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See detailIs there value in maintaining small populations ? Example of the Dual-Purpose Belgian Blue breed.
Gengler, Nicolas ULg; Soyeurt, Hélène ULg; Bastin, Catherine ULg et al

Conference (2011, July 13)

Current status of thinking on genomic selection in dairy cattle is mostly major breed centric (e.g., Holstein) and only for traditional traits (e.g., milk yields). Once you depart from this, it becomes ... [more ▼]

Current status of thinking on genomic selection in dairy cattle is mostly major breed centric (e.g., Holstein) and only for traditional traits (e.g., milk yields). Once you depart from this, it becomes obvious that different, often related, issues appear (e.g., lack of large training populations, need for expensive recording of new phenotypes). Also, there is an urgent need to rethink issues that are important for sustainability of dairy production (e.g., added value foods, animal robustness). In this context, small populations (breeds/lines) could represent a potential source of extra information to justify their maintenance. As marker densities increase, efficient dissection of different selection histories of divergent breeds or lines, potentially identifying pockets of unexploited variability will increase. A current example from the Belgian (Walloon) perspective is the Dual Purpose (DP) line of the Belgian Blue Breed (BBB), with presently around 4500 breeding females, for historical reason of which only 1500 have good pedigrees, and which is present in Belgium and northern France. Recent research, done on this line, showed its tendency to produce less saturated milk fat and to have better fertility. Results indicated that it could stay competitive in specific markets, especially because of largely increased meat value. Currently, the myostatin mutation is largely used for breeding purposes. To assess the genetic diversity of the breed, recently, over 200 genotypes (SNP50K) for nearly all breeding bulls of the last 20 years became available. HD genotypes should be available in the near future, also allowing to access selection history of this breed as being in between the 2 extreme breeds: Beef BBB (with which it shares a recent history) and Holstein-Friesian (which is related through its geographic proximity over centuries). Finally, genomic selection for DP-BBB will need to consider a single step type approach without the need of reference population and potentially relying heavily on SNP3K of cows, also with the objective to recreate relationships between animals of interest. [less ▲]

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See detailIs there value in maintaining small populations ? Example of the Dual-Purpose Belgian Blue breed.
Gengler, Nicolas ULg; Soyeurt, Hélène ULg; Bastin, Catherine ULg et al

in Journal of Dairy Science (2011), 94(E-suppl.1), 664

Current status of thinking on genomic selection in dairy cattle is mostly major breed centric (e.g., Holstein) and only for traditional traits (e.g., milk yields). Once you depart from this, it becomes ... [more ▼]

Current status of thinking on genomic selection in dairy cattle is mostly major breed centric (e.g., Holstein) and only for traditional traits (e.g., milk yields). Once you depart from this, it becomes obvious that different, often related, issues appear (e.g., lack of large training populations, need for expensive recording of new phenotypes). Also, there is an urgent need to rethink issues that are important for sustainability of dairy production (e.g., added value foods, animal robustness). In this context, small populations (breeds/lines) could represent a potential source of extra information to justify their maintenance. As marker densities increase, efficient dissection of different selection histories of divergent breeds or lines, potentially identifying pockets of unexploited variability will increase. A current example from the Belgian (Walloon) perspective is the Dual Purpose (DP) line of the Belgian Blue Breed (BBB), with presently around 4500 breeding females, for historical reason of which only 1500 have good pedigrees, and which is present in Belgium and northern France. Recent research, done on this line, showed its tendency to produce less saturated milk fat and to have better fertility. Results indicated that it could stay competitive in specific markets, especially because of largely increased meat value. Currently, the myostatin mutation is largely used for breeding purposes. To assess the genetic diversity of the breed, recently, over 200 genotypes (SNP50K) for nearly all breeding bulls of the last 20 years became available. HD genotypes should be available in the near future, also allowing to access selection history of this breed as being in between the 2 extreme breeds: Beef BBB (with which it shares a recent history) and Holstein-Friesian (which is related through its geographic proximity over centuries). Finally, genomic selection for DP-BBB will need to consider a single step type approach without the need of reference population and potentially relying heavily on SNP3K of cows, also with the objective to recreate relationships between animals of interest. [less ▲]

