Browsing Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others      by title 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z or enter first few letters:    OK Showing results 57835 to 57854 of 148514     2887 2888 2889 2890 2891 2892 2893 2894 2895 2896 2897     First study of oral artenimol-R in advanced cervical cancer: clinical benefit, tolerability and tumor markersJansen, Frans Herwig; Adoubi, Innocent; Kouassi, Comoe J.C. et alin Anticancer Research (2011), 31(12), 4417-4422Background/Aim: Artenimol-R is cytotoxic in transformed cervical cells and safety in humans is yet to be established. The present study investigates the clinical benefits, safety and the tumor marker ... [more ▼]Background/Aim: Artenimol-R is cytotoxic in transformed cervical cells and safety in humans is yet to be established. The present study investigates the clinical benefits, safety and the tumor marker effect of orally administered Artenimol-R in patients with advanced cervix carcinoma. Patients and Methods: Ten patients were treated with Artenimol-R for 28 days. Clinical symptoms, vaginal discharge and pain were followed-up. Adverse events were recorded. Biopsy samples were analyzed by immunohistochemistry for the expression of relevant tumor markers. Results: Artenimol-R treatment induced clinical remission with a median time for the disappearance of the symptoms being 7 days. No adverse events of grade 3 or 4 occurred. The expression of p53, Epidermal growth factor receptor (EGFR), and antigen Ki-67 as a cellular marker of proliferation, as well as the number of blood vessels stained by the CD31 antibody decreased, whereas the expression of transferrin receptor protein 1 (CD71) increased. Conclusion: The current pilot study provides evidence on the improvement of the clinical symptoms and the good tolerability of Artenimol-R in patients with advanced carcinoma of the cervix uteri. A survival trial with Artenimol- R in advanced patients is warranted. [less ▲]Detailed reference viewed: 48 (2 ULg) The first successful crystallization of a prokaryotic extremely thermophilic outer surface layer glycoproteinEvrard, Christine ; Declercq, Jean-Paul; Debaerdemaeker, Tony et alin Zeitschrift für Kristallographie (1999), 214Methanothermus fervidus belongs to the group of hyperthermophilic Archaea. The Archaea comprise organisms that live under environmental extremes. like high temperature, low pH value or high salt ... [more ▼]Methanothermus fervidus belongs to the group of hyperthermophilic Archaea. The Archaea comprise organisms that live under environmental extremes. like high temperature, low pH value or high salt concentration. The outer surface of the pseudomurein sacculi of the cells of Methanothermus fervidus is covered by glycoprotein subunits (S-Iayer) directly exposed to the extreme environment. The elucidation of the crystal structure of this surface glycoprotein may provide important information on the survival strategies of these unusual micro-organisms. Before our investigations neither three-dimensional crystals have been obtained nor X-ray analyses were performed. Only electron microscopic and computer image enhancement techniques have been applied to obtain structural information from crystalline two-dimensional S-layer sheets. We describe here the successful crystallization of this surface glycoprotein under microgravity conditions. [less ▲]Detailed reference viewed: 31 (1 ULg) First supplement to the catalog of observed periods of AP starsCatalano, F. A.; Renson, Pierre in Astronomy and Astrophysics. Supplement Series (1988), 72Supplementary data on the periods of Ap stars with references are presented; 58 new stars are introduced for which periodic variability has been discovered since 1983. For some of these stars periodicity ... [more ▼]Supplementary data on the periods of Ap stars with references are presented; 58 new stars are introduced for which periodic variability has been discovered since 1983. For some of these stars periodicity was known before 1983 but they were not reported in the previous catalogue. Recently attributed variable star names are also reported. [less ▲]Detailed reference viewed: 10 (1 ULg) First survey on prevalence and infestation rates of Varrroa mite in GabonFabre Anguilet, Edgard ; Alabi, Taofic ; Bengone