography, Doppler echocardiography, angiography, magnetic resonance imaging (MRI) and computed tomography are currently used in clinical practice for diagnosis and prognosis. Medical management and, in humans, surgical treatments can increase life expectancy and improve quality of life of cardiac patients. In horses, cardiac clinical abnormalities including murmurs and arrhythmias are relatively common while the prevalence of clinically significant cardiac diseases is low. However, investigation of these with ECG and Doppler echocardiography is recommended as even mild cardiac abnormalities may lead to significant cardiac disease and cause poor performance in sport horses. To our knowledge, risk factors for several cardiac diseases have been suspected in equids. Few have been statistically demonstrated in a large equine population, since most studies about cardiac murmurs or arrhythmias concerned only racehorses. The first aim of this research work was to perform an epidemiological study in a large equine population to describe risk factors for various cardiac diseases. The prevalence of main cardiac diseases in the studied population was in accordance with previously described prevalence as mitral regurgitation (MR), atrial fibrillation (AF), aortic regurgitation (AR) and tricuspid regurgitation (TR) were the most frequently observed cardiac diseases. Various risk factors of these cardiac diseases were statistically demonstrated: Ageing and male gender appear to predispose to AR, TR appears to affect middle-aged patients, and AF was significantly more common in larger and heavier horses. Moreover MR was an important cardiac disease since it led to congestive heart failure (CHF) whereas AR was not a direct risk factor for CHF. Functional ischemic MR is one of the main human valvular diseases and is caused by ischemic cardiomyopathy with one or more prior myocardial infarctions involving most commonly the basal posterolateral myocardium of the left ventricle (LV). The therapeutic approach to functional MR is difficult and still controversy as regards the timing and the nature of the treatment. To our knowledge, no percutaneous large animal model of functional MR has been conceptualized. This model would be the first one to allow studying the dynamic component of functional MR. Therefore the second aim of this work was the development of an experimental animal model of functional ischemic MR. Goats appeared as good candidates for the model as they fulfill all requested conditions. They have a body and heart size comparable to that of humans and can be handled easily even during exercise tests. As few publications are available in this species, three first studies were designed to test the repeatability and to establish the reference values of measurements obtained using Two-Dimensional (2D), M-Mode, Pulsed-wave (PW) Doppler and 2D speckle tracking (2DST) echocardiography in unsedated standing adult goats. Standardized echocardiographic protocols were performed three times by the same observer at one day interval on 10 to 12 goats and the intra-observer inter-day repeatability and variability was calculated. 2D and M-Mode echocardiography showed a good inter-day repeatability and a low variability of the cardiac measurements, whereas PW Doppler measurements had a poor inter-day repeatability and a moderate variability. Caprine 2DST parameters demonstrated a poor but acceptable repeatability and a high variability and allowed determination of significant physiologic differences between measurements at rest and after exercise. Then the experimental model of functional ischemic mitral regurgitation induced by a percutaneous approach in goats was developed. This experimental study was conducted in two steps: first, the study of the goat coronary arteries anatomy to determine the best myocardial infarction location to induce ischemic MR in adult Saanen goats and, secondly, the development and the imaging characterization of the goat model of functional ischemic MR. The anatomic pattern of the coronary artery system of the goat was determined using casts made of auto polymerizing resin. Two coronary arteries branches were highlighted from the results of this anatomical study: the left marginal branch (LMB) and the posterior descending branch (PDB) of the left circumflex artery, which could supply the posterolateral wall of the LV. Then myocardial infarction was induced by microcoil embolization of LMB, PDB, or both, under fluoroscopic guidance. The results confirmed that LMB and PDB occlusion produced a large myocardial infarction and an immediate severe functional MR (n=3) unlike only LMB (n=2) or only PDB occlusion (n=2). Mortality rate of this model was high (56%), particularly when LMB and PDB were simultaneously occluded (87,5%). After the myocardial infarction, a complete follow-up was performed in each surviving goat using echocardiographic techniques previously described and MRI. 2DST techniques allowed quantifying LV dysfunction during acute ischemic MR. Quantification of functional MR was performed by Doppler techniques including measurements of the vena contracta width, the effective regurgitant orifice area and the regurgitant volume using the proximal isovelocity surface area method (PISA), and by 2D-echocardiographic technique analyzing the geometrical distortion of the mitral apparatus in mid-systole (tenting area and coaptation distance). Finally, MRI confirmed the location of myocardial ischemia and the presence of functional MR. These findings make this model an interesting alternative to study the pathophysiology of the functional ischemic MR, especially for its dynamic component yielding useful prognostic information. In conclusion, the two major aims of this research were met: the prevalence of various cardiac diseases and their risk factors in a large population of equids were described and an experimental model of functional ischemic mitral regurgitation induced by a percutaneous approach in goats was developed. This model of experimental ischemic MR could be useful to further study the pathophysiology of the functional ischemic MR, especially for its dynamic component and to maximize further treatment in problem patients. Our epidemiologic study confirmed that horses with cardiac murmurs or arrhythmias and presenting demonstrated risk factors, should routinely undergo ECG and Doppler echocardiography to diagnose and to evaluate the severity of any pathological cardiac abnormalities and to identify potential signs of evolution into CHF, including the presence of multiple cardiac diseases and enlargement of the cardiac chambers. [less ▲]

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See detailIntérêt de l'étude de l'expectoration induite en pathologie pulmonaire
Kayembe, J. M.; Louis, Renaud ULg; Bury, Thierry ULg et al

in Revue Médicale de Liège (1995), 50(5), 209-12

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See detailIntérêt de l'étude de la VCN dans les migraines et les céphalées de tension.
Timsit, M.; Timsit-Berthier, M.; Schoenen, Jean ULg et al

in Revue d'Eléctroencephalographie et de Neurophysiologie Clinique (1987), 17(3), 259-70

The aim of this study was to display the result obtained by the contingent negative variation (CNV) recording in patients suffering from headache. Eighty-five patients were taken into account: 59 with ... [more ▼]

The aim of this study was to display the result obtained by the contingent negative variation (CNV) recording in patients suffering from headache. Eighty-five patients were taken into account: 59 with migraines (M) and 26 with tension headache (TH). A typical CNV pattern (high CNV amplitude with no habituation) differentiated M from TH. Moreover, psychological data were collected through Rorschach ink blot test among 42 headache sufferers (31 M and 11 TH). The typical Rorschach repressive pattern of alexithymia was found as well in M as in TH while CNV amplitude was significantly higher in the 31 M (-25 microV) than in the 11 TH (-19 microV FP less than 0.04). Biochemical data collected among 28 patients (17 M and 11 TH) revealed a positive correlation between CNV amplitude and plasma level of noradrenaline, regardless of the type of headache (r = 0.58; P less than 0.01). Thus, besides psychological factors, catecholaminergic mechanisms seem implicated in the determination of the CNV pattern in migraine. CNV may help the clinician both to specify diagnosis and to decide between the many therapeutic strategies available. [less ▲]

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