Detailed reference viewed: 27 (11 ULg)
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See detailIs thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs ?
Robert, S.; Ghiotto, J.; Pirotte, Bernard ULg et al

in Pharmacological Research (2009), 59

Detailed reference viewed: 16 (3 ULg)
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See detailIs thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs?
Robert, S.; Ghiotto, J.; Pirotte, Bernard ULg et al

Conference (2009, November)

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See detailIs transforming growth factor- beta 1 involved in the pathogenesis of IPF in dogs ?
Krafft, Emilie ULg; Heikkilä, H. P.; De Lorenzi, D. et al

in Proceedings of the 20th Annual Congress of the ECVIM-CA (2010)

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See detailIs ultra-short cold ischemia the key to IBDL avoidance in DCD-LT?
DETRY, Olivier ULg; DE ROOVER, Arnaud ULg; Ledinh, Hieu et al

Poster (2013, February 08)

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See detailIS ULTRA-SHORT COLD ISCHEMIA THE KEY TO ISCHEMIC CHOLANGIOPATHY AVOIDANCE IN DCD- LT?
DETRY, Olivier ULg; DE ROOVER, Arnaud ULg; Cheham, Samir et al

in Transplant International (2013, December), 26(S2), 53-98

Introduction: Donation after circulatory death (DCD) donors have been proposed to partially overcome the organ donor shortage. DCD-LT remains controversial, with reported increased risk of ischemic ... [more ▼]

Introduction: Donation after circulatory death (DCD) donors have been proposed to partially overcome the organ donor shortage. DCD-LT remains controversial, with reported increased risk of ischemic cholangiopathy leading to graft loss. The authors retrospectively reviewed a single centre experience with DCD-LT in a 9-year period. Patients and Methods: 70 DCD-LT were performed from 2003 to November 2012. All DCD procedures were performed in operative rooms. Median donor age was 59 years. Most grafts were flushed with HTK solution. Allocation was centre-based. Median total DCD warm ischemia was 19.5 min. Mean follow-up was 36 months. No patient was lost to follow-up. Results: Median MELD score at LT was 15. Median cold ischemia was 235 min. Median peak AST was 1,162 U/L. Median peak bilirubin was 31.2 mg/dL. Patient and graft survivals were 92.8% and 91.3% at one year and 79% and 77.7% at 3 years, respectively. One graft was lost due to hepatic artery thrombosis. No PNF or graft loss due to ischemic cholangiopathy was observed in this series. Causes of death were malignancies in 8 cases. Discussion: In this series, DCD LT appears to provide results equal to classical LT. Short cold ischemia and recipient selection with low MELD score may be the keys to good results in DCD LT, in terms of graft survival and avoidance of ischemic cholangiopathy. [less ▲]

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See detailIs ultra-short cold ischemia the key to ischemic cholangiopathy avoidance in DCD-LT?
DETRY, Olivier ULg; DE ROOVER, Arnaud ULg; Cheham, S et al

in Acta Chirurgica Belgica (2013, May), Supplement 113(3), 6729

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See detailIs volition the missing link in the management of low back pain?
Broonen, Jean-Paul ULg; Marty, Marc; Legout, Virgine et al

in Joint Bone Spine (2011), 78

Patients with nonspecific chronic low back pain are typically prescribed a regimen of regular physical exercises to improve pain and function, increase workability, and prevent pain recurrence. However ... [more ▼]

Patients with nonspecific chronic low back pain are typically prescribed a regimen of regular physical exercises to improve pain and function, increase workability, and prevent pain recurrence. However, adherence to home exercise programs is often partial at best. Patients often fail to translate their intention to exercise (motivation) into action (implementation). Volition is the mental activity by which intentions are implemented. In this review, we argue that volition may be crucial to the successful rehabilitation of patients with low back pain. Obstacles to the implementation of intentions are described, as well as factors that promote implementation, most notably the conscious formation of implementation intentions. [less ▲]

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See detailIs your company oriented toward strategic intelligence?
Brandt, Céline ULg; Gretry, Anaïs ULg; Gruslin, Claire ULg

Article for general public (2012)

If you wonder if your company is active in the different fields of strategic intelligence and which are its strengths and weaknesses, this questionnaire will help you to do so.