Ndong, Toussaint et alin Communications in Agricultural and Applied Biological Sciences (2016), 81(3), 299-305Varroa mites cause considerable damage to Apis mellifera Linnaeus colonies in North America, Europe and Asia. To control this parasite, beekeepers in these parts of world have to use chemical acaricides ... [more ▼]Varroa mites cause considerable damage to Apis mellifera Linnaeus colonies in North America, Europe and Asia. To control this parasite, beekeepers in these parts of world have to use chemical acaricides. In Africa, this pest has been identified, and survey of Varroa infestation rates showed a lot of variation across honey bee sub-species. Generally, African colonies seemed to be resistant or tolerant to the presence of Varroa mite. The objective of our study is to explore the presence, prevalence and infestation rates of Varroa mite in Gabon. The presence and quantitative assessment of Varroa mites were performed in 55 wild colonies of Apis mellifera adansonii Latreille in two locations. Our results showed that: (1) 70% and 48% of the wild colonies studied were infested with Varroa destructor according to locations, (2) Varroa infestation rate was lower than 0.5 mite per 100 bees regardless location. The infestation rates obtained were still very low compared to those observed in various other regions in Africa. In perspective, it would be interesting to explore the reasons that could explain the low infestation rates which were observed. [less ▲]Detailed reference viewed: 22 (5 ULg) First Survey on the Use of Antibiotics in Pig and Poultry Production in the Red River Delta Region of VietnamPham Kim, Dang; Saegerman, Claude ; Douny, Caroline et alin Food and Public Health (2013), 3(5), 247-256In Vietnam where epidemics occur regularly in animal production, the farmers consider antibiotics as one of the solutions to fight against livestock diseases, thus the risk of abuse, even illegal use of ... [more ▼]In Vietnam where epidemics occur regularly in animal production, the farmers consider antibiotics as one of the solutions to fight against livestock diseases, thus the risk of abuse, even illegal use of antibiotics in livestock is very high. However, this is a recent issue and has not yet been thoroughly investigated. A cross-sectional study on the use of antibiotics in pig and poultry production as well as the farmer’s knowledge on the danger of the antibiotic use in three different animal production systems (farm household, semi-industrial and industrial) was conducted from July 2009 to March 2010 on 270 entities, in 3 representative localities of the Red River Delta (RRD). The results showed that a large volume of antibiotics was used arbitrary in all animal production systems. Animals were not only treated for acute diseases, but also for disease prevention, and for growth promotion. At least 45 antibiotics of more than 10 classes were used. Fifteen antibiotics were used in pig and poultry feed. For diseases treatment and prevention, antibiotics were used abusively and even illegally (e.g. chloramphenicol) by both farmers and veterinarians. The findings of this survey will permit developing new strategies for prudent use of antibiotics in livestock in Vietnam. These results will help not only to strengthen issues such as veterinary networks; antibiotics use guidance, residues monitoring systems and food safety, but also to improve awareness and ethics of producers and veterinary drug sellers. [less ▲]Detailed reference viewed: 137 (6 ULg) First synthesis of 4-substituted benzenesulfonylcyanoguanidinesMasereel, B.; Lebrun, P.; Dogne, J.-M. et alin Tetrahedron Letters (1996), 37Detailed reference viewed: 11 (0 ULg) First synthesis of a '1,2-diquinone-calix[4]arene'. Interaction of its reduced form with Ag+Vataj, Rame; Ridaoui, Hassan; Louati, Alain et alin Journal of Electroanalytical Chemistry (2002), 519(1-2), 123129Electrochemical oxidation of 5,11,17,23-tetra-tert-butyl-25,26-bis(diphenylphosphinoylmethoxy)-27,28-dihydroxycalix[4]arene (3), a calixarene with two phosphoryl units appended on proximal positions ... [more ▼]Electrochemical oxidation of 5,11,17,23-tetra-tert-butyl-25,26-bis(diphenylphosphinoylmethoxy)-27,28-dihydroxycalix[4]arene (3), a calixarene with two phosphoryl units appended on proximal positions, affords the corresponding '1,2-diquinonecalix[4]arene' (4). The formation of 4 results from nucleophilic attack of residual water on anodically generated diphenoxylium. cations. Preliminary voltammetric experiments in CH3CN on a platinum electrode showed that 4 is suitable for electrochemical detection of the silver metal cation. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]Detailed reference viewed: 116 (6 ULg) The first three billion years of life EvolutionJavaux, Emmanuelle Conference (2013, June)Detailed reference viewed: 43 (4 ULg) First three dimensional structure of a psychrophilic enzyme : an alpha-amylase from the antarctic psychrophile Alteromonas haloplanctisAghajari, Nushin; Feller, Georges ; Gerday, Charles et alPoster (1997)Detailed reference viewed: 15 (1 ULg) First trends towards a field odour detector for environmental applicationsNicolas, Jacques ; Romain, Anne-Claude ; Wiertz, V. et alin Weimar, Udo (Ed.) Proceedings of ISOEN 99 (1999)Detailed reference viewed: 23 (2 ULg) First two years of results from a mooring over a Posidonia Oceanica seagrass meadow (Corsica, France)Champenois, Willy ; Delille, Bruno ; Beckers, Jean-Marie et alPoster (2009)Detailed reference viewed: 16 (4 ULg) First two years of results from a mooring over a Posidonia Oceanica seagrass meadow (Corsica, France)Champenois, Willy ; Delille, Bruno ; Beckers, Jean-Marie et alConference (2009, May)Detailed reference viewed: 23 (6 ULg) First unambiguous asteroseismologic modelling of a gamma Doradus starMoya, A.; Grigahcene, A.; Suárez, J. C. et alin Memorie della Società Astronomica Italiana : Journal of the Italian Astronomical Society (2006), 77An asteroseismologic model of the gamma Dor star 9 Aurigae is discussed in this work. This is the first time a complete asteroseismologic scheme for analyzing gamma Dor stars is applied. From standard ... [more ▼]An asteroseismologic model of the gamma Dor star 9 Aurigae is discussed in this work. This is the first time a complete asteroseismologic scheme for analyzing gamma Dor stars is applied. From standard photometric observations (at least three oscillation frequencies, a photometric error box in the HR diagram and multicolor photometric observations, in this case in the Strömgren system) we can reduce the possible theoretical models for this star, providing constraints to the stellar parameters as mass, overshooting, metallicity, MLT parameter alpha , Brunt-Väiälä integral (I[SUB]th[/SUB]), etc. Simultaneously, an estimate of the modal identification of the observed frequencies is also obtained. This can be possible by the application, for the first time, of a complete procedure where different theoretical and computational techniques, recently developed, are linked and compared with photometric observations. The Frequency Ratio Method (FRM) and the Time Dependent Convection (TDC) theory are the basis of this complete procedure. [less ▲]Detailed reference viewed: 9 (2 ULg) The first Upper Paleolithic human remains from Belgium: Aurignacian, Gravettian and Magdalenian fossils at the “troisième caverne” of GoyetRougier, H.; Crevecoeur, I.; Beauval, C. et alPoster (2013)Detailed reference viewed: 120 (2 ULg) First vortex entry into a perpendicularly magnetized superconducting thin filmGutierrrez, Joffre; Raes, Bart; Van de Vondel, Joris et alin Physical Review. B : Condensed Matter (2013), 88In type-II superconductors, the flux-free state (Meissner state) may be invaded by vortices bearing quantized flux once H is above the lower critical field Hc1. However, the actual first flux penetration ... [more ▼]In type-II superconductors, the flux-free state (Meissner state) may be invaded by vortices bearing quantized flux once H is above the lower critical field Hc1. However, the actual first flux penetration does not occur at Hc1 due to the presence of a surface barrier and the fact that the Meissner state may also exist as a metastable state up to a larger (superheating) field. In this work we determine the field for the first vortex penetration in superconductors, by directly imaging the first vortex threading a superconducting Pb film with antidots. We find that the first vortex penetration occurs when the surface superconducting currents reach the depairing current, locally breaking superconductivity and allowing a vortex