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See detailIs1151, an Is-Like Element of Clostridium Perfringens
Daube, Georges ULg; Kaeckenbeeck, Albert ULg; Simon, Patricia ULg

in Nucleic Acids Research (1993), 21(2), 352

Description of a new insertion sequence, named IS1151, associated with cpe gene from Clostridium perfringens

Detailed reference viewed: 25 (8 ULg)
See detailIsaac Bashevis Singer, ou la littérature comme illustration d'une théorie du droit
Thirion, Nicolas ULg

in Liber amicorum Paul Martens. L'humanisme dans la résolution des conflits. Utopie ou réalité? (2007)

Illustration de la théorie de la pluralité des ordres juridiques de Santi Romano par une nouvelle d'Isaac Bashevis Singer tiré du recueil "Au tribunal de mon père"

Detailed reference viewed: 22 (2 ULg)
See detailIsaac Newton
De Rop, Yves ULg

Article for general public (1994)

Not Available

Detailed reference viewed: 22 (4 ULg)
See detailIsabel Stuart, Duchess of Brittany
L'Estrange, Elizabeth ULg

in Viennot, Elianne (Ed.) Dictionnaire des femmes de l'Ancien Régime (2006)

Detailed reference viewed: 49 (3 ULg)
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See detailISADYLE : Instrument pour le screening et l'examen approfondi des dysfonctionnement du langage chez l'enfant
Pierart, Bernadette; Comblain, Annick ULg; Grégoire, Jacques et al

Poster (1997, April 25)

ISADYLE est un nouvel instrument d'évaluation du développement du langage chez l'enfant. Il est également un outil diagnostic des pathologies du développement du langage. Constitué sur base d'un ... [more ▼]

ISADYLE est un nouvel instrument d'évaluation du développement du langage chez l'enfant. Il est également un outil diagnostic des pathologies du développement du langage. Constitué sur base d'un échantillon de 1200 enfants belges, ISADYLE est le premier outil belge fait par des logopèdes à l'usage des logopèdes. Il passe en revue toutes les facettes du langage oral de 3 à 12 ans [less ▲]

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See detailIsadyle : Manuel d'application
Piérat, Bernadette; Comblain, Annick ULg; Grégoire, Jacques et al

Book published by Solal (2010)

ISADYLE est une batterie de langage construite en appui sur les théories développementales de la parole, du lexique, de la syntaxe et de la métalinguistique chez l’enfant. La batterie ISADYLE comporte ... [more ▼]

ISADYLE est une batterie de langage construite en appui sur les théories développementales de la parole, du lexique, de la syntaxe et de la métalinguistique chez l’enfant. La batterie ISADYLE comporte deux parties complémentaires : une batterie abrégée (screening) destinée au bilan en première ligne, rapide, du lexique, de la phonologie et de la syntaxe et une batterie approfondie consacrée à l’analyse soigneuse des structures et du fonctionnement des divers modules dont l’intégration permet un exercice harmonieux du langage. La batterie approfondie offre le choix parmi 52 épreuves. Chaque épreuve a fait l’objet d’un étalonnage distinct. Le clinicien sélectionnera parmi ces épreuves celles qui sont les plus pertinentes pour affiner l’évaluation des diverses facettes du langage de son patient, en fonction de ses objectifs diagnostiques et thérapeutiques. Ces outils sont destinés aux enfants de 3 à 12 ans. La batterie a été élaborée par quatre enseignants et chercheurs impliqués dans les programmes de formation des masters en logopédie des universités belges. [less ▲]

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See detailIsadyle : Un nouvel instrument d'évaluation du langage
Comblain, Annick ULg; Piérart, Bernadette

Conference (2001, August 05)

La batterie Isadyle Piérart B., Comblain A., Grégoire J., Mousty Ph., Noel M-P. Les batteries de langage oral en langue française reposent sur des bases théoriques datant au plus tard de 1962 . Elles ne ... [more ▼]

La batterie Isadyle Piérart B., Comblain A., Grégoire J., Mousty Ph., Noel M-P. Les batteries de langage oral en langue française reposent sur des bases théoriques datant au plus tard de 1962 . Elles ne présentent qu'un seul niveau d'analyse. Les étalonnages s'étendent de 8 ans. La recherche poursuit quatre objectifs : - (a) construire une batterie longue de langage oral, destinée à l' examen approfondi des dysfonctionnements du langage de l'enfant ; - (b) construire une batterie courte de langage oral, à partir des items statistiquement les plus discriminants ; - (c) réaliser des étalonnages corrects sur échantillons proportionnels stratifiés en Belgique francophone, ce qui répond également aux besoins de la sécurité sociale en matière de logopédie de l'enfant; - (d) constituer une banque de données longitudianles et transversales sur le lanngage oral de 1200 enfants de 3 à 12 ans [less ▲]

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See detailIschaemic Colitis Following Aortoiliac Surgery
VAN DAMME, Hendrik ULg; CREEMERS, Etienne ULg; Limet, Raymond ULg

in Acta Chirurgica Belgica (2000), 100(1), 21-7

Ischaemic colitis following aortoiliac surgery is a feared complication. Its frequency varies from 7% after repair of ruptured abdominal aortic aneurysm (AAA) to 0.6% after bypass for aortoiliac occlusive ... [more ▼]

Ischaemic colitis following aortoiliac surgery is a feared complication. Its frequency varies from 7% after repair of ruptured abdominal aortic aneurysm (AAA) to 0.6% after bypass for aortoiliac occlusive disease (AOD). In order to analyse predisposing factors and outcome of ischaemic colitis, the authors reviewed their clinical experience from 1988 to 1998. It concerns 28 cases (16 ruptured AAA, 7 elective AAA, 5 OAD) of clinically evident colonic ischaemia. This means an incidence of 7% after repair of ruptured AAA, 0.6% after elective AAA repair, and 0.8% after bypass for AOD. Transmural necrosis (grade 3) was observed in 21 patients, grade 2 ischaemia in 5 patients, and grade 1 ischaemia in 2 patients. Fifteen patients with grade 3 ischaemia underwent colectomy (Hartmann's procedure) with a mortality rate of 66%. All non operated grade 3 patients died. Overall, 16 of the 28 patients died at hospital (57% mortality rate). None of the patients with mild (grade 2 or 1) colonic ischaemia died. Profound hypovolaemic shock and inflammatory AAA were the only significant predisposing factors leading to colonic ischaemia. Associated colon revascularization could not avoid the evolution to colon necrosis in four patients. Reimplantation of a patent inferior mesenteric artery or an internal iliac artery was performed in only 4.8% of all aortoiliac reconstructions, and did not influence the development of ischaemic colitis. The authors conclude that a more liberal use of postoperative sigmoidoscopy could allow detecting colonic ischaemia at an earlier stage and reduce ensuing mortality. A reinforced effort to restore or preserve colonic vascularization could lower the incidence of colonic ischaemia following aortoiliac surgery. [less ▲]

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See detailIschaemic mitral regurgitation: mechanisms and diagnosis.
Marwick, Th; Lancellotti, Patrizio ULg; Pierard, Luc ULg

in Heart (2009), 95(20), 1711-8

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See detailIschaemic mitral regurgitation: pathophysiology, outcomes and the conundrum of treatment.
PIERARD, Luc ULg; Carabello, B. A.

in European Heart Journal (2010), 31

Ischaemic mitral regurgitation is a frequent complication of left ventricular global or regional pathological remodelling due to chronic coronary artery disease. It is not a valve disease but represents ... [more ▼]

Ischaemic mitral regurgitation is a frequent complication of left ventricular global or regional pathological remodelling due to chronic coronary artery disease. It is not a valve disease but represents the valvular consequences of increased tethering forces (papillary muscles displacement leading to a more apical position of the leaflets and their coaptation point) and reduced closing forces (reduced contractility, dyssynchrony of the papillary muscles, intra-left ventricular dyssynchrony). Although mitral regurgitation has an unloading effect and reduces impedance, the volume overload begets further left ventricular dilatation, increases ventricular wall stress leading to worsened performance. Ischaemic mitral regurgitation is characteristically dynamic: its severity may vary with haemodynamic conditions. Both the severity of ischaemic mitral regurgitation and its dynamic component worsen prognosis. There are numerous possible treatment modalities, but the management of the individual patient remains difficult. Medical therapy is mandatory; revascularization procedures are frequently not sufficient to reduce mitral regurgitation; the role of combined surgical therapy by mitral valve repair is not yet defined in the absence of large randomized trial. Some patients are good candidates for cardiac resynchronization therapy that may reduce the amount of regurgitation. New therapeutic targets are under investigation. [less ▲]

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