to nucleate. [less ▲]Detailed reference viewed: 34 (0 ULg) The First World War in French Children's Literature of Today: Between Pacifism and Unilateral ViewDelbrassine, Daniel in Hans-Heino Ewers (Ed.) Erster Weltkrieg: Kindheit, Jugend und Literatur (2016)Analyse d'un corpus de 22 récits (albums et romans en français, 1998-2013). Mise en évidence de certains choix narratifs et idéologiques: unilatéralisme français de la vision, pacifisme militant, silence ... [more ▼]Analyse d'un corpus de 22 récits (albums et romans en français, 1998-2013). Mise en évidence de certains choix narratifs et idéologiques: unilatéralisme français de la vision, pacifisme militant, silence sur les causes du conflit... [less ▲]Detailed reference viewed: 19 (2 ULg) The first X-ray survey of Galactic Luminous Blue VariablesNazé, Yaël ; Rauw, Grégor ; Hutsemekers, Damien in Astronomy and Astrophysics (2012), 538Aims: The X-ray emission of massive stars has been studied when these objects are in their main-sequence phase, as well as in their Wolf-Rayet phase. However, the X-ray properties of the transitional ... [more ▼]Aims: The X-ray emission of massive stars has been studied when these objects are in their main-sequence phase, as well as in their Wolf-Rayet phase. However, the X-ray properties of the transitional Luminous Blue Variable (LBV) phase remain unknown. Methods: Using a dedicated but limited XMM survey as well as archival XMM and Chandra observations, we performed the first X-ray survey of LBVs: about half of the known LBVs or candidate LBVs are studied. Results: Apart from the well known X-ray sources eta Car and Cyg OB2 #12, four additional LBVs are detected in this survey, though some doubt remains on the association with the X-ray source for two of these. For the other LBVs, upper limits on the flux were derived, down to $\log[L_{\rm X}/L_{\rm BOL}]-9.4$ for PCyg. This variety in the strength of the X-ray emission is discussed, with particular emphasis on the potential influence of binarity. [less ▲]Detailed reference viewed: 36 (1 ULg) First year of results from a mooring over a Posidonia Oceanica seagrass meadow (Corsica, France)Borges, Alberto ; Delille, Bruno ; Beckers, Jean-Marie et alConference (2008, April)Detailed reference viewed: 14 (1 ULg) First year prognosis after myocardial infarction assassed from simple clinical findingsSmeets, J. P.; Foidart, G.; Dubois, Christophe et alPoster (1982, September)Detailed reference viewed: 16 (1 ULg) First ‘in situ’ determination of gas transport coefficients (DO2, DAr and DN2 ) from bulk gas 2 concentration measurements (O2, N2, Ar) in natural sea iceCrabeck, O.; Delille, Bruno ; Rysgaard, S. et alin Journal of Geophysical Research. Oceans (2014), 119We report bulk gas concentrations of O2, N2 and Ar, as well as their transport coefficients, in natural landfast subarctic sea ice in southwest Greenland. The observed bulk ice gas composition was 27.5 ... [more ▼]We report bulk gas concentrations of O2, N2 and Ar, as well as their transport coefficients, in natural landfast subarctic sea ice in southwest Greenland. The observed bulk ice gas composition was 27.5% O2, 71.4% N2 and 1.09% Ar. Most previous studies suggest that convective transport is the main driver of gas displacement in sea ice and have neglected diffusion processes. According to our data, brines were stratified within the ice, so that no convective transport could occur within the brine system. Therefore, diffusive transport was the main driver of gas migration. By analysing the temporal evolution of an internal gas peak within the ice, we deduced the bulk gas transport coefficients for oxygen (DO2), argon (DAr) and nitrogen (DN222 ). The values fit to the few existing estimates from experimental work, and are close to the diffusivity values in water (10-5 cm2 s-124 ). We suggest that gas bubbles escaping from the brine to the atmosphere - as the ice gets more permeable during melt could be responsible for the previously reported high transport coefficients. These results underline that when there is no convective transport within the sea ice, the transport of gas by diffusion through the brines, either in the liquid or gaseous phases, is a major factor in controlling the ocean–atmosphere exchange. [less ▲]Detailed reference viewed: 16 (0 ULg)